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Items: 1 to 50 of 117

1.

Renal proximal tubular epithelial cells exert immunomodulatory function by driving inflammatory CD4+ T-cell responses.

Breda PC, Wiech T, Meyer-Schwesinger C, Grahammer F, Huber TB, Panzer U, Tiegs G, Neumann K.

Am J Physiol Renal Physiol. 2019 Apr 24. doi: 10.1152/ajprenal.00427.2018. [Epub ahead of print]

PMID:
31017008
2.

The co-inhibitory molecule PD-L1 contributes to regulatory T cell-mediated protection in murine crescentic glomerulonephritis.

Neumann K, Ostmann A, Breda PC, Ochel A, Tacke F, Paust HJ, Panzer U, Tiegs G.

Sci Rep. 2019 Feb 14;9(1):2038. doi: 10.1038/s41598-018-38432-3.

3.

Endogenous IL-22 is dispensable for experimental glomerulonephritis.

Gnirck AC, Wunderlich M, Becker M, Xiong T, Weinert E, Meyer-Schwesinger C, Dumoutier L, Renauld JC, Huber S, Panzer U, Turner JE.

Am J Physiol Renal Physiol. 2019 Apr 1;316(4):F712-F722. doi: 10.1152/ajprenal.00303.2018. Epub 2019 Feb 6.

PMID:
30724106
4.

Role of regulatory T cells in experimental autoimmune glomerulonephritis.

Klinge S, Yan K, Reimers D, Brede KM, Schmid J, Paust HJ, Krebs CF, Panzer U, Hopfer H, Mittrücker HW.

Am J Physiol Renal Physiol. 2019 Mar 1;316(3):F572-F581. doi: 10.1152/ajprenal.00558.2018. Epub 2019 Jan 16.

PMID:
30648909
5.

Mechanisms and functions of IL-17 signaling in renal autoimmune diseases.

Schmidt T, Luebbe J, Paust HJ, Panzer U.

Mol Immunol. 2018 Dec;104:90-99. doi: 10.1016/j.molimm.2018.09.005. Epub 2018 Nov 15. Review.

PMID:
30448610
6.

Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3+ Regulatory T Cells.

Mathies F, Steffens N, Kleinschmidt D, Stuhlmann F, Huber FJ, Roy U, Meyer T, Luetgehetmann M, von Petersdorff M, Seiz O, Herkel J, Schramm C, Flavell RA, Gagliani N, Krebs C, Panzer U, Abdullah Z, Strowig T, Bedke T, Huber S.

J Immunol. 2018 Dec 15;201(12):3558-3568. doi: 10.4049/jimmunol.1800711. Epub 2018 Nov 16.

PMID:
30446566
7.

Development and validation of a renal risk score in ANCA-associated glomerulonephritis.

Brix SR, Noriega M, Tennstedt P, Vettorazzi E, Busch M, Nitschke M, Jabs WJ, Özcan F, Wendt R, Hausberg M, Sellin L, Panzer U, Huber TB, Waldherr R, Hopfer H, Stahl RAK, Wiech T.

Kidney Int. 2018 Dec;94(6):1177-1188. doi: 10.1016/j.kint.2018.07.020. Epub 2018 Oct 29.

PMID:
30385041
8.

T cell-derived IFN-γ downregulates protective group 2 innate lymphoid cells in murine lupus erythematosus.

Düster M, Becker M, Gnirck AC, Wunderlich M, Panzer U, Turner JE.

Eur J Immunol. 2018 Aug;48(8):1364-1375. doi: 10.1002/eji.201747303. Epub 2018 May 17.

PMID:
29671873
9.

IL-17C/IL-17 Receptor E Signaling in CD4+ T Cells Promotes TH17 Cell-Driven Glomerular Inflammation.

Krohn S, Nies JF, Kapffer S, Schmidt T, Riedel JH, Kaffke A, Peters A, Borchers A, Steinmetz OM, Krebs CF, Turner JE, Brix SR, Paust HJ, Stahl RAK, Panzer U.

J Am Soc Nephrol. 2018 Apr;29(4):1210-1222. doi: 10.1681/ASN.2017090949. Epub 2018 Feb 26.

10.

Organisation of lymphocytic infiltrates in ANCA-associated glomerulonephritis.

Brix SR, Noriega M, Herden EM, Goldmann B, Langbehn U, Busch M, Jabs WJ, Steinmetz OM, Panzer U, Huber TB, Stahl RAK, Wiech T.

Histopathology. 2018 Jun;72(7):1093-1101. doi: 10.1111/his.13487. Epub 2018 Mar 25.

PMID:
29453894
11.

Plasticity and heterogeneity of Th17 in immune-mediated kidney diseases.

Krebs CF, Panzer U.

J Autoimmun. 2018 Feb;87:61-68. doi: 10.1016/j.jaut.2017.12.005. Epub 2017 Dec 21. Review.

PMID:
29275837
12.

Host DNases prevent vascular occlusion by neutrophil extracellular traps.

Jiménez-Alcázar M, Rangaswamy C, Panda R, Bitterling J, Simsek YJ, Long AT, Bilyy R, Krenn V, Renné C, Renné T, Kluge S, Panzer U, Mizuta R, Mannherz HG, Kitamura D, Herrmann M, Napirei M, Fuchs TA.

Science. 2017 Dec 1;358(6367):1202-1206. doi: 10.1126/science.aam8897.

PMID:
29191910
13.

Tissue-Resident Lymphocytes in the Kidney.

Turner JE, Becker M, Mittrücker HW, Panzer U.

J Am Soc Nephrol. 2018 Feb;29(2):389-399. doi: 10.1681/ASN.2017060599. Epub 2017 Nov 1.

14.

Effects of Two Immunosuppressive Treatment Protocols for IgA Nephropathy.

Rauen T, Fitzner C, Eitner F, Sommerer C, Zeier M, Otte B, Panzer U, Peters H, Benck U, Mertens PR, Kuhlmann U, Witzke O, Gross O, Vielhauer V, Mann JFE, Hilgers RD, Floege J.

J Am Soc Nephrol. 2018 Jan;29(1):317-325. doi: 10.1681/ASN.2017060713. Epub 2017 Oct 17.

15.

T helper type 17 cells in immune-mediated glomerular disease.

Krebs CF, Schmidt T, Riedel JH, Panzer U.

Nat Rev Nephrol. 2017 Oct;13(10):647-659. doi: 10.1038/nrneph.2017.112. Epub 2017 Aug 7. Review.

PMID:
28781371
16.

A novel in vivo method to quantify slit diaphragm protein abundance in murine proteinuric kidney disease.

Haase R, Potthoff SA, Meyer-Schwesinger C, Frosch C, Wiech T, Panzer U, Königshausen E, Stegbauer J, Sellin L, Rump LC, Quack I, Woznowski M.

PLoS One. 2017 Jun 12;12(6):e0179217. doi: 10.1371/journal.pone.0179217. eCollection 2017.

17.

IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis.

Riedel JH, Becker M, Kopp K, Düster M, Brix SR, Meyer-Schwesinger C, Kluth LA, Gnirck AC, Attar M, Krohn S, Fehse B, Stahl RAK, Panzer U, Turner JE.

J Am Soc Nephrol. 2017 Jul;28(7):2068-2080. doi: 10.1681/ASN.2016080877. Epub 2017 Feb 2.

18.

Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles.

Ergen C, Heymann F, Al Rawashdeh W, Gremse F, Bartneck M, Panzer U, Pola R, Pechar M, Storm G, Mohr N, Barz M, Zentel R, Kiessling F, Trautwein C, Lammers T, Tacke F.

Biomaterials. 2017 Jan;114:106-120. doi: 10.1016/j.biomaterials.2016.11.009. Epub 2016 Nov 9.

PMID:
27855336
19.

Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney.

Krebs CF, Paust HJ, Krohn S, Koyro T, Brix SR, Riedel JH, Bartsch P, Wiech T, Meyer-Schwesinger C, Huang J, Fischer N, Busch P, Mittrücker HW, Steinhoff U, Stockinger B, Perez LG, Wenzel UO, Janneck M, Steinmetz OM, Gagliani N, Stahl RAK, Huber S, Turner JE, Panzer U.

Immunity. 2016 Nov 15;45(5):1078-1092. doi: 10.1016/j.immuni.2016.10.020.

20.

CD103+ Kidney Dendritic Cells Protect against Crescentic GN by Maintaining IL-10-Producing Regulatory T Cells.

Evers BD, Engel DR, Böhner AM, Tittel AP, Krause TA, Heuser C, Garbi N, Kastenmüller W, Mack M, Tiegs G, Panzer U, Boor P, Ludwig-Portugall I, Kurts C.

J Am Soc Nephrol. 2016 Nov;27(11):3368-3382. Epub 2016 Apr 1.

21.

An Indirect Immunofluorescence Method Facilitates Detection of Thrombospondin Type 1 Domain-Containing 7A-Specific Antibodies in Membranous Nephropathy.

Hoxha E, Beck LH Jr, Wiech T, Tomas NM, Probst C, Mindorf S, Meyer-Schwesinger C, Zahner G, Stahl PR, Schöpper R, Panzer U, Harendza S, Helmchen U, Salant DJ, Stahl RA.

J Am Soc Nephrol. 2017 Feb;28(2):520-531. doi: 10.1681/ASN.2016010050. Epub 2016 Jul 19.

22.

T-Bet Enhances Regulatory T Cell Fitness and Directs Control of Th1 Responses in Crescentic GN.

Nosko A, Kluger MA, Diefenhardt P, Melderis S, Wegscheid C, Tiegs G, Stahl RA, Panzer U, Steinmetz OM.

J Am Soc Nephrol. 2017 Jan;28(1):185-196. doi: 10.1681/ASN.2015070820. Epub 2016 Jun 13.

23.

Plasticity of Th17 Cells in Autoimmune Kidney Diseases.

Krebs CF, Turner JE, Paust HJ, Kapffer S, Koyro T, Krohn S, Ufer F, Friese MA, Flavell RA, Stockinger B, Steinmetz OM, Stahl RA, Huber S, Panzer U.

J Immunol. 2016 Jul 15;197(2):449-57. doi: 10.4049/jimmunol.1501831. Epub 2016 Jun 6.

24.

A Mechanism for Cancer-Associated Membranous Nephropathy.

Hoxha E, Wiech T, Stahl PR, Zahner G, Tomas NM, Meyer-Schwesinger C, Wenzel U, Janneck M, Steinmetz OM, Panzer U, Harendza S, Stahl RA.

N Engl J Med. 2016 May 19;374(20):1995-6. doi: 10.1056/NEJMc1511702. No abstract available.

PMID:
27192690
25.

IL-17F Promotes Tissue Injury in Autoimmune Kidney Diseases.

Riedel JH, Paust HJ, Krohn S, Turner JE, Kluger MA, Steinmetz OM, Krebs CF, Stahl RA, Panzer U.

J Am Soc Nephrol. 2016 Dec;27(12):3666-3677. Epub 2016 Mar 30.

26.

Intensive Supportive Care plus Immunosuppression in IgA Nephropathy.

Rauen T, Eitner F, Fitzner C, Sommerer C, Zeier M, Otte B, Panzer U, Peters H, Benck U, Mertens PR, Kuhlmann U, Witzke O, Gross O, Vielhauer V, Mann JF, Hilgers RD, Floege J; STOP-IgAN Investigators.

N Engl J Med. 2015 Dec 3;373(23):2225-36. doi: 10.1056/NEJMoa1415463.

27.

Inhibitor of NFκB Kinase Subunit 2 Blockade Hinders the Initiation but Aggravates the Progression of Crescentic GN.

Gotot J, Piotrowski E, Otte MS, Tittel AP, Linlin G, Yao C, Ziegelbauer K, Panzer U, Garbi N, Kurts C, Thaiss F.

J Am Soc Nephrol. 2016 Jul;27(7):1917-24. doi: 10.1681/ASN.2015060699. Epub 2015 Nov 16.

28.

CXCR3+ Regulatory T Cells Control TH1 Responses in Crescentic GN.

Paust HJ, Riedel JH, Krebs CF, Turner JE, Brix SR, Krohn S, Velden J, Wiech T, Kaffke A, Peters A, Bennstein SB, Kapffer S, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Thaiss F, Mittrücker HW, Steinmetz OM, Stahl RA, Panzer U.

J Am Soc Nephrol. 2016 Jul;27(7):1933-42. doi: 10.1681/ASN.2015020203. Epub 2015 Nov 3.

29.

Treg17 cells are programmed by Stat3 to suppress Th17 responses in systemic lupus.

Kluger MA, Melderis S, Nosko A, Goerke B, Luig M, Meyer MC, Turner JE, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Stahl RA, Panzer U, Steinmetz OM.

Kidney Int. 2016 Jan;89(1):158-66. doi: 10.1038/ki.2015.296. Epub 2016 Jan 4.

PMID:
26466322
30.

Spontaneous remission of proteinuria is a frequent event in phospholipase A2 receptor antibody-negative patients with membranous nephropathy.

Hoxha E, Harendza S, Pinnschmidt HO, Tomas NM, Helmchen U, Panzer U, Stahl RA.

Nephrol Dial Transplant. 2015 Nov;30(11):1862-9. doi: 10.1093/ndt/gfv228. Epub 2015 Jul 3.

PMID:
26142398
31.

RORγt(+)Foxp3(+) Cells are an Independent Bifunctional Regulatory T Cell Lineage and Mediate Crescentic GN.

Kluger MA, Meyer MC, Nosko A, Goerke B, Luig M, Wegscheid C, Tiegs G, Stahl RA, Panzer U, Steinmetz OM.

J Am Soc Nephrol. 2016 Feb;27(2):454-65. doi: 10.1681/ASN.2014090880. Epub 2015 Jun 8.

32.

TH1 and TH17 cells promote crescent formation in experimental autoimmune glomerulonephritis.

Hünemörder S, Treder J, Ahrens S, Schumacher V, Paust HJ, Menter T, Matthys P, Kamradt T, Meyer-Schwesinger C, Panzer U, Hopfer H, Mittrücker HW.

J Pathol. 2015 Sep;237(1):62-71. doi: 10.1002/path.4559. Epub 2015 Jun 11.

PMID:
25965582
33.

Glomerulopathy induced by immunization with a peptide derived from the goodpasture antigen α3IV-NC1.

Hopfer H, Hünemörder S, Treder J, Turner JE, Paust HJ, Meyer-Schwesinger C, Hopfer U, Sachs M, Peters A, Bucher-Kocaoglu B, Ahrens S, Panzer U, Mittrücker HW.

J Immunol. 2015 Apr 15;194(8):3646-55. doi: 10.4049/jimmunol.1401267. Epub 2015 Mar 13.

34.

CC Chemokine Ligand 18 in ANCA-Associated Crescentic GN.

Brix SR, Stege G, Disteldorf E, Hoxha E, Krebs C, Krohn S, Otto B, Klätschke K, Herden E, Heymann F, Lira SA, Tacke F, Wolf G, Busch M, Jabs WJ, Özcan F, Keller F, Beige J, Wagner K, Helmchen U, Noriega M, Wiech T, Panzer U, Stahl RA.

J Am Soc Nephrol. 2015 Sep;26(9):2105-17. doi: 10.1681/ASN.2014040407. Epub 2015 Mar 11.

35.

Inflammation-Induced IL-6 Functions as a Natural Brake on Macrophages and Limits GN.

Luig M, Kluger MA, Goerke B, Meyer M, Nosko A, Yan I, Scheller J, Mittrücker HW, Rose-John S, Stahl RA, Panzer U, Steinmetz OM.

J Am Soc Nephrol. 2015 Jul;26(7):1597-607. doi: 10.1681/ASN.2014060620. Epub 2015 Feb 5.

36.

Function of the Th17/interleukin-17A immune response in murine lupus nephritis.

Schmidt T, Paust HJ, Krebs CF, Turner JE, Kaffke A, Bennstein SB, Koyro T, Peters A, Velden J, Hünemörder S, Haag F, Steinmetz OM, Mittrücker HW, Stahl RA, Panzer U.

Arthritis Rheumatol. 2015 Feb;67(2):475-87. doi: 10.1002/art.38955.

37.

PLA2R antibody levels and clinical outcome in patients with membranous nephropathy and non-nephrotic range proteinuria under treatment with inhibitors of the renin-angiotensin system.

Hoxha E, Harendza S, Pinnschmidt H, Panzer U, Stahl RA.

PLoS One. 2014 Oct 14;9(10):e110681. doi: 10.1371/journal.pone.0110681. eCollection 2014.

38.

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.

Kiryluk K, Li Y, Scolari F, Sanna-Cherchi S, Choi M, Verbitsky M, Fasel D, Lata S, Prakash S, Shapiro S, Fischman C, Snyder HJ, Appel G, Izzi C, Viola BF, Dallera N, Del Vecchio L, Barlassina C, Salvi E, Bertinetto FE, Amoroso A, Savoldi S, Rocchietti M, Amore A, Peruzzi L, Coppo R, Salvadori M, Ravani P, Magistroni R, Ghiggeri GM, Caridi G, Bodria M, Lugani F, Allegri L, Delsante M, Maiorana M, Magnano A, Frasca G, Boer E, Boscutti G, Ponticelli C, Mignani R, Marcantoni C, Di Landro D, Santoro D, Pani A, Polci R, Feriozzi S, Chicca S, Galliani M, Gigante M, Gesualdo L, Zamboli P, Battaglia GG, Garozzo M, Maixnerová D, Tesar V, Eitner F, Rauen T, Floege J, Kovacs T, Nagy J, Mucha K, Pączek L, Zaniew M, Mizerska-Wasiak M, Roszkowska-Blaim M, Pawlaczyk K, Gale D, Barratt J, Thibaudin L, Berthoux F, Canaud G, Boland A, Metzger M, Panzer U, Suzuki H, Goto S, Narita I, Caliskan Y, Xie J, Hou P, Chen N, Zhang H, Wyatt RJ, Novak J, Julian BA, Feehally J, Stengel B, Cusi D, Lifton RP, Gharavi AG.

Nat Genet. 2014 Nov;46(11):1187-96. doi: 10.1038/ng.3118. Epub 2014 Oct 12.

39.

MicroRNA-193a Regulates the Transdifferentiation of Human Parietal Epithelial Cells toward a Podocyte Phenotype.

Kietzmann L, Guhr SS, Meyer TN, Ni L, Sachs M, Panzer U, Stahl RA, Saleem MA, Kerjaschki D, Gebeshuber CA, Meyer-Schwesinger C.

J Am Soc Nephrol. 2015 Jun;26(6):1389-401. doi: 10.1681/ASN.2014020190. Epub 2014 Sep 30.

40.

M-type phospholipase A2 receptor autoantibodies and renal function in patients with primary membranous nephropathy.

Hoxha E, Harendza S, Pinnschmidt H, Panzer U, Stahl RA.

Clin J Am Soc Nephrol. 2014 Nov 7;9(11):1883-90. doi: 10.2215/CJN.03850414. Epub 2014 Sep 29.

41.

Neuropsychological outcome after complicated Shiga toxin-producing Escherichia coli infection.

Simova O, Weineck G, Schuetze T, Wegscheider K, Panzer U, Stahl RA, Gerloff C, Magnus T.

PLoS One. 2014 Jul 22;9(7):e103029. doi: 10.1371/journal.pone.0103029. eCollection 2014.

42.

CXCL5 drives neutrophil recruitment in TH17-mediated GN.

Disteldorf EM, Krebs CF, Paust HJ, Turner JE, Nouailles G, Tittel A, Meyer-Schwesinger C, Stege G, Brix S, Velden J, Wiech T, Helmchen U, Steinmetz OM, Peters A, Bennstein SB, Kaffke A, Llanto C, Lira SA, Mittrücker HW, Stahl RA, Kurts C, Kaufmann SH, Panzer U.

J Am Soc Nephrol. 2015 Jan;26(1):55-66. doi: 10.1681/ASN.2013101061. Epub 2014 Jun 5.

43.

The function of the chemokine receptor CXCR6 in the T cell response of mice against Listeria monocytogenes.

Heesch K, Raczkowski F, Schumacher V, Hünemörder S, Panzer U, Mittrücker HW.

PLoS One. 2014 May 15;9(5):e97701. doi: 10.1371/journal.pone.0097701. eCollection 2014.

44.

Phospholipase A2 receptor autoantibodies and clinical outcome in patients with primary membranous nephropathy.

Hoxha E, Thiele I, Zahner G, Panzer U, Harendza S, Stahl RA.

J Am Soc Nephrol. 2014 Jun;25(6):1357-66. doi: 10.1681/ASN.2013040430. Epub 2014 Mar 7.

45.

Stat3 programs Th17-specific regulatory T cells to control GN.

Kluger MA, Luig M, Wegscheid C, Goerke B, Paust HJ, Brix SR, Yan I, Mittrücker HW, Hagl B, Renner ED, Tiegs G, Wiech T, Stahl RA, Panzer U, Steinmetz OM.

J Am Soc Nephrol. 2014 Jun;25(6):1291-302. doi: 10.1681/ASN.2013080904. Epub 2014 Feb 7.

46.

Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium.

Schiwon M, Weisheit C, Franken L, Gutweiler S, Dixit A, Meyer-Schwesinger C, Pohl JM, Maurice NJ, Thiebes S, Lorenz K, Quast T, Fuhrmann M, Baumgarten G, Lohse MJ, Opdenakker G, Bernhagen J, Bucala R, Panzer U, Kolanus W, Gröne HJ, Garbi N, Kastenmüller W, Knolle PA, Kurts C, Engel DR.

Cell. 2014 Jan 30;156(3):456-68. doi: 10.1016/j.cell.2014.01.006.

47.

Deficiency of the interleukin 17/23 axis accelerates renal injury in mice with deoxycorticosterone acetate+angiotensin ii-induced hypertension.

Krebs CF, Lange S, Niemann G, Rosendahl A, Lehners A, Meyer-Schwesinger C, Stahl RA, Benndorf RA, Velden J, Paust HJ, Panzer U, Ehmke H, Wenzel UO.

Hypertension. 2014 Mar;63(3):565-71. doi: 10.1161/HYPERTENSIONAHA.113.02620. Epub 2013 Dec 23.

PMID:
24366079
48.

IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation.

Turner JE, Morrison PJ, Wilhelm C, Wilson M, Ahlfors H, Renauld JC, Panzer U, Helmby H, Stockinger B.

J Exp Med. 2013 Dec 16;210(13):2951-65. doi: 10.1084/jem.20130071. Epub 2013 Nov 18.

49.

B-cell-derived IL-10 does not vitally contribute to the clinical course of glomerulonephritis.

Kluger MA, Ostmann A, Luig M, Meyer MC, Goerke B, Paust HJ, Meyer-Schwesinger C, Stahl RA, Panzer U, Tiegs G, Steinmetz OM.

Eur J Immunol. 2014 Mar;44(3):683-93. doi: 10.1002/eji.201343842. Epub 2013 Dec 16.

50.

The immune system and kidney disease: basic concepts and clinical implications.

Kurts C, Panzer U, Anders HJ, Rees AJ.

Nat Rev Immunol. 2013 Oct;13(10):738-53. doi: 10.1038/nri3523. Epub 2013 Sep 16. Review.

PMID:
24037418

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