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Items: 8

1.

Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing.

Pankowicz FP, Barzi M, Kim KH, Legras X, Martins CS, Wooton-Kee CR, Lagor WR, Marini JC, Elsea SH, Bissig-Choisat B, Moore DD, Bissig KD.

Gastroenterology. 2018 Dec;155(6):1967-1970.e6. doi: 10.1053/j.gastro.2018.08.037. Epub 2018 Aug 28.

PMID:
30170115
2.

P450-Humanized and Human Liver Chimeric Mouse Models for Studying Xenobiotic Metabolism and Toxicity.

Bissig KD, Han W, Barzi M, Kovalchuk N, Ding L, Fan X, Pankowicz FP, Zhang QY, Ding X.

Drug Metab Dispos. 2018 Nov;46(11):1734-1744. doi: 10.1124/dmd.118.083303. Epub 2018 Aug 9.

PMID:
30093418
3.

Erratum: A novel humanized mouse lacking murine p450 oxidoreductase for studying human drug metabolism.

Barzi M, Pankowicz FP, Zorman B, Liu X, Legras X, Yang D, Borowiak M, Bissig-Choisat B, Sumazin P, Li F, Bissig KD.

Nat Commun. 2017 Oct 17;8(1):984. doi: 10.1038/s41467-017-01314-9.

4.

In Situ Liver Expression of HBsAg/CD3-Bispecific Antibodies for HBV Immunotherapy.

Kruse RL, Shum T, Legras X, Barzi M, Pankowicz FP, Gottschalk S, Bissig KD.

Mol Ther Methods Clin Dev. 2017 Aug 31;7:32-41. doi: 10.1016/j.omtm.2017.08.006. eCollection 2017 Dec 15.

5.

A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.

Barzi M, Pankowicz FP, Zorman B, Liu X, Legras X, Yang D, Borowiak M, Bissig-Choisat B, Sumazin P, Li F, Bissig KD.

Nat Commun. 2017 Jun 28;8(1):39. doi: 10.1038/s41467-017-00049-x. Erratum in: Nat Commun. 2017 Oct 17;8(1):984.

6.

CRISPR/Cas9: at the cutting edge of hepatology.

Pankowicz FP, Jarrett KE, Lagor WR, Bissig KD.

Gut. 2017 Jul;66(7):1329-1340. doi: 10.1136/gutjnl-2016-313565. Epub 2017 May 9. Review.

7.

Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia.

Pankowicz FP, Barzi M, Legras X, Hubert L, Mi T, Tomolonis JA, Ravishankar M, Sun Q, Yang D, Borowiak M, Sumazin P, Elsea SH, Bissig-Choisat B, Bissig KD.

Nat Commun. 2016 Aug 30;7:12642. doi: 10.1038/ncomms12642.

8.

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model.

Bissig-Choisat B, Wang L, Legras X, Saha PK, Chen L, Bell P, Pankowicz FP, Hill MC, Barzi M, Kettlun Leyton C, Leung HC, Kruse RL, Himes RW, Goss JA, Wilson JM, Chan L, Lagor WR, Bissig KD.

Nat Commun. 2015 Jun 17;6:7339. doi: 10.1038/ncomms8339.

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