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Items: 24

1.

Brain Endothelium: The "Innate Immunity Response Hypothesis" in Cerebral Malaria Pathogenesis.

Pais TF, Penha-Gonçalves C.

Front Immunol. 2019 Jan 29;9:3100. doi: 10.3389/fimmu.2018.03100. eCollection 2018. Review.

2.

Polyphenols journey through blood-brain barrier towards neuronal protection.

Figueira I, Garcia G, Pimpão RC, Terrasso AP, Costa I, Almeida AF, Tavares L, Pais TF, Pinto P, Ventura MR, Filipe A, McDougall GJ, Stewart D, Kim KS, Palmela I, Brites D, Brito MA, Brito C, Santos CN.

Sci Rep. 2017 Sep 13;7(1):11456. doi: 10.1038/s41598-017-11512-6.

3.

Correction: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.

de Oliveira RM, Vicente Miranda H, Francelle L, Pinho R, Szegö ÉM, Martinho R, Munari F, Lázaro DF, Moniot S, Guerreiro P, Fonseca-Ornelas L, Marijanovic Z, Antas P, Gerhardt E, Enguita FJ, Fauvet B, Penque D, Pais TF, Tong Q, Becker S, Kügler S, Lashuel HA, Steegborn C, Zweckstetter M, Outeiro TF.

PLoS Biol. 2017 Apr 5;15(4):e1002601. doi: 10.1371/journal.pbio.1002601. eCollection 2017 Apr.

4.

The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease.

de Oliveira RM, Vicente Miranda H, Francelle L, Pinho R, Szegö ÉM, Martinho R, Munari F, Lázaro DF, Moniot S, Guerreiro P, Fonseca-Ornelas L, Marijanovic Z, Antas P, Gerhardt E, Enguita FJ, Fauvet B, Penque D, Pais TF, Tong Q, Becker S, Kügler S, Lashuel HA, Steegborn C, Zweckstetter M, Outeiro TF.

PLoS Biol. 2017 Mar 3;15(3):e2000374. doi: 10.1371/journal.pbio.2000374. eCollection 2017 Mar. Erratum in: PLoS Biol. 2017 Apr 5;15(4):e1002601.

5.

Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways.

Guerreiro PS, Coelho JE, Sousa-Lima I, Macedo P, Lopes LV, Outeiro TF, Pais TF.

Neuromolecular Med. 2017 Mar;19(1):113-121. doi: 10.1007/s12017-016-8435-5. Epub 2016 Aug 17.

PMID:
27535567
6.

SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models.

Quinti L, Casale M, Moniot S, Pais TF, Van Kanegan MJ, Kaltenbach LS, Pallos J, Lim RG, Naidu SD, Runne H, Meisel L, Rauf NA, Leyfer D, Maxwell MM, Saiah E, Landers JE, Luthi-Carter R, Abagyan R, Dinkova-Kostova AT, Steegborn C, Marsh JL, Lo DC, Thompson LM, Kazantsev AG.

Cell Chem Biol. 2016 Jul 21;23(7):849-861. doi: 10.1016/j.chembiol.2016.05.015. Epub 2016 Jul 14.

7.

Myeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control.

Cardoso F, Castro F, Moreira-Teixeira L, Sousa J, Torrado E, Silvestre R, Castro AG, Saraiva M, Pais TF.

PLoS One. 2015 Jul 2;10(7):e0131904. doi: 10.1371/journal.pone.0131904. eCollection 2015.

8.

Microglia and inflammation: conspiracy, controversy or control?

Fernandes A, Miller-Fleming L, Pais TF.

Cell Mol Life Sci. 2014 Oct;71(20):3969-85. doi: 10.1007/s00018-014-1670-8. Epub 2014 Jul 10. Review.

PMID:
25008043
9.

Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phase.

Miller-Fleming L, Antas P, Pais TF, Smalley JL, Giorgini F, Outeiro TF.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):7012-7. doi: 10.1073/pnas.1319221111. Epub 2014 Apr 2.

10.

The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation.

Pais TF, Szegő ÉM, Marques O, Miller-Fleming L, Antas P, Guerreiro P, de Oliveira RM, Kasapoglu B, Outeiro TF.

EMBO J. 2013 Oct 2;32(19):2603-16. doi: 10.1038/emboj.2013.200. Epub 2013 Sep 6.

11.

Sirtuins: common targets in aging and in neurodegeneration.

de Oliveira RM, Pais TF, Outeiro TF.

Curr Drug Targets. 2010 Oct;11(10):1270-80. Review.

PMID:
20840069
12.

Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway.

Pais TF, Figueiredo C, Peixoto R, Braz MH, Chatterjee S.

J Neuroinflammation. 2008 Oct 9;5:43. doi: 10.1186/1742-2094-5-43.

13.

Neuron-microglia crosstalk up-regulates neuronal FGF-2 expression which mediates neuroprotection against excitotoxicity via JNK1/2.

Figueiredo C, Pais TF, Gomes JR, Chatterjee S.

J Neurochem. 2008 Oct;107(1):73-85. doi: 10.1111/j.1471-4159.2008.05577.x. Epub 2008 Jul 17.

14.

Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation.

Chora AA, Fontoura P, Cunha A, Pais TF, Cardoso S, Ho PP, Lee LY, Sobel RA, Steinman L, Soares MP.

J Clin Invest. 2007 Feb;117(2):438-47. Epub 2007 Jan 25.

15.

Brain macrophage activation in murine cerebral malaria precedes accumulation of leukocytes and CD8+ T cell proliferation.

Pais TF, Chatterjee S.

J Neuroimmunol. 2005 Jun;163(1-2):73-83. Epub 2005 Apr 12.

PMID:
15885309
17.

Blocking the receptor for IL-10 improves antimycobacterial chemotherapy and vaccination.

Silva RA, Pais TF, Appelberg R.

J Immunol. 2001 Aug 1;167(3):1535-41.

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Antigen specificity of T-cell response to Mycobacterium avium infection in mice.

Pais TF, Cunha JF, Appelberg R.

Infect Immun. 2000 Aug;68(8):4805-10.

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Improved clearance of Mycobacterium avium upon disruption of the inducible nitric oxide synthase gene.

Gomes MS, Flórido M, Pais TF, Appelberg R.

J Immunol. 1999 Jun 1;162(11):6734-9.

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