Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 88

1.

Complete Local and Abscopal Responses from a Combination of Radiation and Nivolumab in Refractory Hodgkin's Lymphoma.

Qin Q, Nan X, Miller T, Fisher R, Teh B, Pandita S, Farach AM, Pingali SR, Pandita RK, Butler EB, Pandita TK, Iyer SP.

Radiat Res. 2018 Sep;190(3):322-329. doi: 10.1667/RR15048.1. Epub 2018 Jun 27.

PMID:
29949442
2.

SMARCAD1 Phosphorylation and Ubiquitination Are Required for Resection during DNA Double-Strand Break Repair.

Chakraborty S, Pandita RK, Hambarde S, Mattoo AR, Charaka V, Ahmed KM, Iyer SP, Hunt CR, Pandita TK.

iScience. 2018 Apr 27;2:123-135. doi: 10.1016/j.isci.2018.03.016.

3.

Harnessing and Optimizing the Interplay between Immunotherapy and Radiotherapy to Improve Survival Outcomes.

Mujoo K, Hunt CR, Pandita RK, Ferrari M, Krishnan S, Cooke JP, Hahn S, Pandita TK.

Mol Cancer Res. 2018 Aug;16(8):1209-1214. doi: 10.1158/1541-7786.MCR-17-0743. Epub 2018 Mar 28. Review.

PMID:
29592896
4.

β1-Integrin Impacts Rad51 Stability and DNA Double-Strand Break Repair by Homologous Recombination.

Ahmed KM, Pandita RK, Singh DK, Hunt CR, Pandita TK.

Mol Cell Biol. 2018 Apr 16;38(9). pii: e00672-17. doi: 10.1128/MCB.00672-17. Print 2018 May 1.

5.

MOF Suppresses Replication Stress and Contributes to Resolution of Stalled Replication Forks.

Singh DK, Pandita RK, Singh M, Chakraborty S, Hambarde S, Ramnarain D, Charaka V, Ahmed KM, Hunt CR, Pandita TK.

Mol Cell Biol. 2018 Feb 27;38(6). pii: e00484-17. doi: 10.1128/MCB.00484-17. Print 2018 Mar 15.

6.

CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition.

Gadhikar MA, Zhang J, Shen L, Rao X, Wang J, Zhao M, Kalu NN, Johnson FM, Byers LA, Heymach J, Hittelman WN, Udayakumar D, Pandita RK, Pandita TK, Pickering CR, Redwood AB, Piwnica-Worms H, Schlacher K, Frederick MJ, Myers JN.

Cancer Res. 2018 Feb 1;78(3):781-797. doi: 10.1158/0008-5472.CAN-17-2802. Epub 2017 Dec 11.

PMID:
29229598
7.

Differentiation of Human Induced Pluripotent or Embryonic Stem Cells Decreases the DNA Damage Repair by Homologous Recombination.

Mujoo K, Pandita RK, Tiwari A, Charaka V, Chakraborty S, Singh DK, Hambarde S, Hittelman WN, Horikoshi N, Hunt CR, Khanna KK, Kots AY, Butler EB, Murad F, Pandita TK.

Stem Cell Reports. 2017 Nov 14;9(5):1660-1674. doi: 10.1016/j.stemcr.2017.10.002. Epub 2017 Nov 2.

8.

Erratum: miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin.

Patel N, Garikapati KR, Pandita RK, Singh DK, Pandita TK, Bhadra U, Bhadra MP.

Sci Rep. 2017 Oct 10;7(1):12932. doi: 10.1038/s41598-017-12314-6.

9.

Transcription regulation of CDKN1A (p21/CIP1/WAF1) by TRF2 is epigenetically controlled through the REST repressor complex.

Hussain T, Saha D, Purohit G, Kar A, Kishore Mukherjee A, Sharma S, Sengupta S, Dhapola P, Maji B, Vedagopuram S, Horikoshi NT, Horikoshi N, Pandita RK, Bhattacharya S, Bajaj A, Riou JF, Pandita TK, Chowdhury S.

Sci Rep. 2017 Sep 14;7(1):11541. doi: 10.1038/s41598-017-11177-1.

10.

miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin.

Patel N, Garikapati KR, Pandita RK, Singh DK, Pandita TK, Bhadra U, Bhadra MP.

Sci Rep. 2017 Jun 27;7(1):4263. doi: 10.1038/s41598-017-02800-2. Erratum in: Sci Rep. 2017 Oct 10;7(1):12932.

11.

Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis.

Wang H, Peng B, Pandita RK, Engler DA, Matsunami RK, Xu X, Hegde PM, Butler BE, Pandita TK, Mitra S, Xu B, Hegde ML.

Oncotarget. 2017 Jul 25;8(30):48671-48687. doi: 10.18632/oncotarget.16225.

12.

Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.

Shi W, Vu T, Boucher D, Biernacka A, Nde J, Pandita RK, Straube J, Boyle GM, Al-Ejeh F, Nag P, Jeffery J, Harris JL, Bain AL, Grzelak M, Skrzypczak M, Mitra A, Dojer N, Crosetto N, Cloonan N, Becherel OJ, Finnie J, Skaar JR, Walkley CR, Pandita TK, Rowicka M, Ginalski K, Lane SW, Khanna KK.

Blood. 2017 May 4;129(18):2479-2492. doi: 10.1182/blood-2016-06-725093. Epub 2017 Mar 7.

13.

MCL-1 Depletion Impairs DNA Double-Strand Break Repair and Reinitiation of Stalled DNA Replication Forks.

Mattoo AR, Pandita RK, Chakraborty S, Charaka V, Mujoo K, Hunt CR, Pandita TK.

Mol Cell Biol. 2017 Jan 19;37(3). pii: e00535-16. doi: 10.1128/MCB.00535-16. Print 2017 Feb 1.

14.

Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes.

Chakraborty A, Tapryal N, Venkova T, Horikoshi N, Pandita RK, Sarker AH, Sarkar PS, Pandita TK, Hazra TK.

Nat Commun. 2016 Oct 5;7:13049. doi: 10.1038/ncomms13049.

15.

Pluripotent Stem Cells and DNA Damage Response to Ionizing Radiations.

Mujoo K, Butler EB, Pandita RK, Hunt CR, Pandita TK.

Radiat Res. 2016 Jul;186(1):17-26. doi: 10.1667/RR14417.1. Epub 2016 Jun 22. Review.

16.

HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells.

Sadik H, Korangath P, Nguyen NK, Gyorffy B, Kumar R, Hedayati M, Teo WW, Park S, Panday H, Munoz TG, Menyhart O, Shah N, Pandita RK, Chang JC, DeWeese T, Chang HY, Pandita TK, Sukumar S.

Cancer Res. 2016 Aug 1;76(15):4443-56. doi: 10.1158/0008-5472.CAN-16-0774. Epub 2016 Jun 14.

17.

β2-spectrin depletion impairs DNA damage repair.

Horikoshi N, Pandita RK, Mujoo K, Hambarde S, Sharma D, Mattoo AR, Chakraborty S, Charaka V, Hunt CR, Pandita TK.

Oncotarget. 2016 Jun 7;7(23):33557-70. doi: 10.18632/oncotarget.9677.

18.

The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.

Jacquet K, Fradet-Turcotte A, Avvakumov N, Lambert JP, Roques C, Pandita RK, Paquet E, Herst P, Gingras AC, Pandita TK, Legube G, Doyon Y, Durocher D, Côté J.

Mol Cell. 2016 May 5;62(3):409-421. doi: 10.1016/j.molcel.2016.03.031.

19.

Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair.

Udayakumar D, Pandita RK, Horikoshi N, Liu Y, Liu Q, Wong KK, Hunt CR, Gray NS, Minna JD, Pandita TK, Westover KD.

Radiat Res. 2016 May;185(5):527-38. doi: 10.1667/RR14373.1. Epub 2016 May 2.

20.

ATM functions at the peroxisome to induce pexophagy in response to ROS.

Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL.

Nat Cell Biol. 2015 Oct;17(10):1259-1269. doi: 10.1038/ncb3230. Epub 2015 Sep 7.

21.

Role of the Exocyst Complex Component Sec6/8 in Genomic Stability.

Torres MJ, Pandita RK, Kulak O, Kumar R, Formstecher E, Horikoshi N, Mujoo K, Hunt CR, Zhao Y, Lum L, Zaman A, Yeaman C, White MA, Pandita TK.

Mol Cell Biol. 2015 Nov;35(21):3633-45. doi: 10.1128/MCB.00768-15. Epub 2015 Aug 17.

22.

Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation.

Chakraborty A, Wakamiya M, Venkova-Canova T, Pandita RK, Aguilera-Aguirre L, Sarker AH, Singh DK, Hosoki K, Wood TG, Sharma G, Cardenas V, Sarkar PS, Sur S, Pandita TK, Boldogh I, Hazra TK.

J Biol Chem. 2015 Oct 9;290(41):24636-48. doi: 10.1074/jbc.M115.658146. Epub 2015 Aug 5.

23.

Targeted inhibition of histone deacetylases and hedgehog signaling suppress tumor growth and homologous recombination in aerodigestive cancers.

Chun SG, Park H, Pandita RK, Horikoshi N, Pandita TK, Schwartz DL, Yordy JS.

Am J Cancer Res. 2015 Mar 15;5(4):1337-52. eCollection 2015.

24.

BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1.

Ge C, Che L, Ren J, Pandita RK, Lu J, Li K, Pandita TK, Du C.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1210-9. doi: 10.1073/pnas.1418335112. Epub 2015 Mar 2.

25.

The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.

Chatterjee A, Saha S, Chakraborty A, Silva-Fernandes A, Mandal SM, Neves-Carvalho A, Liu Y, Pandita RK, Hegde ML, Hegde PM, Boldogh I, Ashizawa T, Koeppen AH, Pandita TK, Maciel P, Sarkar PS, Hazra TK.

PLoS Genet. 2015 Jan 29;11(1):e1004749. doi: 10.1371/journal.pgen.1004749. eCollection 2015 Jan.

26.

Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs.

Pandita RK, Chow TT, Udayakumar D, Bain AL, Cubeddu L, Hunt CR, Shi W, Horikoshi N, Zhao Y, Wright WE, Khanna KK, Shay JW, Pandita TK.

Cancer Res. 2015 Mar 1;75(5):858-69. doi: 10.1158/0008-5472.CAN-14-2289. Epub 2015 Jan 14.

27.

MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice.

Gupta A, Hunt CR, Hegde ML, Chakraborty S, Chakraborty S, Udayakumar D, Horikoshi N, Singh M, Ramnarain DB, Hittelman WN, Namjoshi S, Asaithamby A, Hazra TK, Ludwig T, Pandita RK, Tyler JK, Pandita TK.

Cell Rep. 2014 Jul 10;8(1):177-89. doi: 10.1016/j.celrep.2014.05.044. Epub 2014 Jun 19. Erratum in: Cell Rep. 2014 Jul 10;8(1):319.

28.

Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.

Bolderson E, Petermann E, Croft L, Suraweera A, Pandita RK, Pandita TK, Helleday T, Khanna KK, Richard DJ.

Nucleic Acids Res. 2014 Jun;42(10):6326-36. doi: 10.1093/nar/gku276. Epub 2014 Apr 20.

29.

Role of 53BP1 in the regulation of DNA double-strand break repair pathway choice.

Gupta A, Hunt CR, Chakraborty S, Pandita RK, Yordy J, Ramnarain DB, Horikoshi N, Pandita TK.

Radiat Res. 2014 Jan;181(1):1-8. doi: 10.1667/RR13572.1. Epub 2013 Dec 9. Review.

30.

T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice.

Gupta A, Hunt CR, Pandita RK, Pae J, Komal K, Singh M, Shay JW, Kumar R, Ariizumi K, Horikoshi N, Hittelman WN, Guha C, Ludwig T, Pandita TK.

Mutagenesis. 2013 May;28(3):263-70. doi: 10.1093/mutage/ges080. Epub 2013 Feb 5.

31.

Histone modifications and DNA double-strand break repair after exposure to ionizing radiations.

Hunt CR, Ramnarain D, Horikoshi N, Iyengar P, Pandita RK, Shay JW, Pandita TK.

Radiat Res. 2013 Apr;179(4):383-92. doi: 10.1667/RR3308.2. Epub 2013 Feb 1. Review.

32.

Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest.

Singh M, Hunt CR, Pandita RK, Kumar R, Yang CR, Horikoshi N, Bachoo R, Serag S, Story MD, Shay JW, Powell SN, Gupta A, Jeffery J, Pandita S, Chen BP, Deckbar D, Löbrich M, Yang Q, Khanna KK, Worman HJ, Pandita TK.

Mol Cell Biol. 2013 Mar;33(6):1210-22. doi: 10.1128/MCB.01676-12. Epub 2013 Jan 14. Erratum in: Mol Cell Biol. 2013 Aug;33(16):3390.

33.

Targeting of Nrf2 induces DNA damage signaling and protects colonic epithelial cells from ionizing radiation.

Kim SB, Pandita RK, Eskiocak U, Ly P, Kaisani A, Kumar R, Cornelius C, Wright WE, Pandita TK, Shay JW.

Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):E2949-55. doi: 10.1073/pnas.1207718109. Epub 2012 Oct 8.

34.

Inhibition of heat shock transcription factor binding by a linear polyamide binding in an unusual 1:1 mode.

Wang RE, Pandita RK, Cai J, Hunt CR, Taylor JS.

Chembiochem. 2012 Jan 2;13(1):97-104. doi: 10.1002/cbic.201100524. Epub 2011 Dec 1.

35.

The role of MOF in the ionizing radiation response is conserved in Drosophila melanogaster.

Bhadra MP, Horikoshi N, Pushpavallipvalli SN, Sarkar A, Bag I, Krishnan A, Lucchesi JC, Kumar R, Yang Q, Pandita RK, Singh M, Bhadra U, Eissenberg JC, Pandita TK.

Chromosoma. 2012 Feb;121(1):79-90. doi: 10.1007/s00412-011-0344-7. Epub 2011 Nov 10.

36.

Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice.

Kumar R, Hunt CR, Gupta A, Nannepaga S, Pandita RK, Shay JW, Bachoo R, Ludwig T, Burns DK, Pandita TK.

Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3636-41. doi: 10.1073/pnas.1016524108. Epub 2011 Feb 14.

37.

MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair.

Sharma GG, So S, Gupta A, Kumar R, Cayrou C, Avvakumov N, Bhadra U, Pandita RK, Porteus MH, Chen DJ, Cote J, Pandita TK.

Mol Cell Biol. 2010 Jul;30(14):3582-95. doi: 10.1128/MCB.01476-09. Epub 2010 May 17.

38.

Severe, short-duration (0-3 min) heat shocks (50-52 degrees C) inhibit the repair of DNA damage.

Roti Roti JL, Pandita RK, Mueller JD, Novak P, Moros EG, Laszlo A.

Int J Hyperthermia. 2010 Feb;26(1):67-78. doi: 10.3109/02656730903417947.

PMID:
20100054
39.

Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair.

Gupta A, Yang Q, Pandita RK, Hunt CR, Xiang T, Misri S, Zeng S, Pagan J, Jeffery J, Puc J, Kumar R, Feng Z, Powell SN, Bhat A, Yaguchi T, Wadhwa R, Kaul SC, Parsons R, Khanna KK, Pandita TK.

Cell Cycle. 2009 Jul 15;8(14):2198-210. Epub 2009 Jul 7.

PMID:
19502790
40.

Inhibition of heat shock induction of heat shock protein 70 and enhancement of heat shock protein 27 phosphorylation by quercetin derivatives.

Wang RE, Kao JL, Hilliard CA, Pandita RK, Roti Roti JL, Hunt CR, Taylor JS.

J Med Chem. 2009 Apr 9;52(7):1912-21. doi: 10.1021/jm801445c.

41.

HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions.

Aucott R, Bullwinkel J, Yu Y, Shi W, Billur M, Brown JP, Menzel U, Kioussis D, Wang G, Reisert I, Weimer J, Pandita RK, Sharma GG, Pandita TK, Fundele R, Singh PB.

J Cell Biol. 2008 Nov 17;183(4):597-606. doi: 10.1083/jcb.200804041.

42.

Role for proteasome activator PA200 and postglutamyl proteasome activity in genomic stability.

Blickwedehl J, Agarwal M, Seong C, Pandita RK, Melendy T, Sung P, Pandita TK, Bangia N.

Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16165-70. doi: 10.1073/pnas.0803145105. Epub 2008 Oct 9.

43.

Inhibition of telomerase activity enhances hyperthermia-mediated radiosensitization.

Agarwal M, Pandita S, Hunt CR, Gupta A, Yue X, Khan S, Pandita RK, Pratt D, Shay JW, Taylor JS, Pandita TK.

Cancer Res. 2008 May 1;68(9):3370-8. doi: 10.1158/0008-5472.CAN-07-5831.

44.

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.

Richard DJ, Bolderson E, Cubeddu L, Wadsworth RI, Savage K, Sharma GG, Nicolette ML, Tsvetanov S, McIlwraith MJ, Pandita RK, Takeda S, Hay RT, Gautier J, West SC, Paull TT, Pandita TK, White MF, Khanna KK.

Nature. 2008 May 29;453(7195):677-81. doi: 10.1038/nature06883. Epub 2008 Apr 30.

PMID:
18449195
45.

Pharmacological characterization of a novel investigational antimuscarinic drug, fesoterodine, in vitro and in vivo.

Ney P, Pandita RK, Newgreen DT, Breidenbach A, Stöhr T, Andersson KE.

BJU Int. 2008 Apr;101(8):1036-42. doi: 10.1111/j.1464-410X.2007.07358.x. Epub 2008 Feb 15.

46.

The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis.

Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK.

Mol Cell Biol. 2008 Jan;28(1):397-409. Epub 2007 Oct 29.

47.

Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status.

Hunt CR, Pandita RK, Laszlo A, Higashikubo R, Agarwal M, Kitamura T, Gupta A, Rief N, Horikoshi N, Baskaran R, Lee JH, Löbrich M, Paull TT, Roti Roti JL, Pandita TK.

Cancer Res. 2007 Apr 1;67(7):3010-7.

48.

A role for the HOXB7 homeodomain protein in DNA repair.

Rubin E, Wu X, Zhu T, Cheung JC, Chen H, Lorincz A, Pandita RK, Sharma GG, Ha HC, Gasson J, Hanakahi LA, Pandita TK, Sukumar S.

Cancer Res. 2007 Feb 15;67(4):1527-35.

50.

Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair.

Pandita RK, Sharma GG, Laszlo A, Hopkins KM, Davey S, Chakhparonian M, Gupta A, Wellinger RJ, Zhang J, Powell SN, Roti Roti JL, Lieberman HB, Pandita TK.

Mol Cell Biol. 2006 Mar;26(5):1850-64.

Supplemental Content

Loading ...
Support Center