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Items: 36

1.
2.

A meningococcal vaccine antigen engineered to increase thermal stability and stabilize protective epitopes.

Konar M, Pajon R, Beernink PT.

Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):14823-8. doi: 10.1073/pnas.1507829112. Epub 2015 Nov 16.

3.

Impaired Immunogenicity of Meningococcal Neisserial Surface Protein A in Human Complement Factor H Transgenic Mice.

Lujan E, Pajon R, Granoff DM.

Infect Immun. 2015 Nov 23;84(2):452-8. doi: 10.1128/IAI.01267-15. Print 2016 Feb.

4.

A Mutant Library Approach to Identify Improved Meningococcal Factor H Binding Protein Vaccine Antigens.

Konar M, Rossi R, Walter H, Pajon R, Beernink PT.

PLoS One. 2015 Jun 9;10(6):e0128185. doi: 10.1371/journal.pone.0128185. eCollection 2015.

5.

A native outer membrane vesicle vaccine confers protection against meningococcal colonization in human CEACAM1 transgenic mice.

Pajon R, Buckwalter CM, Johswich KO, Gray-Owen SD, Granoff DM.

Vaccine. 2015 Mar 10;33(11):1317-1323. doi: 10.1016/j.vaccine.2015.01.057. Epub 2015 Feb 4.

6.

Binding of complement factor H to PorB3 and NspA enhances resistance of Neisseria meningitidis to anti-factor H binding protein bactericidal activity.

Giuntini S, Pajon R, Ram S, Granoff DM.

Infect Immun. 2015 Apr;83(4):1536-45. doi: 10.1128/IAI.02984-14. Epub 2015 Feb 2.

7.

Human factor H (FH) impairs protective meningococcal anti-FHbp antibody responses and the antibodies enhance FH binding.

Costa I, Pajon R, Granoff DM.

MBio. 2014 Aug 26;5(5):e01625-14. doi: 10.1128/mBio.01625-14.

8.

Mutant Native Outer Membrane Vesicles Combined with a Serogroup A Polysaccharide Conjugate Vaccine for Prevention of Meningococcal Epidemics in Africa.

Pajon R, Fergus AM, Granoff DM.

PLoS One. 2013 Jun 21;8(6):e66536. doi: 10.1371/journal.pone.0066536. Print 2013.

9.

Design of meningococcal factor H binding protein mutant vaccines that do not bind human complement factor H.

Pajon R, Beernink PT, Granoff DM.

Infect Immun. 2012 Aug;80(8):2667-77. doi: 10.1128/IAI.00103-12. Epub 2012 May 21. Erratum in: Infect Immun. 2014 Apr;82(4):1742.

10.

The effect of human factor H on immunogenicity of meningococcal native outer membrane vesicle vaccines with over-expressed factor H binding protein.

Beernink PT, Shaughnessy J, Pajon R, Braga EM, Ram S, Granoff DM.

PLoS Pathog. 2012;8(5):e1002688. doi: 10.1371/journal.ppat.1002688. Epub 2012 May 10.

11.

Comparing the similarity of different groups of bacteria to the human proteome.

Trost B, Pajon R, Jayaprakash T, Kusalik A.

PLoS One. 2012;7(4):e34007. doi: 10.1371/journal.pone.0034007. Epub 2012 Apr 25.

12.

A broadly cross-reactive monoclonal antibody against an epitope on the n-terminus of meningococcal fHbp.

Vu DM, Pajon R, Reason DC, Granoff DM.

Sci Rep. 2012;2:341. doi: 10.1038/srep00341. Epub 2012 Mar 28. Erratum in: Sci Rep. 2013 Mar 20;3. doi:10.1038/srep01499.

13.

Bexsero: a multicomponent vaccine for prevention of meningococcal disease.

Gorringe AR, Pajón R.

Hum Vaccin Immunother. 2012 Feb;8(2):174-83. doi: 10.4161/hv.18500. Epub 2012 Feb 1.

PMID:
22426368
14.

Patterns of sequence variation within the Neisseria meningitidis lactoferrin binding proteins.

Adamiak P, Beddek AJ, Pajon R, Schryvers AB.

Biochem Cell Biol. 2012 Jun;90(3):339-50. doi: 10.1139/o11-076. Epub 2012 Mar 7.

PMID:
22397513
15.

Meningococcal factor H binding proteins in epidemic strains from Africa: implications for vaccine development.

Pajon R, Fergus AM, Koeberling O, Caugant DA, Granoff DM.

PLoS Negl Trop Dis. 2011 Sep;5(9):e1302. doi: 10.1371/journal.pntd.0001302. Epub 2011 Sep 6.

16.

Diversity of factor H-binding protein in Neisseria meningitidis carriage isolates.

Marsh JW, Shutt KA, Pajon R, Tulenko MM, Liu S, Hollick RA, Kiehlbauch JA, Clark TA, Stephens DS, Arnold KE, Myers RA, Mayer LW, Harrison LH.

Vaccine. 2011 Aug 11;29(35):6049-58. doi: 10.1016/j.vaccine.2011.06.025. Epub 2011 Jun 24.

17.

Variation in the Neisseria meningitidis FadL-like protein: an evolutionary model for a relatively low-abundance surface antigen.

Yero D, Vipond C, Climent Y, Sardiñas G, Feavers IM, Pajón R.

Microbiology. 2010 Dec;156(Pt 12):3596-608. doi: 10.1099/mic.0.043182-0. Epub 2010 Sep 3. Erratum in: Microbiology. 2011 Feb;157(Pt 2):616.

PMID:
20817647
18.

The genetic structure of Neisseria meningitidis populations in Cuba before and after the introduction of a serogroup BC vaccine.

Climent Y, Urwin R, Yero D, Martinez I, Martín A, Sotolongo F, Maiden MC, Pajón R.

Infect Genet Evol. 2010 May;10(4):546-54. doi: 10.1016/j.meegid.2010.02.002. Epub 2010 Feb 13.

PMID:
20156598
19.

Frequency of factor H-binding protein modular groups and susceptibility to cross-reactive bactericidal activity in invasive meningococcal isolates.

Pajon R, Beernink PT, Harrison LH, Granoff DM.

Vaccine. 2010 Feb 25;28(9):2122-9. doi: 10.1016/j.vaccine.2009.12.027. Epub 2009 Dec 29.

20.

Clonal distribution of disease-associated and healthy carrier isolates of Neisseria meningitidis between 1983 and 2005 in Cuba.

Climent Y, Yero D, Martinez I, Martín A, Jolley KA, Sotolongo F, Maiden MC, Urwin R, Pajón R.

J Clin Microbiol. 2010 Mar;48(3):802-10. doi: 10.1128/JCM.01653-09. Epub 2009 Dec 30.

21.

Identification of new meningococcal serogroup B surface antigens through a systematic analysis of neisserial genomes.

Pajon R, Yero D, Niebla O, Climent Y, Sardiñas G, García D, Perera Y, Llanes A, Delgado M, Cobas K, Caballero E, Taylor S, Brookes C, Gorringe A.

Vaccine. 2009 Dec 11;28(2):532-41. doi: 10.1016/j.vaccine.2009.09.128. Epub 2009 Oct 29.

PMID:
19837092
22.

Assessment of vaccine potential of the Neisseria-specific protein NMB0938.

Sardiñas G, Climent Y, Rodríguez Y, González S, García D, Cobas K, Caballero E, Pérez Y, Brookes C, Taylor S, Gorringe A, Delgado M, Pajón R, Yero D.

Vaccine. 2009 Nov 16;27(49):6910-7. doi: 10.1016/j.vaccine.2009.09.005. Epub 2009 Sep 12.

PMID:
19751688
23.

Proteomic study via a non-gel based approach of meningococcal outer membrane vesicle vaccine obtained from strain CU385: a road map for discovering new antigens.

Gil J, Betancourt LZ, Sardiñas G, Yero D, Niebla O, Delgado M, García D, Pajón R, Sánchez A, González LJ, Padrón G, Campa C, Sotolongo F, Barberó R, Guillén G, Herrera L, Besada V.

Hum Vaccin. 2009 May;5(5):347-56. Epub 2009 May 8.

PMID:
19377283
24.

Lipoprotein NMB0928 from Neisseria meningitidis serogroup B as a novel vaccine candidate.

Delgado M, Yero D, Niebla O, González S, Climent Y, Pérez Y, Cobas K, Caballero E, García D, Pajón R.

Vaccine. 2007 Dec 5;25(50):8420-31. Epub 2007 Oct 11.

PMID:
17996338
25.

On the neisserial vaccine quest: Neisseria Vaccines 2007.

Pajón R, Niebla O, Yero D, Pérez O, Cabrera O, Findlow J, Balmer P, Borrow R.

Expert Rev Anti Infect Ther. 2007 Aug;5(4):545-50. No abstract available.

PMID:
17678419
26.

Neisseria vaccines 2007.

Findlow J, Balmer P, Yero D, Niebla O, Pajón R, Borrow R.

Expert Rev Vaccines. 2007 Aug;6(4):485-9. No abstract available.

PMID:
17669003
27.

Identification by genomic immunization of a pool of DNA vaccine candidates that confer protective immunity in mice against Neisseria meningitidis serogroup B.

Yero D, Pajón R, Pérez Y, Fariñas M, Cobas K, Diaz D, Solis RL, Acosta A, Brookes C, Taylor S, Gorringe A.

Vaccine. 2007 Jul 9;25(28):5175-88. Epub 2007 May 21.

PMID:
17544180
28.

A novel method to screen genomic libraries that combines genomic immunization with the prime-boost strategy.

Yero D, Pajón R, Caballero E, González S, Cobas K, Fariñas M, Lopez Y, Acosta A.

FEMS Immunol Med Microbiol. 2007 Aug;50(3):430-3. Epub 2007 May 30.

29.

Computational identification of beta-barrel outer-membrane proteins in Mycobacterium tuberculosis predicted proteomes as putative vaccine candidates.

Pajón R, Yero D, Lage A, Llanes A, Borroto CJ.

Tuberculosis (Edinb). 2006 May-Jul;86(3-4):290-302. Epub 2006 Mar 20.

PMID:
16542876
30.

Determination of human transferrin concentrations in mouse models of neisserial infection.

Perera Y, Cobas K, Garrido Y, Nazabal C, Brown E, Pajon R.

J Immunol Methods. 2006 Apr 20;311(1-2):153-63. Epub 2006 Feb 28.

PMID:
16529768
31.

Bicistronic expression plasmid for the rapid production of recombinant fused proteins in Escherichia coli.

Yero D, Pajón R, Niebla O, Sardiñas G, Vivar I, Perera Y, García D, Delgado M, Cobas K.

Biotechnol Appl Biochem. 2006 Apr;44(Pt 1):27-34.

PMID:
16396627
32.

Immunization with Neisseria meningitidis outer membrane vesicles prevents bacteremia in neonatal mice.

González S, Caballero E, Soria Y, Cobas K, Granadillo M, Pajón R.

Vaccine. 2006 Mar 6;24(10):1633-43. Epub 2005 Oct 12.

PMID:
16257096
33.

Outer membrane vesicles of Neisseria lactamica as a potential mucosal adjuvant.

Sardiñas G, Reddin K, Pajon R, Gorringe A.

Vaccine. 2006 Jan 12;24(2):206-14. Epub 2005 Aug 8.

PMID:
16115701
34.

SCAPE: a new tool for the Selective CApture of PEptides in protein identification.

Betancourt L, Gil J, Besada V, González LJ, Fernández-de-Cossio J, García L, Pajón R, Sanchez A, Alvarez F, Padrón G.

J Proteome Res. 2005 Mar-Apr;4(2):491-6.

PMID:
15822926
35.

Effect of P64k presensitization on its efficacy as an immunological carrier in mice.

González S, Caballero E, Silva R, Pajón R.

Biochem Biophys Res Commun. 2001 Mar 30;282(2):376-9.

PMID:
11401468
36.

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