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Reducing opioid usage: a pilot study comparing postoperative selective dorsal rhizotomy protocols.

Pao LP, Zhu L, Tariq S, Hill CA, Yu B, Kendrick M, Jungman M, Miesner EL, Mundluru SN, Hall SL, Bosques G, Thakur N, Shah MN.

J Neurosurg Pediatr. 2019 Nov 22:1-6. doi: 10.3171/2019.9.PEDS19398. [Epub ahead of print]


Grand challenges in the science of wind energy.

Veers P, Dykes K, Lantz E, Barth S, Bottasso CL, Carlson O, Clifton A, Green J, Green P, Holttinen H, Laird D, Lehtomäki V, Lundquist JK, Manwell J, Marquis M, Meneveau C, Moriarty P, Munduate X, Muskulus M, Naughton J, Pao L, Paquette J, Peinke J, Robertson A, Sanz Rodrigo J, Sempreviva AM, Smith JC, Tuohy A, Wiser R.

Science. 2019 Oct 25;366(6464). pii: eaau2027. doi: 10.1126/science.aau2027. Epub 2019 Oct 10. Review.


Long Non-coding RNA MEG3 Attenuates the Angiotensin II-Induced Injury of Human Umbilical Vein Endothelial Cells by Interacting With p53.

Song J, Huang S, Wang K, Li W, Pao L, Chen F, Zhao X.

Front Genet. 2019 Feb 19;10:78. doi: 10.3389/fgene.2019.00078. eCollection 2019.


Role of resting state MRI temporal latency in refractory pediatric extratemporal epilepsy lateralization.

Shah MN, Nguyen RD, Pao LP, Zhu L, CreveCoeur TS, Mitra A, Smyth MD.

J Magn Reson Imaging. 2019 May;49(5):1347-1355. doi: 10.1002/jmri.26320. Epub 2018 Oct 22.


Effects of processing adjuvants on traditional Chinese herbs.

Chen LL, Verpoorte R, Yen HR, Peng WH, Cheng YC, Chao J, Pao LH.

J Food Drug Anal. 2018 Apr;26(2S):S96-S114. doi: 10.1016/j.jfda.2018.02.004. Epub 2018 Mar 19. Review.


Major achievements of evidence-based traditional Chinese medicine in treating major diseases.

Chao J, Dai Y, Verpoorte R, Lam W, Cheng YC, Pao LH, Zhang W, Chen S.

Biochem Pharmacol. 2017 Sep 1;139:94-104. doi: 10.1016/j.bcp.2017.06.123. Epub 2017 Jun 19. Review.


The evolving relationship between adiponectin and insulin sensitivity in hepatitis C patients during viral clearance.

Chang ML, Kuo CJ, Pao LH, Hsu CM, Chiu CT.

Virulence. 2017 Oct 3;8(7):1255-1264. doi: 10.1080/21505594.2017.1300734. Epub 2017 Mar 7.


Link between plasminogen activator inhibitor-1 and cardiovascular risk in chronic hepatitis C after viral clearance.

Chang ML, Lin YS, Pao LH, Huang HC, Chiu CT.

Sci Rep. 2017 Feb 13;7:42503. doi: 10.1038/srep42503.


Verbal-spatial IQ discrepancies impact brain activation associated with the resolution of cognitive conflict in children and adolescents.

Margolis AE, Davis KS, Pao LS, Lewis A, Yang X, Tau G, Zhao G, Wang Z, Marsh R.

Dev Sci. 2018 Mar;21(2). doi: 10.1111/desc.12550. Epub 2017 Feb 15.


Improving the Concentrations of the Active Components in the Herbal Tea Ingredient, Uraria crinita: The Effect of Post-harvest Oven-drying Processing.

Chao J, Dai Y, Cheng HY, Lam W, Cheng YC, Li K, Peng WH, Pao LH, Hsieh MT, Qin XM, Lee MS.

Sci Rep. 2017 Jan 12;7:38763. doi: 10.1038/srep38763.


Synthesis and characterization of pH-responsive nanoscale hydrogels for oral delivery of hydrophobic therapeutics.

Puranik AS, Pao LP, White VM, Peppas NA.

Eur J Pharm Biopharm. 2016 Nov;108:196-213. doi: 10.1016/j.ejpb.2016.09.007. Epub 2016 Sep 12.


Pentoxifylline ameliorates non-alcoholic fatty liver disease in hyperglycaemic and dyslipidaemic mice by upregulating fatty acid β-oxidation.

Ye JH, Chao J, Chang ML, Peng WH, Cheng HY, Liao JW, Pao LH.

Sci Rep. 2016 Sep 9;6:33102. doi: 10.1038/srep33102.


Chinese herbal medicines promote hippocampal neuroproliferation, reduce stress hormone levels, inhibit apoptosis, and improve behavior in chronically stressed mice.

Sun GG, Shih JH, Chiou SH, Hong CJ, Lu SW, Pao LH.

J Ethnopharmacol. 2016 Dec 4;193:159-168. doi: 10.1016/j.jep.2016.07.025. Epub 2016 Jul 11.


Evaluation of brain SERT occupancy by resveratrol against MDMA-induced neurobiological and behavioral changes in rats: A 4-[¹⁸F]-ADAM/small-animal PET study.

Shih JH, Ma KH, Chen CF, Cheng CY, Pao LH, Weng SJ, Huang YS, Shiue CY, Yeh MK, Li IH.

Eur Neuropsychopharmacol. 2016 Jan;26(1):92-104. doi: 10.1016/j.euroneuro.2015.11.001. Epub 2015 Nov 14.


Blockade of KCa3.1 potassium channels protects against cisplatin-induced acute kidney injury.

Chen CL, Liao JW, Hu OY, Pao LH.

Arch Toxicol. 2016 Sep;90(9):2249-2260. doi: 10.1007/s00204-015-1607-5. Epub 2015 Oct 5.


Using Visualized Matrix Effects to Develop and Improve LC-MS/MS Bioanalytical Methods, Taking TRAM-34 as an Example.

Ye JH, Pao LH.

PLoS One. 2015 Apr 24;10(4):e0118818. doi: 10.1371/journal.pone.0118818. eCollection 2015.


Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome.

Zhang H, Pao LI, Zhou A, Brace AD, Halenbeck R, Hsu AW, Bray TL, Hestir K, Bosch E, Lee E, Wang G, Liu H, Wong BR, Kavanaugh WM, Williams LT.

Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15741-5. doi: 10.1073/pnas.1412009111. Epub 2014 Oct 20.


Gallic acid ameliorated impaired glucose and lipid homeostasis in high fat diet-induced NAFLD mice.

Chao J, Huo TI, Cheng HY, Tsai JC, Liao JW, Lee MS, Qin XM, Hsieh MT, Pao LH, Peng WH.

PLoS One. 2014 Jun 11;9(2):e96969. doi: 10.1371/journal.pone.0096969. eCollection 2014.


Dynamics modeling for parallel haptic interfaces with force sensing and control.

Bernstein N, Lawrence D, Pao L.

IEEE Trans Haptics. 2013 Oct-Dec;6(4):429-39. doi: 10.1109/TOH.2013.3.


Dietary flavonoids modulate CYP2C to improve drug oral bioavailability and their qualitative/quantitative structure-activity relationship.

Wang HJ, Pao LH, Hsiong CH, Shih TY, Lee MS, Hu OY.

AAPS J. 2014 Mar;16(2):258-68. doi: 10.1208/s12248-013-9549-4. Epub 2014 Jan 16.


Shp1 regulates T cell homeostasis by limiting IL-4 signals.

Johnson DJ, Pao LI, Dhanji S, Murakami K, Ohashi PS, Neel BG.

J Exp Med. 2013 Jul 1;210(7):1419-31.


Validated liquid chromatography-tandem mass spectrometry method for determination of totally nine probe metabolites of cytochrome P450 enzymes and UDP-glucuronosyltransferases.

Lee JT, Pao LH, Hsiong CH, Huang PW, Shih TY, Yoa-Pu Hu O.

Talanta. 2013 Mar 15;106:220-8. doi: 10.1016/j.talanta.2012.12.023. Epub 2012 Dec 22.


Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice.

Abram CL, Roberge GL, Pao LI, Neel BG, Lowell CA.

Immunity. 2013 Mar 21;38(3):489-501. doi: 10.1016/j.immuni.2013.02.018.


Antioxidant, Analgesic, Anti-Inflammatory, and Hepatoprotective Effects of the Ethanol Extract of Mahonia oiwakensis Stem.

Chao J, Liao JW, Peng WH, Lee MS, Pao LH, Cheng HY.

Int J Mol Sci. 2013 Jan 30;14(2):2928-45. doi: 10.3390/ijms14022928.


A new approach to facilitate diagnosis of nonalcoholic fatty liver disease through a galactose single point method in rats with fatty liver.

Lee JT, Pao LH, Lee MS, Liao JW, Shih CM, Hsiong CH, Yin FY, Shih TY, Hu OY.

Dig Liver Dis. 2013 Feb;45(2):134-41. doi: 10.1016/j.dld.2012.08.019. Epub 2012 Oct 1.


Three Chinese herbal medicines promote neuroproliferation in vitro, and reverse the effects of chronic mild stress on behavior, the HPA axis, and proliferation of hippocampal precursor cell in vivo.

Pao LH, Lu SW, Sun GG, Chiou SH, Ma KH.

J Ethnopharmacol. 2012 Nov 21;144(2):261-9. doi: 10.1016/j.jep.2012.09.002. Epub 2012 Sep 19.


Evaluation of chinese-herbal-medicine-induced herb-drug interactions: focusing on organic anion transporter 1.

Lin CC, Fan HY, Kuo CW, Pao LH.

Evid Based Complement Alternat Med. 2012;2012:967182. doi: 10.1155/2012/967182. Epub 2012 Sep 4.


Macrophages require Skap2 and Sirpα for integrin-stimulated cytoskeletal rearrangement.

Alenghat FJ, Baca QJ, Rubin NT, Pao LI, Matozaki T, Lowell CA, Golan DE, Neel BG, Swanson KD.

J Cell Sci. 2012 Nov 15;125(Pt 22):5535-45. doi: 10.1242/jcs.111260. Epub 2012 Sep 12.


Activation of the alternative complement pathway in vitreous is controlled by genetics in age-related macular degeneration.

Loyet KM, Deforge LE, Katschke KJ Jr, Diehl L, Graham RR, Pao L, Sturgeon L, Lewin-Koh SC, Hollyfield JG, van Lookeren Campagne M.

Invest Ophthalmol Vis Sci. 2012 Sep 25;53(10):6628-37.


Hepatocyte-specific Ptpn6 deletion protects from obesity-linked hepatic insulin resistance.

Xu E, Charbonneau A, Rolland Y, Bellmann K, Pao L, Siminovitch KA, Neel BG, Beauchemin N, Marette A.

Diabetes. 2012 Aug;61(8):1949-58. doi: 10.2337/db11-1502. Epub 2012 Jun 14.


Validated LC-MS-MS method for the determination of quetiapine in human plasma: application to a pharmacokinetic study.

Pan RN, Kuo BP, Pao LH.

J Chromatogr Sci. 2012 Mar;50(3):277-82. doi: 10.1093/chromsci/bms001.


Herb-drug interaction of 50 Chinese herbal medicines on CYP3A4 activity in vitro and in vivo.

Pao LH, Hu OY, Fan HY, Lin CC, Liu LC, Huang PW.

Am J Chin Med. 2012;40(1):57-73.


Lactation defect in a widely used MMTV-Cre transgenic line of mice.

Yuan T, Wang Y, Pao L, Anderson SM, Gu H.

PLoS One. 2011 Apr 29;6(4):e19233. doi: 10.1371/journal.pone.0019233.


Simultaneous quantification of triazolam and its metabolites in human urine by liquid chromatography-tandem mass spectrometry.

Pan RN, Hsiong CH, Huang PW, Tsai WS, Li WY, Pao LH.

J Anal Toxicol. 2011 Apr;35(3):170-5.


SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells.

Fowler CC, Pao LI, Blattman JN, Greenberg PD.

J Immunol. 2010 Sep 15;185(6):3256-67. doi: 10.4049/jimmunol.1001362. Epub 2010 Aug 9.


Determination of p-aminohippuric acid in rat plasma by liquid chromatography-tandem mass spectrometry.

Fan HY, Lin CC, Pao LH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Jun 1;878(19):1643-6. doi: 10.1016/j.jchromb.2010.04.015. Epub 2010 Apr 24. Erratum in: J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Aug 1;878(23):2173.


Stability analysis of the GAL regulatory network in Saccharomyces cerevisiae and Kluyveromyces lactis.

Kulkarni VV, Kareenhalli V, Malakar P, Pao LY, Safonov MG, Viswanathan GA.

BMC Bioinformatics. 2010 Jan 18;11 Suppl 1:S43. doi: 10.1186/1471-2105-11-S1-S43.


Quantitative rat liver function test by galactose single point method.

Young TH, Tang HS, Chao YC, Lee HS, Hsiong CH, Pao LH, Hu OY.

Lab Anim. 2008 Oct;42(4):495-504. doi: 10.1258/la.2007.06040e.


Simultaneous determination of triazolam and its metabolites in human plasma by liquid chromatography-tandem mass spectrometry.

Pan RN, Lin CC, Huang PW, Hsiong CH, Pao LH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Sep 1;872(1-2):58-62. doi: 10.1016/j.jchromb.2008.07.014. Epub 2008 Jul 23.


B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity.

Pao LI, Lam KP, Henderson JM, Kutok JL, Alimzhanov M, Nitschke L, Thomas ML, Neel BG, Rajewsky K.

Immunity. 2007 Jul;27(1):35-48. Epub 2007 Jun 28.


Nonreceptor protein-tyrosine phosphatases in immune cell signaling.

Pao LI, Badour K, Siminovitch KA, Neel BG.

Annu Rev Immunol. 2007;25:473-523. Review.


SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms.

Nagaishi T, Pao L, Lin SH, Iijima H, Kaser A, Qiao SW, Chen Z, Glickman J, Najjar SM, Nakajima A, Neel BG, Blumberg RS.

Immunity. 2006 Nov;25(5):769-81. Epub 2006 Nov 2.


Functional analysis of granzyme M and its role in immunity to infection.

Pao LI, Sumaria N, Kelly JM, van Dommelen S, Cretney E, Wallace ME, Anthony DA, Uldrich AP, Godfrey DI, Papadimitriou JM, Mullbacher A, Degli-Esposti MA, Smyth MJ.

J Immunol. 2005 Sep 1;175(5):3235-43.


Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase.

Luo J, Sobkiw CL, Logsdon NM, Watt JM, Signoretti S, O'Connell F, Shin E, Shim Y, Pao L, Neel BG, Depinho RA, Loda M, Cantley LC.

Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10238-43. Epub 2005 Jul 8.


In vitro and in vivo evaluation of the metabolism and pharmacokinetics of sebacoyl dinalbuphine.

Pao LH, Hsiong CH, Hu OY, Wang JJ, Ho ST.

Drug Metab Dispos. 2005 Mar;33(3):395-402. Epub 2004 Dec 17.


Synergistic visual/haptic rendering modes for scientific visualization.

Lawrence DA, Pao LY, Lee CD, Novoselov RY.

IEEE Comput Graph Appl. 2004 Nov-Dec;24(6):22-30. No abstract available.


Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.

Araki T, Mohi MG, Ismat FA, Bronson RT, Williams IR, Kutok JL, Yang W, Pao LI, Gilliland DG, Epstein JA, Neel BG.

Nat Med. 2004 Aug;10(8):849-57. Epub 2004 Jul 25.


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