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Overlapping genetic effects between suicidal ideation and neurocognitive functioning.

Brick LA, Marraccini ME, Micalizzi L, Benca-Bachman CE, Knopik VS, Palmer RHC.

J Affect Disord. 2019 Feb 6;249:104-111. doi: 10.1016/j.jad.2019.02.003. [Epub ahead of print]


Gait and electromyographic alterations due to early onset of injury and eventual rupture of the cranial cruciate ligament in dogs: A pilot study.

Adrian CP, Haussler KK, Kawcak CE, Reiser RF 2nd, Riegger-Krugh C, Palmer RH, McIlwraith CW, Taylor RA.

Vet Surg. 2019 Feb 13. doi: 10.1111/vsu.13178. [Epub ahead of print]


Predictors of the Placebo Response in Irritable Bowel Syndrome With Constipation.

Palmer RH.

Clin Gastroenterol Hepatol. 2018 Dec 21. pii: S1542-3565(18)31396-X. doi: 10.1016/j.cgh.2018.12.020. [Epub ahead of print] No abstract available.


Characterization of Drosophila Nidogen/entactin reveals roles in basement membrane stability, barrier function and nervous system patterning.

Wolfstetter G, Dahlitz I, Pfeifer K, Töpfer U, Alt JA, Pfeifer DC, Lakes-Harlan R, Baumgartner S, Palmer RH, Holz A.

Development. 2019 Jan 16;146(2). pii: dev168948. doi: 10.1242/dev.168948.


Phosphoproteome and gene expression profiling of ALK inhibition in neuroblastoma cell lines reveals conserved oncogenic pathways.

Van den Eynden J, Umapathy G, Ashouri A, Cervantes-Madrid D, Szydzik J, Ruuth K, Koster J, Larsson E, Guan J, Palmer RH, Hallberg B.

Sci Signal. 2018 Nov 20;11(557). pii: eaar5680. doi: 10.1126/scisignal.aar5680.


Nickel-Carbon-Zirconium Material Derived from Nickel-Oxide Clusters Installed in a Metal-Organic Framework Scaffold by Atomic Layer Deposition.

Palmer RH, Kung CW, Liu J, Farha OK, Hupp JT.

Langmuir. 2018 Nov 27;34(47):14143-14150. doi: 10.1021/acs.langmuir.8b02166. Epub 2018 Nov 13.


Postamputation Orthopedic Surgery in Canine Amputees: Owner Satisfaction and Outcome.

Contreras ET, Worley DR, Palmer RH, Duerr FM.

Top Companion Anim Med. 2018 Sep;33(3):89-96. doi: 10.1053/j.tcam.2018.07.001. Epub 2018 Jul 19.


Bile Acid Deficiency and Constipation.

Palmer RH.

Clin Gastroenterol Hepatol. 2018 Aug;16(8):1363-1364. doi: 10.1016/j.cgh.2018.04.018. No abstract available.


Drosophila model of myosin myopathy rescued by overexpression of a TRIM-protein family member.

Dahl-Halvarsson M, Olive M, Pokrzywa M, Ejeskär K, Palmer RH, Uv AE, Tajsharghi H.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6566-E6575. doi: 10.1073/pnas.1800727115. Epub 2018 Jun 26.


Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib.

Guan J, Fransson S, Siaw JT, Treis D, Van den Eynden J, Chand D, Umapathy G, Ruuth K, Svenberg P, Wessman S, Shamikh A, Jacobsson H, Gordon L, Stenman J, Svensson PJ, Hansson M, Larsson E, Martinsson T, Palmer RH, Kogner P, Hallberg B.

Cold Spring Harb Mol Case Stud. 2018 Aug 1;4(4). pii: a002550. doi: 10.1101/mcs.a002550. Print 2018 Aug.


Electroactive Ferrocene at or near the Surface of Metal-Organic Framework UiO-66.

Palmer RH, Liu J, Kung CW, Hod I, Farha OK, Hupp JT.

Langmuir. 2018 Apr 24;34(16):4707-4714. doi: 10.1021/acs.langmuir.7b03846. Epub 2018 Apr 13.


ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells.

Fadeev A, Mendoza-Garcia P, Irion U, Guan J, Pfeifer K, Wiessner S, Serluca F, Singh AP, Nüsslein-Volhard C, Palmer RH.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E630-E638. doi: 10.1073/pnas.1719137115. Epub 2018 Jan 9.


MEK inhibitor trametinib does not prevent the growth of anaplastic lymphoma kinase (ALK)-addicted neuroblastomas.

Umapathy G, Guan J, Gustafsson DE, Javanmardi N, Cervantes-Madrid D, Djos A, Martinsson T, Palmer RH, Hallberg B.

Sci Signal. 2017 Nov 28;10(507). pii: eaam7550. doi: 10.1126/scisignal.aam7550.


Shared additive genetic variation for alcohol dependence among subjects of African and European ancestry.

Brick LA, Keller MC, Knopik VS, McGeary JE, Palmer RHC.

Addict Biol. 2019 Jan;24(1):132-144. doi: 10.1111/adb.12578. Epub 2017 Nov 27.


HPA axis multilocus genetic profile score moderates the impact of interpersonal stress on prospective increases in depressive symptoms for offspring of depressed mothers.

Feurer C, McGeary JE, Knopik VS, Brick LA, Palmer RH, Gibb BE.

J Abnorm Psychol. 2017 Nov;126(8):1017-1028. doi: 10.1037/abn0000316.


Novel Mechanisms of ALK Activation Revealed by Analysis of the Y1278S Neuroblastoma Mutation.

Guan J, Yamazaki Y, Chand D, van Dijk JR, Ruuth K, Palmer RH, Hallberg B.

Cancers (Basel). 2017 Oct 30;9(11). pii: E149. doi: 10.3390/cancers9110149.


The scaffolding protein Cnk binds to the receptor tyrosine kinase Alk to promote visceral founder cell specification in Drosophila.

Wolfstetter G, Pfeifer K, van Dijk JR, Hugosson F, Lu X, Palmer RH.

Sci Signal. 2017 Oct 24;10(502). pii: eaan0804. doi: 10.1126/scisignal.aan0804.


Inhibitory control in siblings discordant for exposure to maternal smoking during pregnancy.

Micalizzi L, Marceau K, Brick LA, Palmer RH, Todorov AA, Heath AC, Evans A, Knopik VS.

Dev Psychol. 2018 Feb;54(2):199-208. doi: 10.1037/dev0000423. Epub 2017 Oct 23.


Prenatal Exposure Effects on Early Adolescent Substance Use: Preliminary Evidence From a Genetically Informed Bayesian Approach.

Bidwell LC, Marceau K, Brick LA, Karoly HC, Todorov AA, Palmer RH, Heath AC, Knopik VS.

J Stud Alcohol Drugs. 2017 Sep;78(5):789-794.


An investigation of shock wave therapy and low-intensity pulsed ultrasound on fracture healing under reduced loading conditions in an ovine model.

Gadomski BC, McGilvray KC, Easley JT, Palmer RH, Jiao J, Li X, Qin YX, Puttlitz CM.

J Orthop Res. 2018 Mar;36(3):921-929. doi: 10.1002/jor.23666. Epub 2017 Aug 11.


Within-Family Effects of Smoking during Pregnancy on ADHD: the Importance of Phenotype.

Marceau K, Cinnamon Bidwell L, Karoly HC, Evans AS, Todorov AA, Palmer RH, Heath AC, Knopik VS.

J Abnorm Child Psychol. 2018 May;46(4):685-699. doi: 10.1007/s10802-017-0320-7.


The Zic family homologue Odd-paired regulates Alk expression in Drosophila.

Mendoza-García P, Hugosson F, Fallah M, Higgins ML, Iwasaki Y, Pfeifer K, Wolfstetter G, Varshney G, Popichenko D, Gergen JP, Hens K, Deplancke B, Palmer RH.

PLoS Genet. 2017 Apr 3;13(4):e1006617. doi: 10.1371/journal.pgen.1006617. eCollection 2017 Apr.


A Preliminary Study of Genetic Variation in the Dopaminergic and Serotonergic Systems and Genome-wide Additive Genetic Effects on Depression Severity and Treatment Response.

Palmer RH, Beevers CG, McGeary JE, Brick LA, Knopik VS.

Clin Psychol Sci. 2017 Jan;5(1):158-165. doi: 10.1177/2167702616651075. Epub 2016 Oct 19. No abstract available.


The effect of polydioxanone hemicerclage suture on the occurrence of fracture during tibial tuberosity advancement with an elongated bi-directional hinged osteotomy.

Bleakley S, Palmer RH, Bresina S, Roca SP, Tepic S.

Vet Surg. 2017 May;46(4):486-493. doi: 10.1111/vsu.12642. Epub 2017 Mar 17.


Anaplastic lymphoma kinase L1198F and G1201E mutations identified in anaplastic thyroid cancer patients are not ligand-independent.

Guan J, Wolfstetter G, Siaw J, Chand D, Hugosson F, Palmer RH, Hallberg B.

Oncotarget. 2017 Feb 14;8(7):11566-11578. doi: 10.18632/oncotarget.14141.


Use of Proton Pump Inhibitors and Risks of Fundic Gland Polyps and Gastric Cancer: Systematic Review and Meta-analysis.

Palmer RH.

Clin Gastroenterol Hepatol. 2017 May;15(5):790. doi: 10.1016/j.cgh.2016.12.007. Epub 2016 Dec 21. No abstract available.


The role of the ALK receptor in cancer biology.

Hallberg B, Palmer RH.

Ann Oncol. 2016 Sep;27 Suppl 3:iii4-iii15. doi: 10.1093/annonc/mdw301. Review.


The ALK inhibitor PF-06463922 is effective as a single agent in neuroblastoma driven by expression of ALK and MYCN.

Guan J, Tucker ER, Wan H, Chand D, Danielson LS, Ruuth K, El Wakil A, Witek B, Jamin Y, Umapathy G, Robinson SP, Johnson TW, Smeal T, Martinsson T, Chesler L, Palmer RH, Hallberg B.

Dis Model Mech. 2016 Sep 1;9(9):941-52. doi: 10.1242/dmm.024448. Epub 2016 Jul 7.


Comparison of owner satisfaction between stifle joint orthoses and tibial plateau leveling osteotomy for the management of cranial cruciate ligament disease in dogs.

Hart JL, May KD, Kieves NR, Mich PM, Goh CS, Palmer RH, Duerr FM.

J Am Vet Med Assoc. 2016 Aug 15;249(4):391-8. doi: 10.2460/javma.249.4.391.


Hemiepiphysiodesis for the correction of proximal tibial valgus in growing dogs.

Olsen AM, Vezzoni L, Ferretti A, Palmer RH, Vezzoni A, Duerr F.

Vet Comp Orthop Traumatol. 2016 Jul 19;29(4):330-7. doi: 10.3415/VCOT-15-12-0204. Epub 2016 Jun 1.


Evidence of Shared Genome-Wide Additive Genetic Effects on Interpersonal Trauma Exposure and Generalized Vulnerability to Drug Dependence in a Population of Substance Users.

Palmer RH, Nugent NR, Brick LA, Bidwell CL, McGeary JE, Keller MC, Knopik VS.

J Trauma Stress. 2016 Jun;29(3):197-204. doi: 10.1002/jts.22103. Epub 2016 May 23.


Biliary Cirrhosis Treated With Ursodeoxycholic Acid.

Palmer RH.

Gastroenterology. 2016 Jun;150(7):1689. doi: 10.1053/j.gastro.2016.02.083. Epub 2016 Apr 29. No abstract available.


Additive genetic contribution to symptom dimensions in major depressive disorder.

Pearson R, Palmer RH, Brick LA, McGeary JE, Knopik VS, Beevers CG.

J Abnorm Psychol. 2016 May;125(4):495-501. doi: 10.1037/abn0000161.


A Propensity Scoring Approach to Characterizing the Effects of Maternal Smoking During Pregnancy on Offspring's Initial Responses to Cigarettes and Alcohol.

Bidwell LC, Palmer RH, Brick L, Madden PA, Heath AC, Knopik VS.

Behav Genet. 2016 May;46(3):416-30. doi: 10.1007/s10519-016-9791-5. Epub 2016 Apr 20.


Cross-species evidence for the role of interleukin-33 in depression risk.

Kudinova AY, Deak T, Hueston CM, McGeary JE, Knopik VS, Palmer RH, Gibb BE.

J Abnorm Psychol. 2016 May;125(4):482-94. doi: 10.1037/abn0000158. Epub 2016 Apr 7.


Genome-wide single nucleotide polymorphism heritability of nicotine dependence as a multidimensional phenotype.

Bidwell LC, Palmer RH, Brick L, McGeary JE, Knopik VS.

Psychol Med. 2016 Jul;46(10):2059-69. doi: 10.1017/S0033291716000453. Epub 2016 Apr 7.


Brigatinib, an anaplastic lymphoma kinase inhibitor, abrogates activity and growth in ALK-positive neuroblastoma cells, Drosophila and mice.

Siaw JT, Wan H, Pfeifer K, Rivera VM, Guan J, Palmer RH, Hallberg B.

Oncotarget. 2016 May 17;7(20):29011-22. doi: 10.18632/oncotarget.8508.


Safety and Efficacy of Memantine in Children with Autism: Randomized, Placebo-Controlled Study and Open-Label Extension.

Aman MG, Findling RL, Hardan AY, Hendren RL, Melmed RD, Kehinde-Nelson O, Hsu HA, Trugman JM, Palmer RH, Graham SM, Gage AT, Perhach JL, Katz E.

J Child Adolesc Psychopharmacol. 2017 Jun;27(5):403-412. doi: 10.1089/cap.2015.0146. Epub 2016 Mar 15.


Godzilla-dependent transcytosis promotes Wingless signalling in Drosophila wing imaginal discs.

Yamazaki Y, Palmer L, Alexandre C, Kakugawa S, Beckett K, Gaugue I, Palmer RH, Vincent JP.

Nat Cell Biol. 2016 Apr;18(4):451-7. doi: 10.1038/ncb3325. Epub 2016 Mar 14.


Effects of Maternal Smoking during Pregnancy on Offspring Externalizing Problems: Contextual Effects in a Sample of Female Twins.

Palmer RH, Bidwell LC, Heath AC, Brick LA, Madden PA, Knopik VS.

Behav Genet. 2016 May;46(3):403-15. doi: 10.1007/s10519-016-9779-1. Epub 2016 Jan 29.


Passive rGE or Developmental Gene-Environment Cascade? An Investigation of the Role of Xenobiotic Metabolism Genes in the Association Between Smoke Exposure During Pregnancy and Child Birth Weight.

Marceau K, Palmer RH, Neiderhiser JM, Smith TF, McGeary JE, Knopik VS.

Behav Genet. 2016 May;46(3):365-77. doi: 10.1007/s10519-016-9778-2. Epub 2016 Jan 23.


Smoking during pregnancy and ADHD risk: A genetically informed, multiple-rater approach.

Knopik VS, Marceau K, Bidwell LC, Palmer RH, Smith TF, Todorov A, Evans AS, Heath AC.

Am J Med Genet B Neuropsychiatr Genet. 2016 Oct;171(7):971-81. doi: 10.1002/ajmg.b.32421. Epub 2016 Jan 22.


Computational characterization of fracture healing under reduced gravity loading conditions.

Gadomski BC, Lerner ZF, Browning RC, Easley JT, Palmer RH, Puttlitz CM.

J Orthop Res. 2016 Jul;34(7):1206-15. doi: 10.1002/jor.23143. Epub 2016 Jan 8.


Maternal Smoking During Pregnancy and Offspring Birth Weight: A Genetically-Informed Approach Comparing Multiple Raters.

Knopik VS, Marceau K, Palmer RH, Smith TF, Heath AC.

Behav Genet. 2016 May;46(3):353-64. doi: 10.1007/s10519-015-9750-6. Epub 2015 Oct 22.


High energy focused shock wave therapy accelerates bone healing. A blinded, prospective, randomized canine clinical trial.

Kieves NR, MacKay CS, Adducci K, Rao S, Goh C, Palmer RH, Duerr FM.

Vet Comp Orthop Traumatol. 2015;28(6):425-32. doi: 10.3415/VCOT-15-05-0084. Epub 2015 Oct 9.


FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase.

Guan J, Umapathy G, Yamazaki Y, Wolfstetter G, Mendoza P, Pfeifer K, Mohammed A, Hugosson F, Zhang H, Hsu AW, Halenbeck R, Hallberg B, Palmer RH.

Elife. 2015 Sep 29;4:e09811. doi: 10.7554/eLife.09811.


Microsphere-based gradient implants for osteochondral regeneration: a long-term study in sheep.

Mohan N, Gupta V, Sridharan BP, Mellott AJ, Easley JT, Palmer RH, Galbraith RA, Key VH, Berkland CJ, Detamore MS.

Regen Med. 2015;10(6):709-28. doi: 10.2217/rme.15.38. Epub 2015 Sep 29.


An initial investigation of associations between dopamine-linked genetic variation and smoking motives in African Americans.

Bidwell LC, McGeary JE, Gray JC, Palmer RH, Knopik VS, MacKillop J.

Pharmacol Biochem Behav. 2015 Nov;138:104-10. doi: 10.1016/j.pbb.2015.09.018. Epub 2015 Sep 26.


Missouri Mothers and Their Children: A Family Study of the Effects of Genetics and the Prenatal Environment.

Knopik VS, Heath AC, Marceau K, Palmer RH, McGeary JE, Todorov A, Evans AS.

Twin Res Hum Genet. 2015 Oct;18(5):485-96. doi: 10.1017/thg.2015.46. Epub 2015 Jul 29.


Shared additive genetic influences on DSM-IV criteria for alcohol dependence in subjects of European ancestry.

Palmer RH, McGeary JE, Heath AC, Keller MC, Brick LA, Knopik VS.

Addiction. 2015 Dec;110(12):1922-31. doi: 10.1111/add.13070. Epub 2015 Aug 22.

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