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Items: 2

1.

Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.

Frischauf I, Litviňuková M, Schober R, Zayats V, Svobodová B, Bonhenry D, Lunz V, Cappello S, Tociu L, Reha D, Stallinger A, Hochreiter A, Pammer T, Butorac C, Muik M, Groschner K, Bogeski I, Ettrich RH, Romanin C, Schindl R.

Sci Signal. 2017 Nov 28;10(507). pii: eaao0358. doi: 10.1126/scisignal.aao0358.

2.

A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription.

Frischauf I, Zayats V, Deix M, Hochreiter A, Jardin I, Muik M, Lackner B, Svobodová B, Pammer T, Litviňuková M, Sridhar AA, Derler I, Bogeski I, Romanin C, Ettrich RH, Schindl R.

Sci Signal. 2015 Dec 22;8(408):ra131. doi: 10.1126/scisignal.aab1901.

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