Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 128


Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania.

Bhattacharya A, Leprohon P, Bigot S, Padmanabhan PK, Mukherjee A, Roy G, Gingras H, Mestdagh A, Papadopoulou B, Ouellette M.

Nat Commun. 2019 Dec 9;10(1):5627. doi: 10.1038/s41467-019-13344-6.


Valosin-containing protein VCP/p97 is essential for the intracellular development of Leishmania and its survival under heat stress.

Guedes Aguiar B, Padmanabhan PK, Dumas C, Papadopoulou B.

Cell Microbiol. 2018 Oct;20(10):e12867. doi: 10.1111/cmi.12867. Epub 2018 Jun 28.


Phosphorylation and interactions associated with the control of the Leishmania Poly-A Binding Protein 1 (PABP1) function during translation initiation.

de Melo Neto OP, da Costa Lima TDC, Merlo KC, Romão TP, Rocha PO, Assis LA, Nascimento LM, Xavier CC, Rezende AM, Reis CRS, Papadopoulou B.

RNA Biol. 2018;15(6):739-755. doi: 10.1080/15476286.2018.1445958. Epub 2018 Mar 23.


Drug resistance and treatment failure in leishmaniasis: A 21st century challenge.

Ponte-Sucre A, Gamarro F, Dujardin JC, Barrett MP, López-Vélez R, García-Hernández R, Pountain AW, Mwenechanya R, Papadopoulou B.

PLoS Negl Trop Dis. 2017 Dec 14;11(12):e0006052. doi: 10.1371/journal.pntd.0006052. eCollection 2017 Dec. Review.


The Pumilio-domain protein PUF6 contributes to SIDER2 retroposon-mediated mRNA decay in Leishmania.

Azizi H, Dumas C, Papadopoulou B.

RNA. 2017 Dec;23(12):1874-1885. doi: 10.1261/rna.062950.117. Epub 2017 Sep 6.


RNA secondary structure and nucleotide composition of the conserved hallmark sequence of Leishmania SIDER2 retroposons are essential for endonucleolytic cleavage and mRNA degradation.

Azizi H, Romão TP, Santos Charret K, Padmanabhan PK, de Melo Neto OP, Müller-McNicoll M, Papadopoulou B.

PLoS One. 2017 Jul 13;12(7):e0180678. doi: 10.1371/journal.pone.0180678. eCollection 2017.


SIDER2 retroposon-mediated mRNA decay in Leishmania is coupled to translation.

Azizi H, Müller-McNicoll M, Papadopoulou B.

Int J Parasitol. 2017 May;47(6):305-310. doi: 10.1016/j.ijpara.2017.02.001. Epub 2017 Mar 14.


DDX3 DEAD-box RNA helicase plays a central role in mitochondrial protein quality control in Leishmania.

Padmanabhan PK, Zghidi-Abouzid O, Samant M, Dumas C, Aguiar BG, Estaquier J, Papadopoulou B.

Cell Death Dis. 2016 Oct 13;7(10):e2406. doi: 10.1038/cddis.2016.315.


Plasticity of the Leishmania genome leading to gene copy number variations and drug resistance.

Laffitte MN, Leprohon P, Papadopoulou B, Ouellette M.

F1000Res. 2016 Sep 20;5:2350. doi: 10.12688/f1000research.9218.1. eCollection 2016. Review.


Cos-Seq for high-throughput identification of drug target and resistance mechanisms in the protozoan parasite Leishmania.

Gazanion É, Fernández-Prada C, Papadopoulou B, Leprohon P, Ouellette M.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):E3012-21. doi: 10.1073/pnas.1520693113. Epub 2016 May 9.


The unique Leishmania EIF4E4 N-terminus is a target for multiple phosphorylation events and participates in critical interactions required for translation initiation.

de Melo Neto OP, da Costa Lima TD, Xavier CC, Nascimento LM, Romão TP, Assis LA, Pereira MM, Reis CR, Papadopoulou B.

RNA Biol. 2015;12(11):1209-21. doi: 10.1080/15476286.2015.1086865. Epub 2015 Sep 4.


Differential Subcellular Localization of Leishmania Alba-Domain Proteins throughout the Parasite Development.

Dupé A, Dumas C, Papadopoulou B.

PLoS One. 2015 Sep 3;10(9):e0137243. doi: 10.1371/journal.pone.0137243. eCollection 2015.


Leishmania tarentolae secreting the sand fly salivary antigen PpSP15 confers protection against Leishmania major infection in a susceptible BALB/c mice model.

Katebi A, Gholami E, Taheri T, Zahedifard F, Habibzadeh S, Taslimi Y, Shokri F, Papadopoulou B, Kamhawi S, Valenzuela JG, Rafati S.

Mol Immunol. 2015 Oct;67(2 Pt B):501-11. doi: 10.1016/j.molimm.2015.08.001. Epub 2015 Aug 19.


Immunological comparison of DNA vaccination using two delivery systems against canine leishmaniasis.

Shahbazi M, Zahedifard F, Saljoughian N, Doroud D, Jamshidi S, Mahdavi N, Shirian S, Daneshbod Y, Hamid Zarkesh-Esfahani S, Papadopoulou B, Rafati S.

Vet Parasitol. 2015 Sep 15;212(3-4):130-9. doi: 10.1016/j.vetpar.2015.07.005. Epub 2015 Jul 21.


Evaluation of Live Recombinant Nonpathogenic Leishmania tarentolae Expressing Cysteine Proteinase and A2 Genes as a Candidate Vaccine against Experimental Canine Visceral Leishmaniasis.

Shahbazi M, Zahedifard F, Taheri T, Taslimi Y, Jamshidi S, Shirian S, Mahdavi N, Hassankhani M, Daneshbod Y, Zarkesh-Esfahani SH, Papadopoulou B, Rafati S.

PLoS One. 2015 Jul 21;10(7):e0132794. doi: 10.1371/journal.pone.0132794. eCollection 2015. Retraction in: PLoS One. 2019 Jul 5;14(7):e0218050.


Contrast echocardiography detecting a rare abnormal venous connection.

Strachinaru M, Papadopoulou B, Damry N, Laureys M, Samyn S.

Eur Heart J Cardiovasc Imaging. 2015 Jul;16(7):813. doi: 10.1093/ehjci/jev062. Epub 2015 Mar 29. No abstract available.


Species-specific antimonial sensitivity in Leishmania is driven by post-transcriptional regulation of AQP1.

Mandal G, Mandal S, Sharma M, Charret KS, Papadopoulou B, Bhattacharjee H, Mukhopadhyay R.

PLoS Negl Trop Dis. 2015 Feb 25;9(2):e0003500. doi: 10.1371/journal.pntd.0003500. eCollection 2015 Feb.


Approaches for studying mRNA decay mediated by SIDER2 retroposons in Leishmania.

Papadopoulou B, Müller-McNicoll M, Padmanabhan PK.

Methods Mol Biol. 2015;1201:123-42. doi: 10.1007/978-1-4939-1438-8_7.


Altered expression of an RBP-associated arginine methyltransferase 7 in Leishmania major affects parasite infection.

Ferreira TR, Alves-Ferreira EV, Defina TP, Walrad P, Papadopoulou B, Cruz AK.

Mol Microbiol. 2014 Oct 8. doi: 10.1111/mmi.12819. [Epub ahead of print]


Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines.

Ann J, Samant M, Rheaume C, Dumas C, Beaulieu E, Morasse A, Mallett C, Hamelin ME, Papadopoulou B, Boivin G.

Vaccine. 2014 Sep 29;32(43):5730-9. doi: 10.1016/j.vaccine.2014.08.029. Epub 2014 Aug 27.


Genome-wide stochastic adaptive DNA amplification at direct and inverted DNA repeats in the parasite Leishmania.

Ubeda JM, Raymond F, Mukherjee A, Plourde M, Gingras H, Roy G, Lapointe A, Leprohon P, Papadopoulou B, Corbeil J, Ouellette M.

PLoS Biol. 2014 May 20;12(5):e1001868. doi: 10.1371/journal.pbio.1001868. eCollection 2014 May.


Enhanced protective efficacy of nonpathogenic recombinant leishmania tarentolae expressing cysteine proteinases combined with a sand fly salivary antigen.

Zahedifard F, Gholami E, Taheri T, Taslimi Y, Doustdari F, Seyed N, Torkashvand F, Meneses C, Papadopoulou B, Kamhawi S, Valenzuela JG, Rafati S.

PLoS Negl Trop Dis. 2014 Mar 27;8(3):e2751. doi: 10.1371/journal.pntd.0002751. eCollection 2014 Mar.


An Alba-domain protein contributes to the stage-regulated stability of amastin transcripts in Leishmania.

Dupé A, Dumas C, Papadopoulou B.

Mol Microbiol. 2014 Feb;91(3):548-61. doi: 10.1111/mmi.12478. Epub 2013 Dec 19.


Cationic solid-lipid nanoparticles are as efficient as electroporation in DNA vaccination against visceral leishmaniasis in mice.

Saljoughian N, Zahedifard F, Doroud D, Doustdari F, Vasei M, Papadopoulou B, Rafati S.

Parasite Immunol. 2013 Dec;35(12):397-408. doi: 10.1111/pim.12042.


Development of novel prime-boost strategies based on a tri-gene fusion recombinant L. tarentolae vaccine against experimental murine visceral leishmaniasis.

Saljoughian N, Taheri T, Zahedifard F, Taslimi Y, Doustdari F, Bolhassani A, Doroud D, Azizi H, Heidari K, Vasei M, Namvar Asl N, Papadopoulou B, Rafati S.

PLoS Negl Trop Dis. 2013 Apr 18;7(4):e2174. doi: 10.1371/journal.pntd.0002174. Print 2013.


Novel features of a PIWI-like protein homolog in the parasitic protozoan Leishmania.

Padmanabhan PK, Dumas C, Samant M, Rochette A, Simard MJ, Papadopoulou B.

PLoS One. 2012;7(12):e52612. doi: 10.1371/journal.pone.0052612. Epub 2012 Dec 21.


Apoptosis-like programmed cell death induces antisense ribosomal RNA (rRNA) fragmentation and rRNA degradation in Leishmania.

Padmanabhan PK, Samant M, Cloutier S, Simard MJ, Papadopoulou B.

Cell Death Differ. 2012 Dec;19(12):1972-82. doi: 10.1038/cdd.2012.85. Epub 2012 Jul 6.


Analysis of membrane-enriched and high molecular weight proteins in Leishmania infantum promastigotes and axenic amastigotes.

Brotherton MC, Racine G, Ouameur AA, Leprohon P, Papadopoulou B, Ouellette M.

J Proteome Res. 2012 Aug 3;11(8):3974-85. doi: 10.1021/pr201248h. Epub 2012 Jul 10.


Translational control through eIF2alpha phosphorylation during the Leishmania differentiation process.

Cloutier S, Laverdière M, Chou MN, Boilard N, Chow C, Papadopoulou B.

PLoS One. 2012;7(5):e35085. doi: 10.1371/journal.pone.0035085. Epub 2012 May 31.


Effects of different adjuvants in the context of intramuscular and intranasal routes on humoral and cellular immune responses induced by detergent-split A/H3N2 influenza vaccines in mice.

Baz M, Samant M, Zekki H, Tribout-Jover P, Plante M, Lanteigne AM, Hamelin ME, Mallett C, Papadopoulou B, Boivin G.

Clin Vaccine Immunol. 2012 Feb;19(2):209-18. doi: 10.1128/CVI.05441-11. Epub 2011 Dec 21.


Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species.

Raymond F, Boisvert S, Roy G, Ritt JF, Légaré D, Isnard A, Stanke M, Olivier M, Tremblay MJ, Papadopoulou B, Ouellette M, Corbeil J.

Nucleic Acids Res. 2012 Feb;40(3):1131-47. doi: 10.1093/nar/gkr834. Epub 2011 Oct 13.


Akt determines cell fate through inhibition of the PERK-eIF2α phosphorylation pathway.

Mounir Z, Krishnamoorthy JL, Wang S, Papadopoulou B, Campbell S, Muller WJ, Hatzoglou M, Koromilas AE.

Sci Signal. 2011 Sep 27;4(192):ra62. doi: 10.1126/scisignal.2001630.


A late complication of percutaneous radial artery cannulation.

Nazeri A, Sohawon S, Papadopoulou B, Georgala A, Dernier Y, Noordally SO.

Acta Clin Belg. 2011 May-Jun;66(3):223-5.


Characterization of hibernating ribosomes in mammalian cells.

Krokowski D, Gaccioli F, Majumder M, Mullins MR, Yuan CL, Papadopoulou B, Merrick WC, Komar AA, Taylor D, Hatzoglou M.

Cell Cycle. 2011 Aug 15;10(16):2691-702. Epub 2011 Aug 15.


Promastigote to amastigote differentiation of Leishmania is markedly delayed in the absence of PERK eIF2alpha kinase-dependent eIF2alpha phosphorylation.

Chow C, Cloutier S, Dumas C, Chou MN, Papadopoulou B.

Cell Microbiol. 2011 Jul;13(7):1059-77. doi: 10.1111/j.1462-5822.2011.01602.x. Epub 2011 May 30.


Leishmania major: Protective capacity of DNA vaccine using amastin fused to HSV-1 VP22 and EGFP in BALB/c mice model.

Bolhassani A, Gholami E, Zahedifard F, Moradin N, Parsi P, Doustdari F, Seyed N, Papadopoulou B, Rafati S.

Exp Parasitol. 2011 May;128(1):9-17. doi: 10.1016/j.exppara.2011.01.012. Epub 2011 Jan 26.


Cell homeostasis in a Leishmania major mutant overexpressing the spliced leader RNA is maintained by an increased proteolytic activity.

Toledo JS, Ferreira TR, Defina TP, Dossin Fde M, Beattie KA, Lamont DJ, Cloutier S, Papadopoulou B, Schenkman S, Cruz AK.

Int J Biochem Cell Biol. 2010 Oct;42(10):1661-71. doi: 10.1016/j.biocel.2010.06.013. Epub 2010 Jun 22.


Analysis of stage-specific expression of basic proteins in Leishmania infantum.

Brotherton MC, Racine G, Foucher AL, Drummelsmith J, Papadopoulou B, Ouellette M.

J Proteome Res. 2010 Aug 6;9(8):3842-53. doi: 10.1021/pr100048m.


Selective inactivation of SIDER2 retroposon-mediated mRNA decay contributes to stage- and species-specific gene expression in Leishmania.

Müller M, Padmanabhan PK, Papadopoulou B.

Mol Microbiol. 2010 Jul;77(2):471-91. doi: 10.1111/j.1365-2958.2010.07226.x. Epub 2010 May 24.


Rapid decay of unstable Leishmania mRNAs bearing a conserved retroposon signature 3'-UTR motif is initiated by a site-specific endonucleolytic cleavage without prior deadenylation.

Müller M, Padmanabhan PK, Rochette A, Mukherjee D, Smith M, Dumas C, Papadopoulou B.

Nucleic Acids Res. 2010 Sep;38(17):5867-83. doi: 10.1093/nar/gkq349. Epub 2010 May 7.


Coordinated gene expression by post-transcriptional regulons in African trypanosomes.

Ouellette M, Papadopoulou B.

J Biol. 2009;8(11):100. doi: 10.1186/jbiol203. Epub 2009 Dec 14. Review.


Stage-specific expression of the glycine cleavage complex subunits in Leishmania infantum.

Müller M, Papadopoulou B.

Mol Biochem Parasitol. 2010 Mar;170(1):17-27. doi: 10.1016/j.molbiopara.2009.11.009. Epub 2009 Dec 2.


Analysis of ribosomal RNA transcription termination and 3' end processing in Leishmania amazonensis.

Abreu-Blanco MT, Ramírez JL, Pinto-Santini DM, Papadopoulou B, Guevara P.

Gene. 2010 Feb 1;451(1-2):15-22. doi: 10.1016/j.gene.2009.11.002. Epub 2009 Nov 12.


Recombinant Leishmania tarentolae expressing the A2 virulence gene as a novel candidate vaccine against visceral leishmaniasis.

Mizbani A, Taheri T, Zahedifard F, Taslimi Y, Azizi H, Azadmanesh K, Papadopoulou B, Rafati S.

Vaccine. 2009 Dec 10;28(1):53-62. doi: 10.1016/j.vaccine.2009.09.114. Epub 2009 Oct 8.


Organization and evolution of two SIDER retroposon subfamilies and their impact on the Leishmania genome.

Smith M, Bringaud F, Papadopoulou B.

BMC Genomics. 2009 May 22;10:240. doi: 10.1186/1471-2164-10-240.


Searching for virulence factors in the non-pathogenic parasite to humans Leishmania tarentolae.

Azizi H, Hassani K, Taslimi Y, Najafabadi HS, Papadopoulou B, Rafati S.

Parasitology. 2009 Jun;136(7):723-35. doi: 10.1017/S0031182009005873. Epub 2009 May 6.


Whole-genome comparative RNA expression profiling of axenic and intracellular amastigote forms of Leishmania infantum.

Rochette A, Raymond F, Corbeil J, Ouellette M, Papadopoulou B.

Mol Biochem Parasitol. 2009 May;165(1):32-47. doi: 10.1016/j.molbiopara.2008.12.012. Epub 2009 Jan 15.


Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy.

Ubeda JM, Légaré D, Raymond F, Ouameur AA, Boisvert S, Rigault P, Corbeil J, Tremblay MJ, Olivier M, Papadopoulou B, Ouellette M.

Genome Biol. 2008;9(7):R115. doi: 10.1186/gb-2008-9-7-r115. Epub 2008 Jul 18.


Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species.

Rochette A, Raymond F, Ubeda JM, Smith M, Messier N, Boisvert S, Rigault P, Corbeil J, Ouellette M, Papadopoulou B.

BMC Genomics. 2008 May 29;9:255. doi: 10.1186/1471-2164-9-255.


Role of transposable elements in trypanosomatids.

Bringaud F, Ghedin E, El-Sayed NM, Papadopoulou B.

Microbes Infect. 2008 May;10(6):575-81. doi: 10.1016/j.micinf.2008.02.009. Epub 2008 Feb 21. Review.


Supplemental Content

Loading ...
Support Center