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Items: 7

1.

Glycopeptides related to beta-endorphin adopt helical amphipathic conformations in the presence of lipid bilayers.

Dhanasekaran M, Palian MM, Alves I, Yeomans L, Keyari CM, Davis P, Bilsky EJ, Egleton RD, Yamamura HI, Jacobsen NE, Tollin G, Hruby VJ, Porreca F, Polt R.

J Am Chem Soc. 2005 Apr 20;127(15):5435-48.

PMID:
15826181
2.

Antinociceptive structure-activity studies with enkephalin-based opioid glycopeptides.

Elmagbari NO, Egleton RD, Palian MM, Lowery JJ, Schmid WR, Davis P, Navratilova E, Dhanasekaran M, Keyari CM, Yamamura HI, Porreca F, Hruby VJ, Polt R, Bilsky EJ.

J Pharmacol Exp Ther. 2004 Oct;311(1):290-7. Epub 2004 May 27.

PMID:
15166257
3.

Glycopeptide-membrane interactions: glycosyl enkephalin analogues adopt turn conformations by NMR and CD in amphipathic media.

Palian MM, Boguslavsky VI, O'Brien DF, Polt R.

J Am Chem Soc. 2003 May 14;125(19):5823-31.

PMID:
12733923
4.

Improved blood-brain barrier penetration and enhanced analgesia of an opioid peptide by glycosylation.

Egleton RD, Mitchell SA, Huber JD, Palian MM, Polt R, Davis TP.

J Pharmacol Exp Ther. 2001 Dec;299(3):967-72.

PMID:
11714884
5.

Lipo alpha-amino-beta-hydroxy acids and O-linked glycosides: building blocks for ceramyl and glycosphingoyl peptides.

Palian MM, Polt R.

J Org Chem. 2001 Oct 19;66(21):7178-83. No abstract available.

PMID:
11597248
6.

O-Linked glycopeptides retain helicity in water.

Palian MM, Jacobsen NE, Polt R.

J Pept Res. 2001 Aug;58(2):180-9.

PMID:
11532077
7.

Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability.

Bilsky EJ, Egleton RD, Mitchell SA, Palian MM, Davis P, Huber JD, Jones H, Yamamura HI, Janders J, Davis TP, Porreca F, Hruby VJ, Polt R.

J Med Chem. 2000 Jun 29;43(13):2586-90.

PMID:
10891118

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