Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 111

1.

Parasitic infectious diseases.

Palacios F, Alonso C.

Eur J Med Chem. 2020 Mar 10;193:112230. doi: 10.1016/j.ejmech.2020.112230. [Epub ahead of print] No abstract available.

PMID:
32199133
2.

A methodology based on multiple criteria decision analysis for combining antibiotics in empirical therapy.

Campos M, Jimenez F, Sanchez G, Juarez JM, Morales A, Canovas-Segura B, Palacios F.

Artif Intell Med. 2020 Jan;102:101751. doi: 10.1016/j.artmed.2019.101751. Epub 2019 Nov 13.

PMID:
31980090
3.

Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia.

Podaza E, Palacios F, Croci DO, Risnik D, Yan XJ, Almejún MB, Colado A, Elías EE, Borge M, Morande PE, Bezares R, Fernández-Grecco H, Rabinovich GA, Gamberale R, Chiorazzi N, Giordano M.

Haematologica. 2020 Jan 16. pii: haematol.2019.227975. doi: 10.3324/haematol.2019.227975. [Epub ahead of print] No abstract available.

4.

New Challenges in Drug Discovery - July 8-11, 2019, Vitoria-Gasteiz, Spain.

Alonso C, de Los Santos JM, Palacios F.

ChemMedChem. 2020 Jan 7;15(1):168-171. doi: 10.1002/cmdc.201900627. Epub 2019 Nov 19.

PMID:
31743611
5.

Enantioselective Aza-Reformatsky Reaction with Ketimines.

Maestro A, Martinez de Marigorta E, Palacios F, Vicario J.

Org Lett. 2019 Dec 6;21(23):9473-9477. doi: 10.1021/acs.orglett.9b03669. Epub 2019 Nov 15.

PMID:
31729883
6.

First synthesis of merged hybrids phosphorylated azirino[2,1-b]benzo[e][1,3]oxazine derivatives as anticancer agents.

Carramiñana V, Ochoa de Retana AM, de Los Santos JM, Palacios F.

Eur J Med Chem. 2020 Jan 1;185:111771. doi: 10.1016/j.ejmech.2019.111771. Epub 2019 Oct 19.

PMID:
31671309
7.

A Non-Invasive Method Based on Computer Vision for Grapevine Cluster Compactness Assessment Using a Mobile Sensing Platform under Field Conditions.

Palacios F, Diago MP, Tardaguila J.

Sensors (Basel). 2019 Sep 2;19(17). pii: E3799. doi: 10.3390/s19173799.

8.

A Brønsted Acid-Catalyzed Multicomponent Reaction for the Synthesis of Highly Functionalized γ-Lactam Derivatives.

Corte XD, Marigorta EM, Palacios F, Vicario J.

Molecules. 2019 Aug 14;24(16). pii: E2951. doi: 10.3390/molecules24162951.

9.

Straightforward synthesis and biological evaluation as topoisomerase I inhibitors and antiproliferative agents of hybrid Chromeno[4,3-b][1,5]Naphthyridines and Chromeno[4,3-b][1,5]Naphthyridin-6-ones.

Martín-Encinas E, Rubiales G, Knudssen BR, Palacios F, Alonso C.

Eur J Med Chem. 2019 Sep 15;178:752-766. doi: 10.1016/j.ejmech.2019.06.032. Epub 2019 Jun 14.

PMID:
31229877
10.

Multicomponent reactions (MCRs): a useful access to the synthesis of benzo-fused γ-lactams.

de Marigorta EM, Santos JML, Ochoa de Retana AM, Vicario J, Palacios F.

Beilstein J Org Chem. 2019 May 8;15:1065-1085. doi: 10.3762/bjoc.15.104. eCollection 2019. Review.

11.

Impact of expert knowledge on the detection of patients at risk of antimicrobial therapy failure by clinical decision support systems.

Cánovas-Segura B, Morales A, Juarez JM, Campos M, Palacios F.

J Biomed Inform. 2019 Jun;94:103200. doi: 10.1016/j.jbi.2019.103200. Epub 2019 May 6.

PMID:
31071456
12.

Synthesis and biological evaluation of cyanoaziridine phosphine oxides and phosphonates with antiproliferative activity.

Carramiñana V, Ochoa de Retana AM, Vélez Del Burgo A, de Los Santos JM, Palacios F.

Eur J Med Chem. 2019 Feb 1;163:736-746. doi: 10.1016/j.ejmech.2018.12.002. Epub 2018 Dec 3.

PMID:
30576904
13.

Enantioselective α-Aminophosphonate Functionalization of Indole Ring through an Organocatalyzed Friedel-Crafts Reaction.

Maestro A, Martinez de Marigorta E, Palacios F, Vicario J.

J Org Chem. 2019 Jan 18;84(2):1094-1102. doi: 10.1021/acs.joc.8b02843. Epub 2019 Jan 7.

PMID:
30557510
14.

Recent advances of the Povarov reaction in medicinal chemistry.

Ghashghaei O, Masdeu C, Alonso C, Palacios F, Lavilla R.

Drug Discov Today Technol. 2018 Nov;29:71-79. doi: 10.1016/j.ddtec.2018.08.004. Epub 2018 Aug 28. Review.

PMID:
30471676
15.

Antileishmanial activity of new hybrid tetrahydroquinoline and quinoline derivatives with phosphorus substituents.

Tejería A, Pérez-Pertejo Y, Reguera RM, Carbajo-Andrés R, Balaña-Fouce R, Alonso C, Martin-Encinas E, Selas A, Rubiales G, Palacios F.

Eur J Med Chem. 2019 Jan 15;162:18-31. doi: 10.1016/j.ejmech.2018.10.065. Epub 2018 Oct 31.

PMID:
30408746
16.

Synthesis of novel antiproliferative hybrid bis-(3-indolyl)methane phosphonate derivatives.

Maestro A, Martín-Encinas E, Alonso C, Martinez de Marigorta E, Rubiales G, Vicario J, Palacios F.

Eur J Med Chem. 2018 Oct 5;158:874-883. doi: 10.1016/j.ejmech.2018.09.011. Epub 2018 Sep 15.

PMID:
30253344
17.

A decision support system for antibiotic prescription based on local cumulative antibiograms.

Morales A, Campos M, Juarez JM, Canovas-Segura B, Palacios F, Marin R.

J Biomed Inform. 2018 Aug;84:114-122. doi: 10.1016/j.jbi.2018.07.003. Epub 2018 Jul 5.

18.

Substituted 1,5-naphthyridine derivatives as novel antileishmanial agents. Synthesis and biological evaluation.

Tejería A, Pérez-Pertejo Y, Reguera RM, Balaña-Fouce R, Alonso C, González M, Rubiales G, Palacios F.

Eur J Med Chem. 2018 May 25;152:137-147. doi: 10.1016/j.ejmech.2018.04.033. Epub 2018 Apr 18.

PMID:
29704722
19.

Novel topoisomerase I inhibitors. Syntheses and biological evaluation of phosphorus substituted quinoline derivates with antiproliferative activity.

Alonso C, Fuertes M, Martín-Encinas E, Selas A, Rubiales G, Tesauro C, Knudssen BK, Palacios F.

Eur J Med Chem. 2018 Apr 10;149:225-237. doi: 10.1016/j.ejmech.2018.02.058. Epub 2018 Feb 22.

PMID:
29501943
20.

Brönsted-Acid-Catalyzed Asymmetric Three-Component Reaction of Amines, Aldehydes, and Pyruvate Derivatives. Enantioselective Synthesis of Highly Functionalized γ-Lactam Derivatives.

Del Corte X, Maestro A, Vicario J, Martinez de Marigorta E, Palacios F.

Org Lett. 2018 Jan 19;20(2):317-320. doi: 10.1021/acs.orglett.7b03397. Epub 2017 Dec 28.

PMID:
29282981
21.

Seasonal Terpene Variation in Needles of Pinus radiata (Pinales: Pinaceae) Trees Attacked by Tomicus piniperda (Coleoptera: Scolytinae) and the Effect of Limonene on Beetle Aggregation.

Romón P, Aparicio D, Palacios F, Iturrondobeitia JC, Hance T, Goldarazena A.

J Insect Sci. 2017 Sep 1;17(5). doi: 10.1093/jisesa/iex066.

22.

[Efficacy and safety of the endoscopic management of Zenker diverticulum with IT-Knife 2 device].

Tenorio L, Palacios F.

Rev Gastroenterol Peru. 2017 Jul-Sep;37(3):203-208. Spanish.

PMID:
29093582
23.

Study of the Hetero-[4+2]-Cycloaddition Reaction of Aldimines and Alkynes. Synthesis of 1,5-Naphthyridine and Isoindolone Derivatives.

Alonso C, González M, Palacios F, Rubiales G.

J Org Chem. 2017 Jun 16;82(12):6379-6387. doi: 10.1021/acs.joc.7b00977. Epub 2017 Jun 5.

PMID:
28537387
24.

Medical Treatment for Postthrombotic Syndrome.

Palacios FS, Rathbun SW.

Semin Intervent Radiol. 2017 Mar;34(1):61-67. doi: 10.1055/s-0036-1597765. Review.

25.

Advantages of an optical nanosensor system for the mechanistic analysis of a novel topoisomerase I targeting drug: a case study.

Andersen MB, Tesauro C, Gonzalez M, Kristoffersen EL, Alonso C, Rubiales G, Coletta A, Frøhlich R, Stougaard M, Ho YP, Palacios F, Knudsen BR.

Nanoscale. 2017 Feb 2;9(5):1886-1895. doi: 10.1039/c6nr06848k.

PMID:
28094391
26.

Reaction of phosphinylated nitrosoalkenes with electron-rich heterocycles. Electrophilic aromatic substitution vs. cycloaddition.

de Los Santos JM, Rubiales G, Sbai ZE, Ochoa de Retana AM, Palacios F.

Org Biomol Chem. 2017 Jan 18;15(3):662-671. doi: 10.1039/c6ob02486f.

PMID:
27976778
27.

Progress toward the Development of a NEAT Protein Vaccine for Anthrax Disease.

Balderas MA, Nguyen CT, Terwilliger A, Keitel WA, Iniguez A, Torres R, Palacios F, Goulding CW, Maresso AW.

Infect Immun. 2016 Nov 18;84(12):3408-3422. Print 2016 Dec.

28.

Antileishmanial effect of new indeno-1,5-naphthyridines, selective inhibitors of Leishmania infantum type IB DNA topoisomerase.

Tejería A, Pérez-Pertejo Y, Reguera RM, Balaña-Fouce R, Alonso C, Fuertes M, González M, Rubiales G, Palacios F.

Eur J Med Chem. 2016 Nov 29;124:740-749. doi: 10.1016/j.ejmech.2016.09.017. Epub 2016 Sep 9.

PMID:
27639365
29.

Synthesis and biological evaluation of indeno[1,5]naphthyridines as topoisomerase I (TopI) inhibitors with antiproliferative activity.

Alonso C, Fuertes M, González M, Rubiales G, Tesauro C, Knudsen BR, Palacios F.

Eur J Med Chem. 2016 Jun 10;115:179-90. doi: 10.1016/j.ejmech.2016.03.031. Epub 2016 Mar 14.

PMID:
27017547
30.

Reaction of 2H-Azirine-Phosphine Oxides and -Phosphonates with Enolates Derived from β-Keto Esters.

Vélez Del Burgo A, Ochoa de Retana AM, de Los Santos JM, Palacios F.

J Org Chem. 2016 Jan 4;81(1):100-8. doi: 10.1021/acs.joc.5b02347. Epub 2015 Dec 17.

PMID:
26640969
31.

Carbon trifluoromethylation reactions of hydrocarbon derivatives and heteroarenes.

Alonso C, Martínez de Marigorta E, Rubiales G, Palacios F.

Chem Rev. 2015 Feb 25;115(4):1847-935. doi: 10.1021/cr500368h. Epub 2015 Jan 30. Review. No abstract available.

PMID:
25635524
32.

Synthesis and biological evaluation of 1,5-naphthyridines as topoisomerase I inhibitors. A new family of antiproliferative agents.

Alonso C, Fuertes M, González M, Rodríguez-Gascón A, Rubiales G, Palacios F.

Curr Top Med Chem. 2014;14(23):2722-8.

PMID:
25515747
33.

Dissecting chronic lymphocytic leukemia microenvironment signals in patients with unmutated disease: microRNA-22 regulates phosphatase and tensin homolog/AKT/FOXO1 pathway in proliferative leukemic cells.

Palacios F, Prieto D, Abreu C, Ruiz S, Morande P, Fernández-Calero T, Libisch G, Landoni AI, Oppezzo P.

Leuk Lymphoma. 2015 May;56(5):1560-5. doi: 10.3109/10428194.2014.990900. Epub 2015 Jan 29.

PMID:
25430416
34.

Asymmetric Synthesis of Functionalized Tetrasubstituted α-Aminophosphonates through Enantioselective Aza-Henry Reaction of Phosphorylated Ketimines.

Vicario J, Ortiz P, Ezpeleta JM, Palacios F.

J Org Chem. 2015 Jan 2;80(1):156-64. doi: 10.1021/jo502233m. Epub 2014 Dec 9.

PMID:
25422859
35.

Hetero-Diels-Alder reaction of phosphorylated nitroso alkenes with enol ethers on water: a clean approach toward 1,2-oxazine derivatives.

de Los Santos JM, Ignacio R, Es Sbai Z, Aparicio D, Palacios F.

J Org Chem. 2014 Aug 15;79(16):7607-15. doi: 10.1021/jo501339c. Epub 2014 Jul 31.

PMID:
25062501
36.

Activation of the PI3K/AKT pathway by microRNA-22 results in CLL B-cell proliferation.

Palacios F, Abreu C, Prieto D, Morande P, Ruiz S, Fernández-Calero T, Naya H, Libisch G, Robello C, Landoni AI, Gabus R, Dighiero G, Oppezzo P.

Leukemia. 2015 Jan;29(1):115-25. doi: 10.1038/leu.2014.158. Epub 2014 May 14.

PMID:
24825182
37.

Fluoroalkylated α,β-unsaturated imines as synthons for the preparation of fluorinated triazinane-2,4-diones and dihydropyrimidin-2(1H)-ones.

Fernández de Trocóniz G, Ochoa de Retana AM, Rubiales G, Palacios F.

J Org Chem. 2014 Jun 6;79(11):5173-81. doi: 10.1021/jo500745u. Epub 2014 May 13.

PMID:
24803029
38.

Intrahepatic cholangiocarcinoma or mixed hepatocellular-cholangiocarcinoma in patients undergoing liver transplantation: a Spanish matched cohort multicenter study.

Sapisochin G, de Lope CR, Gastaca M, de Urbina JO, López-Andujar R, Palacios F, Ramos E, Fabregat J, Castroagudín JF, Varo E, Pons JA, Parrilla P, González-Diéguez ML, Rodriguez M, Otero A, Vazquez MA, Zozaya G, Herrero JI, Antolin GS, Perez B, Ciria R, Rufian S, Fundora Y, Ferron JA, Guiberteau A, Blanco G, Varona MA, Barrera MA, Suarez MA, Santoyo J, Bruix J, Charco R.

Ann Surg. 2014 May;259(5):944-52. doi: 10.1097/SLA.0000000000000494.

PMID:
24441817
39.

"Very early" intrahepatic cholangiocarcinoma in cirrhotic patients: should liver transplantation be reconsidered in these patients?

Sapisochin G, Rodríguez de Lope C, Gastaca M, Ortiz de Urbina J, Suarez MA, Santoyo J, Castroagudín JF, Varo E, López-Andujar R, Palacios F, Sanchez Antolín G, Perez B, Guiberteau A, Blanco G, González-Diéguez ML, Rodriguez M, Varona MA, Barrera MA, Fundora Y, Ferron JA, Ramos E, Fabregat J, Ciria R, Rufian S, Otero A, Vazquez MA, Pons JA, Parrilla P, Zozaya G, Herrero JI, Charco R, Bruix J.

Am J Transplant. 2014 Mar;14(3):660-7. doi: 10.1111/ajt.12591. Epub 2014 Jan 10.

40.

The Neber approach to 2-(tetrazol-5-yl)-2H-azirines.

Cardoso AL, Gimeno L, Lemos A, Palacios F, Pinho e Melo TM.

J Org Chem. 2013 Jul 19;78(14):6983-91. doi: 10.1021/jo4006552. Epub 2013 Jul 3.

PMID:
23790021
41.

Methylation status regulates lipoprotein lipase expression in chronic lymphocytic leukemia.

Abreu C, Moreno P, Palacios F, Borge M, Morande P, Landoni AI, Gabus R, Dighiero G, Giordano M, Gamberale R, Oppezzo P.

Leuk Lymphoma. 2013 Aug;54(8):1844-8. doi: 10.3109/10428194.2013.796057. Epub 2013 Jun 21.

PMID:
23614796
42.

Synthesis of fluorinated β-aminophosphonates and γ-lactams.

Alonso C, González M, Fuertes M, Rubiales G, Ezpeleta JM, Palacios F.

J Org Chem. 2013 Apr 19;78(8):3858-66. doi: 10.1021/jo400281e. Epub 2013 Mar 22.

PMID:
23485177
43.

[Hypotension and ST-segment depression in response to disulfiram-ethanol].

López-Cuenca S, González-Gómez A, Martín-Pellicer A, Fraile-Sanz A, Pastor A, Palacios F.

Med Intensiva. 2013 Oct;37(7):495-6. doi: 10.1016/j.medin.2012.10.001. Epub 2012 Nov 15. Spanish. No abstract available.

44.

Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment.

Moreno P, Abreu C, Borge M, Palacios F, Morande P, Pegazzano M, Bianchi S, Landoni AI, Agrelo R, Giordano M, Dighiero G, Gamberale R, Oppezzo P.

Leukemia. 2013 Mar;27(3):721-5. doi: 10.1038/leu.2012.212. Epub 2012 Jul 25. No abstract available.

PMID:
22828442
45.

Quick diagnosis units or conventional hospitalisation for the diagnostic evaluation of severe anaemia: a paradigm shift in public health systems?

Bosch X, Palacios F, Inclán-Iríbar G, Castañeda M, Jordán A, Moreno P, Coca A, López-Soto A.

Eur J Intern Med. 2012 Mar;23(2):159-64. doi: 10.1016/j.ejim.2011.02.013. Epub 2011 Mar 12.

PMID:
22284247
47.

[Use of cyanoacrylate in the endoscopic therapy of gastric varices: experience in the National Hospital Edgardo Rebagliati Martins from 2006 to 2010].

Castillo O, Palacios F, Yoza M, Contardo C, Soriano C.

Rev Gastroenterol Peru. 2011 Jul-Sep;31(3):208-15. Spanish.

PMID:
22086314
48.

Selective synthesis of substituted pyrrole-2-phosphine oxides and -phosphonates from 2H-azirines and enolates from acetyl acetates and malonates.

Palacios F, Ochoa de Retana AM, Vélez del Burgo A.

J Org Chem. 2011 Nov 18;76(22):9472-7. doi: 10.1021/jo201932m. Epub 2011 Oct 28.

PMID:
21999212
49.

Hetero-Diels-Alder reaction of phosphinyl and phosphonyl nitroso alkenes with conjugated dienes: an aza-Cope rearrangement.

de los Santos JM, Ignacio R, Rubiales G, Aparicio D, Palacios F.

J Org Chem. 2011 Aug 19;76(16):6715-25. doi: 10.1021/jo201116u. Epub 2011 Jul 15.

PMID:
21732627
50.

CCR4 expression in a case of cutaneous Richter's transformation of chronic lymphocytic leukemia (CLL) to diffuse large B-cell lymphoma (DLBCL) and in CLL patients with no skin manifestations.

Nannini PR, Borge M, Mikolaitis VC, Abreu C, Morande PE, Zanetti SR, Oppezzo P, Palacios F, Ledesma I, Bezares RF, Giordano M, Gamberale R.

Eur J Haematol. 2011 Jul;87(1):80-6. doi: 10.1111/j.1600-0609.2011.01613.x.

PMID:
21443542

Supplemental Content

Loading ...
Support Center