Sort by
Items per page

Send to

Choose Destination

Search results

Items: 31


Depletion of Ras Suppressor-1 (RSU-1) promotes cell invasion of breast cancer cells through a compensatory upregulation of a truncated isoform.

Gkretsi V, Kalli M, Efstathiades C, Papageorgis P, Papanikolaou V, Zacharia LC, Tsezou A, Athanassiou E, Stylianopoulos T.

Sci Rep. 2019 Jul 11;9(1):10050. doi: 10.1038/s41598-019-46575-0.


Dexamethasone Increases Cisplatin-Loaded Nanocarrier Delivery and Efficacy in Metastatic Breast Cancer by Normalizing the Tumor Microenvironment.

Martin JD, Panagi M, Wang C, Khan TT, Martin MR, Voutouri C, Toh K, Papageorgis P, Mpekris F, Polydorou C, Ishii G, Takahashi S, Gotohda N, Suzuki T, Wilhelm ME, Melo VA, Quader S, Norimatsu J, Lanning RM, Kojima M, Stuber MD, Stylianopoulos T, Kataoka K, Cabral H.

ACS Nano. 2019 Jun 25;13(6):6396-6408. doi: 10.1021/acsnano.8b07865. Epub 2019 Jun 12.


MicroRNA-4417 is a tumor suppressor and prognostic biomarker for triple-negative breast cancer.

Wong CK, Gromisch C, Ozturk S, Papageorgis P, Abdolmaleky HM, Reinhard BM, Thiagalingam A, Thiagalingam S.

Cancer Biol Ther. 2019;20(8):1113-1120. doi: 10.1080/15384047.2019.1595285. Epub 2019 Mar 28.


NAA40 contributes to colorectal cancer growth by controlling PRMT5 expression.

Demetriadou C, Pavlou D, Mpekris F, Achilleos C, Stylianopoulos T, Zaravinos A, Papageorgis P, Kirmizis A.

Cell Death Dis. 2019 Mar 11;10(3):236. doi: 10.1038/s41419-019-1487-3.


Activin A Signaling Regulates IL13Rα2 Expression to Promote Breast Cancer Metastasis.

Kalli M, Mpekris F, Wong CK, Panagi M, Ozturk S, Thiagalingam S, Stylianopoulos T, Papageorgis P.

Front Oncol. 2019 Feb 5;9:32. doi: 10.3389/fonc.2019.00032. eCollection 2019.


Molecular Mechanisms and Emerging Therapeutic Targets of Triple-Negative Breast Cancer Metastasis.

Neophytou C, Boutsikos P, Papageorgis P.

Front Oncol. 2018 Feb 22;8:31. doi: 10.3389/fonc.2018.00031. eCollection 2018. Review.


Solid Stress Facilitates Fibroblasts Activation to Promote Pancreatic Cancer Cell Migration.

Kalli M, Papageorgis P, Gkretsi V, Stylianopoulos T.

Ann Biomed Eng. 2018 May;46(5):657-669. doi: 10.1007/s10439-018-1997-7. Epub 2018 Feb 22.


Sonic-hedgehog pathway inhibition normalizes desmoplastic tumor microenvironment to improve chemo- and nanotherapy.

Mpekris F, Papageorgis P, Polydorou C, Voutouri C, Kalli M, Pirentis AP, Stylianopoulos T.

J Control Release. 2017 Sep 10;261:105-112. doi: 10.1016/j.jconrel.2017.06.022. Epub 2017 Jun 27.


Pirfenidone normalizes the tumor microenvironment to improve chemotherapy.

Polydorou C, Mpekris F, Papageorgis P, Voutouri C, Stylianopoulos T.

Oncotarget. 2017 Apr 11;8(15):24506-24517. doi: 10.18632/oncotarget.15534.


Tranilast-induced stress alleviation in solid tumors improves the efficacy of chemo- and nanotherapeutics in a size-independent manner.

Papageorgis P, Polydorou C, Mpekris F, Voutouri C, Agathokleous E, Kapnissi-Christodoulou CP, Stylianopoulos T.

Sci Rep. 2017 Apr 10;7:46140. doi: 10.1038/srep46140.


The concept of ageing in evolutionary algorithms: Discussion and inspirations for human ageing.

Dimopoulos C, Papageorgis P, Boustras G, Efstathiades C.

Mech Ageing Dev. 2017 Apr;163:8-14. doi: 10.1016/j.mad.2017.02.002. Epub 2017 Feb 4.


Complex Interplay Between Aging and Cancer: Role of TGF-β Signaling.

Papageorgis P.

Crit Rev Oncog. 2017;22(3-4):313-321. doi: 10.1615/CritRevOncog.2017025134. Review.


Hyaluronan-Derived Swelling of Solid Tumors, the Contribution of Collagen and Cancer Cells, and Implications for Cancer Therapy.

Voutouri C, Polydorou C, Papageorgis P, Gkretsi V, Stylianopoulos T.

Neoplasia. 2016 Dec;18(12):732-741. doi: 10.1016/j.neo.2016.10.001. Epub 2016 Nov 22.


SDPR functions as a metastasis suppressor in breast cancer by promoting apoptosis.

Ozturk S, Papageorgis P, Wong CK, Lambert AW, Abdolmaleky HM, Thiagalingam A, Cohen HT, Thiagalingam S.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):638-43. doi: 10.1073/pnas.1514663113. Epub 2016 Jan 6.


Multiscale modelling of solid tumour growth: the effect of collagen micromechanics.

Wijeratne PA, Vavourakis V, Hipwell JH, Voutouri C, Papageorgis P, Stylianopoulos T, Evans A, Hawkes DJ.

Biomech Model Mechanobiol. 2016 Oct;15(5):1079-90. doi: 10.1007/s10237-015-0745-2. Epub 2015 Nov 12.


Remodeling Components of the Tumor Microenvironment to Enhance Cancer Therapy.

Gkretsi V, Stylianou A, Papageorgis P, Polydorou C, Stylianopoulos T.

Front Oncol. 2015 Oct 14;5:214. doi: 10.3389/fonc.2015.00214. eCollection 2015. Review.


Tumor Cell-Derived Periostin Regulates Cytokines That Maintain Breast Cancer Stem Cells.

Lambert AW, Wong CK, Ozturk S, Papageorgis P, Raghunathan R, Alekseyev Y, Gower AC, Reinhard BM, Abdolmaleky HM, Thiagalingam S.

Mol Cancer Res. 2016 Jan;14(1):103-13. doi: 10.1158/1541-7786.MCR-15-0079. Epub 2015 Oct 27.


Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis.

Papageorgis P, Ozturk S, Lambert AW, Neophytou CM, Tzatsos A, Wong CK, Thiagalingam S, Constantinou AI.

Breast Cancer Res. 2015 Jul 25;17:98. doi: 10.1186/s13058-015-0607-y.


Remodeling of extracellular matrix due to solid stress accumulation during tumor growth.

Pirentis AP, Polydorou C, Papageorgis P, Voutouri C, Mpekris F, Stylianopoulos T.

Connect Tissue Res. 2015;56(5):345-54. doi: 10.3109/03008207.2015.1047929. Epub 2015 Jul 21.


TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis.

Papageorgis P.

J Oncol. 2015;2015:587193. doi: 10.1155/2015/587193. Epub 2015 Mar 25. Review.


Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review).

Papageorgis P, Stylianopoulos T.

Int J Oncol. 2015 Mar;46(3):933-43. doi: 10.3892/ijo.2015.2816. Epub 2015 Jan 7. Review.


Role of constitutive behavior and tumor-host mechanical interactions in the state of stress and growth of solid tumors.

Voutouri C, Mpekris F, Papageorgis P, Odysseos AD, Stylianopoulos T.

PLoS One. 2014 Aug 11;9(8):e104717. doi: 10.1371/journal.pone.0104717. eCollection 2014.


D-alpha-tocopheryl polyethylene glycol succinate (TPGS) induces cell cycle arrest and apoptosis selectively in Survivin-overexpressing breast cancer cells.

Neophytou CM, Constantinou C, Papageorgis P, Constantinou AI.

Biochem Pharmacol. 2014 May 1;89(1):31-42. doi: 10.1016/j.bcp.2014.02.003. Epub 2014 Feb 20.


Reversal of ER-β silencing by chromatin modifying agents overrides acquired tamoxifen resistance.

Pitta CA, Papageorgis P, Charalambous C, Constantinou AI.

Cancer Lett. 2013 Sep 1;337(2):167-76. doi: 10.1016/j.canlet.2013.05.031. Epub 2013 Jun 7.


Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder.

Abdolmaleky HM, Yaqubi S, Papageorgis P, Lambert AW, Ozturk S, Sivaraman V, Thiagalingam S.

Schizophr Res. 2011 Jul;129(2-3):183-90. doi: 10.1016/j.schres.2011.04.007. Epub 2011 May 7.


Smad4 inactivation promotes malignancy and drug resistance of colon cancer.

Papageorgis P, Cheng K, Ozturk S, Gong Y, Lambert AW, Abdolmaleky HM, Zhou JR, Thiagalingam S.

Cancer Res. 2011 Feb 1;71(3):998-1008. doi: 10.1158/0008-5472.CAN-09-3269. Epub 2011 Jan 18.


Smad signaling is required to maintain epigenetic silencing during breast cancer progression.

Papageorgis P, Lambert AW, Ozturk S, Gao F, Pan H, Manne U, Alekseyev YO, Thiagalingam A, Abdolmaleky HM, Lenburg M, Thiagalingam S.

Cancer Res. 2010 Feb 1;70(3):968-78. doi: 10.1158/0008-5472.CAN-09-1872. Epub 2010 Jan 19.


hBub1 negatively regulates p53 mediated early cell death upon mitotic checkpoint activation.

Gao F, Ponte JF, Levy M, Papageorgis P, Cook NM, Ozturk S, Lambert AW, Thiagalingam A, Abdolmaleky HM, Sullivan BA, Thiagalingam S.

Cancer Biol Ther. 2009 Apr;8(7):548-56. Epub 2009 Apr 22.


hBub1 deficiency triggers a novel p53 mediated early apoptotic checkpoint pathway in mitotic spindle damaged cells.

Gao F, Ponte JF, Papageorgis P, Levy M, Ozturk S, Lambert AW, Pan H, Chinnappan D, Cheng KH, Thiagalingam A, Abdolmaleky HM, Thiagalingam S.

Cancer Biol Ther. 2009 Apr;8(7):627-35. Epub 2009 Apr 22.


Aberrant activation of gamma-catenin promotes genomic instability and oncogenic effects during tumor progression.

Pan H, Gao F, Papageorgis P, Abdolmaleky HM, Faller DV, Thiagalingam S.

Cancer Biol Ther. 2007 Oct;6(10):1638-43. Epub 2007 Aug 17.


Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder.

Abdolmaleky HM, Cheng KH, Faraone SV, Wilcox M, Glatt SJ, Gao F, Smith CL, Shafa R, Aeali B, Carnevale J, Pan H, Papageorgis P, Ponte JF, Sivaraman V, Tsuang MT, Thiagalingam S.

Hum Mol Genet. 2006 Nov 1;15(21):3132-45. Epub 2006 Sep 19.

Supplemental Content

Loading ...
Support Center