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Items: 6

1.

Genetic Modifiers at the Crossroads of Personalised Medicine for Haemoglobinopathies.

Stephanou C, Tamana S, Minaidou A, Papasavva P, Kleanthous M, Kountouris P.

J Clin Med. 2019 Nov 9;8(11). pii: E1927. doi: 10.3390/jcm8111927.

2.

Correction of IVS I-110(G>A) β-thalassemia by CRISPR/Cas-and TALEN-mediated disruption of aberrant regulatory elements in human hematopoietic stem and progenitor cells.

Patsali P, Turchiano G, Papasavva P, Romito M, Loucari CC, Stephanou C, Christou S, Sitarou M, Mussolino C, Cornu TI, Antoniou MN, Lederer CW, Cathomen T, Kleanthous M.

Haematologica. 2019 Nov;104(11):e497-e501. doi: 10.3324/haematol.2018.215178. Epub 2019 Apr 19. No abstract available.

3.

Rare Opportunities: CRISPR/Cas-Based Therapy Development for Rare Genetic Diseases.

Papasavva P, Kleanthous M, Lederer CW.

Mol Diagn Ther. 2019 Apr;23(2):201-222. doi: 10.1007/s40291-019-00392-3. Review.

4.

Short-hairpin RNA against aberrant HBBIVSI-110(G>A) mRNA restores β-globin levels in a novel cell model and acts as mono- and combination therapy for β-thalassemia in primary hematopoietic stem cells.

Patsali P, Papasavva P, Stephanou C, Christou S, Sitarou M, Antoniou MN, Lederer CW, Kleanthous M.

Haematologica. 2018 Sep;103(9):e419-e423. doi: 10.3324/haematol.2018.189357. Epub 2018 Apr 26. No abstract available.

5.

Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies.

Loucari CC, Patsali P, van Dijk TB, Stephanou C, Papasavva P, Zanti M, Kurita R, Nakamura Y, Christou S, Sitarou M, Philipsen S, Lederer CW, Kleanthous M.

Hum Gene Ther Methods. 2018 Feb;29(1):60-74. doi: 10.1089/hgtb.2017.190.

6.

Suitability of small diagnostic peripheral-blood samples for cell-therapy studies.

Stephanou C, Papasavva P, Zachariou M, Patsali P, Epitropou M, Ladas P, Al-Abdulla R, Christou S, Antoniou MN, Lederer CW, Kleanthous M.

Cytotherapy. 2017 Feb;19(2):311-326. doi: 10.1016/j.jcyt.2016.11.007.

PMID:
28088294

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