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Items: 1 to 50 of 72

1.

Combination of sunitinib and PD-L1 blockade enhances anticancer efficacy of TLR7/8 agonist-based nanovaccine.

Kim H, Khanna V, Kucaba TA, Zhang W, Ferguson DM, Griffith TS, Panyam J.

Mol Pharm. 2019 Jan 8. doi: 10.1021/acs.molpharmaceut.8b01165. [Epub ahead of print]

PMID:
30620878
2.

poly(D,L-lactide-co-glycolide) nanoparticles as a vaccine delivery platform for TLR7/8 agonist-based cancer vaccine.

Kim H, Griffith T, Panyam J.

J Pharmacol Exp Ther. 2019 Jan 4. pii: jpet.118.254953. doi: 10.1124/jpet.118.254953. [Epub ahead of print]

3.

Intradermal delivery of vaccine nanoparticles using hollow microneedle array generates enhanced and balanced immune response.

Niu L, Chu LY, Burton SA, Hansen KJ, Panyam J.

J Control Release. 2018 Dec 17;294:268-278. doi: 10.1016/j.jconrel.2018.12.026. [Epub ahead of print]

PMID:
30572036
4.

Acidic pH-responsive polymer nanoparticles as a TLR7/8 agonist delivery platform for cancer immunotherapy.

Kim H, Sehgal D, Kucaba TA, Ferguson DM, Griffith TS, Panyam J.

Nanoscale. 2018 Nov 15;10(44):20851-20862. doi: 10.1039/c8nr07201a.

PMID:
30403212
5.

Inhibition of Chlamydia trachomatis Growth During the Last Decade: A Mini-Review.

Serradji N, Vu TH, Kim H, Panyam J, Verbeke P.

Mini Rev Med Chem. 2018;18(16):1363-1372. doi: 10.2174/1389557518666180423152613. Review.

PMID:
29692244
6.

Nano-Engineered Mesenchymal Stem Cells Increase Therapeutic Efficacy of Anticancer Drug Through True Active Tumor Targeting.

Layek B, Sadhukha T, Panyam J, Prabha S.

Mol Cancer Ther. 2018 Jun;17(6):1196-1206. doi: 10.1158/1535-7163.MCT-17-0682. Epub 2018 Mar 28.

7.

Polymeric nanoparticles encapsulating novel TLR7/8 agonists as immunostimulatory adjuvants for enhanced cancer immunotherapy.

Kim H, Niu L, Larson P, Kucaba TA, Murphy KA, James BR, Ferguson DM, Griffith TS, Panyam J.

Biomaterials. 2018 May;164:38-53. doi: 10.1016/j.biomaterials.2018.02.034. Epub 2018 Feb 17.

PMID:
29482062
8.

The effects of collagen-rich extracellular matrix on the intracellular delivery of glycol chitosan nanoparticles in human lung fibroblasts.

Yhee JY, Yoon HY, Kim H, Jeon S, Hergert P, Im J, Panyam J, Kim K, Nho RS.

Int J Nanomedicine. 2017 Aug 21;12:6089-6105. doi: 10.2147/IJN.S138129. eCollection 2017.

9.

Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling.

Song JM, Molla K, Anandharaj A, Cornax I, O Sullivan MG, Kirtane AR, Panyam J, Kassie F.

Oncotarget. 2017 Apr 18;8(16):26927-26940. doi: 10.18632/oncotarget.15879.

10.

Chemopreventive efficacy of curcumin-loaded PLGA microparticles in a transgenic mouse model of HER-2-positive breast cancer.

Grill AE, Shahani K, Koniar B, Panyam J.

Drug Deliv Transl Res. 2018 Apr;8(2):329-341. doi: 10.1007/s13346-017-0377-4.

PMID:
28417445
11.

Evaluation of Vaginal Drug Levels and Safety of a Locally Administered Glycerol Monolaurate Cream in Rhesus Macaques.

Kirtane AR, Rothenberger MK, Frieberg A, Nephew K, Schultz-Darken N, Schmidt T, Reimann T, Haase AT, Panyam J.

J Pharm Sci. 2017 Jul;106(7):1821-1827. doi: 10.1016/j.xphs.2017.03.030. Epub 2017 Apr 4.

12.

Engineering of Anti-CD133 Trispecific Molecule Capable of Inducing NK Expansion and Driving Antibody-Dependent Cell-Mediated Cytotoxicity.

Schmohl JU, Felices M, Oh F, Lenvik AJ, Lebeau AM, Panyam J, Miller JS, Vallera DA.

Cancer Res Treat. 2017 Oct;49(4):1140-1152. doi: 10.4143/crt.2016.491. Epub 2017 Feb 20.

13.

Fibrinolytic Enzyme Cotherapy Improves Tumor Perfusion and Therapeutic Efficacy of Anticancer Nanomedicine.

Kirtane AR, Sadhukha T, Kim H, Khanna V, Koniar B, Panyam J.

Cancer Res. 2017 Mar 15;77(6):1465-1475. doi: 10.1158/0008-5472.CAN-16-1646. Epub 2017 Jan 20.

14.

Freeze concentration-induced PLGA and polystyrene nanoparticle aggregation: Imaging and rational design of lyoprotection.

Niu L, Panyam J.

J Control Release. 2017 Feb 28;248:125-132. doi: 10.1016/j.jconrel.2017.01.019. Epub 2017 Jan 14.

PMID:
28093299
15.

Assessing the Benefits of Drug Delivery by Nanocarriers: A Partico/Pharmacokinetic Framework.

Siegel RA, Kirtane AR, Panyam J.

IEEE Trans Biomed Eng. 2017 Sep;64(9):2176-2185. doi: 10.1109/TBME.2016.2632733. Epub 2016 Nov 29.

PMID:
27913319
16.

Honokiol suppresses lung tumorigenesis by targeting EGFR and its downstream effectors.

Song JM, Anandharaj A, Upadhyaya P, Kirtane AR, Kim JH, Hong KH, Panyam J, Kassie F.

Oncotarget. 2016 Sep 6;7(36):57752-57769. doi: 10.18632/oncotarget.10759.

17.

Nanoparticles Containing High Loads of Paclitaxel-Silicate Prodrugs: Formulation, Drug Release, and Anticancer Efficacy.

Han J, Michel AR, Lee HS, Kalscheuer S, Wohl A, Hoye TR, McCormick AV, Panyam J, Macosko CW.

Mol Pharm. 2015 Dec 7;12(12):4329-35. doi: 10.1021/acs.molpharmaceut.5b00530. Epub 2015 Nov 4.

18.

Reformulating Tylocrebrine in Epidermal Growth Factor Receptor Targeted Polymeric Nanoparticles Improves Its Therapeutic Index.

Kirtane AR, Wong HL, Guru BR, Lis LG, Georg GI, Gurvich VJ, Panyam J.

Mol Pharm. 2015 Aug 3;12(8):2912-23. doi: 10.1021/acs.molpharmaceut.5b00173. Epub 2015 Jul 3.

19.

Attenuated Salmonella enterica Typhimurium reduces tumor burden in an autochthonous breast cancer model.

Drees J, Mertensotto M, Liu G, Panyam J, Leonard A, Augustin L, Schottel J, Saltzman D.

Anticancer Res. 2015 Feb;35(2):843-9.

PMID:
25667465
20.

A pharmacokinetic model for quantifying the effect of vascular permeability on the choice of drug carrier: a framework for personalized nanomedicine.

Kirtane AR, Siegel RA, Panyam J.

J Pharm Sci. 2015 Mar;104(3):1174-86. doi: 10.1002/jps.24302. Epub 2015 Jan 12.

PMID:
25583443
21.

Co-delivery of natural metabolic inhibitors in a self-microemulsifying drug delivery system for improved oral bioavailability of curcumin.

Grill AE, Koniar B, Panyam J.

Drug Deliv Transl Res. 2014 Aug;4(4):344-52. doi: 10.1007/s13346-014-0199-6.

22.

Intranasal delivery of liposomal indole-3-carbinol improves its pulmonary bioavailability.

Song JM, Kirtane AR, Upadhyaya P, Qian X, Balbo S, Teferi F, Panyam J, Kassie F.

Int J Pharm. 2014 Dec 30;477(1-2):96-101. doi: 10.1016/j.ijpharm.2014.10.018. Epub 2014 Oct 11.

23.

Enhanced photodynamic therapy and effective elimination of cancer stem cells using surfactant-polymer nanoparticles.

Usacheva M, Swaminathan SK, Kirtane AR, Panyam J.

Mol Pharm. 2014 Sep 2;11(9):3186-95. doi: 10.1021/mp5003619. Epub 2014 Aug 6.

PMID:
25061685
24.

Synthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide)-based nanoformulation of miRNA-150: potential implications for pancreatic cancer therapy.

Arora S, Swaminathan SK, Kirtane A, Srivastava SK, Bhardwaj A, Singh S, Panyam J, Singh AP.

Int J Nanomedicine. 2014 Jun 18;9:2933-42. doi: 10.2147/IJN.S61949. eCollection 2014.

25.

Enhancing therapeutic efficacy through designed aggregation of nanoparticles.

Sadhukha T, Wiedmann TS, Panyam J.

Biomaterials. 2014 Sep;35(27):7860-9. doi: 10.1016/j.biomaterials.2014.05.085. Epub 2014 Jun 16.

26.

Silicate esters of paclitaxel and docetaxel: synthesis, hydrophobicity, hydrolytic stability, cytotoxicity, and prodrug potential.

Wohl AR, Michel AR, Kalscheuer S, Macosko CW, Panyam J, Hoye TR.

J Med Chem. 2014 Mar 27;57(6):2368-79. doi: 10.1021/jm401708f. Epub 2014 Mar 6.

27.

Polymer nanoparticles: Weighing up gene delivery.

Kirtane AR, Panyam J.

Nat Nanotechnol. 2013 Nov;8(11):805-6. doi: 10.1038/nnano.2013.234. No abstract available.

PMID:
24202534
28.

Flash nanoprecipitation: particle structure and stability.

Pustulka KM, Wohl AR, Lee HS, Michel AR, Han J, Hoye TR, McCormick AV, Panyam J, Macosko CW.

Mol Pharm. 2013 Nov 4;10(11):4367-77. doi: 10.1021/mp400337f. Epub 2013 Oct 15.

29.

Exploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunities.

Kirtane AR, Kalscheuer SM, Panyam J.

Adv Drug Deliv Rev. 2013 Nov;65(13-14):1731-47. doi: 10.1016/j.addr.2013.09.001. Epub 2013 Sep 10. Review.

30.

CD133-targeted paclitaxel delivery inhibits local tumor recurrence in a mouse model of breast cancer.

Swaminathan SK, Roger E, Toti U, Niu L, Ohlfest JR, Panyam J.

J Control Release. 2013 Nov 10;171(3):280-7. doi: 10.1016/j.jconrel.2013.07.014. Epub 2013 Jul 18.

PMID:
23871962
31.

Inhalable magnetic nanoparticles for targeted hyperthermia in lung cancer therapy.

Sadhukha T, Wiedmann TS, Panyam J.

Biomaterials. 2013 Jul;34(21):5163-71. doi: 10.1016/j.biomaterials.2013.03.061. Epub 2013 Apr 13.

32.

Immunotoxin targeting CD133(+) breast carcinoma cells.

Ohlfest JR, Zellmer DM, Panyam J, Swaminathan SK, Oh S, Waldron NN, Toma S, Vallera DA.

Drug Deliv Transl Res. 2013 Apr;3(2):195-204. doi: 10.1007/s13346-012-0066-2.

PMID:
25787984
33.

Identification and characterization of a novel scFv recognizing human and mouse CD133.

Swaminathan SK, Niu L, Waldron N, Kalscheuer S, Zellmer DM, Olin MR, Ohlfest JR, Vallera DA, Panyam J.

Drug Deliv Transl Res. 2013 Apr;3(2):143-51. doi: 10.1007/s13346-012-0099-6.

34.

Cancer stem cells.

Panyam J.

Drug Deliv Transl Res. 2013 Apr;3(2):111-2. doi: 10.1007/s13346-013-0138-y. No abstract available.

PMID:
25787980
35.

Effective elimination of cancer stem cells by magnetic hyperthermia.

Sadhukha T, Niu L, Wiedmann TS, Panyam J.

Mol Pharm. 2013 Apr 1;10(4):1432-41. doi: 10.1021/mp400015b. Epub 2013 Mar 12.

PMID:
23432410
36.

Honokiol: a novel natural agent for cancer prevention and therapy.

Arora S, Singh S, Piazza GA, Contreras CM, Panyam J, Singh AP.

Curr Mol Med. 2012 Dec;12(10):1244-52. Review.

37.

Preparation of siRNA-encapsulated PLGA nanoparticles for sustained release of siRNA and evaluation of encapsulation efficiency.

Pantazis P, Dimas K, Wyche JH, Anant S, Houchen CW, Panyam J, Ramanujam RP.

Methods Mol Biol. 2012;906:311-9. doi: 10.1007/978-1-61779-953-2_25.

PMID:
22791444
38.

Folic acid functionalized nanoparticles for enhanced oral drug delivery.

Roger E, Kalscheuer S, Kirtane A, Guru BR, Grill AE, Whittum-Hudson J, Panyam J.

Mol Pharm. 2012 Jul 2;9(7):2103-10. doi: 10.1021/mp2005388. Epub 2012 Jun 13.

39.

Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1.

Schaefers MM, Breshears LM, Anderson MJ, Lin YC, Grill AE, Panyam J, Southern PJ, Schlievert PM, Peterson ML.

PLoS One. 2012;7(3):e32813. doi: 10.1371/journal.pone.0032813. Epub 2012 Mar 14.

40.

Image-guided drug delivery in lung cancer.

Wiedmann TS, Sadhukha T, Hammer BE, Panyam J.

Drug Deliv Transl Res. 2012 Feb;2(1):31-44. doi: 10.1007/s13346-011-0053-z.

PMID:
25786598
41.

Targeted delivery of antibiotics to intracellular chlamydial infections using PLGA nanoparticles.

Toti US, Guru BR, Hali M, McPharlin CM, Wykes SM, Panyam J, Whittum-Hudson JA.

Biomaterials. 2011 Sep;32(27):6606-13. doi: 10.1016/j.biomaterials.2011.05.038. Epub 2011 Jun 8.

42.

Highly loaded, sustained-release microparticles of curcumin for chemoprevention.

Shahani K, Panyam J.

J Pharm Sci. 2011 Jul;100(7):2599-609. doi: 10.1002/jps.22475. Epub 2011 Jan 14.

43.

Nanoparticle-mediated p53 gene therapy for tumor inhibition.

Sharma B, Ma W, Adjei IM, Panyam J, Dimitrijevic S, Labhasetwar V.

Drug Deliv Transl Res. 2011 Feb;1(1):43-52. doi: 10.1007/s13346-010-0008-9.

44.

Identification of a novel monoclonal antibody recognizing CD133.

Swaminathan SK, Olin MR, Forster CL, Cruz KS, Panyam J, Ohlfest JR.

J Immunol Methods. 2010 Sep 30;361(1-2):110-5. doi: 10.1016/j.jim.2010.07.007. Epub 2010 Jul 30.

PMID:
20674577
46.

Injectable sustained release microparticles of curcumin: a new concept for cancer chemoprevention.

Shahani K, Swaminathan SK, Freeman D, Blum A, Ma L, Panyam J.

Cancer Res. 2010 Jun 1;70(11):4443-52. doi: 10.1158/0008-5472.CAN-09-4362. Epub 2010 May 11.

47.

The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance.

Patil YB, Swaminathan SK, Sadhukha T, Ma L, Panyam J.

Biomaterials. 2010 Jan;31(2):358-65. doi: 10.1016/j.biomaterials.2009.09.048. Epub 2009 Oct 1.

48.

Nanoparticle-mediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance.

Khdair A, Chen D, Patil Y, Ma L, Dou QP, Shekhar MP, Panyam J.

J Control Release. 2010 Jan 25;141(2):137-44. doi: 10.1016/j.jconrel.2009.09.004. Epub 2009 Sep 11.

49.

A review of select recent patents on novel nanocarriers.

Grill AE, Johnston NW, Sadhukha T, Panyam J.

Recent Pat Drug Deliv Formul. 2009 Jun;3(2):137-42. Review.

PMID:
19519573
50.

Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance.

Patil Y, Sadhukha T, Ma L, Panyam J.

J Control Release. 2009 May 21;136(1):21-9. doi: 10.1016/j.jconrel.2009.01.021. Epub 2009 Feb 5.

PMID:
19331851

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