Format
Sort by

Send to

Choose Destination

Search results

Items: 5

1.

Pharmacokinetics of IDX184, a liver-targeted oral prodrug of 2'-methylguanosine-5'-monophosphate, in the monkey and formulation optimization for human exposure.

Pan-Zhou XR, Mayes BA, Rashidzadeh H, Gasparac R, Smith S, Bhadresa S, Gupta K, Cohen ML, Bu C, Good SS, Moussa A, Rush R.

Eur J Drug Metab Pharmacokinet. 2016 Oct;41(5):567-74. doi: 10.1007/s13318-015-0267-4. Epub 2015 Apr 22.

PMID:
25898809
2.

Differential effects of antiretroviral nucleoside analogs on mitochondrial function in HepG2 cells.

Pan-Zhou XR, Cui L, Zhou XJ, Sommadossi JP, Darley-Usmar VM.

Antimicrob Agents Chemother. 2000 Mar;44(3):496-503.

3.

Role of human liver P450s and cytochrome b5 in the reductive metabolism of 3'-azido-3'-deoxythymidine (AZT) to 3'-amino-3'-deoxythymidine.

Pan-Zhou XR, Cretton-Scott E, Zhou XJ, Yang MX, Lasker JM, Sommadossi JP.

Biochem Pharmacol. 1998 Mar 15;55(6):757-66.

PMID:
9586947
4.

Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes.

Pan-Zhou XR, Cretton-Scott E, Zhou XJ, Xie MY, Rahmani R, Schinazi RF, Duchin K, Sommadossi JP.

Antimicrob Agents Chemother. 1997 Nov;41(11):2502-10.

5.

Phase I dose-escalation pharmacokinetics of AZT-P-ddI (IVX-E-59) in patients with human immunodeficiency virus.

Zhou XJ, Squires K, Pan-Zhou XR, Bernhard S, Agrofoglio L, Kirk M, Duchin KL, Sommadossi JP.

J Clin Pharmacol. 1997 Mar;37(3):201-13.

PMID:
9089422

Supplemental Content

Loading ...
Support Center