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Items: 1 to 50 of 201

1.

Lipid profile of cerebrospinal fluid in multiple sclerosis patients: a potential tool for diagnosis.

Nogueras L, Gonzalo H, Jové M, Sol J, Gil-Sanchez A, Hervás JV, Valcheva P, Gonzalez-Mingot C, Solana MJ, Peralta S, Pamplona R, Brieva L.

Sci Rep. 2019 Aug 5;9(1):11313. doi: 10.1038/s41598-019-47906-x.

2.

Dissimilar Impact of a Mediterranean Diet and Physical Activity on Anthropometric Indices: A Cross-Sectional Study from the ILERVAS Project.

Sánchez M, Sánchez E, Hernández M, González J, Purroy F, Rius F, Pamplona R, Farràs-Sallés C, Gutiérrez-Carrasquilla L, Fernández E, Bermúdez-López M, Salvador J, Salas-Salvadó J, Lecube A; ILERVAS project collaborators.

Nutrients. 2019 Jun 17;11(6). pii: E1359. doi: 10.3390/nu11061359.

3.

A prospective pilot study using metabolomics discloses specific fatty acid, catecholamine and tryptophan metabolic pathways as possible predictors for a negative outcome after severe trauma.

Servià L, Jové M, Sol J, Pamplona R, Badia M, Montserrat N, Portero-Otin M, Trujillano J.

Scand J Trauma Resusc Emerg Med. 2019 May 22;27(1):56. doi: 10.1186/s13049-019-0631-5.

4.

Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study.

Casasnovas C, Ruiz M, Schlüter A, Naudí A, Fourcade S, Veciana M, Castañer S, Albertí A, Bargalló N, Johnson M, Raymond GV, Fatemi A, Moser AB, Villarroya F, Portero-Otín M, Artuch R, Pamplona R, Pujol A.

Neurotherapeutics. 2019 May 10. doi: 10.1007/s13311-019-00735-2. [Epub ahead of print]

PMID:
31077039
5.

Mediterranean diet, physical activity and subcutaneous advanced glycation end-products' accumulation: a cross-sectional analysis in the ILERVAS project.

Sánchez E, Betriu À, Salas-Salvadó J, Pamplona R, Barbé F, Purroy F, Farràs C, Fernández E, López-Cano C, Mizab C, Lecube A; ILERVAS project investigators.

Eur J Nutr. 2019 May 7. doi: 10.1007/s00394-019-01983-w. [Epub ahead of print]

PMID:
31065845
6.

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease.

Hernández-Alvarez MI, Sebastián D, Vives S, Ivanova S, Bartoccioni P, Kakimoto P, Plana N, Veiga SR, Hernández V, Vasconcelos N, Peddinti G, Adrover A, Jové M, Pamplona R, Gordaliza-Alaguero I, Calvo E, Cabré N, Castro R, Kuzmanic A, Boutant M, Sala D, Hyotylainen T, Orešič M, Fort J, Errasti-Murugarren E, Rodrígues CMP, Orozco M, Joven J, Cantó C, Palacin M, Fernández-Veledo S, Vendrell J, Zorzano A.

Cell. 2019 May 2;177(4):881-895.e17. doi: 10.1016/j.cell.2019.04.010.

PMID:
31051106
7.

Lung function measurements in the prediabetes stage: data from the ILERVAS Project.

Sánchez E, Gutiérrez-Carrasquilla L, Barbé F, Betriu À, López-Cano C, Gaeta AM, Purroy F, Pamplona R, Ortega M, Fernández E, Hernández C, Lecube A, Simó R; ILERVAS Project.

Acta Diabetol. 2019 Sep;56(9):1005-1012. doi: 10.1007/s00592-019-01333-6. Epub 2019 Apr 15.

PMID:
30989377
8.

Redox lipidomics to better understand brain aging and function.

Pamplona R, Borras C, Jové M, Pradas I, Ferrer I, Viña J.

Free Radic Biol Med. 2019 Mar 18. pii: S0891-5849(19)30077-2. doi: 10.1016/j.freeradbiomed.2019.03.016. [Epub ahead of print] Review.

PMID:
30898667
9.

[De novo biosynthesis of glycerophospholipids and longevity].

Mota-Martorell N, Pradas I, Jové M, Naudí A, Pamplona R.

Rev Esp Geriatr Gerontol. 2019 Mar - Apr;54(2):88-93. doi: 10.1016/j.regg.2018.05.006. Epub 2018 Jul 4. Spanish.

PMID:
30879491
10.

Skin Autofluorescence Measurement in Subclinical Atheromatous Disease: Results from the ILERVAS Project.

Sánchez E, Betriu À, Yeramian A, Fernández E, Purroy F, Sánchez-de-la-Torre M, Pamplona R, Miquel E, Kerkeni M, Hernández C, Simó R, Lecube A; ILERVAS project; ILERVAS Project:, Hernández M, Rius F, Polanco D, Barbé F, Torres G, Suárez G, Portero-Otin M, Jové M, Colàs-Campàs L, Benabdelhak I, Farràs C, Ortega M, Manuel Valdivielso J, Bermúdez-López M, Martínez-Alonso M.

J Atheroscler Thromb. 2019 Mar 6. doi: 10.5551/jat.47498. [Epub ahead of print]

11.

Effects of Mediterranean Diet and Physical Activity on Pulmonary Function: A Cross-Sectional Analysis in the ILERVAS Project.

Gutiérrez-Carrasquilla L, Sánchez E, Hernández M, Polanco D, Salas-Salvadó J, Betriu À, Gaeta AM, Carmona P, Purroy F, Pamplona R, Farràs C, López-Cano C, Fernández E, Lecube A.

Nutrients. 2019 Feb 3;11(2). pii: E329. doi: 10.3390/nu11020329.

12.

Exceptional human longevity is associated with a specific plasma phenotype of ether lipids.

Pradas I, Jové M, Huynh K, Puig J, Ingles M, Borras C, Viña J, Meikle PJ, Pamplona R.

Redox Biol. 2019 Feb;21:101127. doi: 10.1016/j.redox.2019.101127. Epub 2019 Jan 29.

13.

Influence of exposure and vertical transmission of HIV-1 on the neuropsychomotor development in children.

Pamplona MCDCA, Chaves EC, Carvalho AC, Pamplona RDCA, Vallinoto ACR, Queiroz MAF, Lima SS, Ishak R.

Rev Soc Bras Med Trop. 2019 Jan 14;52:e20180263. doi: 10.1590/0037-8682-0263-2018.

14.

Lipids and lipoxidation in human brain aging. Mitochondrial ATP-synthase as a key lipoxidation target.

Jové M, Pradas I, Dominguez-Gonzalez M, Ferrer I, Pamplona R.

Redox Biol. 2018 Dec 19:101082. doi: 10.1016/j.redox.2018.101082. [Epub ahead of print] Review.

15.

The cirrhotic liver is depleted of docosahexaenoic acid (DHA), a key modulator of NF-κB and TGFβ pathways in hepatic stellate cells.

Enguita M, Razquin N, Pamplona R, Quiroga J, Prieto J, Fortes P.

Cell Death Dis. 2019 Jan 8;10(1):14. doi: 10.1038/s41419-018-1243-0.

16.

Location-dependent effects of trauma on oxidative stress in humans.

Servia L, Serrano JCE, Pamplona R, Badia M, Montserrat N, Portero-Otin M, Trujillano J.

PLoS One. 2018 Oct 11;13(10):e0205519. doi: 10.1371/journal.pone.0205519. eCollection 2018.

17.

Lipidomics Reveals a Tissue-Specific Fingerprint.

Pradas I, Huynh K, Cabré R, Ayala V, Meikle PJ, Jové M, Pamplona R.

Front Physiol. 2018 Aug 28;9:1165. doi: 10.3389/fphys.2018.01165. eCollection 2018.

18.

Regional vulnerability to lipoxidative damage and inflammation in normal human brain aging.

Domínguez-González M, Puigpinós M, Jové M, Naudi A, Portero-Otín M, Pamplona R, Ferrer I.

Exp Gerontol. 2018 Oct 1;111:218-228. doi: 10.1016/j.exger.2018.07.023. Epub 2018 Aug 2.

PMID:
30077575
19.

Aberrant regulation of the GSK-3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy.

Ranea-Robles P, Launay N, Ruiz M, Calingasan NY, Dumont M, Naudí A, Portero-Otín M, Pamplona R, Ferrer I, Beal MF, Fourcade S, Pujol A.

EMBO Mol Med. 2018 Aug;10(8). pii: e8604. doi: 10.15252/emmm.201708604.

20.

Essential physiological differences characterise short- and long-lived strains of Drosophila melanogaster.

Gubina N, Naudi A, Stefanatos R, Jove M, Scialo F, Fernandez-Ayala DJ, Rantapero T, Yurkevych I, Portero-Otin M, Nykter M, Lushchak O, Navas P, Pamplona R, Sanz A.

J Gerontol A Biol Sci Med Sci. 2018 Jun 26. doi: 10.1093/gerona/gly143. [Epub ahead of print]

PMID:
29945183
21.

Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue.

Torres P, Ramírez-Núñez O, Romero-Guevara R, Barés G, Granado-Serrano AB, Ayala V, Boada J, Fontdevila L, Povedano M, Sanchís D, Pamplona R, Ferrer I, Portero-Otín M.

Autophagy. 2018;14(8):1398-1403. doi: 10.1080/15548627.2018.1474311. Epub 2018 Jul 28.

22.

Subcutaneous advanced glycation end-products and lung function according to glucose abnormalities: The ILERVAS Project.

Sánchez E, Lecube A, Betriu À, Hernández C, López-Cano C, Gutiérrez-Carrasquilla L, Kerkeni M, Yeramian A, Purroy F, Pamplona R, Farràs C, Fernández E, Barbé F, Simó R; ILERVAS project, Hernández M, Rius F, Polanco D, de la Torre MS, Torres G, Godoy P, Portero-Otin M, Jové M, Colàs-Compàs L, Benabdelhak I, Miquel E, Ortega M, Valdivielso JM, Bermúdez M, Martínez-Alonso M.

Diabetes Metab. 2018 Apr 13. pii: S1262-3636(18)30079-X. doi: 10.1016/j.diabet.2018.04.002. [Epub ahead of print] No abstract available.

PMID:
29706471
23.

Lipidomics reveals altered biosynthetic pathways of glycerophospholipids and cell signaling as biomarkers of the polycystic ovary syndrome.

Jové M, Pradas I, Naudí A, Rovira-Llopis S, Bañuls C, Rocha M, Portero-Otin M, Hernández-Mijares A, Victor VM, Pamplona R.

Oncotarget. 2017 Dec 17;9(4):4522-4536. doi: 10.18632/oncotarget.23393. eCollection 2018 Jan 12.

24.

Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients.

Eritja N, Jové M, Fasmer KE, Gatius S, Portero-Otin M, Trovik J, Krakstad C, Sol J, Pamplona R, Haldorsen IS, Matias-Guiu X.

Oncotarget. 2017 Nov 20;8(65):109018-109026. doi: 10.18632/oncotarget.22558. eCollection 2017 Dec 12.

25.

Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance.

Fourcade S, Morató L, Parameswaran J, Ruiz M, Ruiz-Cortés T, Jové M, Naudí A, Martínez-Redondo P, Dierssen M, Ferrer I, Villarroya F, Pamplona R, Vaquero A, Portero-Otín M, Pujol A.

Aging Cell. 2017 Dec;16(6):1404-1413. doi: 10.1111/acel.12682. Epub 2017 Oct 5.

26.

Lipid Profile in Human Frontal Cortex Is Sustained Throughout Healthy Adult Life Span to Decay at Advanced Ages.

Cabré R, Naudí A, Dominguez-Gonzalez M, Jové M, Ayala V, Mota-Martorell N, Pradas I, Nogueras L, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

J Gerontol A Biol Sci Med Sci. 2018 May 9;73(6):703-710. doi: 10.1093/gerona/glx164.

PMID:
28958038
27.

Differential metabolic profiles associated to movement behaviour of stream-resident brown trout (Salmo trutta).

Oromi N, Jové M, Pascual-Pons M, Royo JL, Rocaspana R, Aparicio E, Pamplona R, Palau A, Sanuy D, Fibla J, Portero-Otin M.

PLoS One. 2017 Jul 27;12(7):e0181697. doi: 10.1371/journal.pone.0181697. eCollection 2017.

28.

Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system.

Naudí A, Cabré R, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):485-495. doi: 10.1016/j.bbalip.2017.02.001. Epub 2017 Feb 7.

PMID:
28185952
29.

A plasma metabolomic signature discloses human breast cancer.

Jové M, Collado R, Quiles JL, Ramírez-Tortosa MC, Sol J, Ruiz-Sanjuan M, Fernandez M, de la Torre Cabrera C, Ramírez-Tortosa C, Granados-Principal S, Sánchez-Rovira P, Pamplona R.

Oncotarget. 2017 Mar 21;8(12):19522-19533. doi: 10.18632/oncotarget.14521.

30.

Specific Metabolomics Adaptations Define a Differential Regional Vulnerability in the Adult Human Cerebral Cortex.

Cabré R, Jové M, Naudí A, Ayala V, Piñol-Ripoll G, Gil-Villar MP, Dominguez-Gonzalez M, Obis È, Berdun R, Mota-Martorell N, Portero-Otin M, Ferrer I, Pamplona R.

Front Mol Neurosci. 2016 Dec 8;9:138. doi: 10.3389/fnmol.2016.00138. eCollection 2016.

31.

Adipocyte lipopolysaccharide binding protein (LBP) is linked to a specific lipidomic signature.

Moreno-Navarrete JM, Jové M, Padró T, Boada J, Ortega F, Ricart W, Pamplona R, Badimón L, Portero-Otín M, Fernández-Real JM.

Obesity (Silver Spring). 2017 Feb;25(2):391-400. doi: 10.1002/oby.21711. Epub 2016 Dec 21.

32.

Sixty years old is the breakpoint of human frontal cortex aging.

Cabré R, Naudí A, Dominguez-Gonzalez M, Ayala V, Jové M, Mota-Martorell N, Piñol-Ripoll G, Gil-Villar MP, Rué M, Portero-Otín M, Ferrer I, Pamplona R.

Free Radic Biol Med. 2017 Feb;103:14-22. doi: 10.1016/j.freeradbiomed.2016.12.010. Epub 2016 Dec 13.

PMID:
27979658
33.

Metabolomics Predicts Neuroimaging Characteristics of Transient Ischemic Attack Patients.

Purroy F, Cambray S, Mauri-Capdevila G, Jové M, Sanahuja J, Farré J, Benabdelhak I, Molina-Seguin J, Colàs-Campàs L, Begue R, Gil MI, Pamplona R, Portero-Otín M.

EBioMedicine. 2016 Dec;14:131-138. doi: 10.1016/j.ebiom.2016.11.010. Epub 2016 Nov 9.

34.

Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autophagy, in the liver of middle-aged mice.

Martínez-Cisuelo V, Gómez J, García-Junceda I, Naudí A, Cabré R, Mota-Martorell N, López-Torres M, González-Sánchez M, Pamplona R, Barja G.

Exp Gerontol. 2016 Oct;83:130-8. doi: 10.1016/j.exger.2016.08.002. Epub 2016 Aug 4.

PMID:
27498120
35.

Metabotyping human endometrioid endometrial adenocarcinoma reveals an implication of endocannabinoid metabolism.

Jové M, Gatius S, Yeramian A, Portero-Otin M, Eritja N, Santacana M, Colas E, Ruiz M, Pamplona R, Matias-Guiu X.

Oncotarget. 2016 Aug 9;7(32):52364-52374. doi: 10.18632/oncotarget.10564.

36.

A Stress-Resistant Lipidomic Signature Confers Extreme Longevity to Humans.

Jové M, Naudí A, Gambini J, Borras C, Cabré R, Portero-Otín M, Viña J, Pamplona R.

J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):30-37. Epub 2016 Mar 24.

PMID:
27013396
37.

Redox proteomic profiling of neuroketal-adducted proteins in human brain: Regional vulnerability at middle age increases in the elderly.

Domínguez M, de Oliveira E, Odena MA, Portero M, Pamplona R, Ferrer I.

Free Radic Biol Med. 2016 Jun;95:1-15. doi: 10.1016/j.freeradbiomed.2016.02.034. Epub 2016 Mar 8.

PMID:
26968793
38.

Erratum: Obesity changes the human gut mycobiome.

Mar Rodríguez M, Pérez D, Javier Chaves F, Esteve E, Marin-Garcia P, Xifra G, Vendrell J, Jové M, Pamplona R, Ricart W, Portero-Otin M, Chacón MR, Fernández Real JM.

Sci Rep. 2016 Feb 24;6:21679. doi: 10.1038/srep21679. No abstract available.

39.

Metabolomics uncovers the role of adipose tissue PDXK in adipogenesis and systemic insulin sensitivity.

Moreno-Navarrete JM, Jove M, Ortega F, Xifra G, Ricart W, Obis È, Pamplona R, Portero-Otin M, Fernández-Real JM.

Diabetologia. 2016 Apr;59(4):822-32. doi: 10.1007/s00125-016-3863-1. Epub 2016 Feb 2.

PMID:
26831303
40.

Oral intake of genetically engineered high-carotenoid corn ameliorates hepatomegaly and hepatic steatosis in PTEN haploinsufficient mice.

Eritja N, Arjó G, Santacana M, Gatius S, Ramírez-Núñez O, Arcal L, Serrano JCE, Pamplona R, Dolcet X, Piñol C, Christou P, Matias-Guiu X, Portero-Otin M.

Biochim Biophys Acta. 2016 Apr;1862(4):526-535. doi: 10.1016/j.bbadis.2016.01.018. Epub 2016 Jan 26.

41.

Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis.

Cacabelos D, Ayala V, Granado-Serrano AB, Jové M, Torres P, Boada J, Cabré R, Ramírez-Núñez O, Gonzalo H, Soler-Cantero A, Serrano JC, Bellmunt MJ, Romero MP, Motilva MJ, Nonaka T, Hasegawa M, Ferrer I, Pamplona R, Portero-Otín M.

Neurobiol Dis. 2016 Apr;88:148-60. doi: 10.1016/j.nbd.2016.01.007. Epub 2016 Jan 12.

PMID:
26805387
42.

Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS.

Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J.

Acta Neuropathol Commun. 2016 Jan 13;4:3. doi: 10.1186/s40478-015-0271-6.

43.

Obesity changes the human gut mycobiome.

Mar Rodríguez M, Pérez D, Javier Chaves F, Esteve E, Marin-Garcia P, Xifra G, Vendrell J, Jové M, Pamplona R, Ricart W, Portero-Otin M, Chacón MR, Fernández Real JM.

Sci Rep. 2015 Oct 12;5:14600. doi: 10.1038/srep14600. Erratum in: Sci Rep. 2016;6:21679.

44.

Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes.

Pushparaj C, Das A, Purroy R, Nàger M, Herreros J, Pamplona R, Cantí C.

Int J Biochem Cell Biol. 2015 Nov;68:166-75. doi: 10.1016/j.biocel.2015.09.010. Epub 2015 Sep 30. Erratum in: Int J Biochem Cell Biol. 2016 Jan;70:173.

PMID:
26429067
45.

Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy.

Ruiz M, Jové M, Schlüter A, Casasnovas C, Villarroya F, Guilera C, Ortega FJ, Naudí A, Pamplona R, Gimeno R, Fourcade S, Portero-Otín M, Pujol A.

Hum Mol Genet. 2015 Dec 15;24(24):6861-76. doi: 10.1093/hmg/ddv375. Epub 2015 Sep 14.

PMID:
26370417
46.

Neuroinflammatory Gene Regulation, Mitochondrial Function, Oxidative Stress, and Brain Lipid Modifications With Disease Progression in Tau P301S Transgenic Mice as a Model of Frontotemporal Lobar Degeneration-Tau.

López-González I, Aso E, Carmona M, Armand-Ugon M, Blanco R, Naudí A, Cabré R, Portero-Otin M, Pamplona R, Ferrer I.

J Neuropathol Exp Neurol. 2015 Oct;74(10):975-99. doi: 10.1097/NEN.0000000000000241.

PMID:
26360374
47.

Lipidomics of human brain aging and Alzheimer's disease pathology.

Naudí A, Cabré R, Jové M, Ayala V, Gonzalo H, Portero-Otín M, Ferrer I, Pamplona R.

Int Rev Neurobiol. 2015;122:133-89. doi: 10.1016/bs.irn.2015.05.008. Epub 2015 Jun 19. Review.

PMID:
26358893
48.

Long lifespans have evolved with long and monounsaturated fatty acids in birds.

Galván I, Naudí A, Erritzøe J, Møller AP, Barja G, Pamplona R.

Evolution. 2015 Oct;69(10):2776-84. doi: 10.1111/evo.12754. Epub 2015 Sep 24.

PMID:
26294378
49.

Target of rapamycin activation predicts lifespan in fruit flies.

Scialò F, Sriram A, Naudí A, Ayala V, Jové M, Pamplona R, Sanz A.

Cell Cycle. 2015;14(18):2949-58. doi: 10.1080/15384101.2015.1071745.

50.

Nutridynamics: mechanism(s) of action of bioactive compounds and their effects.

Serrano JC, Jove M, Gonzalo H, Pamplona R, Portero-Otin M.

Int J Food Sci Nutr. 2015 Jul;66 Suppl 1:S22-30. Review.

PMID:
26241008

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