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Items: 1 to 50 of 209

1.

Enlisting commensal microbes to resist antibiotic-resistant pathogens.

Keith JW, Pamer EG.

J Exp Med. 2018 Oct 11. pii: jem.20180399. doi: 10.1084/jem.20180399. [Epub ahead of print] Review.

PMID:
30309968
2.

Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant.

Taur Y, Coyte K, Schluter J, Robilotti E, Figueroa C, Gjonbalaj M, Littmann ER, Ling L, Miller L, Gyaltshen Y, Fontana E, Morjaria S, Gyurkocza B, Perales MA, Castro-Malaspina H, Tamari R, Ponce D, Koehne G, Barker J, Jakubowski A, Papadopoulos E, Dahi P, Sauter C, Shaffer B, Young JW, Peled J, Meagher RC, Jenq RR, van den Brink MRM, Giralt SA, Pamer EG, Xavier JB.

Sci Transl Med. 2018 Sep 26;10(460). pii: eaap9489. doi: 10.1126/scitranslmed.aap9489.

PMID:
30257956
3.

The effects of amine-modified single-walled carbon nanotubes on the mouse microbiota.

Mulvey JJ, Littmann ER, Ling L, McDevitt MR, Pamer EG, Scheinberg DA.

Int J Nanomedicine. 2018 Sep 10;13:5275-5286. doi: 10.2147/IJN.S168554. eCollection 2018.

4.

A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity.

Shipman WD, Chyou S, Ramanathan A, Izmirly PM, Sharma S, Pannellini T, Dasoveanu DC, Qing X, Magro CM, Granstein RD, Lowes MA, Pamer EG, Kaplan DH, Salmon JE, Mehrara BJ, Young JW, Clancy RM, Blobel CP, Lu TT.

Sci Transl Med. 2018 Aug 15;10(454). pii: eaap9527. doi: 10.1126/scitranslmed.aap9527.

PMID:
30111646
5.

Interbacterial mechanisms of colonization resistance and the strategies pathogens use to overcome them.

Sorbara MT, Pamer EG.

Mucosal Immunol. 2018 Jul 9. doi: 10.1038/s41385-018-0053-0. [Epub ahead of print] Review.

PMID:
29988120
6.

Distinct behavior of myelomonocytic cells and CD8 T cells underlies the hepatic response to Listeria monocytogenes.

Velázquez P, Williams C, Leiner I, Pamer EG, Dustin ML.

Wellcome Open Res. 2018 Apr 24;3:48. doi: 10.12688/wellcomeopenres.12941.1. eCollection 2018.

7.

Impact of gut colonization with butyrate-producing microbiota on respiratory viral infection following allo-HCT.

Haak BW, Littmann ER, Chaubard JL, Pickard AJ, Fontana E, Adhi F, Gyaltshen Y, Ling L, Morjaria SM, Peled JU, van den Brink MR, Geyer AI, Cross JR, Pamer EG, Taur Y.

Blood. 2018 Jun 28;131(26):2978-2986. doi: 10.1182/blood-2018-01-828996. Epub 2018 Apr 19.

PMID:
29674425
8.

Third-party fecal microbiota transplantation following allo-HCT reconstitutes microbiome diversity.

DeFilipp Z, Peled JU, Li S, Mahabamunuge J, Dagher Z, Slingerland AE, Del Rio C, Valles B, Kempner ME, Smith M, Brown J, Dey BR, El-Jawahri A, McAfee SL, Spitzer TR, Ballen KK, Sung AD, Dalton TE, Messina JA, Dettmer K, Liebisch G, Oefner P, Taur Y, Pamer EG, Holler E, Mansour MK, van den Brink MRM, Hohmann E, Jenq RR, Chen YB.

Blood Adv. 2018 Apr 10;2(7):745-753. doi: 10.1182/bloodadvances.2018017731.

9.

Nutritional Support from the Intestinal Microbiota Improves Hematopoietic Reconstitution after Bone Marrow Transplantation in Mice.

Staffas A, Burgos da Silva M, Slingerland AE, Lazrak A, Bare CJ, Holman CD, Docampo MD, Shono Y, Durham B, Pickard AJ, Cross JR, Stein-Thoeringer C, Velardi E, Tsai JJ, Jahn L, Jay H, Lieberman S, Smith OM, Pamer EG, Peled JU, Cohen DE, Jenq RR, van den Brink MRM.

Cell Host Microbe. 2018 Apr 11;23(4):447-457.e4. doi: 10.1016/j.chom.2018.03.002. Epub 2018 Mar 22.

PMID:
29576480
10.

Multifaceted Defense against Listeria monocytogenes in the Gastro-Intestinal Lumen.

Becattini S, Pamer EG.

Pathogens. 2017 Dec 22;7(1). pii: E1. doi: 10.3390/pathogens7010001. Review.

11.

The intestinal microbiota: Antibiotics, colonization resistance, and enteric pathogens.

Kim S, Covington A, Pamer EG.

Immunol Rev. 2017 Sep;279(1):90-105. doi: 10.1111/imr.12563. Review.

12.

Pathogenicity Locus, Core Genome, and Accessory Gene Contributions to Clostridium difficile Virulence.

Lewis BB, Carter RA, Ling L, Leiner I, Taur Y, Kamboj M, Dubberke ER, Xavier J, Pamer EG.

MBio. 2017 Aug 8;8(4). pii: e00885-17. doi: 10.1128/mBio.00885-17.

13.

Microbiota-Based Therapies for Clostridium difficile and Antibiotic-Resistant Enteric Infections.

Lewis BB, Pamer EG.

Annu Rev Microbiol. 2017 Sep 8;71:157-178. doi: 10.1146/annurev-micro-090816-093549. Epub 2017 Jun 15. Review.

PMID:
28617651
14.

Bacterial pathogens: A spoonful of sugar could be the medicine.

Jung HJ, Pamer EG.

Nature. 2017 Jun 22;546(7659):479-480. doi: 10.1038/nature23084. Epub 2017 Jun 14. No abstract available.

15.

Commensal microbes provide first line defense against Listeria monocytogenes infection.

Becattini S, Littmann ER, Carter RA, Kim SG, Morjaria SM, Ling L, Gyaltshen Y, Fontana E, Taur Y, Leiner IM, Pamer EG.

J Exp Med. 2017 Jul 3;214(7):1973-1989. doi: 10.1084/jem.20170495. Epub 2017 Jun 6.

16.

Protective Factors in the Intestinal Microbiome Against Clostridium difficile Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation.

Lee YJ, Arguello ES, Jenq RR, Littmann E, Kim GJ, Miller LC, Ling L, Figueroa C, Robilotti E, Perales MA, Barker JN, Giralt S, van den Brink MRM, Pamer EG, Taur Y.

J Infect Dis. 2017 Apr 1;215(7):1117-1123. doi: 10.1093/infdis/jix011.

17.

Cooperating Commensals Restore Colonization Resistance to Vancomycin-Resistant Enterococcus faecium.

Caballero S, Kim S, Carter RA, Leiner IM, Sušac B, Miller L, Kim GJ, Ling L, Pamer EG.

Cell Host Microbe. 2017 May 10;21(5):592-602.e4. doi: 10.1016/j.chom.2017.04.002.

18.

Microbial Tuning of the Mammalian Immune System.

Pamer EG.

Trends Mol Med. 2017 May;23(5):379-380. doi: 10.1016/j.molmed.2017.03.006. Epub 2017 Mar 31.

19.

Intestinal Microbiota and Relapse After Hematopoietic-Cell Transplantation.

Peled JU, Devlin SM, Staffas A, Lumish M, Khanin R, Littmann ER, Ling L, Kosuri S, Maloy M, Slingerland JB, Ahr KF, Porosnicu Rodriguez KA, Shono Y, Slingerland AE, Docampo MD, Sung AD, Weber D, Alousi AM, Gyurkocza B, Ponce DM, Barker JN, Perales MA, Giralt SA, Taur Y, Pamer EG, Jenq RR, van den Brink MRM.

J Clin Oncol. 2017 May 20;35(15):1650-1659. doi: 10.1200/JCO.2016.70.3348. Epub 2017 Mar 15.

20.

Microbiota Disruption Induced by Early Use of Broad-Spectrum Antibiotics Is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation.

Weber D, Jenq RR, Peled JU, Taur Y, Hiergeist A, Koestler J, Dettmer K, Weber M, Wolff D, Hahn J, Pamer EG, Herr W, Gessner A, Oefner PJ, van den Brink MRM, Holler E.

Biol Blood Marrow Transplant. 2017 May;23(5):845-852. doi: 10.1016/j.bbmt.2017.02.006. Epub 2017 Feb 14.

21.

Short- and long-term effects of oral vancomycin on the human intestinal microbiota.

Isaac S, Scher JU, Djukovic A, Jiménez N, Littman DR, Abramson SB, Pamer EG, Ubeda C.

J Antimicrob Chemother. 2017 Jan;72(1):128-136. Epub 2016 Oct 5.

22.

Clostridium difficile colitis: pathogenesis and host defence.

Abt MC, McKenney PT, Pamer EG.

Nat Rev Microbiol. 2016 Oct;14(10):609-20. doi: 10.1038/nrmicro.2016.108. Epub 2016 Aug 30. Review.

23.

Celecoxib Alters the Intestinal Microbiota and Metabolome in Association with Reducing Polyp Burden.

Montrose DC, Zhou XK, McNally EM, Sue E, Yantiss RK, Gross SS, Leve ND, Karoly ED, Suen CS, Ling L, Benezra R, Pamer EG, Dannenberg AJ.

Cancer Prev Res (Phila). 2016 Sep;9(9):721-31. doi: 10.1158/1940-6207.CAPR-16-0095. Epub 2016 Jul 18.

24.

Bile acid sensitivity and in vivo virulence of clinical Clostridium difficile isolates.

Lewis BB, Carter RA, Pamer EG.

Anaerobe. 2016 Oct;41:32-36. doi: 10.1016/j.anaerobe.2016.05.010. Epub 2016 May 27.

25.

Complete Genome Sequence of Enterococcus faecium ATCC 700221.

McKenney PT, Ling L, Wang G, Mane S, Pamer EG.

Genome Announc. 2016 May 19;4(3). pii: e00386-16. doi: 10.1128/genomeA.00386-16.

26.

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice.

Shono Y, Docampo MD, Peled JU, Perobelli SM, Velardi E, Tsai JJ, Slingerland AE, Smith OM, Young LF, Gupta J, Lieberman SR, Jay HV, Ahr KF, Porosnicu Rodriguez KA, Xu K, Calarfiore M, Poeck H, Caballero S, Devlin SM, Rapaport F, Dudakov JA, Hanash AM, Gyurkocza B, Murphy GF, Gomes C, Liu C, Moss EL, Falconer SB, Bhatt AS, Taur Y, Pamer EG, van den Brink MRM, Jenq RR.

Sci Transl Med. 2016 May 18;8(339):339ra71. doi: 10.1126/scitranslmed.aaf2311.

27.

Antibiotic-Induced Changes in the Intestinal Microbiota and Disease.

Becattini S, Taur Y, Pamer EG.

Trends Mol Med. 2016 Jun;22(6):458-478. doi: 10.1016/j.molmed.2016.04.003. Epub 2016 May 10. Review.

28.

Resurrecting the intestinal microbiota to combat antibiotic-resistant pathogens.

Pamer EG.

Science. 2016 Apr 29;352(6285):535-8. doi: 10.1126/science.aad9382. Review.

29.

Microbiome mediation of infections in the cancer setting.

Taur Y, Pamer EG.

Genome Med. 2016 Apr 18;8(1):40. doi: 10.1186/s13073-016-0306-z. Review.

30.

Influence of Minimum Inhibitory Concentration in Clinical Outcomes of Enterococcus faecium Bacteremia Treated With Daptomycin: Is it Time to Change the Breakpoint?

Shukla BS, Shelburne S, Reyes K, Kamboj M, Lewis JD, Rincon SL, Reyes J, Carvajal LP, Panesso D, Sifri CD, Zervos MJ, Pamer EG, Tran TT, Adachi J, Munita JM, Hasbun R, Arias CA.

Clin Infect Dis. 2016 Jun 15;62(12):1514-1520. doi: 10.1093/cid/ciw173. Epub 2016 Apr 3.

31.

Innate Lymphocyte/Ly6C(hi) Monocyte Crosstalk Promotes Klebsiella Pneumoniae Clearance.

Xiong H, Keith JW, Samilo DW, Carter RA, Leiner IM, Pamer EG.

Cell. 2016 Apr 21;165(3):679-89. doi: 10.1016/j.cell.2016.03.017. Epub 2016 Mar 31.

32.

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells.

Benakis C, Brea D, Caballero S, Faraco G, Moore J, Murphy M, Sita G, Racchumi G, Ling L, Pamer EG, Iadecola C, Anrather J.

Nat Med. 2016 May;22(5):516-23. doi: 10.1038/nm.4068. Epub 2016 Mar 28.

33.

Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation.

Loschko J, Schreiber HA, Rieke GJ, Esterházy D, Meredith MM, Pedicord VA, Yao KH, Caballero S, Pamer EG, Mucida D, Nussenzweig MC.

J Exp Med. 2016 Apr 4;213(4):517-34. doi: 10.1084/jem.20160062. Epub 2016 Mar 21.

34.

TLR-7 activation enhances IL-22-mediated colonization resistance against vancomycin-resistant enterococcus.

Abt MC, Buffie CG, Sušac B, Becattini S, Carter RA, Leiner I, Keith JW, Artis D, Osborne LC, Pamer EG.

Sci Transl Med. 2016 Feb 24;8(327):327ra25. doi: 10.1126/scitranslmed.aad6663.

35.

Role of Clinicogenomics in Infectious Disease Diagnostics and Public Health Microbiology.

Westblade LF, van Belkum A, Grundhoff A, Weinstock GM, Pamer EG, Pallen MJ, Dunne WM Jr.

J Clin Microbiol. 2016 Jul;54(7):1686-1693. doi: 10.1128/JCM.02664-15. Epub 2016 Feb 24.

36.

Control of T cell antigen reactivity via programmed TCR downregulation.

Gallegos AM, Xiong H, Leiner IM, Sušac B, Glickman MS, Pamer EG, van Heijst JW.

Nat Immunol. 2016 Apr;17(4):379-86. doi: 10.1038/ni.3386. Epub 2016 Feb 22.

37.

Gut Microbiota Predict Pulmonary Infiltrates after Allogeneic Hematopoietic Cell Transplantation.

Harris B, Morjaria SM, Littmann ER, Geyer AI, Stover DE, Barker JN, Giralt SA, Taur Y, Pamer EG.

Am J Respir Crit Care Med. 2016 Aug 15;194(4):450-63. doi: 10.1164/rccm.201507-1491OC.

38.

Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis.

Dubin K, Callahan MK, Ren B, Khanin R, Viale A, Ling L, No D, Gobourne A, Littmann E, Huttenhower C, Pamer EG, Wolchok JD.

Nat Commun. 2016 Feb 2;7:10391. doi: 10.1038/ncomms10391.

39.

From Hype to Hope: The Gut Microbiota in Enteric Infectious Disease.

McKenney PT, Pamer EG.

Cell. 2015 Dec 3;163(6):1326-32. doi: 10.1016/j.cell.2015.11.032. Review.

40.

Role of intestinal microbiota in transplantation outcomes.

Taur Y, Jenq RR, Ubeda C, van den Brink M, Pamer EG.

Best Pract Res Clin Haematol. 2015 Jun-Sep;28(2-3):155-61. doi: 10.1016/j.beha.2015.10.013. Epub 2015 Oct 22. Review.

41.

Distinct but Spatially Overlapping Intestinal Niches for Vancomycin-Resistant Enterococcus faecium and Carbapenem-Resistant Klebsiella pneumoniae.

Caballero S, Carter R, Ke X, Sušac B, Leiner IM, Kim GJ, Miller L, Ling L, Manova K, Pamer EG.

PLoS Pathog. 2015 Sep 3;11(9):e1005132. doi: 10.1371/journal.ppat.1005132. eCollection 2015 Sep.

42.

Toxicity Attribution in Phase I Trials: Evaluating the Effect of Dose on the Frequency of Related and Unrelated Toxicities.

Eaton A, Iasonos A, Gounder MM, Pamer EG, Drilon A, Vulih D, Smith GL, Ivy SP, Spriggs DR, Hyman DM.

Clin Cancer Res. 2016 Feb 1;22(3):553-9. doi: 10.1158/1078-0432.CCR-15-0339. Epub 2015 Aug 31.

43.

Innate Immune Defenses Mediated by Two ILC Subsets Are Critical for Protection against Acute Clostridium difficile Infection.

Abt MC, Lewis BB, Caballero S, Xiong H, Carter RA, Sušac B, Ling L, Leiner I, Pamer EG.

Cell Host Microbe. 2015 Jul 8;18(1):27-37. doi: 10.1016/j.chom.2015.06.011.

44.

Distinct Contributions of Neutrophils and CCR2+ Monocytes to Pulmonary Clearance of Different Klebsiella pneumoniae Strains.

Xiong H, Carter RA, Leiner IM, Tang YW, Chen L, Kreiswirth BN, Pamer EG.

Infect Immun. 2015 Sep;83(9):3418-27. doi: 10.1128/IAI.00678-15. Epub 2015 Jun 8.

45.

Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease.

Jenq RR, Taur Y, Devlin SM, Ponce DM, Goldberg JD, Ahr KF, Littmann ER, Ling L, Gobourne AC, Miller LC, Docampo MD, Peled JU, Arpaia N, Cross JR, Peets TK, Lumish MA, Shono Y, Dudakov JA, Poeck H, Hanash AM, Barker JN, Perales MA, Giralt SA, Pamer EG, van den Brink MR.

Biol Blood Marrow Transplant. 2015 Aug;21(8):1373-83. doi: 10.1016/j.bbmt.2015.04.016. Epub 2015 May 11.

46.

Loss of Microbiota-Mediated Colonization Resistance to Clostridium difficile Infection With Oral Vancomycin Compared With Metronidazole.

Lewis BB, Buffie CG, Carter RA, Leiner I, Toussaint NC, Miller LC, Gobourne A, Ling L, Pamer EG.

J Infect Dis. 2015 Nov 15;212(10):1656-65. doi: 10.1093/infdis/jiv256. Epub 2015 Apr 28.

47.

Predictors of early treatment discontinuation in patients enrolled on Phase I oncology trials.

Hyman DM, Eaton AA, Gounder MM, Pamer EG, Pettiford J, Carvajal RD, Ivy SP, Iasonos A, Spriggs DR.

Oncotarget. 2015 Aug 7;6(22):19316-27.

48.

Microbiota-mediated inflammation and antimicrobial defense in the intestine.

Caballero S, Pamer EG.

Annu Rev Immunol. 2015;33:227-56. doi: 10.1146/annurev-immunol-032713-120238. Epub 2015 Jan 2. Review.

49.

Enterococci and Their Interactions with the Intestinal Microbiome.

Dubin K, Pamer EG.

Microbiol Spectr. 2014 Nov;5(6). doi: 10.1128/microbiolspec.BAD-0014-2016.

50.

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

Buffie CG, Bucci V, Stein RR, McKenney PT, Ling L, Gobourne A, No D, Liu H, Kinnebrew M, Viale A, Littmann E, van den Brink MR, Jenq RR, Taur Y, Sander C, Cross JR, Toussaint NC, Xavier JB, Pamer EG.

Nature. 2015 Jan 8;517(7533):205-8. doi: 10.1038/nature13828. Epub 2014 Oct 22.

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