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Items: 12


Efficacy of an Inhaled IL-13 Antibody Fragment in a Model of Chronic Asthma.

Lightwood D, Tservistas M, Zehentleitner M, Sarkar K, Turner A, Bracher M, Smith B, Lamour S, Bourne T, Shaw S, Gozzard N, Palframan RT.

Am J Respir Crit Care Med. 2018 Sep 1;198(5):610-619. doi: 10.1164/rccm.201712-2382OC.


Neutralisation of interleukin-13 in mice prevents airway pathology caused by chronic exposure to house dust mite.

Tomlinson KL, Davies GC, Sutton DJ, Palframan RT.

PLoS One. 2010 Oct 1;5(10). pii: e13136. doi: 10.1371/journal.pone.0013136.


In vitro and in vivo characterisation of anti-murine IL-13 antibodies recognising distinct functional epitopes.

Berry LM, Adams R, Airey M, Bracher MG, Bourne T, Carrington B, Cross AS, Davies GC, Finney HM, Foulkes R, Gozzard N, Griffin RA, Hailu H, Lamour SD, Lawson AD, Lightwood DJ, McKnight AJ, O'Dowd VL, Oxbrow AK, Popplewell AG, Shaw S, Stephens PE, Sweeney B, Tomlinson KL, Uhe C, Palframan RT.

Int Immunopharmacol. 2009 Feb;9(2):201-6. doi: 10.1016/j.intimp.2008.11.001. Epub 2008 Nov 27.


A novel endothelial L-selectin ligand activity in lymph node medulla that is regulated by alpha(1,3)-fucosyltransferase-IV.

M'Rini C, Cheng G, Schweitzer C, Cavanagh LL, Palframan RT, Mempel TR, Warnock RA, Lowe JB, Quackenbush EJ, von Andrian UH.

J Exp Med. 2003 Nov 3;198(9):1301-12.


Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues.

Palframan RT, Jung S, Cheng G, Weninger W, Luo Y, Dorf M, Littman DR, Rollins BJ, Zweerink H, Rot A, von Andrian UH.

J Exp Med. 2001 Nov 5;194(9):1361-73.


Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo.

Shimaoka M, Lu C, Palframan RT, von Andrian UH, McCormack A, Takagi J, Springer TA.

Proc Natl Acad Sci U S A. 2001 May 22;98(11):6009-14. Epub 2001 May 15.


The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment.

Baekkevold ES, Yamanaka T, Palframan RT, Carlsen HS, Reinholt FP, von Andrian UH, Brandtzaeg P, Haraldsen G.

J Exp Med. 2001 May 7;193(9):1105-12.


Eotaxin induces a rapid release of eosinophils and their progenitors from the bone marrow.

Palframan RT, Collins PD, Williams TJ, Rankin SM.

Blood. 1998 Apr 1;91(7):2240-8.


Kinetics of eotaxin generation and its relationship to eosinophil accumulation in allergic airways disease: analysis in a guinea pig model in vivo.

Humbles AA, Conroy DM, Marleau S, Rankin SM, Palframan RT, Proudfoot AE, Wells TN, Li D, Jeffery PK, Griffiths-Johnson DA, Williams TJ, Jose PJ.

J Exp Med. 1997 Aug 18;186(4):601-12.


The role of the eosinophil-selective chemokine, eotaxin, in allergic and non-allergic airways inflammation.

Conroy DM, Humbles AA, Rankin SM, Palframan RT, Collins PD, Griffiths-Johnson DA, Jose PJ, Williams TJ.

Mem Inst Oswaldo Cruz. 1997;92 Suppl 2:183-91. Review.


The effect of a tachykinin NK1 receptor antagonist, SR140333, on oedema formation induced in rat skin by venom from the Phoneutria nigriventer spider.

Palframan RT, Costa SK, Wilsoncroft P, Antunes E, de Nucci G, Brain SD.

Br J Pharmacol. 1996 May;118(2):295-8.

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