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Items: 1 to 50 of 337


Lipid-laden macrophages as biomarkers of vaping-associated lung injury.

Guerrini V, Panettieri RA Jr, Gennaro ML.

Lancet Respir Med. 2020 Feb;8(2):e6. doi: 10.1016/S2213-2600(19)30476-X. No abstract available.


The BJP expects authors to share data.

George CH, Alexander SPH, Cirino G, Docherty JR, Hoyer D, Insel PA, Izzo AA, Ji Y, Panettieri RA, Sobey CG, Stanford SC, Stefanska B, Stephens G, Teixeira M, Ahluwalia A.

Br J Pharmacol. 2019 Dec;176(24):4595-4598. doi: 10.1111/bph.14907. No abstract available.


Glucocorticoids rapidly activate cAMP production via Gαs to initiate non-genomic signaling that contributes to one-third of their canonical genomic effects.

Nuñez FJ, Johnstone TB, Corpuz ML, Kazarian AG, Mohajer NN, Tliba O, Panettieri RA Jr, Koziol-White C, Roosan MR, Ostrom RS.

FASEB J. 2020 Feb;34(2):2882-2895. doi: 10.1096/fj.201902521R. Epub 2019 Dec 27.


Budesonide enhances agonist-induced bronchodilation in human small airways by increasing cAMP production in airway smooth muscle.

Koziol-White C, Johnstone TB, Corpuz ML, Cao G, Orfanos S, Parikh V, Deeney B, Tliba O, Ostrom RS, Dainty I, Panettieri RA Jr.

Am J Physiol Lung Cell Mol Physiol. 2020 Feb 1;318(2):L345-L355. doi: 10.1152/ajplung.00393.2019. Epub 2019 Nov 20.


Revisiting John Snow to Meet the Challenge of Nontuberculous Mycobacterial Lung Disease.

Parikh A, Vinnard C, Fahrenfeld N, Davidow AL, Patrawalla A, Lardizabal A, Gow A, Panettieri R, Gennaro M.

Int J Environ Res Public Health. 2019 Nov 1;16(21). pii: E4250. doi: 10.3390/ijerph16214250. Review.


Bnip3 regulates airway smooth muscle cell focal adhesion and proliferation.

Pan S, Shah SD, Panettieri RA Jr, Deshpande DA.

Am J Physiol Lung Cell Mol Physiol. 2019 Dec 1;317(6):L758-L767. doi: 10.1152/ajplung.00224.2019. Epub 2019 Sep 11.


Diacylglycerol kinase ζ promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms.

Singh BK, Lu W, Schmidt Paustian AM, Ge MQ, Koziol-White CJ, Flayer CH, Killingbeck SS, Wang N, Dong X, Riese MJ, Deshpande DA, Panettieri RA Jr, Haczku A, Kambayashi T.

Sci Signal. 2019 Sep 3;12(597). pii: eaax3332. doi: 10.1126/scisignal.aax3332.


Soluble Guanylate Cyclase Agonists Induce Bronchodilation in Human Small Airways.

Koziol-White CJ, Ghosh A, Sandner P, Erzurum SE, Stuehr DJ, Panettieri RA Jr.

Am J Respir Cell Mol Biol. 2020 Jan;62(1):43-48. doi: 10.1165/rcmb.2019-0001OC.


A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm.

Kilic O, Yoon A, Shah SR, Yong HM, Ruiz-Valls A, Chang H, Panettieri RA Jr, Liggett SB, Quiñones-Hinojosa A, An SS, Levchenko A.

Nat Biomed Eng. 2019 Jul;3(7):532-544. doi: 10.1038/s41551-019-0366-7. Epub 2019 Mar 11.


Airway smooth muscle cells are insensitive to the anti-proliferative effects of corticosteroids: The novel role of insulin growth factor binding Protein-1 in asthma.

Bui H, Amrani Y, Deeney B, Panettieri RA, Tliba O.

Immunobiology. 2019 Jul;224(4):490-496. doi: 10.1016/j.imbio.2019.05.006. Epub 2019 May 23.


Publisher Correction: Elastomeric sensor surfaces for high-throughput single-cell force cytometry.

Pushkarsky I, Tseng P, Black D, France B, Warfe L, Koziol-White CJ, Jester WF Jr, Trinh RK, Lin J, Scumpia PO, Morrison SL, Panettieri RA Jr, Damoiseaux R, Di Carlo D.

Nat Biomed Eng. 2018 Apr;2(4):265. doi: 10.1038/s41551-018-0207-0.


Salicylic acid amplifies Carbachol-induced bronchoconstriction in human precision-cut lung slices.

Jude J, Botelho D, Karmacharya N, Cao GY, Jester W, Panettieri RA Jr.

Respir Res. 2019 Apr 11;20(1):72. doi: 10.1186/s12931-019-1034-x.


Guidelines for Developing a Radiologic Technology Course Syllabus.

Ortiz A, Panettieri R.

Radiol Technol. 2019 Mar;90(4):413-414. No abstract available.


Harmonized outcome measures for use in asthma patient registries and clinical practice.

Gliklich RE, Castro M, Leavy MB, Press VG, Barochia A, Carroll CL, Harris J, Rittner SS, Freishtat R, Panettieri RA Jr, Mosnaim GS.

J Allergy Clin Immunol. 2019 Sep;144(3):671-681.e1. doi: 10.1016/j.jaci.2019.02.025. Epub 2019 Mar 9.


Transforming Growth Factor-β1 Decreases β2-Agonist-induced Relaxation in Human Airway Smooth Muscle.

Ojiaku CA, Chung E, Parikh V, Williams JK, Schwab A, Fuentes AL, Corpuz ML, Lui V, Paek S, Bexiga NM, Narayan S, Nunez FJ, Ahn K, Ostrom RS, An SS, Panettieri RA Jr.

Am J Respir Cell Mol Biol. 2019 Aug;61(2):209-218. doi: 10.1165/rcmb.2018-0301OC.


Airway Smooth Muscle-Specific Transcriptomic Signatures of Glucocorticoid Exposure.

Kan M, Koziol-White C, Shumyatcher M, Johnson M, Jester W, Panettieri RA Jr, Himes BE.

Am J Respir Cell Mol Biol. 2019 Jul;61(1):110-120. doi: 10.1165/rcmb.2018-0385OC.


Modulation of Bronchomotor Tone Pathways in Airway Smooth Muscle Function and Bronchomotor Tone in Asthma.

Koziol-White CJ, Panettieri RA Jr.

Clin Chest Med. 2019 Mar;40(1):51-57. doi: 10.1016/j.ccm.2018.10.003. Epub 2018 Dec 19. Review.


CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen.

Duan S, Koziol-White CJ, Jester WF Jr, Nycholat CM, Macauley MS, Panettieri RA Jr, Paulson JC.

J Clin Invest. 2019 Mar 1;129(3):1387-1401. doi: 10.1172/JCI125456. Epub 2019 Feb 18.


Clinical Issues in Severe Asthma: Debates and Discussions About Personalizing Patient Management.

Panettieri RA Jr, Wechsler ME, Wenzel SE.

Chest. 2018 Dec;154(6):1459-1460. doi: 10.1016/j.chest.2018.09.002.


Non-genomic Effects of Glucocorticoids: An Updated View.

Panettieri RA, Schaafsma D, Amrani Y, Koziol-White C, Ostrom R, Tliba O.

Trends Pharmacol Sci. 2019 Jan;40(1):38-49. doi: 10.1016/ Epub 2018 Nov 26. Review.


Thank you and farewell after 15 years editing respiratory research.

Lotvall J, Panettieri RA Jr.

Respir Res. 2018 Nov 26;19(1):232. doi: 10.1186/s12931-018-0929-2. No abstract available.


Modulation of airway hyperresponsiveness by rhinovirus exposure.

Lo D, Kennedy JL, Kurten RC, Panettieri RA Jr, Koziol-White CJ.

Respir Res. 2018 Oct 29;19(1):208. doi: 10.1186/s12931-018-0914-9. Review.


Biased TAS2R Bronchodilators Inhibit Airway Smooth Muscle Growth by Downregulating Phosphorylated Extracellular Signal-regulated Kinase 1/2.

Kim D, Cho S, Castaño MA, Panettieri RA, Woo JA, Liggett SB.

Am J Respir Cell Mol Biol. 2019 May;60(5):532-540. doi: 10.1165/rcmb.2018-0189OC.


The Role of Neutrophils in Asthma.

Panettieri RA Jr.

Immunol Allergy Clin North Am. 2018 Nov;38(4):629-638. doi: 10.1016/j.iac.2018.06.005. Epub 2018 Sep 18. Review.


Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways.

Kennedy JL, Kurten RC, McCullough S, Panettieri RA, Koziol-White C, Jones SM, Caid K, Gill PS, Roberts D, Jaeschke H, McGill MR, James L.

Xenobiotica. 2019 Sep;49(9):1106-1115. doi: 10.1080/00498254.2018.1536814. Epub 2019 Jan 30.


Upregulated P-Rex1 exacerbates human airway smooth muscle hyperplasia in asthma.

Huang Y, Xie Y, Jiang H, Abel PW, Panettieri RA Jr, Casale TB, Tu Y.

J Allergy Clin Immunol. 2019 Feb;143(2):778-781.e5. doi: 10.1016/j.jaci.2018.09.020. Epub 2018 Oct 10. No abstract available.


Clinical Issues in Severe Asthma: Consensus and Controversies on the Road to Precision Medicine.

Bleecker ER, Panettieri RA Jr, Wenzel SE.

Chest. 2018 Oct;154(4):982-983. doi: 10.1016/j.chest.2018.08.1022.


Dexpramipexole depletes blood and tissue eosinophils in nasal polyps with no change in polyp size.

Laidlaw TM, Prussin C, Panettieri RA, Lee S, Ferguson BJ, Adappa ND, Lane AP, Palumbo ML, Sullivan M, Archibald D, Dworetzky SI, Hebrank GT, Bozik ME.

Laryngoscope. 2019 Feb;129(2):E61-E66. doi: 10.1002/lary.27564. Epub 2018 Oct 4.


How Important Is Adherence to Inhaled Medications Before Starting a Biologic Therapy for Asthma?

Corren J, Panettieri RA Jr.

J Allergy Clin Immunol Pract. 2018 Sep - Oct;6(5):1578-1579. doi: 10.1016/j.jaip.2018.07.007. No abstract available.


Obesity increases airway smooth muscle responses to contractile agonists.

Orfanos S, Jude J, Deeney BT, Cao G, Rastogi D, van Zee M, Pushkarsky I, Munoz HE, Damoiseaux R, Di Carlo D, Panettieri RA Jr.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L673-L681. doi: 10.1152/ajplung.00459.2017. Epub 2018 Aug 30.


Increased β2-adrenoceptor phosphorylation in airway smooth muscle in severe asthma: possible role of mast cell-derived growth factors.

Chachi L, Alzahrani A, Koziol-White C, Biddle M, Bagadood R, Panettieri RA Jr, Bradding P, Amrani Y.

Clin Exp Immunol. 2018 Nov;194(2):253-258. doi: 10.1111/cei.13191. Epub 2018 Sep 30.


Real-world Clinical Characteristics, Treatment Patterns, and Exacerbations in US Patients With Asthma Newly Treated With Omalizumab.

Ke X, Kavati A, Wertz D, Huang Q, Wang L, Willey VJ, Stephenson JJ, Ortiz B, Panettieri RA Jr,, Corren J.

Clin Ther. 2018 Jul;40(7):1140-1158.e4. doi: 10.1016/j.clinthera.2018.05.014. Epub 2018 Jul 23.


Regulator of G protein signaling 5 restricts neutrophil chemotaxis and trafficking.

Chan EC, Ren C, Xie Z, Jude J, Barker T, Koziol-White CA, Ma M, Panettieri RA Jr, Wu D, Rosenberg HF, Druey KM.

J Biol Chem. 2018 Aug 17;293(33):12690-12702. doi: 10.1074/jbc.RA118.002404. Epub 2018 Jun 21.


Paucigranulocytic asthma: Uncoupling of airway obstruction from inflammation.

Tliba O, Panettieri RA Jr.

J Allergy Clin Immunol. 2019 Apr;143(4):1287-1294. doi: 10.1016/j.jaci.2018.06.008. Epub 2018 Jun 19.


Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebo-controlled, phase 3 clinical trials.

Panettieri RA Jr, Sjöbring U, Péterffy A, Wessman P, Bowen K, Piper E, Colice G, Brightling CE.

Lancet Respir Med. 2018 Jul;6(7):511-525. doi: 10.1016/S2213-2600(18)30184-X. Epub 2018 May 20.


Molecular Tension Probes to Investigate the Mechanopharmacology of Single Cells: A Step toward Personalized Mechanomedicine.

Galior K, Ma VP, Liu Y, Su H, Baker N, Panettieri RA Jr, Wongtrakool C, Salaita K.

Adv Healthc Mater. 2018 Jul;7(14):e1800069. doi: 10.1002/adhm.201800069. Epub 2018 May 22.


Pepducins as a potential treatment strategy for asthma and COPD.

Panettieri RA, Pera T, Liggett SB, Benovic JL, Penn RB.

Curr Opin Pharmacol. 2018 Jun;40:120-125. doi: 10.1016/j.coph.2018.04.008. Epub 2018 May 2. Review.


Treatment of severe, uncontrolled eosinophilic asthma: Where we are heading.

Bernstein JA, Panettieri R Jr.

J Asthma. 2019 May;56(5):459-472. doi: 10.1080/02770903.2018.1471708. Epub 2018 Oct 16.


Tralokinumab for the treatment of severe, uncontrolled asthma: the ATMOSPHERE clinical development program.

Panettieri RA Jr, Wang M, Braddock M, Bowen K, Colice G.

Immunotherapy. 2018 Mar 1;10(6):473-490. doi: 10.2217/imt-2017-0191. Epub 2018 Mar 14. Review.


Elastomeric sensor surfaces for high-throughput single-cell force cytometry.

Pushkarsky I, Tseng P, Black D, France B, Warfe L, Koziol-White CJ, Jester WF Jr, Trinh RK, Lin J, Scumpia PO, Morrison SL, Panettieri RA Jr, Damoiseaux R, Di Carlo D.

Nat Biomed Eng. 2018 Feb;2(2):124-137. doi: 10.1038/s41551-018-0193-2. Epub 2018 Feb 6. Erratum in: Nat Biomed Eng. 2018 Apr;2(4):265.


Effects of rhinovirus 39 infection on airway hyperresponsiveness to carbachol in human airways precision cut lung slices.

Kennedy JL, Koziol-White CJ, Jeffus S, Rettiganti MR, Fisher P, Kurten M, Eze A, House S, Sikes JD, Askew E, Putt C, Panettieri RA, Jones SM, Kurten RC.

J Allergy Clin Immunol. 2018 May;141(5):1887-1890.e1. doi: 10.1016/j.jaci.2017.11.041. Epub 2018 Jan 6. No abstract available.



Erickson MA, Jude J, Zhao H, Rhea EM, Salameh TS, Jester W, Pu S, Harowitz J, Nguyen N, Banks WA, Panettieri RA Jr, Jordan-Sciutto KL.

FASEB J. 2018 Jan;32(1):535. doi: 10.1096/fj.201600857RRRERR. No abstract available.


Upregulation of Mas-related G Protein coupled receptor X2 in asthmatic lung mast cells and its activation by the novel neuropeptide hemokinin-1.

Manorak W, Idahosa C, Gupta K, Roy S, Panettieri R Jr, Ali H.

Respir Res. 2018 Jan 3;19(1):1. doi: 10.1186/s12931-017-0698-3.


PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2-Adrenergic Receptors and Adenylyl Cyclase 6.

Johnstone TB, Smith KH, Koziol-White CJ, Li F, Kazarian AG, Corpuz ML, Shumyatcher M, Ehlert FJ, Himes BE, Panettieri RA Jr, Ostrom RS.

Am J Respir Cell Mol Biol. 2018 Apr;58(4):530-541. doi: 10.1165/rcmb.2017-0294OC.


Synthetic Secoisolariciresinol Diglucoside (LGM2605) Protects Human Lung in an Ex Vivo Model of Proton Radiation Damage.

Velalopoulou A, Chatterjee S, Pietrofesa RA, Koziol-White C, Panettieri RA, Lin L, Tuttle S, Berman A, Koumenis C, Christofidou-Solomidou M.

Int J Mol Sci. 2017 Nov 25;18(12). pii: E2525. doi: 10.3390/ijms18122525.


Anti-IgE or Anti-IL5: That Is the Question.

Israel E, Panettieri RA Jr.

J Allergy Clin Immunol Pract. 2018 May - Jun;6(3):782-784. doi: 10.1016/j.jaip.2017.10.025. Epub 2017 Nov 14. No abstract available.


Guiding principles for use of newer biologics and bronchial thermoplasty for patients with severe asthma.

Blaiss MS, Castro M, Chipps BE, Zitt M, Panettieri RA Jr, Foggs MB.

Ann Allergy Asthma Immunol. 2017 Dec;119(6):533-540. doi: 10.1016/j.anai.2017.09.058. Epub 2017 Nov 2.


The Gulf Coast Health Alliance: Health Risks Related to the Macondo Spill (GC-HARMS) Study: Self-Reported Health Effects.

Croisant SA, Lin YL, Shearer JJ, Prochaska J, Phillips-Savoy A, Gee J, Jackson D, Panettieri RA, Howarth M, Sullivan J, Black BJ, Tate J, Nguyen D, Anthony A, Khan A, Fernando H, Ansari GAS, Rowe G, Howrey B, Singleton C, Elferink C.

Int J Environ Res Public Health. 2017 Oct 31;14(11). pii: E1328. doi: 10.3390/ijerph14111328.


Patient-reported outcomes in moderate-to-severe allergic asthmatics treated with omalizumab: a systematic literature review of randomized controlled trials.

Corren J, Kavati A, Ortiz B, Vegesna A, Colby JA, Ruiz K, Panettieri RA Jr.

Curr Med Res Opin. 2018 Jan;34(1):65-80. doi: 10.1080/03007995.2017.1395734. Epub 2017 Nov 10.


Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines.

Pera T, Deshpande DA, Ippolito M, Wang B, Gavrila A, Michael JV, Nayak AP, Tompkins E, Farrell E, Kroeze WK, Roth BL, Panettieri RA Jr, Benovic JL, An SS, Dulin NO, Penn RB.

FASEB J. 2018 Feb;32(2):862-874. doi: 10.1096/fj.201700555R. Epub 2018 Jan 4.

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