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Items: 31


Juvenile idiopathic arthritis and risk of cancer before and after the introduction of biological therapies.

Horne A, Delcoigne B, Palmblad K, Askling J.

RMD Open. 2019 Nov 13;5(2):e001055. doi: 10.1136/rmdopen-2019-001055. eCollection 2019.


Empowering Young People Living With Juvenile Idiopathic Arthritis to Better Communicate With Families and Care Teams: Content Analysis of Semistructured Interviews.

Grande SW, Longacre MR, Palmblad K, Montan MV, Berquist RP, Hager A, Kotzbauer G.

JMIR Mhealth Uhealth. 2019 Feb 22;7(2):e10401. doi: 10.2196/10401.


A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice.

Lundbäck P, Lea JD, Sowinska A, Ottosson L, Fürst CM, Steen J, Aulin C, Clarke JI, Kipar A, Klevenvall L, Yang H, Palmblad K, Park BK, Tracey KJ, Blom AM, Andersson U, Antoine DJ, Erlandsson Harris H.

Hepatology. 2016 Nov;64(5):1699-1710. doi: 10.1002/hep.28736. Epub 2016 Sep 1.


An in vivo cross-linkable hyaluronan gel with inherent anti-inflammatory properties reduces OA cartilage destruction in female mice subjected to cruciate ligament transection.

Aulin C, Lundbäck P, Palmblad K, Klareskog L, Erlandsson Harris H.

Osteoarthritis Cartilage. 2017 Jan;25(1):157-165. doi: 10.1016/j.joca.2016.08.011. Epub 2016 Aug 29.


High systemic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome.

Palmblad K, Schierbeck H, Sundberg E, Horne AC, Harris HE, Henter JI, Antoine DJ, Andersson U.

Mol Med. 2015 Jan 27;20:538-47. doi: 10.2119/molmed.2014.00183.


Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis.

Agalave NM, Larsson M, Abdelmoaty S, Su J, Baharpoor A, Lundbäck P, Palmblad K, Andersson U, Harris H, Svensson CI.

Pain. 2014 Sep;155(9):1802-13. doi: 10.1016/j.pain.2014.06.007. Epub 2014 Jun 20.


TLR4 as receptor for HMGB1 induced muscle dysfunction in myositis.

Zong M, Bruton JD, Grundtman C, Yang H, Li JH, Alexanderson H, Palmblad K, Andersson U, Harris HE, Lundberg IE, Westerblad H.

Ann Rheum Dis. 2013 Aug;72(8):1390-9. doi: 10.1136/annrheumdis-2012-202207. Epub 2012 Nov 12.


Pro-inflammatory cytokines produced by growth plate chondrocytes may act locally to modulate longitudinal bone growth.

Fernandez-Vojvodich P, Palmblad K, Karimian E, Andersson U, Sävendahl L.

Horm Res Paediatr. 2012;77(3):180-7. doi: 10.1159/000337569. Epub 2012 Apr 12.


Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis.

Zickert A, Palmblad K, Sundelin B, Chavan S, Tracey KJ, Bruchfeld A, Gunnarsson I.

Arthritis Res Ther. 2012 Feb 20;14(1):R36. doi: 10.1186/ar3747.


High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts.

Wähämaa H, Schierbeck H, Hreggvidsdottir HS, Palmblad K, Aveberger AC, Andersson U, Harris HE.

Arthritis Res Ther. 2011 Aug 26;13(4):R136. doi: 10.1186/ar3450.


Monoclonal anti-HMGB1 (high mobility group box chromosomal protein 1) antibody protection in two experimental arthritis models.

Schierbeck H, Lundbäck P, Palmblad K, Klevenvall L, Erlandsson-Harris H, Andersson U, Ottosson L.

Mol Med. 2011 Sep-Oct;17(9-10):1039-44. doi: 10.2119/molmed.2010.00264. Epub 2011 Jun 7.


High-mobility group box-1 protein (HMGB1) is increased in antineutrophilic cytoplasmatic antibody (ANCA)-associated vasculitis with renal manifestations.

Bruchfeld A, Wendt M, Bratt J, Qureshi AR, Chavan S, Tracey KJ, Palmblad K, Gunnarsson I.

Mol Med. 2011 Jan-Feb;17(1-2):29-35. doi: 10.2119/molmed.2010.00132. Epub 2010 Sep 10.


A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release.

Yang H, Hreggvidsdottir HS, Palmblad K, Wang H, Ochani M, Li J, Lu B, Chavan S, Rosas-Ballina M, Al-Abed Y, Akira S, Bierhaus A, Erlandsson-Harris H, Andersson U, Tracey KJ.

Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11942-7. doi: 10.1073/pnas.1003893107. Epub 2010 Jun 14.


Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model.

Ostberg T, Kawane K, Nagata S, Yang H, Chavan S, Klevenvall L, Bianchi ME, Harris HE, Andersson U, Palmblad K.

Arthritis Rheum. 2010 Oct;62(10):2963-72. doi: 10.1002/art.27590.


The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation.

Hreggvidsdottir HS, Ostberg T, Wähämaa H, Schierbeck H, Aveberger AC, Klevenvall L, Palmblad K, Ottosson L, Andersson U, Harris HE.

J Leukoc Biol. 2009 Sep;86(3):655-62. doi: 10.1189/jlb.0908548. Epub 2009 Jun 29.


Highly arthritis-susceptible DA rats express IL-1beta in articular cartilage.

Weiss RJ, Erlandsson Harris H, Palmblad K.

Scand J Immunol. 2009 Mar;69(3):188-93. doi: 10.1111/j.1365-3083.2008.02210.x.


High mobility group box chromosomal protein 1 acts as a proliferation signal for activated T lymphocytes.

Sundberg E, Fasth AE, Palmblad K, Harris HE, Andersson U.

Immunobiology. 2009;214(4):303-9. doi: 10.1016/j.imbio.2008.09.006. Epub 2008 Oct 25.


Gait pattern in rheumatoid arthritis.

Weiss RJ, Wretenberg P, Stark A, Palmblad K, Larsson P, Gröndal L, Broström E.

Gait Posture. 2008 Aug;28(2):229-34. doi: 10.1016/j.gaitpost.2007.12.001. Epub 2008 Jan 15.


Oxaliplatin retains HMGB1 intranuclearly and ameliorates collagen type II-induced arthritis.

Ostberg T, Wähämaa H, Palmblad K, Ito N, Stridh P, Shoshan M, Lotze MT, Harris HE, Andersson U.

Arthritis Res Ther. 2008;10(1):R1. doi: 10.1186/ar2347. Epub 2008 Jan 7.


The novel inflammatory cytokine high mobility group box protein 1 (HMGB1) is expressed by human term placenta.

Holmlund U, Wähämaa H, Bachmayer N, Bremme K, Sverremark-Ekström E, Palmblad K.

Immunology. 2007 Nov;122(3):430-7. Epub 2007 Jul 6.


Morphological characterization of intra-articular HMGB1 expression during the course of collagen-induced arthritis.

Palmblad K, Sundberg E, Diez M, Söderling R, Aveberger AC, Andersson U, Harris HE.

Arthritis Res Ther. 2007;9(2):R35.


Morphological characterization of receptor activator of NFkappaB ligand (RANKL) and IL-1beta expression in rodent collagen-induced arthritis.

Weiss RJ, Erlandsson Harris H, Wick MC, Wretenberg P, Stark A, Palmblad K.

Scand J Immunol. 2005 Jul;62(1):55-62.


Orthopaedic surgery of the lower limbs in 49,802 rheumatoid arthritis patients: results from the Swedish National Inpatient Registry during 1987 to 2001.

Weiss RJ, Stark A, Wick MC, Ehlin A, Palmblad K, Wretenberg P.

Ann Rheum Dis. 2006 Mar;65(3):335-41. Epub 2005 Aug 3.


Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity.

Lundberg K, Nijenhuis S, Vossenaar ER, Palmblad K, van Venrooij WJ, Klareskog L, Zendman AJ, Harris HE.

Arthritis Res Ther. 2005;7(3):R458-67. Epub 2005 Feb 21.


CNI-1493, an inhibitor of proinflammatory cytokines, retards cartilage destruction in rats with collagen induced arthritis.

Larsson E, Harris HE, Palmblad K, Månsson B, Saxne T, Klareskog L.

Ann Rheum Dis. 2005 Mar;64(3):494-6.


Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity.

Kokkola R, Li J, Sundberg E, Aveberger AC, Palmblad K, Yang H, Tracey KJ, Andersson U, Harris HE.

Arthritis Rheum. 2003 Jul;48(7):2052-8.


High mobility group box chromosomal protein 1: a novel proinflammatory mediator in synovitis.

Kokkola R, Sundberg E, Ulfgren AK, Palmblad K, Li J, Wang H, Ulloa L, Yang H, Yan XJ, Furie R, Chiorazzi N, Tracey KJ, Andersson U, Harris HE.

Arthritis Rheum. 2002 Oct;46(10):2598-603.


IFN-alpha beta-dependent, IFN-gamma secretion by bone marrow-derived macrophages controls an intracellular bacterial infection.

Rothfuchs AG, Gigliotti D, Palmblad K, Andersson U, Wigzell H, Rottenberg ME.

J Immunol. 2001 Dec 1;167(11):6453-61.


High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes.

Andersson U, Wang H, Palmblad K, Aveberger AC, Bloom O, Erlandsson-Harris H, Janson A, Kokkola R, Zhang M, Yang H, Tracey KJ.

J Exp Med. 2000 Aug 21;192(4):565-70.


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