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Items: 27


Digital Microfluidic Platform to Maximize Diagnostic Tests with Low Sample Volumes from Newborns and Pediatric Patients.

Sista RS, Ng R, Nuffer M, Basmajian M, Coyne J, Elderbroom J, Hull D, Kay K, Krishnamurthy M, Roberts C, Wu D, Kennedy AD, Singh R, Srinivasan V, Pamula VK.

Diagnostics (Basel). 2020 Jan 1;10(1). pii: E21. doi: 10.3390/diagnostics10010021.


A 0.0023 mm2/ch. Delta-Encoded, Time-Division Multiplexed Mixed-Signal ECoG Recording Architecture with Stimulus Artifact Suppression.

Uehlin JP, Smith WA, Pamula VR, Perlmutter S, Rudell JC, Sathe VS.

IEEE Trans Biomed Circuits Syst. 2019 Dec 31. doi: 10.1109/TBCAS.2019.2963174. [Epub ahead of print]


Fluorimetric assay with a novel substrate for quantification of galactocerebrosidase activity in dried blood spot specimens.

Ullal AJ, Pham H, Singh R, Ross P, Graham CA, Norton SM, Nuffer MH, Burns DS, Eckhardt AE, Escolar M, Bali D, Pamula VK.

Pract Lab Med. 2019 Oct 16;18:e00141. doi: 10.1016/j.plabm.2019.e00141. eCollection 2020 Jan.


Digital microfluidics comes of age: high-throughput screening to bedside diagnostic testing for genetic disorders in newborns.

Millington D, Norton S, Singh R, Sista R, Srinivasan V, Pamula V.

Expert Rev Mol Diagn. 2018 Aug;18(8):701-712. doi: 10.1080/14737159.2018.1495076. Epub 2018 Jul 13.


Enzymatic Functional Assays of Coagulation Using Small Sample Volumes.

Emani S, Nelson LT, Norton S, Singh R, Pamula V, Emani S.

Lab Med. 2017 Dec 22;49(1):47-54. doi: 10.1093/labmed/lmx067.


A 172 $\mu$W Compressively Sampled Photoplethysmographic (PPG) Readout ASIC With Heart Rate Estimation Directly From Compressively Sampled Data.

Pamula VR, Valero-Sarmiento JM, Yan L, Bozkurt A, Hoof CV, Helleputte NV, Yazicioglu RF, Verhelst M.

IEEE Trans Biomed Circuits Syst. 2017 Jun;11(3):487-496. doi: 10.1109/TBCAS.2017.2661701. Epub 2017 May 19.


Point-of-Care Quantitative Measure of Glucose-6-Phosphate Dehydrogenase Enzyme Deficiency.

Bhutani VK, Kaplan M, Glader B, Cotten M, Kleinert J, Pamula V.

Pediatrics. 2015 Nov;136(5):e1268-75. doi: 10.1542/peds.2015-2122. Epub 2015 Oct 12.


The dynamics and stability of lubricating oil films during droplet transport by electrowetting in microfluidic devices.

Kleinert J, Srinivasan V, Rival A, Delattre C, Velev OD, Pamula VK.

Biomicrofluidics. 2015 May 19;9(3):034104. doi: 10.1063/1.4921489. eCollection 2015 May.


A 680 nA ECG acquisition IC for leadless pacemaker applications.

Yan L, Harpe P, Pamula VR, Osawa M, Harada Y, Tamiya K, Van Hoof C, Yazicioglu RF.

IEEE Trans Biomed Circuits Syst. 2014 Dec;8(6):779-86. doi: 10.1109/TBCAS.2014.2377073. Epub 2014 Dec 24.


Novel application of digital microfluidics for the detection of biotinidase deficiency in newborns.

Graham C, Sista RS, Kleinert J, Wu N, Eckhardt A, Bali D, Millington DS, Pamula VK.

Clin Biochem. 2013 Dec;46(18):1889-91. doi: 10.1016/j.clinbiochem.2013.09.003. Epub 2013 Sep 11.


Multiplex newborn screening for Pompe, Fabry, Hunter, Gaucher, and Hurler diseases using a digital microfluidic platform.

Sista RS, Wang T, Wu N, Graham C, Eckhardt A, Winger T, Srinivasan V, Bali D, Millington DS, Pamula VK.

Clin Chim Acta. 2013 Sep 23;424:12-8. doi: 10.1016/j.cca.2013.05.001. Epub 2013 May 7.


Rapid assays for Gaucher and Hurler diseases in dried blood spots using digital microfluidics.

Sista RS, Wang T, Wu N, Graham C, Eckhardt A, Bali D, Millington DS, Pamula VK.

Mol Genet Metab. 2013 Jun;109(2):218-20. doi: 10.1016/j.ymgme.2013.03.010. Epub 2013 Mar 24.


Novel microfluidic platform for automated lab-on-chip testing of hypercoagulability panel.

Emani S, Sista R, Loyola H, Trenor CC 3rd, Pamula VK, Emani SM.

Blood Coagul Fibrinolysis. 2012 Dec;23(8):760-8. doi: 10.1097/MBC.0b013e328358e982.


Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood.

Schell WA, Benton JL, Smith PB, Poore M, Rouse JL, Boles DJ, Johnson MD, Alexander BD, Pamula VK, Eckhardt AE, Pollack MG, Benjamin DK Jr, Perfect JR, Mitchell TG.

Eur J Clin Microbiol Infect Dis. 2012 Sep;31(9):2237-45. doi: 10.1007/s10096-012-1561-6. Epub 2012 Feb 11.


A novel fluorometric enzyme analysis method for Hunter syndrome using dried blood spots.

Tolun AA, Graham C, Shi Q, Sista RS, Wang T, Eckhardt AE, Pamula VK, Millington DS, Bali DS.

Mol Genet Metab. 2012 Mar;105(3):519-21. doi: 10.1016/j.ymgme.2011.12.011. Epub 2011 Dec 21.


Droplet-based pyrosequencing using digital microfluidics.

Boles DJ, Benton JL, Siew GJ, Levy MH, Thwar PK, Sandahl MA, Rouse JL, Perkins LC, Sudarsan AP, Jalili R, Pamula VK, Srinivasan V, Fair RB, Griffin PB, Eckhardt AE, Pollack MG.

Anal Chem. 2011 Nov 15;83(22):8439-47. doi: 10.1021/ac201416j. Epub 2011 Oct 14.


Digital microfluidic platform for multiplexing enzyme assays: implications for lysosomal storage disease screening in newborns.

Sista RS, Eckhardt AE, Wang T, Graham C, Rouse JL, Norton SM, Srinivasan V, Pollack MG, Tolun AA, Bali D, Millington DS, Pamula VK.

Clin Chem. 2011 Oct;57(10):1444-51. doi: 10.1373/clinchem.2011.163139. Epub 2011 Aug 22.


Rapid, single-step assay for Hunter syndrome in dried blood spots using digital microfluidics.

Sista R, Eckhardt AE, Wang T, Séllos-Moura M, Pamula VK.

Clin Chim Acta. 2011 Sep 18;412(19-20):1895-7. doi: 10.1016/j.cca.2011.06.015. Epub 2011 Jun 17. No abstract available.


Applications of electrowetting-based digital microfluidics in clinical diagnostics.

Pollack MG, Pamula VK, Srinivasan V, Eckhardt AE.

Expert Rev Mol Diagn. 2011 May;11(4):393-407. doi: 10.1586/erm.11.22. Review.


Microfluidic platform versus conventional real-time polymerase chain reaction for the detection of Mycoplasma pneumoniae in respiratory specimens.

Wulff-Burchfield E, Schell WA, Eckhardt AE, Pollack MG, Hua Z, Rouse JL, Pamula VK, Srinivasan V, Benton JL, Alexander BD, Wilfret DA, Kraft M, Cairns CB, Perfect JR, Mitchell TG.

Diagn Microbiol Infect Dis. 2010 May;67(1):22-9. doi: 10.1016/j.diagmicrobio.2009.12.020. Epub 2010 Mar 12.


Digital microfluidics: a future technology in the newborn screening laboratory?

Millington DS, Sista R, Eckhardt A, Rouse J, Bali D, Goldberg R, Cotten M, Buckley R, Pamula V.

Semin Perinatol. 2010 Apr;34(2):163-9. doi: 10.1053/j.semperi.2009.12.008.


Multiplexed real-time polymerase chain reaction on a digital microfluidic platform.

Hua Z, Rouse JL, Eckhardt AE, Srinivasan V, Pamula VK, Schell WA, Benton JL, Mitchell TG, Pollack MG.

Anal Chem. 2010 Mar 15;82(6):2310-6. doi: 10.1021/ac902510u.


Heterogeneous immunoassays using magnetic beads on a digital microfluidic platform.

Sista RS, Eckhardt AE, Srinivasan V, Pollack MG, Palanki S, Pamula VK.

Lab Chip. 2008 Dec;8(12):2188-96. doi: 10.1039/b807855f. Epub 2008 Oct 14.


Development of a digital microfluidic platform for point of care testing.

Sista R, Hua Z, Thwar P, Sudarsan A, Srinivasan V, Eckhardt A, Pollack M, Pamula V.

Lab Chip. 2008 Dec;8(12):2091-104. doi: 10.1039/b814922d. Epub 2008 Nov 5.


An integrated digital microfluidic lab-on-a-chip for clinical diagnostics on human physiological fluids.

Srinivasan V, Pamula VK, Fair RB.

Lab Chip. 2004 Aug;4(4):310-5. Epub 2004 May 26.


Electrowetting-based droplet mixers for microfluidic systems.

Paik P, Pamula VK, Pollack MG, Fair RB.

Lab Chip. 2003 Feb;3(1):28-33. Epub 2003 Feb 3.


Rapid droplet mixers for digital microfluidic systems.

Paik P, Pamula VK, Fair RB.

Lab Chip. 2003 Nov;3(4):253-9. Epub 2003 Sep 12.


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