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Items: 11


A network approach to exploring the functional basis of gene-gene epistatic interactions in disease susceptibility.

Yip DK, Chan LL, Pang IK, Jiang W, Tang NLS, Yu W, Yip KY.

Bioinformatics. 2018 May 15;34(10):1741-1749. doi: 10.1093/bioinformatics/bty005.


OMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps.

Li L, Leung AK, Kwok TP, Lai YYY, Pang IK, Chung GT, Mak ACY, Poon A, Chu C, Li M, Wu JJK, Lam ET, Cao H, Lin C, Sibert J, Yiu SM, Xiao M, Lo KW, Kwok PY, Chan TF, Yip KY.

Genome Biol. 2017 Dec 1;18(1):230. doi: 10.1186/s13059-017-1356-2.


AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity.

Schmid ET, Pang IK, Carrera Silva EA, Bosurgi L, Miner JJ, Diamond MS, Iwasaki A, Rothlin CV.

Elife. 2016 Jun 28;5. pii: e12414. doi: 10.7554/eLife.12414.


Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease.

Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, Staeheli P, Iwasaki A.

Science. 2016 Apr 22;352(6284):463-6. doi: 10.1126/science.aaf3926.


Efficient influenza A virus replication in the respiratory tract requires signals from TLR7 and RIG-I.

Pang IK, Pillai PS, Iwasaki A.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13910-5. doi: 10.1073/pnas.1303275110. Epub 2013 Aug 5.


IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8⁺ T cell responses to influenza A virus.

Pang IK, Ichinohe T, Iwasaki A.

Nat Immunol. 2013 Mar;14(3):246-53. doi: 10.1038/ni.2514. Epub 2013 Jan 13.


Control of antiviral immunity by pattern recognition and the microbiome.

Pang IK, Iwasaki A.

Immunol Rev. 2012 Jan;245(1):209-26. doi: 10.1111/j.1600-065X.2011.01073.x. Review.


Microbiota regulates immune defense against respiratory tract influenza A virus infection.

Ichinohe T, Pang IK, Kumamoto Y, Peaper DR, Ho JH, Murray TS, Iwasaki A.

Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5354-9. doi: 10.1073/pnas.1019378108. Epub 2011 Mar 14.


Inflammasomes as mediators of immunity against influenza virus.

Pang IK, Iwasaki A.

Trends Immunol. 2011 Jan;32(1):34-41. doi: 10.1016/ Epub 2010 Dec 14. Review.


Influenza virus activates inflammasomes via its intracellular M2 ion channel.

Ichinohe T, Pang IK, Iwasaki A.

Nat Immunol. 2010 May;11(5):404-10. doi: 10.1038/ni.1861. Epub 2010 Apr 11.

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