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Single nucleotide polymorphism heritability and differential patterns of genetic overlap between inattention and four neurocognitive factors in youth.

Micalizzi L, Brick LA, Marraccini ME, Benca-Bachman CE, Palmer RHC, Knopik VS.

Dev Psychopathol. 2020 Jan 21:1-11. doi: 10.1017/S0954579419001573. [Epub ahead of print]


Repotrectinib (TPX-0005), effectively reduces growth of ALK driven neuroblastoma cells.

Cervantes-Madrid D, Szydzik J, Lind DE, Borenäs M, Bemark M, Cui J, Palmer RH, Hallberg B.

Sci Rep. 2019 Dec 18;9(1):19353. doi: 10.1038/s41598-019-55060-7.


Anisotropic Redox Conductivity within a Metal-Organic Framework Material.

Goswami S, Hod I, Duan JD, Kung CW, Rimoldi M, Malliakas CD, Palmer RH, Farha OK, Hupp JT.

J Am Chem Soc. 2019 Nov 6;141(44):17696-17702. doi: 10.1021/jacs.9b07658. Epub 2019 Oct 23.


Analysis of ALK, MYCN, and the ALK ligand ALKAL2 (FAM150B/AUGα) in neuroblastoma patient samples with chromosome arm 2p rearrangements.

Javanmardi N, Fransson S, Djos A, Umapathy G, Östensson M, Milosevic J, Borenäs M, Hallberg B, Kogner P, Martinsson T, Palmer RH.

Genes Chromosomes Cancer. 2019 Jul 24. doi: 10.1002/gcc.22790. [Epub ahead of print]


Alectinib, an Anaplastic Lymphoma Kinase Inhibitor, Abolishes ALK Activity and Growth in ALK-Positive Neuroblastoma Cells.

Alam MW, Borenäs M, Lind DE, Cervantes-Madrid D, Umapathy G, Palmer RH, Hallberg B.

Front Oncol. 2019 Jul 5;9:579. doi: 10.3389/fonc.2019.00579. eCollection 2019.


Characterization of DSM-IV Opioid Dependence Among Individuals of European Ancestry.

Brick LA, Micalizzi L, Knopik VS, Palmer RHC.

J Stud Alcohol Drugs. 2019 May;80(3):319-330.


The etiology of DSM-5 alcohol use disorder: Evidence of shared and non-shared additive genetic effects.

Palmer RHC, Brick LA, Chou YL, Agrawal A, McGeary JE, Heath AC, Bierut L, Keller MC, Johnson E, Hartz SM, Schuckit MA, Knopik VS.

Drug Alcohol Depend. 2019 Aug 1;201:147-154. doi: 10.1016/j.drugalcdep.2018.12.034. Epub 2019 Jun 14.


CNR1 and FAAH variation and affective states induced by marijuana smoking.

Palmer RHC, McGeary JE, Knopik VS, Bidwell LC, Metrik JM.

Am J Drug Alcohol Abuse. 2019;45(5):514-526. doi: 10.1080/00952990.2019.1614596. Epub 2019 Jun 11.


An assessment of mechanical properties and screw push-out for two 3.5-mm pearl-type locking plate systems.

Tremolada G, Taggart R, Lewis DD, Palmer RH, Lambrechts NE.

Am J Vet Res. 2019 Jun;80(6):533-538. doi: 10.2460/ajvr.80.6.533.


Efficacy and safety of memantine in children with autism spectrum disorder: Results from three phase 2 multicenter studies.

Hardan AY, Hendren RL, Aman MG, Robb A, Melmed RD, Andersen KA, Luchini R, Rahman R, Ali S, Jia XD, Mallick M, Lateiner JE, Palmer RH, Graham SM.

Autism. 2019 Nov;23(8):2096-2111. doi: 10.1177/1362361318824103. Epub 2019 Apr 26.


13PPhosphoproteome and gene expression profiling of ALK inhibition in neuroblastoma cell lines reveals conserved oncogenic pathways.

Umapathy G, Van den Eynden J, Cervantes-Madrid D, Szydzik J, Guan J, Palmer RH, Hallberg B.

Ann Oncol. 2019 Feb 1;30(Suppl 1). pii: mdz029.006. doi: 10.1093/annonc/mdz029.006. No abstract available.


Targeting anaplastic lymphoma kinase in neuroblastoma.

Umapathy G, Mendoza-Garcia P, Hallberg B, Palmer RH.

APMIS. 2019 May;127(5):288-302. doi: 10.1111/apm.12940. Epub 2019 Apr 3. Review.


Health and criminal justice system involvement among African American siblings.

Beckley AL, Palmer RH, Rocque M, Whitfield KE.

SSM Popul Health. 2019 Jan 25;7:100359. doi: 10.1016/j.ssmph.2019.100359. eCollection 2019 Apr.


Overlapping genetic effects between suicidal ideation and neurocognitive functioning.

Brick LA, Marraccini ME, Micalizzi L, Benca-Bachman CE, Knopik VS, Palmer RHC.

J Affect Disord. 2019 Apr 15;249:104-111. doi: 10.1016/j.jad.2019.02.003. Epub 2019 Feb 6.


Gait and electromyographic alterations due to early onset of injury and eventual rupture of the cranial cruciate ligament in dogs: A pilot study.

Adrian CP, Haussler KK, Kawcak CE, Reiser RF 2nd, Riegger-Krugh C, Palmer RH, McIlwraith CW, Taylor RA.

Vet Surg. 2019 Apr;48(3):388-400. doi: 10.1111/vsu.13178. Epub 2019 Feb 13.


Predictors of the Placebo Response in Irritable Bowel Syndrome With Constipation.

Palmer RH.

Clin Gastroenterol Hepatol. 2019 May;17(6):1215-1216. doi: 10.1016/j.cgh.2018.12.020. Epub 2018 Dec 21. No abstract available.


Characterization of Drosophila Nidogen/entactin reveals roles in basement membrane stability, barrier function and nervous system patterning.

Wolfstetter G, Dahlitz I, Pfeifer K, Töpfer U, Alt JA, Pfeifer DC, Lakes-Harlan R, Baumgartner S, Palmer RH, Holz A.

Development. 2019 Jan 16;146(2). pii: dev168948. doi: 10.1242/dev.168948.


Phosphoproteome and gene expression profiling of ALK inhibition in neuroblastoma cell lines reveals conserved oncogenic pathways.

Van den Eynden J, Umapathy G, Ashouri A, Cervantes-Madrid D, Szydzik J, Ruuth K, Koster J, Larsson E, Guan J, Palmer RH, Hallberg B.

Sci Signal. 2018 Nov 20;11(557). pii: eaar5680. doi: 10.1126/scisignal.aar5680.


Nickel-Carbon-Zirconium Material Derived from Nickel-Oxide Clusters Installed in a Metal-Organic Framework Scaffold by Atomic Layer Deposition.

Palmer RH, Kung CW, Liu J, Farha OK, Hupp JT.

Langmuir. 2018 Nov 27;34(47):14143-14150. doi: 10.1021/acs.langmuir.8b02166. Epub 2018 Nov 13.


Postamputation Orthopedic Surgery in Canine Amputees: Owner Satisfaction and Outcome.

Contreras ET, Worley DR, Palmer RH, Duerr FM.

Top Companion Anim Med. 2018 Sep;33(3):89-96. doi: 10.1053/j.tcam.2018.07.001. Epub 2018 Jul 19.


Bile Acid Deficiency and Constipation.

Palmer RH.

Clin Gastroenterol Hepatol. 2018 Aug;16(8):1363-1364. doi: 10.1016/j.cgh.2018.04.018. No abstract available.


Drosophila model of myosin myopathy rescued by overexpression of a TRIM-protein family member.

Dahl-Halvarsson M, Olive M, Pokrzywa M, Ejeskär K, Palmer RH, Uv AE, Tajsharghi H.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6566-E6575. doi: 10.1073/pnas.1800727115. Epub 2018 Jun 26.


Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib.

Guan J, Fransson S, Siaw JT, Treis D, Van den Eynden J, Chand D, Umapathy G, Ruuth K, Svenberg P, Wessman S, Shamikh A, Jacobsson H, Gordon L, Stenman J, Svensson PJ, Hansson M, Larsson E, Martinsson T, Palmer RH, Kogner P, Hallberg B.

Cold Spring Harb Mol Case Stud. 2018 Aug 1;4(4). pii: a002550. doi: 10.1101/mcs.a002550. Print 2018 Aug.


Electroactive Ferrocene at or near the Surface of Metal-Organic Framework UiO-66.

Palmer RH, Liu J, Kung CW, Hod I, Farha OK, Hupp JT.

Langmuir. 2018 Apr 24;34(16):4707-4714. doi: 10.1021/acs.langmuir.7b03846. Epub 2018 Apr 13.


ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells.

Fadeev A, Mendoza-Garcia P, Irion U, Guan J, Pfeifer K, Wiessner S, Serluca F, Singh AP, Nüsslein-Volhard C, Palmer RH.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E630-E638. doi: 10.1073/pnas.1719137115. Epub 2018 Jan 9.


MEK inhibitor trametinib does not prevent the growth of anaplastic lymphoma kinase (ALK)-addicted neuroblastomas.

Umapathy G, Guan J, Gustafsson DE, Javanmardi N, Cervantes-Madrid D, Djos A, Martinsson T, Palmer RH, Hallberg B.

Sci Signal. 2017 Nov 28;10(507). pii: eaam7550. doi: 10.1126/scisignal.aam7550.


Shared additive genetic variation for alcohol dependence among subjects of African and European ancestry.

Brick LA, Keller MC, Knopik VS, McGeary JE, Palmer RHC.

Addict Biol. 2019 Jan;24(1):132-144. doi: 10.1111/adb.12578. Epub 2017 Nov 27.


HPA axis multilocus genetic profile score moderates the impact of interpersonal stress on prospective increases in depressive symptoms for offspring of depressed mothers.

Feurer C, McGeary JE, Knopik VS, Brick LA, Palmer RH, Gibb BE.

J Abnorm Psychol. 2017 Nov;126(8):1017-1028. doi: 10.1037/abn0000316.


Novel Mechanisms of ALK Activation Revealed by Analysis of the Y1278S Neuroblastoma Mutation.

Guan J, Yamazaki Y, Chand D, van Dijk JR, Ruuth K, Palmer RH, Hallberg B.

Cancers (Basel). 2017 Oct 30;9(11). pii: E149. doi: 10.3390/cancers9110149.


The scaffolding protein Cnk binds to the receptor tyrosine kinase Alk to promote visceral founder cell specification in Drosophila.

Wolfstetter G, Pfeifer K, van Dijk JR, Hugosson F, Lu X, Palmer RH.

Sci Signal. 2017 Oct 24;10(502). pii: eaan0804. doi: 10.1126/scisignal.aan0804.


Inhibitory control in siblings discordant for exposure to maternal smoking during pregnancy.

Micalizzi L, Marceau K, Brick LA, Palmer RH, Todorov AA, Heath AC, Evans A, Knopik VS.

Dev Psychol. 2018 Feb;54(2):199-208. doi: 10.1037/dev0000423. Epub 2017 Oct 23.


Prenatal Exposure Effects on Early Adolescent Substance Use: Preliminary Evidence From a Genetically Informed Bayesian Approach.

Bidwell LC, Marceau K, Brick LA, Karoly HC, Todorov AA, Palmer RH, Heath AC, Knopik VS.

J Stud Alcohol Drugs. 2017 Sep;78(5):789-794.


An investigation of shock wave therapy and low-intensity pulsed ultrasound on fracture healing under reduced loading conditions in an ovine model.

Gadomski BC, McGilvray KC, Easley JT, Palmer RH, Jiao J, Li X, Qin YX, Puttlitz CM.

J Orthop Res. 2018 Mar;36(3):921-929. doi: 10.1002/jor.23666. Epub 2017 Aug 11.


Within-Family Effects of Smoking during Pregnancy on ADHD: the Importance of Phenotype.

Marceau K, Cinnamon Bidwell L, Karoly HC, Evans AS, Todorov AA, Palmer RH, Heath AC, Knopik VS.

J Abnorm Child Psychol. 2018 May;46(4):685-699. doi: 10.1007/s10802-017-0320-7.


The Zic family homologue Odd-paired regulates Alk expression in Drosophila.

Mendoza-García P, Hugosson F, Fallah M, Higgins ML, Iwasaki Y, Pfeifer K, Wolfstetter G, Varshney G, Popichenko D, Gergen JP, Hens K, Deplancke B, Palmer RH.

PLoS Genet. 2017 Apr 3;13(4):e1006617. doi: 10.1371/journal.pgen.1006617. eCollection 2017 Apr.


A Preliminary Study of Genetic Variation in the Dopaminergic and Serotonergic Systems and Genome-wide Additive Genetic Effects on Depression Severity and Treatment Response.

Palmer RH, Beevers CG, McGeary JE, Brick LA, Knopik VS.

Clin Psychol Sci. 2017 Jan;5(1):158-165. doi: 10.1177/2167702616651075. Epub 2016 Oct 19. No abstract available.


The effect of polydioxanone hemicerclage suture on the occurrence of fracture during tibial tuberosity advancement with an elongated bi-directional hinged osteotomy.

Bleakley S, Palmer RH, Bresina S, Roca SP, Tepic S.

Vet Surg. 2017 May;46(4):486-493. doi: 10.1111/vsu.12642. Epub 2017 Mar 17.


Anaplastic lymphoma kinase L1198F and G1201E mutations identified in anaplastic thyroid cancer patients are not ligand-independent.

Guan J, Wolfstetter G, Siaw J, Chand D, Hugosson F, Palmer RH, Hallberg B.

Oncotarget. 2017 Feb 14;8(7):11566-11578. doi: 10.18632/oncotarget.14141.


Use of Proton Pump Inhibitors and Risks of Fundic Gland Polyps and Gastric Cancer: Systematic Review and Meta-analysis.

Palmer RH.

Clin Gastroenterol Hepatol. 2017 May;15(5):790. doi: 10.1016/j.cgh.2016.12.007. Epub 2016 Dec 21. No abstract available.


The role of the ALK receptor in cancer biology.

Hallberg B, Palmer RH.

Ann Oncol. 2016 Sep;27 Suppl 3:iii4-iii15. doi: 10.1093/annonc/mdw301. Review.


The ALK inhibitor PF-06463922 is effective as a single agent in neuroblastoma driven by expression of ALK and MYCN.

Guan J, Tucker ER, Wan H, Chand D, Danielson LS, Ruuth K, El Wakil A, Witek B, Jamin Y, Umapathy G, Robinson SP, Johnson TW, Smeal T, Martinsson T, Chesler L, Palmer RH, Hallberg B.

Dis Model Mech. 2016 Sep 1;9(9):941-52. doi: 10.1242/dmm.024448. Epub 2016 Jul 7.


Comparison of owner satisfaction between stifle joint orthoses and tibial plateau leveling osteotomy for the management of cranial cruciate ligament disease in dogs.

Hart JL, May KD, Kieves NR, Mich PM, Goh CS, Palmer RH, Duerr FM.

J Am Vet Med Assoc. 2016 Aug 15;249(4):391-8. doi: 10.2460/javma.249.4.391.


Hemiepiphysiodesis for the correction of proximal tibial valgus in growing dogs.

Olsen AM, Vezzoni L, Ferretti A, Palmer RH, Vezzoni A, Duerr F.

Vet Comp Orthop Traumatol. 2016 Jul 19;29(4):330-7. doi: 10.3415/VCOT-15-12-0204. Epub 2016 Jun 1.


Evidence of Shared Genome-Wide Additive Genetic Effects on Interpersonal Trauma Exposure and Generalized Vulnerability to Drug Dependence in a Population of Substance Users.

Palmer RH, Nugent NR, Brick LA, Bidwell CL, McGeary JE, Keller MC, Knopik VS.

J Trauma Stress. 2016 Jun;29(3):197-204. doi: 10.1002/jts.22103. Epub 2016 May 23.


Biliary Cirrhosis Treated With Ursodeoxycholic Acid.

Palmer RH.

Gastroenterology. 2016 Jun;150(7):1689. doi: 10.1053/j.gastro.2016.02.083. Epub 2016 Apr 29. No abstract available.


Additive genetic contribution to symptom dimensions in major depressive disorder.

Pearson R, Palmer RH, Brick LA, McGeary JE, Knopik VS, Beevers CG.

J Abnorm Psychol. 2016 May;125(4):495-501. doi: 10.1037/abn0000161.


A Propensity Scoring Approach to Characterizing the Effects of Maternal Smoking During Pregnancy on Offspring's Initial Responses to Cigarettes and Alcohol.

Bidwell LC, Palmer RH, Brick L, Madden PA, Heath AC, Knopik VS.

Behav Genet. 2016 May;46(3):416-30. doi: 10.1007/s10519-016-9791-5. Epub 2016 Apr 20.


Cross-species evidence for the role of interleukin-33 in depression risk.

Kudinova AY, Deak T, Hueston CM, McGeary JE, Knopik VS, Palmer RH, Gibb BE.

J Abnorm Psychol. 2016 May;125(4):482-94. doi: 10.1037/abn0000158. Epub 2016 Apr 7.


Genome-wide single nucleotide polymorphism heritability of nicotine dependence as a multidimensional phenotype.

Bidwell LC, Palmer RH, Brick L, McGeary JE, Knopik VS.

Psychol Med. 2016 Jul;46(10):2059-69. doi: 10.1017/S0033291716000453. Epub 2016 Apr 7.


Brigatinib, an anaplastic lymphoma kinase inhibitor, abrogates activity and growth in ALK-positive neuroblastoma cells, Drosophila and mice.

Siaw JT, Wan H, Pfeifer K, Rivera VM, Guan J, Palmer RH, Hallberg B.

Oncotarget. 2016 May 17;7(20):29011-22. doi: 10.18632/oncotarget.8508.

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