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Management of a patient with heart failure by sacubitril/valsartan: improvement of functional capacity.

Paolini C, Perrone C, Pellizzari CA, Randon ML, Bilato C.

Curr Med Res Opin. 2019 Mar;35(sup1):7-8. doi: 10.1080/03007995.2019.1576482.


Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy.

Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin P, Baraibar MA, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M.

EMBO J. 2019 Jan 3;38(1). pii: e99576. doi: 10.15252/embj.201899576. Epub 2018 Nov 12.


Feasibility of robotic resection of gastrointestinal stromal tumors along the entire gastrointestinal tract.

Guerra F, Paolini C, Vegni A, Gasperoni S, Desiderio J, Parisi A, Coratti A.

Updates Surg. 2018 Jul 17. doi: 10.1007/s13304-018-0568-7. [Epub ahead of print]


Mesenchymal stromal cells from human umbilical cord prevent the development of lung fibrosis in immunocompetent mice.

Moroncini G, Paolini C, Orlando F, Capelli C, Grieco A, Tonnini C, Agarbati S, Mondini E, Saccomanno S, Goteri G, Svegliati Baroni S, Provinciali M, Introna M, Del Papa N, Gabrielli A.

PLoS One. 2018 Jun 1;13(6):e0196048. doi: 10.1371/journal.pone.0196048. eCollection 2018.


Strenuous exercise triggers a life-threatening response in mice susceptible to malignant hyperthermia.

Michelucci A, Paolini C, Boncompagni S, Canato M, Reggiani C, Protasi F.

FASEB J. 2017 Aug;31(8):3649-3662. doi: 10.1096/fj.201601292R. Epub 2017 May 2.


Characterization of binding and quantification of human autoantibodies to PDGFRα using a biosensor-based approach.

Moroncini G, Cuccioloni M, Mozzicafreddo M, Pozniak KN, Grieco A, Paolini C, Tonnini C, Spadoni T, Svegliati S, Funaro A, Angeletti M, Gabrielli A.

Anal Biochem. 2017 Jul 1;528:26-33. doi: 10.1016/j.ab.2017.04.011. Epub 2017 Apr 24.


Corrigendum: Agonistic Anti-PDGF Receptor Autoantibodies from Patients with Systemic Sclerosis Impact Human Pulmonary Artery Smooth Muscle Cells Function In Vitro.

Svegliati S, Amico D, Spadoni T, Fischetti C, Finke D, Moroncini G, Paolini C, Tonnini C, Grieco A, Rovinelli M, Funaro A, Gabrielli A.

Front Immunol. 2017 Apr 12;8:381. doi: 10.3389/fimmu.2017.00381. eCollection 2017.


Agonistic Anti-PDGF Receptor Autoantibodies from Patients with Systemic Sclerosis Impact Human Pulmonary Artery Smooth Muscle Cells Function In Vitro.

Svegliati S, Amico D, Spadoni T, Fischetti C, Finke D, Moroncini G, Paolini C, Tonnini C, Grieco A, Rovinelli M, Funaro A, Gabrielli A.

Front Immunol. 2017 Feb 8;8:75. doi: 10.3389/fimmu.2017.00075. eCollection 2017. Erratum in: Front Immunol. 2017 Apr 12;8:381.


Exercise-induced alterations and loss of sarcomeric M-line organization in the diaphragm muscle of obscurin knockout mice.

Randazzo D, Blaauw B, Paolini C, Pierantozzi E, Spinozzi S, Lange S, Chen J, Protasi F, Reggiani C, Sorrentino V.

Am J Physiol Cell Physiol. 2017 Jan 1;312(1):C16-C28. doi: 10.1152/ajpcell.00098.2016. Epub 2016 Oct 26.


Induction of Scleroderma Fibrosis in Skin-Humanized Mice by Administration of Anti-Platelet-Derived Growth Factor Receptor Agonistic Autoantibodies.

Luchetti MM, Moroncini G, Jose Escamez M, Svegliati Baroni S, Spadoni T, Grieco A, Paolini C, Funaro A, Avvedimento EV, Larcher F, Del Rio M, Gabrielli A.

Arthritis Rheumatol. 2016 Sep;68(9):2263-73. doi: 10.1002/art.39728.


Single vs double antiplatelet therapy in acute coronary syndrome: Predictors of bleeding after coronary artery bypass grafting.

Tarzia V, Bortolussi G, Buratto E, Paolini C, Dal Lin C, Rizzoli G, Bottio T, Gerosa G.

World J Cardiol. 2015 Sep 26;7(9):571-8. doi: 10.4330/wjc.v7.i9.571.


A CASQ1 founder mutation in three Italian families with protein aggregate myopathy and hyperCKaemia.

Di Blasi C, Sansanelli S, Ruggieri A, Moriggi M, Vasso M, D'Adamo AP, Blasevich F, Zanotti S, Paolini C, Protasi F, Tezzon F, Gelfi C, Morandi L, Pessia M, Mora M.

J Med Genet. 2015 Sep;52(9):617-26. doi: 10.1136/jmedgenet-2014-102882. Epub 2015 Jul 1.


Antioxidants protect calsequestrin-1 knockout mice from halothane- and heat-induced sudden death.

Michelucci A, Paolini C, Canato M, Wei-Lapierre L, Pietrangelo L, De Marco A, Reggiani C, Dirksen RT, Protasi F.

Anesthesiology. 2015 Sep;123(3):603-17. doi: 10.1097/ALN.0000000000000748.


Oxidative stress, mitochondrial damage, and cores in muscle from calsequestrin-1 knockout mice.

Paolini C, Quarta M, Wei-LaPierre L, Michelucci A, Nori A, Reggiani C, Dirksen RT, Protasi F.

Skelet Muscle. 2015 Apr 18;5:10. doi: 10.1186/s13395-015-0035-9. eCollection 2015.


Epitope Specificity Determines Pathogenicity and Detectability of Anti-Platelet-Derived Growth Factor Receptor α Autoantibodies in Systemic Sclerosis.

Moroncini G, Grieco A, Nacci G, Paolini C, Tonnini C, Pozniak KN, Cuccioloni M, Mozzicafreddo M, Svegliati S, Angeletti M, Kazlauskas A, Avvedimento EV, Funaro A, Gabrielli A.

Arthritis Rheumatol. 2015 Jul;67(7):1891-903. doi: 10.1002/art.39125.


Deletion of small ankyrin 1 (sAnk1) isoforms results in structural and functional alterations in aging skeletal muscle fibers.

Giacomello E, Quarta M, Paolini C, Squecco R, Fusco P, Toniolo L, Blaauw B, Formoso L, Rossi D, Birkenmeier C, Peters LL, Francini F, Protasi F, Reggiani C, Sorrentino V.

Am J Physiol Cell Physiol. 2015 Jan 15;308(2):C123-38. doi: 10.1152/ajpcell.00090.2014. Epub 2014 Oct 29.


Facilitating Lewin's change model with collaborative evaluation in promoting evidence based practices of health professionals.

Manchester J, Gray-Miceli DL, Metcalf JA, Paolini CA, Napier AH, Coogle CL, Owens MG.

Eval Program Plann. 2014 Dec;47:82-90. doi: 10.1016/j.evalprogplan.2014.08.007. Epub 2014 Aug 23.


A mutation in the CASQ1 gene causes a vacuolar myopathy with accumulation of sarcoplasmic reticulum protein aggregates.

Rossi D, Vezzani B, Galli L, Paolini C, Toniolo L, Pierantozzi E, Spinozzi S, Barone V, Pegoraro E, Bello L, Cenacchi G, Vattemi G, Tomelleri G, Ricci G, Siciliano G, Protasi F, Reggiani C, Sorrentino V.

Hum Mutat. 2014 Oct;35(10):1163-70. doi: 10.1002/humu.22631. Epub 2014 Sep 10.


The danger of using a sledgehammer to crack a nut: ROTEM-guided administration of recombinant activated factor VII in a patient with refractory bleeding post-ventricular assist device implantation.

Tarzia V, Buratto E, Bortolussi G, Paolini C, Bejko J, Bottio T, Gerosa G.

Artif Organs. 2015 Mar;39(3):248-53. doi: 10.1111/aor.12355. Epub 2014 Jul 28. Review.


Distinct regions of triadin are required for targeting and retention at the junctional domain of the sarcoplasmic reticulum.

Rossi D, Bencini C, Maritati M, Benini F, Lorenzini S, Pierantozzi E, Scarcella AM, Paolini C, Protasi F, Sorrentino V.

Biochem J. 2014 Mar 1;458(2):407-17. doi: 10.1042/BJ20130719.


Mitochondrial Ca2+-handling in fast skeletal muscle fibers from wild type and calsequestrin-null mice.

Scorzeto M, Giacomello M, Toniolo L, Canato M, Blaauw B, Paolini C, Protasi F, Reggiani C, Stienen GJ.

PLoS One. 2013 Oct 3;8(10):e74919. doi: 10.1371/journal.pone.0074919. eCollection 2013.


[Screening for symptoms of depression during postpartum and the long term follow up: temporal stability and associated factors].

Rozic PR, Schvartzman JA, Paolini CI, Gadow A, Calvo DA, Paesani F, Pieczanski P, Vázquez GH, Lolich M, Krupitzki HB.

Vertex. 2012 Nov-Dec;23(106):409-17. Spanish.


Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease.

Nemazanyy I, Blaauw B, Paolini C, Caillaud C, Protasi F, Mueller A, Proikas-Cezanne T, Russell RC, Guan KL, Nishino I, Sandri M, Pende M, Panasyuk G.

EMBO Mol Med. 2013 Jun;5(6):870-90. doi: 10.1002/emmm.201202057. Epub 2013 Apr 30.


Enhanced dihydropyridine receptor calcium channel activity restores muscle strength in JP45/CASQ1 double knockout mice.

Mosca B, Delbono O, Laura Messi M, Bergamelli L, Wang ZM, Vukcevic M, Lopez R, Treves S, Nishi M, Takeshima H, Paolini C, Martini M, Rispoli G, Protasi F, Zorzato F.

Nat Commun. 2013;4:1541. doi: 10.1038/ncomms2496.


Skin equivalents: a tool for the discovery and validation of pharmacodynamic biomarkers.

Paolini C, Orecchia A, Failla CM, Gallinari P, Zambruno G, Steinkühler C.

Cancer Invest. 2013 Jan;31(1):60-6. doi: 10.3109/07357907.2012.749269.


Growth associated protein 43 is expressed in skeletal muscle fibers and is localized in proximity of mitochondria and calcium release units.

Guarnieri S, Morabito C, Paolini C, Boncompagni S, Pilla R, Fanò-Illic G, Mariggiò MA.

PLoS One. 2013;8(1):e53267. doi: 10.1371/journal.pone.0053267. Epub 2013 Jan 7.


Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells.

Rotili D, Tarantino D, Nebbioso A, Paolini C, Huidobro C, Lara E, Mellini P, Lenoci A, Pezzi R, Botta G, Lahtela-Kakkonen M, Poso A, Steinkühler C, Gallinari P, De Maria R, Fraga M, Esteller M, Altucci L, Mai A.

J Med Chem. 2012 Dec 27;55(24):10937-47. doi: 10.1021/jm3011614. Epub 2012 Dec 12.


Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells.

Rotili D, Tarantino D, Carafa V, Paolini C, Schemies J, Jung M, Botta G, Di Maro S, Novellino E, Steinkühler C, De Maria R, Gallinari P, Altucci L, Mai A.

J Med Chem. 2012 Sep 27;55(18):8193-7. Epub 2012 Sep 7.


Transplacental supply of mannose and inositol in uncomplicated pregnancies using stable isotopes.

Staat BC, Galan HL, Harwood JE, Lee G, Marconi AM, Paolini CL, Cheung A, Battaglia FC.

J Clin Endocrinol Metab. 2012 Jul;97(7):2497-502. doi: 10.1210/jc.2011-1800. Epub 2012 Apr 27.


Lessons from calsequestrin-1 ablation in vivo: much more than a Ca(2+) buffer after all.

Protasi F, Paolini C, Canato M, Reggiani C, Quarta M.

J Muscle Res Cell Motil. 2011 Dec;32(4-5):257-70. doi: 10.1007/s10974-011-9277-2. Epub 2011 Dec 1.


Calsequestrin (CASQ1) rescues function and structure of calcium release units in skeletal muscles of CASQ1-null mice.

Tomasi M, Canato M, Paolini C, Dainese M, Reggiani C, Volpe P, Protasi F, Nori A.

Am J Physiol Cell Physiol. 2012 Feb 1;302(3):C575-86. doi: 10.1152/ajpcell.00119.2011. Epub 2011 Nov 2.


Potential antibacterial activity of carvacrol-loaded poly(DL-lactide-co-glycolide) (PLGA) nanoparticles against microbial biofilm.

Iannitelli A, Grande R, Di Stefano A, Di Giulio M, Sozio P, Bessa LJ, Laserra S, Paolini C, Protasi F, Cellini L.

Int J Mol Sci. 2011;12(8):5039-51. doi: 10.3390/ijms12085039. Epub 2011 Aug 8.


Differential effect of calsequestrin ablation on structure and function of fast and slow skeletal muscle fibers.

Paolini C, Quarta M, D'Onofrio L, Reggiani C, Protasi F.

J Biomed Biotechnol. 2011;2011:634075. doi: 10.1155/2011/634075. Epub 2011 Sep 14.


Proteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasis.

Fortugno P, Bresciani A, Paolini C, Pazzagli C, El Hachem M, D'Alessio M, Zambruno G.

J Invest Dermatol. 2011 Nov;131(11):2223-32. doi: 10.1038/jid.2011.174. Epub 2011 Jun 23.


Home-based functional electrical stimulation rescues permanently denervated muscles in paraplegic patients with complete lower motor neuron lesion.

Kern H, Carraro U, Adami N, Biral D, Hofer C, Forstner C, Mödlin M, Vogelauer M, Pond A, Boncompagni S, Paolini C, Mayr W, Protasi F, Zampieri S.

Neurorehabil Neural Repair. 2010 Oct;24(8):709-21. doi: 10.1177/1545968310366129. Epub 2010 May 11.


Calsequestrin-1: a new candidate gene for malignant hyperthermia and exertional/environmental heat stroke.

Protasi F, Paolini C, Dainese M.

J Physiol. 2009 Jul 1;587(Pt 13):3095-100. doi: 10.1113/jphysiol.2009.171967. Epub 2009 May 5. Review.


Prenatal screening for chromosome abnormalities in a region with no access to termination of pregnancy.

Paolini CI, Gadow A, Petracchi F, Igarzabal L, Quadrelli R, Gadow EC.

Prenat Diagn. 2009 Jul;29(7):659-63. doi: 10.1002/pd.2270.


Anesthetic- and heat-induced sudden death in calsequestrin-1-knockout mice.

Dainese M, Quarta M, Lyfenko AD, Paolini C, Canato M, Reggiani C, Dirksen RT, Protasi F.

FASEB J. 2009 Jun;23(6):1710-20. doi: 10.1096/fj.08-121335. Epub 2009 Feb 23.


The transplacental transport of essential amino acids in uncomplicated human pregnancies.

Galan HL, Marconi AM, Paolini CL, Cheung A, Battaglia FC.

Am J Obstet Gynecol. 2009 Jan;200(1):91.e1-7. doi: 10.1016/j.ajog.2008.06.054. Epub 2008 Nov 18.


A web service infrastructure for thermochemical data.

Paolini CP, Bhattacharjee S.

J Chem Inf Model. 2008 Jul;48(7):1511-23. doi: 10.1021/ci700457p. Epub 2008 Jun 11.


Nutrient transport across the intrauterine growth-restricted placenta.

Marconi AM, Paolini CL.

Semin Perinatol. 2008 Jun;32(3):178-81. doi: 10.1053/j.semperi.2008.02.007. Review.


Alternative splicing of platelet cyclooxygenase-2 mRNA in patients after coronary artery bypass grafting.

Censarek P, Steger G, Paolini C, Hohlfeld T, Grosser T, Zimmermann N, Fleckenstein D, Schrör K, Weber AA.

Thromb Haemost. 2007 Dec;98(6):1309-15.


Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases.

Lahm A, Paolini C, Pallaoro M, Nardi MC, Jones P, Neddermann P, Sambucini S, Bottomley MJ, Lo Surdo P, Carfí A, Koch U, De Francesco R, Steinkühler C, Gallinari P.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17335-40. Epub 2007 Oct 23.


Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1.

Paolini C, Quarta M, Nori A, Boncompagni S, Canato M, Volpe P, Allen PD, Reggiani C, Protasi F.

J Physiol. 2007 Sep 1;583(Pt 2):767-84. Epub 2007 Jul 12.


Increased Ca2+ storage capacity of the skeletal muscle sarcoplasmic reticulum of transgenic mice over-expressing membrane bound calcium binding protein junctate.

Divet A, Paesante S, Grasso C, Cavagna D, Tiveron C, Paolini C, Protasi F, Huchet-Cadiou C, Treves S, Zorzato F.

J Cell Physiol. 2007 Nov;213(2):464-74.


Molecular insights into azumamide e histone deacetylases inhibitory activity.

Maulucci N, Chini MG, Micco SD, Izzo I, Cafaro E, Russo A, Gallinari P, Paolini C, Nardi MC, Casapullo A, Riccio R, Bifulco G, Riccardis FD.

J Am Chem Soc. 2007 Mar 14;129(10):3007-12. Epub 2007 Feb 21.


A structure-guided approach to an orthogonal estrogen-receptor-based gene switch activated by ligands suitable for in vivo studies.

Kinzel O, Fattori D, Muraglia E, Gallinari P, Nardi MC, Paolini C, Roscilli G, Toniatti C, Gonzalez Paz O, Laufer R, Lahm A, Tramontano A, Cortese R, De Francesco R, Ciliberto G, Koch U.

J Med Chem. 2006 Sep 7;49(18):5404-7.


Fetal and maternal non-glucose carbohydrates and polyols concentrations in normal human pregnancies at term.

Brusati V, Józwik M, Józwik M, Teng C, Paolini C, Marconi AM, Battaglia FC.

Pediatr Res. 2005 Oct;58(4):700-4.


A functionally orthogonal estrogen receptor-based transcription switch specifically induced by a nonsteroid synthetic ligand.

Gallinari P, Lahm A, Koch U, Paolini C, Nardi MC, Roscilli G, Kinzel O, Fattori D, Muraglia E, Toniatti C, Cortese R, De Francesco R, Ciliberto G.

Chem Biol. 2005 Aug;12(8):883-93.

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