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DAXX mutations as potential genomic markers of malignant evolution in small nonfunctioning pancreatic neuroendocrine tumors.

Cives M, Partelli S, Palmirotta R, Lovero D, Mandriani B, Quaresmini D, Pelle' E, Andreasi V, Castelli P, Strosberg J, Zamboni G, Falconi M, Silvestris F.

Sci Rep. 2019 Dec 9;9(1):18614. doi: 10.1038/s41598-019-55156-0.


Dissection of major cancer gene variants in subsets of circulating tumor cells in advanced breast cancer.

D'Oronzo S, Lovero D, Palmirotta R, Stucci LS, Tucci M, Felici C, Cascardi E, Giardina C, Cafforio P, Silvestris F.

Sci Rep. 2019 Nov 21;9(1):17276. doi: 10.1038/s41598-019-53660-x.


Cutaneous metastasis as a primary presentation of a pulmonary enteric adenocarcinoma.

Todisco A, Internò V, Stucci LS, Ostuni C, Lovero D, D'Oronzo S, Mele F, Duda L, Palmirotta R, Silvestris F.

Int J Biol Markers. 2019 Dec;34(4):421-426. doi: 10.1177/1724600819877190. Epub 2019 Sep 26.


Age-Dependent Levels of Protein Kinase Cs in Brain: Reduction of Endogenous Mechanisms of Neuroprotection.

Pastore D, Pacifici F, Dave KR, Palmirotta R, Bellia A, Pasquantonio G, Guadagni F, Donadel G, Di Daniele N, Abete P, Lauro D, Rundek T, Perez-Pinzon MA, Della-Morte D.

Int J Mol Sci. 2019 Jul 19;20(14). pii: E3544. doi: 10.3390/ijms20143544. Review.


Nutrition and Female Fertility: An Interdependent Correlation.

Silvestris E, Lovero D, Palmirotta R.

Front Endocrinol (Lausanne). 2019 Jun 7;10:346. doi: 10.3389/fendo.2019.00346. eCollection 2019. Review.


Dopamine-beta-hydroxylase 19-bp insertion/deletion polymorphism affects medication overuse in patients with chronic migraine.

Barbanti P, Guadagni F, De Marchis ML, Ialongo C, Egeo G, Fofi L, Aurilia C, Lovero D, Della-Morte D, Ferroni P, Palmirotta R.

Neurol Sci. 2019 Aug;40(8):1717-1724. doi: 10.1007/s10072-019-03865-9. Epub 2019 Apr 10.


Rare Dihydropyrimidine Dehydrogenase Variants and Toxicity by Floropyrimidines: A Case Report.

Palmirotta R, Lovero D, Delacour H, Le Roy A, Cremades S, Silvestris F.

Front Oncol. 2019 Mar 11;9:139. doi: 10.3389/fonc.2019.00139. eCollection 2019.


Animal-type melanoma: dog or wolf? A review of the literature and a case report.

Stucci LS, Palmirotta R, Lovero D, Silvestris E, Cafforio P, Felici C, Todisco A, Nacchiero E, Pezzuto F, Tucci M, Silvestris F.

Expert Rev Mol Med. 2018 Sep 12;20:e5. doi: 10.1017/erm.2018.4. Review.


Liquid biopsy of cancer: a multimodal diagnostic tool in clinical oncology.

Palmirotta R, Lovero D, Cafforio P, Felici C, Mannavola F, Pellè E, Quaresmini D, Tucci M, Silvestris F.

Ther Adv Med Oncol. 2018 Aug 29;10:1758835918794630. doi: 10.1177/1758835918794630. eCollection 2018. Review.


Vitamin D in melanoma: Controversies and potential role in combination with immune check-point inhibitors.

Stucci LS, D'Oronzo S, Tucci M, Macerollo A, Ribero S, Spagnolo F, Marra E, Picasso V, Orgiano L, Marconcini R, De Rosa F, Di Guardo L, Galli G, Gandini S, Palmirotta R, Palmieri G, Queirolo P, Silvestris F; Italian Melanoma Intergroup (IMI).

Cancer Treat Rev. 2018 Sep;69:21-28. doi: 10.1016/j.ctrv.2018.05.016. Epub 2018 May 31. Review.


SNPs in predicting clinical efficacy and toxicity of chemotherapy: walking through the quicksand.

Palmirotta R, Carella C, Silvestris E, Cives M, Stucci SL, Tucci M, Lovero D, Silvestris F.

Oncotarget. 2018 May 18;9(38):25355-25382. doi: 10.18632/oncotarget.25256. eCollection 2018 May 18. Review.


Diabetes Mellitus and Ischemic Heart Disease: The Role of Ion Channels.

Severino P, D'Amato A, Netti L, Pucci M, De Marchis M, Palmirotta R, Volterrani M, Mancone M, Fedele F.

Int J Mol Sci. 2018 Mar 10;19(3). pii: E802. doi: 10.3390/ijms19030802. Review.


Genetic bases of the nutritional approach to migraine.

De Marchis ML, Guadagni F, Silvestris E, Lovero D, Della-Morte D, Ferroni P, Barbanti P, Palmirotta R.

Crit Rev Food Sci Nutr. 2019;59(14):2308-2320. doi: 10.1080/10408398.2018.1450215. Epub 2018 Apr 3. Review.


Double Heterozygosity for BRCA1 Pathogenic Variant and BRCA2 Polymorphic Stop Codon K3326X: A Case Report in a Southern Italian Family.

Palmirotta R, Lovero D, Stucci LS, Silvestris E, Quaresmini D, Cardascia A, Silvestris F.

Int J Mol Sci. 2018 Jan 18;19(1). pii: E285. doi: 10.3390/ijms19010285.


Immune-related adverse events during anticancer immunotherapy: Pathogenesis and management.

Stucci S, Palmirotta R, Passarelli A, Silvestris E, Argentiero A, Lanotte L, Acquafredda S, Todisco A, Silvestris F.

Oncol Lett. 2017 Nov;14(5):5671-5680. doi: 10.3892/ol.2017.6919. Epub 2017 Sep 8.


Redox Mechanisms in Migraine: Novel Therapeutics and Dietary Interventions.

Ferroni P, Barbanti P, Della-Morte D, Palmirotta R, Jirillo E, Guadagni F.

Antioxid Redox Signal. 2018 Apr 20;28(12):1144-1183. doi: 10.1089/ars.2017.7260. Epub 2017 Nov 21. Review.


Procoagulant imbalance in premenopausal women with chronic migraine.

Ferroni P, Barbanti P, Aurilia C, Egeo G, Fofi L, La Farina F, Valente MG, De Marchis ML, Spila A, Palmirotta R, Della-Morte D, Guadagni F.

Neurology. 2017 Oct 3;89(14):1525-1527. doi: 10.1212/WNL.0000000000004435. Epub 2017 Aug 25. No abstract available.


Ovarian cancer: Novel molecular aspects for clinical assessment.

Palmirotta R, Silvestris E, D'Oronzo S, Cardascia A, Silvestris F.

Crit Rev Oncol Hematol. 2017 Sep;117:12-29. doi: 10.1016/j.critrevonc.2017.06.007. Epub 2017 Jun 17. Review.


Desmoid Tumors in Familial Adenomatous Polyposis.

DE Marchis ML, Tonelli F, Quaresmini D, Lovero D, Della-Morte D, Silvestris F, Guadagni F, Palmirotta R.

Anticancer Res. 2017 Jul;37(7):3357-3366. Review.


Next-generation Sequencing (NGS) Analysis on Single Circulating Tumor Cells (CTCs) with No Need of Whole-genome Amplification (WGA).

Palmirotta R, Lovero D, Silvestris E, Felici C, Quaresmini D, Cafforio P, Silvestris F.

Cancer Genomics Proteomics. 2017 May-Jun;14(3):173-179.


Characterization of a rare nonpathogenic sequence variant (c.1905C>T) of the dihydropyrimidine dehydrogenase gene (DPYD).

Palmirotta R, Lovero D, Silvestris E, Carella C, Felici C, Quaresmini D, Cafforio P, Silvestris F.

Int J Biol Markers. 2017 Jul 24;32(3):e357-e360. doi: 10.5301/ijbm.5000260.


Sex-Genetic Interaction in the Risk for Cerebrovascular Disease.

Pastore D, Pacifici F, Capuani B, Palmirotta R, Dong C, Coppola A, Abete P, Roselli M, Sbraccia P, Guadagni F, Lauro D, Rundek T, Della-Morte D.

Curr Med Chem. 2017;24(24):2687-2699. doi: 10.2174/0929867324666170417100318. Review.


O039. Case-control genetic association studies in migraine: a 7-year experience at the Interinstitutional Multidisciplinary Biobank (BioBIM) of IRCCS San Raffaele Pisana.

Barbanti P, Palmirotta R, De Marchis ML, Ialongo C, Egeo G, Aurilia C, Fofi L, Piroso S, Fratangeli F, Valente MG, Guadagni F.

J Headache Pain. 2015 Dec;16(Suppl 1):A120. doi: 10.1186/1129-2377-16-S1-A120. No abstract available.


ALK gene alterations in cancer: biological aspects and therapeutic implications.

Palmirotta R, Quaresmini D, Lovero D, Silvestris F.

Pharmacogenomics. 2017 Feb;18(3):277-292. doi: 10.2217/pgs-2016-0166. Epub 2017 Jan 23.


Serotonin receptor targeted therapy for migraine treatment: an overview of drugs in phase I and II clinical development.

Barbanti P, Aurilia C, Egeo G, Fofi L, Palmirotta R.

Expert Opin Investig Drugs. 2017 Mar;26(3):269-277. doi: 10.1080/13543784.2017.1283404. Epub 2017 Feb 1. Review.


[Genomics of lung adenocarcinoma: pathogenetic significance and clinical applications.]

Palmirotta R, Acquafredda S, Argentiero A, Carella C, Lanotte L, Pappagallo N, Quaresmini D, Silvestris F.

Recenti Prog Med. 2016 Dec;107(12):652-672. doi: 10.1701/2502.26236. Review. Italian.


Characterization of a Rare Nonpathogenic Methylenetetrahydrofolatereductase (MTHFR) Gene Mutation p.Lys215del in a Southern Italian family.

Palmirotta R, Lovero D, Silvestris E, Simone V, Lanotte L, Quaresmini D, Silvestris F.

Hum Mutat. 2017 Jan;38(1):120-121. doi: 10.1002/humu.23132. Epub 2016 Oct 21. No abstract available.


The role of epsilon PKC in acute and chronic diseases: Possible pharmacological implications of its modulators.

Capuani B, Pacifici F, Pastore D, Palmirotta R, Donadel G, Arriga R, Bellia A, Di Daniele N, Rogliani P, Abete P, Sbraccia P, Guadagni F, Lauro D, Della-Morte D.

Pharmacol Res. 2016 Sep;111:659-667. doi: 10.1016/j.phrs.2016.07.029. Epub 2016 Jul 25. Review.


Sirtuins and Cancer: Role in the Epithelial-Mesenchymal Transition.

Palmirotta R, Cives M, Della-Morte D, Capuani B, Lauro D, Guadagni F, Silvestris F.

Oxid Med Cell Longev. 2016;2016:3031459. doi: 10.1155/2016/3031459. Epub 2016 Jun 9. Review.


Parallelism of DOG1 expression with recurrence risk in gastrointestinal stromal tumors bearing KIT or PDGFRA mutations.

Rizzo FM, Palmirotta R, Marzullo A, Resta N, Cives M, Tucci M, Silvestris F.

BMC Cancer. 2016 Feb 11;16:87. doi: 10.1186/s12885-016-2111-x.


Ensuring Sample Quality for Biomarker Discovery Studies - Use of ICT Tools to Trace Biosample Life-cycle.

Riondino S, Ferroni P, Spila A, Alessandroni J, D'Alessandro R, Formica V, Della-Morte D, Palmirotta R, Nanni U, Roselli M, Guadagni F.

Cancer Genomics Proteomics. 2015 Nov-Dec;12(6):291-9. Review.


VEGF gene promoter polymorphisms and risk of VTE in chemotherapy-treated cancer patients.

Ferroni P, Palmirotta R, Riondino S, De Marchis ML, Nardecchia A, Formica V, Guadagni F, Roselli M.

Thromb Haemost. 2016 Jan;115(1):143-51. doi: 10.1160/TH15-03-0259. Epub 2015 Sep 3.


Role of Serum and Glucocorticoid-Inducible Kinase (SGK)-1 in Senescence: A Novel Molecular Target Against Age-Related Diseases.

Lauro D, Pastore D, Capuani B, Pacifici F, Palmirotta R, Abete P, Roselli M, Bellia A, Federici M, Di Daniele N, Sbraccia P, Guadagni F, Lauro R, Della-Morte D.

Curr Med Chem. 2015;22(33):3765-88. Review.


Type 2 Diabetes and Breast Cancer: The Interplay between Impaired Glucose Metabolism and Oxidant Stress.

Ferroni P, Riondino S, Buonomo O, Palmirotta R, Guadagni F, Roselli M.

Oxid Med Cell Longev. 2015;2015:183928. doi: 10.1155/2015/183928. Epub 2015 Jun 11. Review.


Comparison of therapy with Ticagrelor, Prasugrel or high Clopidogrel dose in PCI patients with high on treatment platelet reactivity and genotype variation. TRIPLETE RESET trial.

Sardella G, Calcagno S, Mancone M, Lucisano L, Pennacchi M, Stio RE, Placentino F, Di Roma A, Cavallo E, Palmirotta R, Guadagni F, Fedele F.

Int J Cardiol. 2015 Sep 1;194:60-2. doi: 10.1016/j.ijcard.2015.05.085. Epub 2015 May 15. No abstract available.


Look beyond Catechol-O-Methyltransferase genotype for cathecolamines derangement in migraine: the BioBIM rs4818 and rs4680 polymorphisms study.

De Marchis ML, Barbanti P, Palmirotta R, Egeo G, Aurilia C, Fofi L, Piroso S, Ialongo C, Della-Morte D, D'Andrea G, Ferroni P, Guadagni F.

J Headache Pain. 2015;16:520. doi: 10.1186/s10194-015-0520-x. Epub 2015 Apr 30.


Impact of VEGF gene polymorphisms in elderly cancer patients: clinical outcome and toxicity.

Della-Morte D, Riondino S, Ferroni P, Palmirotta R, Pastore D, Lauro D, Guadagni F, Roselli M.

Pharmacogenomics. 2015 Jan;16(1):61-78. doi: 10.2217/pgs.14.136. Review.


Pharmacogenomics and pharmacogenetics of thiazolidinediones: role in diabetes and cardiovascular risk factors.

Della-Morte D, Palmirotta R, Rehni AK, Pastore D, Capuani B, Pacifici F, De Marchis ML, Dave KR, Bellia A, Fogliame G, Ferroni P, Donadel G, Cacciatore F, Abete P, Dong C, Pileggi A, Roselli M, Ricordi C, Sbraccia P, Guadagni F, Rundek T, Lauro D.

Pharmacogenomics. 2014 Dec;15(16):2063-82. doi: 10.2217/pgs.14.162. Review.


Progesterone receptor gene (PROGINS) polymorphism correlates with late onset of migraine.

Palmirotta R, Barbanti P, Ialongo C, De Marchis ML, Alessandroni J, Egeo G, Aurilia C, Fofi L, Valente MG, Ferroni P, Della-Morte D, Guadagni F.

DNA Cell Biol. 2015 Mar;34(3):208-12. doi: 10.1089/dna.2014.2534. Epub 2014 Dec 10.


Is SOD2 Ala16Val polymorphism associated with migraine with aura phenotype?

Palmirotta R, Barbanti P, De Marchis ML, Egeo G, Aurilia C, Fofi L, Ialongo C, Valente MG, Ferroni P, Della-Morte D, Guadagni F.

Antioxid Redox Signal. 2015 Jan 20;22(3):275-9. doi: 10.1089/ars.2014.6069. Epub 2014 Nov 11.


Diagnostic procedures for paraffin-embedded tissues analysis in pharmacogenomic studies.

Palmirotta R, De Marchis ML, Ludovici G, Ferroni P, Abete P, Guadagni F, Della-Morte D.

Methods Mol Biol. 2014;1175:45-65. doi: 10.1007/978-1-4939-0956-8_4.


Obesity and colorectal cancer: role of adipokines in tumor initiation and progression.

Riondino S, Roselli M, Palmirotta R, Della-Morte D, Ferroni P, Guadagni F.

World J Gastroenterol. 2014 May 14;20(18):5177-90. doi: 10.3748/wjg.v20.i18.5177. Review.


Plasma plasminogen activator inhibitor-1 (PAI-1) levels in breast cancer - relationship with clinical outcome.

Ferroni P, Roselli M, Portarena I, Formica V, Riondino S, LA Farina F, Costarelli L, Melino A, Massimiani G, Cavaliere F, Palmirotta R, Guadagni F.

Anticancer Res. 2014 Mar;34(3):1153-61.


Association between migraine and ACE gene (insertion/deletion) polymorphism: the BioBIM study.

Palmirotta R, Barbanti P, Ludovici G, De Marchis ML, Ialongo C, Egeo G, Aurilia C, Fofi L, Abete P, Spila A, Ferroni P, Della-Morte D, Guadagni F.

Pharmacogenomics. 2014 Feb;15(2):147-55. doi: 10.2217/pgs.13.186.


Age-related reduction of cerebral ischemic preconditioning: myth or reality?

Della-Morte D, Cacciatore F, Salsano E, Pirozzi G, Del Genio MT, D'Antonio I, Gargiulo G, Palmirotta R, Guadagni F, Rundek T, Abete P.

Clin Interv Aging. 2013;8:1055-61. doi: 10.2147/CIA.S47462. Epub 2013 Aug 8. Review.


Role of genetic polymorphisms of ion channels in the pathophysiology of coronary microvascular dysfunction and ischemic heart disease.

Fedele F, Mancone M, Chilian WM, Severino P, Canali E, Logan S, De Marchis ML, Volterrani M, Palmirotta R, Guadagni F.

Basic Res Cardiol. 2013 Nov;108(6):387. doi: 10.1007/s00395-013-0387-4. Epub 2013 Sep 26.


An importance of identification of double variant methylenetetrahydrofolate reductase gene C677T and A1298C in cis configuration for pharmacogenetic studies.

Palmirotta R, Leone B, De Marchis ML, Ludovici G, Savonarola A, Ferroni P, Rundek T, Roselli M, Della-Morte D, Guadagni F.

Blood Coagul Fibrinolysis. 2013 Oct;24(7):784-6. doi: 10.1097/MBC.0b013e3283642d5b. No abstract available.


A reliable and reproducible technique for DNA fingerprinting in biorepositories: a pilot study from BioBIM.

Palmirotta R, De Marchis ML, Ludovici G, Ialongo C, Leone B, Lopez N, Valente MG, Spila A, Ferroni P, Della-Morte D, Guadagni F.

Int J Biol Markers. 2013 Dec 17;28(4):e398-404. doi: 10.5301/JBM.5000044.


TNF-α gene promoter polymorphisms and risk of venous thromboembolism in gastrointestinal cancer patients undergoing chemotherapy.

Roselli M, Ferroni P, Rolfo C, Peeters M, Palmirotta R, Formica V, Ludovici G, Laudisi A, De Marchis ML, La Farina F, Russo A, Guadagni F.

Ann Oncol. 2013 Oct;24(10):2571-5. doi: 10.1093/annonc/mdt251. Epub 2013 Jul 12.


Mutational analysis of gastrointestinal stromal tumors (GISTs): procedural approach for diagnostic purposes.

Palmirotta R, De Marchis ML, Ludovici G, Leone B, Covello R, Conti S, Costarelli L, Della-Morte D, Ferroni P, Roselli M, Guadagni F.

Cancer Genomics Proteomics. 2013 May-Jun;10(3):115-23.


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