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Items: 31

1.

Protective effect of a locked retinal chromophore analogue against light-induced retinal degeneration.

Gao S, Parmar T, Palczewska G, Dong Z, Golczak M, Palczewski K, Jastrzebska B.

Mol Pharmacol. 2018 Jul 17. pii: mol.118.112581. doi: 10.1124/mol.118.112581. [Epub ahead of print]

2.

Multimodal nonlinear optical imaging of unstained retinas in the epi-direction with a sub-40 fs Yb-fiber laser.

Murashova GA, Mancuso CA, Canfield JL, Sakami S, Palczewski K, Palczewska G, Dantus M.

Biomed Opt Express. 2017 Oct 26;8(11):5228-5242. doi: 10.1364/BOE.8.005228. eCollection 2017 Nov 1.

3.

Epi-direction detected multimodal imaging of an unstained mouse retina with a Yb-fiber laser.

Murashova GA, Mancuso CA, Sakami S, Palczewski K, Palczewska G, Dantus M.

Proc SPIE Int Soc Opt Eng. 2017 Mar;10069. pii: 100692K. doi: 10.1117/12.2252457.

4.

Vision science and adaptive optics, the state of the field.

Marcos S, Werner JS, Burns SA, Merigan WH, Artal P, Atchison DA, Hampson KM, Legras R, Lundstrom L, Yoon G, Carroll J, Choi SS, Doble N, Dubis AM, Dubra A, Elsner A, Jonnal R, Miller DT, Paques M, Smithson HE, Young LK, Zhang Y, Campbell M, Hunter J, Metha A, Palczewska G, Schallek J, Sincich LC.

Vision Res. 2017 Mar;132:3-33. doi: 10.1016/j.visres.2017.01.006. Epub 2017 Feb 27. Review.

5.

Formation and Clearance of All-Trans-Retinol in Rods Investigated in the Living Primate Eye With Two-Photon Ophthalmoscopy.

Sharma R, Schwarz C, Hunter JJ, Palczewska G, Palczewski K, Williams DR.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):604-613. doi: 10.1167/iovs.16-20061.

6.

Safety assessment in macaques of light exposures for functional two-photon ophthalmoscopy in humans.

Schwarz C, Sharma R, Fischer WS, Chung M, Palczewska G, Palczewski K, Williams DR, Hunter JJ.

Biomed Opt Express. 2016 Nov 16;7(12):5148-5169. doi: 10.1364/BOE.7.005148. eCollection 2016 Dec 1.

7.

Receptor MER Tyrosine Kinase Proto-oncogene (MERTK) Is Not Required for Transfer of Bis-retinoids to the Retinal Pigmented Epithelium.

Palczewska G, Maeda A, Golczak M, Arai E, Dong Z, Perusek L, Kevany B, Palczewski K.

J Biol Chem. 2016 Dec 23;291(52):26937-26949. doi: 10.1074/jbc.M116.764563. Epub 2016 Nov 14.

8.

Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration.

Chen Y, Palczewska G, Masuho I, Gao S, Jin H, Dong Z, Gieser L, Brooks MJ, Kiser PD, Kern TS, Martemyanov KA, Swaroop A, Palczewski K.

Sci Signal. 2016 Jul 26;9(438):ra74. doi: 10.1126/scisignal.aag0245.

9.

Image registration and averaging of low laser power two-photon fluorescence images of mouse retina.

Alexander NS, Palczewska G, Stremplewski P, Wojtkowski M, Kern TS, Palczewski K.

Biomed Opt Express. 2016 Jun 20;7(7):2671-91. doi: 10.1364/BOE.7.002671. eCollection 2016 Jul 1.

10.

In Vivo Two-Photon Fluorescence Kinetics of Primate Rods and Cones.

Sharma R, Schwarz C, Williams DR, Palczewska G, Palczewski K, Hunter JJ.

Invest Ophthalmol Vis Sci. 2016 Feb;57(2):647-57. doi: 10.1167/iovs.15-17946.

11.

Two-Photon Autofluorescence Imaging Reveals Cellular Structures Throughout the Retina of the Living Primate Eye.

Sharma R, Williams DR, Palczewska G, Palczewski K, Hunter JJ.

Invest Ophthalmol Vis Sci. 2016 Feb;57(2):632-46. doi: 10.1167/iovs.15-17961.

12.

Periscope for noninvasive two-photon imaging of murine retina in vivo.

Stremplewski P, Komar K, Palczewski K, Wojtkowski M, Palczewska G.

Biomed Opt Express. 2015 Aug 13;6(9):3352-61. doi: 10.1364/BOE.6.003352. eCollection 2015 Sep 1.

13.

Semi-automated discrimination of retinal pigmented epithelial cells in two-photon fluorescence images of mouse retinas.

Alexander NS, Palczewska G, Palczewski K.

Biomed Opt Express. 2015 Jul 23;6(8):3032-52. doi: 10.1364/BOE.6.003032. eCollection 2015 Aug 1.

14.

Molecular pharmacodynamics of emixustat in protection against retinal degeneration.

Zhang J, Kiser PD, Badiee M, Palczewska G, Dong Z, Golczak M, Tochtrop GP, Palczewski K.

J Clin Invest. 2015 Jul 1;125(7):2781-94. doi: 10.1172/JCI80950. Epub 2015 Jun 15.

15.

Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.

Zhang N, Tsybovsky Y, Kolesnikov AV, Rozanowska M, Swider M, Schwartz SB, Stone EM, Palczewska G, Maeda A, Kefalov VJ, Jacobson SG, Cideciyan AV, Palczewski K.

Hum Mol Genet. 2015 Jun 1;24(11):3220-37. doi: 10.1093/hmg/ddv073. Epub 2015 Feb 24.

16.

Imaging of rhodopsin crystals with two-photon microscopy.

Palczewska G, Salom D.

Methods Mol Biol. 2015;1271:55-64. doi: 10.1007/978-1-4939-2330-4_4.

PMID:
25697516
17.

Human infrared vision is triggered by two-photon chromophore isomerization.

Palczewska G, Vinberg F, Stremplewski P, Bircher MP, Salom D, Komar K, Zhang J, Cascella M, Wojtkowski M, Kefalov VJ, Palczewski K.

Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):E5445-54. doi: 10.1073/pnas.1410162111. Epub 2014 Dec 1.

18.

Endogenous fluorophores enable two-photon imaging of the primate eye.

Palczewska G, Golczak M, Williams DR, Hunter JJ, Palczewski K.

Invest Ophthalmol Vis Sci. 2014 Jun 26;55(7):4438-47. doi: 10.1167/iovs.14-14395.

19.

Noninvasive two-photon microscopy imaging of mouse retina and retinal pigment epithelium through the pupil of the eye.

Palczewska G, Dong Z, Golczak M, Hunter JJ, Williams DR, Alexander NS, Palczewski K.

Nat Med. 2014 Jul;20(7):785-9. doi: 10.1038/nm.3590. Epub 2014 Jun 22.

20.

Two-photon microscopy reveals early rod photoreceptor cell damage in light-exposed mutant mice.

Maeda A, Palczewska G, Golczak M, Kohno H, Dong Z, Maeda T, Palczewski K.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):E1428-37. doi: 10.1073/pnas.1317986111. Epub 2014 Mar 24.

21.

Systems pharmacology identifies drug targets for Stargardt disease-associated retinal degeneration.

Chen Y, Palczewska G, Mustafi D, Golczak M, Dong Z, Sawada O, Maeda T, Maeda A, Palczewski K.

J Clin Invest. 2013 Dec;123(12):5119-34. doi: 10.1172/JCI69076. Epub 2013 Nov 15.

22.

Retinal pigmented epithelial cells obtained from human induced pluripotent stem cells possess functional visual cycle enzymes in vitro and in vivo.

Maeda T, Lee MJ, Palczewska G, Marsili S, Tesar PJ, Palczewski K, Takahashi M, Maeda A.

J Biol Chem. 2013 Nov 29;288(48):34484-93. doi: 10.1074/jbc.M113.518571. Epub 2013 Oct 15.

23.

In vivo two-photon imaging of the mouse retina.

Sharma R, Yin L, Geng Y, Merigan WH, Palczewska G, Palczewski K, Williams DR, Hunter JJ.

Biomed Opt Express. 2013 Jul 9;4(8):1285-93. doi: 10.1364/BOE.4.001285. eCollection 2013.

24.

QLT091001, a 9-cis-retinal analog, is well-tolerated by retinas of mice with impaired visual cycles.

Maeda T, Dong Z, Jin H, Sawada O, Gao S, Utkhede D, Monk W, Palczewska G, Palczewski K.

Invest Ophthalmol Vis Sci. 2013 Jan 17;54(1):455-66. doi: 10.1167/iovs.12-11152.

25.

Ultrasound characterization of middle ear effusion.

Seth R, Discolo CM, Palczewska GM, Lewandowski JJ, Krakovitz PR.

Am J Otolaryngol. 2013 Jan-Feb;34(1):44-50. doi: 10.1016/j.amjoto.2012.08.005. Epub 2012 Oct 17.

26.

Imaging of protein crystals with two-photon microscopy.

Padayatti P, Palczewska G, Sun W, Palczewski K, Salom D.

Biochemistry. 2012 Feb 28;51(8):1625-37. doi: 10.1021/bi201682q. Epub 2012 Feb 16.

27.

Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage.

Okano K, Maeda A, Chen Y, Chauhan V, Tang J, Palczewska G, Sakai T, Tsuneoka H, Palczewski K, Maeda T.

J Neurochem. 2012 Apr;121(1):146-56. doi: 10.1111/j.1471-4159.2012.07647.x. Epub 2012 Feb 9.

28.

Primary amines protect against retinal degeneration in mouse models of retinopathies.

Maeda A, Golczak M, Chen Y, Okano K, Kohno H, Shiose S, Ishikawa K, Harte W, Palczewska G, Maeda T, Palczewski K.

Nat Chem Biol. 2011 Dec 25;8(2):170-8. doi: 10.1038/nchembio.759.

29.

Retinyl ester storage particles (retinosomes) from the retinal pigmented epithelium resemble lipid droplets in other tissues.

Orban T, Palczewska G, Palczewski K.

J Biol Chem. 2011 May 13;286(19):17248-58. doi: 10.1074/jbc.M110.195198. Epub 2011 Mar 25.

30.

Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy.

Hunter JJ, Masella B, Dubra A, Sharma R, Yin L, Merigan WH, Palczewska G, Palczewski K, Williams DR.

Biomed Opt Express. 2010 Dec 17;2(1):139-48. doi: 10.1364/BOE.2.000139.

31.

Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes.

Palczewska G, Maeda T, Imanishi Y, Sun W, Chen Y, Williams DR, Piston DW, Maeda A, Palczewski K.

Nat Med. 2010 Dec;16(12):1444-9. doi: 10.1038/nm.2260. Epub 2010 Nov 14.

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