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Items: 44

1.

p53 Function Is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma.

Wei Y, Maximov V, Morrissy SA, Taylor MD, Pallas DC, Kenney AM.

Mol Cancer Res. 2019 Jan;17(1):186-198. doi: 10.1158/1541-7786.MCR-18-0485. Epub 2018 Sep 17.

PMID:
30224541
2.

Protein phosphatase 2A is crucial for sarcomere organization in Caenorhabditis elegans striated muscle.

Qadota H, Matsunaga Y, Bagchi P, Lange KI, Carrier KJ, Pols WV, Swartzbaugh E, Wilson KJ, Srayko M, Pallas DC, Benian GM.

Mol Biol Cell. 2018 Aug 15;29(17):2084-2097. doi: 10.1091/mbc.E18-03-0192. Epub 2018 Jun 27.

3.

Global loss of leucine carboxyl methyltransferase-1 causes severe defects in fetal liver hematopoiesis.

Lee JA, Wang Z, Sambo D, Bunting KD, Pallas DC.

J Biol Chem. 2018 Jun 22;293(25):9636-9650. doi: 10.1074/jbc.RA118.002012. Epub 2018 May 7.

PMID:
29735529
5.

STRIPAK complexes: structure, biological function, and involvement in human diseases.

Hwang J, Pallas DC.

Int J Biochem Cell Biol. 2014 Feb;47:118-48. doi: 10.1016/j.biocel.2013.11.021. Epub 2013 Dec 11. Review.

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Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3.

Gordon J, Hwang J, Carrier KJ, Jones CA, Kern QL, Moreno CS, Karas RH, Pallas DC.

BMC Biochem. 2011 Oct 10;12:54. doi: 10.1186/1471-2091-12-54.

8.

The adenovirus E4orf4 protein induces G2/M arrest and cell death by blocking protein phosphatase 2A activity regulated by the B55 subunit.

Li S, Brignole C, Marcellus R, Thirlwell S, Binda O, McQuoid MJ, Ashby D, Chan H, Zhang Z, Miron MJ, Pallas DC, Branton PE.

J Virol. 2009 Sep;83(17):8340-52. doi: 10.1128/JVI.00711-09. Epub 2009 Jun 17.

9.

Cdc55p-mediated E4orf4 growth inhibition in Saccharomyces cerevisiae is mediated only in part via the catalytic subunit of protein phosphatase 2A.

Li Y, Wei H, Hsieh TC, Pallas DC.

J Virol. 2008 Apr;82(7):3612-23. doi: 10.1128/JVI.02435-07. Epub 2008 Jan 23.

10.

FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A.

Narayanan U, Nalavadi V, Nakamoto M, Pallas DC, Ceman S, Bassell GJ, Warren ST.

J Neurosci. 2007 Dec 26;27(52):14349-57.

11.

Leucine carboxyl methyltransferase-1 is necessary for normal progression through mitosis in mammalian cells.

Lee JA, Pallas DC.

J Biol Chem. 2007 Oct 19;282(42):30974-84. Epub 2007 Aug 27.

12.

Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation.

Morales PR, Dillehay DL, Moody SJ, Pallas DC, Pruett S, Allgood JC, Symolon H, Merrill AH Jr.

Drug Chem Toxicol. 2007;30(3):197-216.

PMID:
17613006
13.

Expression of protein phosphatase 2A mutants and silencing of the regulatory B alpha subunit induce a selective loss of acetylated and detyrosinated microtubules.

Nunbhakdi-Craig V, Schuechner S, Sontag JM, Montgomery L, Pallas DC, Juno C, Mudrak I, Ogris E, Sontag E.

J Neurochem. 2007 May;101(4):959-71. Epub 2007 Mar 23.

14.

An in vivo assay to quantify stable protein phosphatase 2A (PP2A) heterotrimeric species.

Gentry MS, Hallberg RL, Pallas DC.

Methods Mol Biol. 2007;365:71-83.

PMID:
17200555
15.

Synthesis of 1-deoxysphingosine derivatives with conformationally restricted pyrrolidinediol head groups.

Dougherty AM, McDonald FE, Liotta DC, Moody SJ, Pallas DC, Pack CD, Merrill AH.

Org Lett. 2006 Feb 16;8(4):649-52.

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Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha.

Lu Q, Pallas DC, Surks HK, Baur WE, Mendelsohn ME, Karas RH.

Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17126-31. Epub 2004 Nov 29.

18.

Signaling and transcriptional changes critical for transformation of human cells by simian virus 40 small tumor antigen or protein phosphatase 2A B56gamma knockdown.

Moreno CS, Ramachandran S, Ashby DG, Laycock N, Plattner CA, Chen W, Hahn WC, Pallas DC.

Cancer Res. 2004 Oct 1;64(19):6978-88.

19.

Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function.

Iida S, Hirota T, Morisaki T, Marumoto T, Hara T, Kuninaka S, Honda S, Kosai K, Kawasuji M, Pallas DC, Saya H.

Oncogene. 2004 Jul 8;23(31):5266-74.

PMID:
15122335
20.

Identification of specific PP2A complexes involved in human cell transformation.

Chen W, Possemato R, Campbell KT, Plattner CA, Pallas DC, Hahn WC.

Cancer Cell. 2004 Feb;5(2):127-36.

21.

Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A.

Shern JF, Sharer JD, Pallas DC, Bartolini F, Cowan NJ, Reed MS, Pohl J, Kahn RA.

J Biol Chem. 2003 Oct 17;278(42):40829-36. Epub 2003 Aug 11.

22.

Regulation of estrogen receptor alpha-mediated transcription by a direct interaction with protein phosphatase 2A.

Lu Q, Surks HK, Ebling H, Baur WE, Brown D, Pallas DC, Karas RH.

J Biol Chem. 2003 Feb 14;278(7):4639-45. Epub 2002 Dec 3.

23.

Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery.

Harada JN, Shevchenko A, Shevchenko A, Pallas DC, Berk AJ.

J Virol. 2002 Sep;76(18):9194-206.

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Serine 257 phosphorylation regulates association of polyomavirus middle T antigen with 14-3-3 proteins.

Culleré X, Rose P, Thathamangalam U, Chatterjee A, Mullane KP, Pallas DC, Benjamin TL, Roberts TM, Schaffhausen BS.

J Virol. 1998 Jan;72(1):558-63.

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Interaction of the protein kinase Raf-1 with 14-3-3 proteins.

Fu H, Xia K, Pallas DC, Cui C, Conroy K, Narsimhan RP, Mamon H, Collier RJ, Roberts TM.

Science. 1994 Oct 7;266(5182):126-9.

PMID:
7939632
34.

Association of polyomavirus middle tumor antigen with 14-3-3 proteins.

Pallas DC, Fu H, Haehnel LC, Weller W, Collier RJ, Roberts TM.

Science. 1994 Jul 22;265(5171):535-7.

PMID:
8036498
35.

Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen.

Campbell KS, Ogris E, Burke B, Su W, Auger KR, Druker BJ, Schaffhausen BS, Roberts TM, Pallas DC.

Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6344-8.

37.

Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product.

Kaelin WG Jr, Pallas DC, DeCaprio JA, Kaye FJ, Livingston DM.

Cell. 1991 Feb 8;64(3):521-32.

PMID:
1825028
38.

Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.

Pallas DC, Shahrik LK, Martin BL, Jaspers S, Miller TB, Brautigan DL, Roberts TM.

Cell. 1990 Jan 12;60(1):167-76.

PMID:
2153055
40.

Mechanisms of transformation by polyoma virus middle T antigen.

Kaplan DR, Pallas DC, Morgan W, Schaffhausen B, Roberts TM.

Biochim Biophys Acta. 1989 Feb;948(3):345-64. Review.

PMID:
2465782
41.

Cellular proteins that associate with the middle and small T antigens of polyomavirus.

Pallas DC, Cherington V, Morgan W, DeAnda J, Kaplan D, Schaffhausen B, Roberts TM.

J Virol. 1988 Nov;62(11):3934-40.

43.

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity.

Kaplan DR, Whitman M, Schaffhausen B, Pallas DC, White M, Cantley L, Roberts TM.

Cell. 1987 Sep 25;50(7):1021-9.

PMID:
2441878
44.

Polyomavirus small t antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody production.

Pallas DC, Schley C, Mahoney M, Harlow E, Schaffhausen BS, Roberts TM.

J Virol. 1986 Dec;60(3):1075-84.

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