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Items: 22

1.

Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin.

Fiaschi L, Di Palo B, Scarselli M, Pozzi C, Tomaszewski K, Galletti B, Nardi-Dei V, Arcidiacono L, Mishra RP, Mori E, Pallaoro M, Falugi F, Torre A, Fontana MR, Soriani M, Bubeck Wardenburg J, Grandi G, Rappuoli R, Ferlenghi I, Bagnoli F.

Clin Vaccine Immunol. 2016 Jun 6;23(6):442-50. doi: 10.1128/CVI.00091-16. Print 2016 Jun.

2.

One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A.

Mancini F, Monaci E, Lofano G, Torre A, Bacconi M, Tavarini S, Sammicheli C, Arcidiacono L, Galletti B, Laera D, Pallaoro M, Tuscano G, Fontana MR, Bensi G, Grandi G, Rossi-Paccani S, Nuti S, Rappuoli R, De Gregorio E, Bagnoli F, Soldaini E, Bertholet S.

PLoS One. 2016 Jan 26;11(1):e0147767. doi: 10.1371/journal.pone.0147767. eCollection 2016.

3.

Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2.

Ahmed SS, Volkmuth W, Duca J, Corti L, Pallaoro M, Pezzicoli A, Karle A, Rigat F, Rappuoli R, Narasimhan V, Julkunen I, Vuorela A, Vaarala O, Nohynek H, Pasini FL, Montomoli E, Trombetta C, Adams CM, Rothbard J, Steinman L.

Sci Transl Med. 2015 Jul 1;7(294):294ra105. doi: 10.1126/scitranslmed.aab2354.

PMID:
26136476
4.

Molecular Engineering of Ghfp, the Gonococcal Orthologue of Neisseria meningitidis Factor H Binding Protein.

Rippa V, Santini L, Lo Surdo P, Cantini F, Veggi D, Gentile MA, Grassi E, Iannello G, Brunelli B, Ferlicca F, Palmieri E, Pallaoro M, Aricò B, Banci L, Pizza M, Scarselli M.

Clin Vaccine Immunol. 2015 Jul;22(7):769-77. doi: 10.1128/CVI.00794-14. Epub 2015 May 6.

5.

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus.

Bagnoli F, Fontana MR, Soldaini E, Mishra RP, Fiaschi L, Cartocci E, Nardi-Dei V, Ruggiero P, Nosari S, De Falco MG, Lofano G, Marchi S, Galletti B, Mariotti P, Bacconi M, Torre A, Maccari S, Scarselli M, Rinaudo CD, Inoshima N, Savino S, Mori E, Rossi-Paccani S, Baudner B, Pallaoro M, Swennen E, Petracca R, Brettoni C, Liberatori S, Norais N, Monaci E, Bubeck Wardenburg J, Schneewind O, O'Hagan DT, Valiante NM, Bensi G, Bertholet S, De Gregorio E, Rappuoli R, Grandi G.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3680-5. doi: 10.1073/pnas.1424924112. Epub 2015 Mar 9.

6.

The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination.

Vono M, Taccone M, Caccin P, Gallotta M, Donvito G, Falzoni S, Palmieri E, Pallaoro M, Rappuoli R, Di Virgilio F, De Gregorio E, Montecucco C, Seubert A.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21095-100. doi: 10.1073/pnas.1319784110. Epub 2013 Dec 9.

7.

RrgB321, a fusion protein of the three variants of the pneumococcal pilus backbone RrgB, is protective in vivo and elicits opsonic antibodies.

Harfouche C, Filippini S, Gianfaldoni C, Ruggiero P, Moschioni M, Maccari S, Pancotto L, Arcidiacono L, Galletti B, Censini S, Mori E, Giuliani M, Facciotti C, Cartocci E, Savino S, Doro F, Pallaoro M, Nocadello S, Mancuso G, Haston M, Goldblatt D, Barocchi MA, Pizza M, Rappuoli R, Masignani V.

Infect Immun. 2012 Jan;80(1):451-60. doi: 10.1128/IAI.05780-11. Epub 2011 Nov 14.

8.

Rational design of a meningococcal antigen inducing broad protective immunity.

Scarselli M, Aricò B, Brunelli B, Savino S, Di Marcello F, Palumbo E, Veggi D, Ciucchi L, Cartocci E, Bottomley MJ, Malito E, Lo Surdo P, Comanducci M, Giuliani MM, Cantini F, Dragonetti S, Colaprico A, Doro F, Giannetti P, Pallaoro M, Brogioni B, Tontini M, Hilleringmann M, Nardi-Dei V, Banci L, Pizza M, Rappuoli R.

Sci Transl Med. 2011 Jul 13;3(91):91ra62. doi: 10.1126/scitranslmed.3002234.

9.

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88.

Seubert A, Calabro S, Santini L, Galli B, Genovese A, Valentini S, Aprea S, Colaprico A, D'Oro U, Giuliani MM, Pallaoro M, Pizza M, O'Hagan DT, Wack A, Rappuoli R, De Gregorio E.

Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11169-74. doi: 10.1073/pnas.1107941108. Epub 2011 Jun 20.

10.

A two-stage strategy for sterilization of poly(lactide-co-glycolide) particles by γ-irradiation does not impair their potency for vaccine delivery.

Jain S, Malyala P, Pallaoro M, Giuliani M, Petersen H, O'Hagan DT, Singh M.

J Pharm Sci. 2011 Feb;100(2):646-54. doi: 10.1002/jps.22306.

PMID:
20665902
11.

PP2A regulates HDAC4 nuclear import.

Paroni G, Cernotta N, Dello Russo C, Gallinari P, Pallaoro M, Foti C, Talamo F, Orsatti L, Steinkühler C, Brancolini C.

Mol Biol Cell. 2008 Feb;19(2):655-67. Epub 2007 Nov 28.

12.

Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling.

Illi B, Dello Russo C, Colussi C, Rosati J, Pallaoro M, Spallotta F, Rotili D, Valente S, Ragone G, Martelli F, Biglioli P, Steinkuhler C, Gallinari P, Mai A, Capogrossi MC, Gaetano C.

Circ Res. 2008 Jan 4;102(1):51-8. Epub 2007 Nov 1.

PMID:
17975112
13.

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases.

Lahm A, Paolini C, Pallaoro M, Nardi MC, Jones P, Neddermann P, Sambucini S, Bottomley MJ, Lo Surdo P, Carfí A, Koch U, De Francesco R, Steinkühler C, Gallinari P.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17335-40. Epub 2007 Oct 23.

14.

HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics.

Gallinari P, Di Marco S, Jones P, Pallaoro M, Steinkühler C.

Cell Res. 2007 Mar;17(3):195-211. Review.

15.

Mechanism of activation of human heparanase investigated by protein engineering.

Nardella C, Lahm A, Pallaoro M, Brunetti M, Vannini A, Steinkühler C.

Biochemistry. 2004 Feb 24;43(7):1862-73.

PMID:
14967027
16.

Reactivity of the NS2/3(907-1206)ASK(4) protein with beta-mercaptoethanol studied by electrospray ion trap mass spectrometry.

Orsatti L, Pallaoro M, Steinküler C, Orru' S, Bonelli F.

Rapid Commun Mass Spectrom. 2002;16(20):1919-27.

PMID:
12362382
17.

Characterization of the hepatitis C virus NS2/3 processing reaction by using a purified precursor protein.

Pallaoro M, Lahm A, Biasiol G, Brunetti M, Nardella C, Orsatti L, Bonelli F, Orrù S, Narjes F, Steinkühler C.

J Virol. 2001 Oct;75(20):9939-46.

18.

Role of charged residues in the catalytic mechanism of hepatitis C virus NS3 protease: electrostatic precollision guidance and transition-state stabilization.

Koch U, Biasiol G, Brunetti M, Fattori D, Pallaoro M, Steinkühler C.

Biochemistry. 2001 Jan 23;40(3):631-40.

PMID:
11170379
19.

Characterization of human gamma-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families.

Caughey GH, Raymond WW, Blount JL, Hau LW, Pallaoro M, Wolters PJ, Verghese GM.

J Immunol. 2000 Jun 15;164(12):6566-75.

20.

Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3.

Pallaoro M, Fejzo MS, Shayesteh L, Blount JL, Caughey GH.

J Biol Chem. 1999 Feb 5;274(6):3355-62.

21.

Structural and functional properties of Bos taurus tryptase: a search for a possible propeptide processing role.

Fiorucci L, Pallaoro M, Erba F, Colombo AP, Rholam M, Cohen P, Ascoli F.

Comp Biochem Physiol B Biochem Mol Biol. 1998 Jun;120(2):239-45.

PMID:
9787793
22.

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