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Mitochondrial DNA somatic mutation burden and heteroplasmy are associated with chronological age, smoking, and HIV infection.

Ziada AS, Lu MY, Ignas-Menzies J, Paintsil E, Li M, Ogbuagu O, Saberi S, Hsieh AYY, Sattha B, Harrigan PR, Kalloger S, Côté HCF; CIHR team grant on cellular aging, HIV comorbidities in women, children (CARMA).

Aging Cell. 2019 Aug 13:e13018. doi: 10.1111/acel.13018. [Epub ahead of print]


Analysis of Haematological Parameters as Predictors of Malaria Infection Using a Logistic Regression Model: A Case Study of a Hospital in the Ashanti Region of Ghana.

Paintsil EK, Omari-Sasu AY, Addo MG, Boateng MA.

Malar Res Treat. 2019 May 21;2019:1486370. doi: 10.1155/2019/1486370. eCollection 2019.


Comparing the Diagnostics Accuracy of CD4+ T-Lymphocyte Count and Percent as a Surrogate Markers of Pediatric HIV Disease.

Ghebremichael M, Michael H, Tubbs J, Paintsil E.

J Math Stat. 2019;15(1):55-64. doi: 10.3844/jmssp.2019.55.64. Epub 2019 Apr 3.


Prevalence and correlates of depression among caregivers of children living with HIV in Ghana: findings from the Sankofa pediatric disclosure study.

Ofori-Atta A, Reynolds NR, Antwi S, Renner L, Nichols JS, Lartey M, Amissah K, Tettey JK, Alhassan A, Ofori IP, Catlin AC, Gan G, Kyriakides TC, Paintsil E; Sankofa Study Team.

AIDS Care. 2019 Mar;31(3):283-292. doi: 10.1080/09540121.2018.1537463. Epub 2018 Oct 25.


Transfer is not a transition - voices of Jamaican adolescents with HIV and their health care providers.

DeSouza F, Paintsil E, Brown T, Pierre R, Keene D, Kim N, Christie C.

AIDS Care. 2019 Mar;31(3):293-297. doi: 10.1080/09540121.2018.1533226. Epub 2018 Oct 20.


High prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana.

Nichols JS, Kyriakides TC, Antwi S, Renner L, Lartey M, Seaneke OA, Obeng R, Catlin AC, Gan G, Reynolds NR, Paintsil E; Sankofa Study Team.

AIDS Care. 2019 Jan;31(1):25-34. doi: 10.1080/09540121.2018.1524113. Epub 2018 Sep 20.


Recovery of Infectious Hepatitis C Virus From Injection Paraphernalia: Implications for Prevention Programs Serving People Who Inject Drugs.

Heimer R, Binka M, Koester S, Grund JC, Patel A, Paintsil E, Lindenbach BD.

J Infect Dis. 2018 Jan 17;217(3):466-473. doi: 10.1093/infdis/jix427.


Upregulation of Apoptosis Pathway Genes in Peripheral Blood Mononuclear Cells of HIV-Infected Individuals with Antiretroviral Therapy-Associated Mitochondrial Toxicity.

Foli Y, Ghebremichael M, Li M, Paintsil E.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00522-17. doi: 10.1128/AAC.00522-17. Print 2017 Aug.


Building Sustainable Local Capacity for Global Health Research in West Africa.

Sam-Agudu NA, Paintsil E, Aliyu MH, Kwara A, Ogunsola F, Afrane YA, Onoka C, Awandare GA, Amponsah G, Cornelius LJ, Mendy G, Sturke R, Ghansah A, Siberry GK, Ezeanolue EE.

Ann Glob Health. 2016 Nov - Dec;82(6):1010-1025. doi: 10.1016/j.aogh.2016.10.011.


Impact of HIV-Status Disclosure on Adherence to Antiretroviral Therapy Among HIV-Infected Children in Resource-Limited Settings: A Systematic Review.

Nichols J, Steinmetz A, Paintsil E.

AIDS Behav. 2017 Jan;21(1):59-69. doi: 10.1007/s10461-016-1481-z. Review.


The DNA Polymerase Gamma R953C Mutant Is Associated with Antiretroviral Therapy-Induced Mitochondrial Toxicity.

Li M, Mislak AC, Foli Y, Agbosu E, Bose V, Bhandari S, Szymanski MR, Shumate CK, Yin YW, Anderson KS, Paintsil E.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5608-11. doi: 10.1128/AAC.00976-16. Print 2016 Sep.


Frequent Episodes of Detectable Viremia in HIV Treatment-Experienced Children is Associated with a Decline in CD4+ T-cells Over Time.

Paintsil E, Martin R, Goldenthal A, Bhandari S, Andiman W, Ghebremichael M.

J AIDS Clin Res. 2016 Apr;7(4). pii: 565. doi: 10.4172/2155-6113.1000565. Epub 2016 Apr 14.


High frequency of mitochondrial DNA mutations in HIV-infected treatment-experienced individuals.

Li M, Foli Y, Liu Z, Wang G, Hu Y, Lu Q, Selvaraj S, Lam W, Paintsil E.

HIV Med. 2017 Jan;18(1):45-55. doi: 10.1111/hiv.12390. Epub 2016 Jun 22.


Viral load monitoring and antiretroviral treatment outcomes in a pediatric HIV cohort in Ghana.

Kukoyi O, Renner L, Powell J, Barry O, Prin M, Kusah J, Cong X, Paintsil E.

BMC Infect Dis. 2016 Feb 3;16:58. doi: 10.1186/s12879-016-1402-9.


Correction: Survival of Hepatitis C Virus in Syringes Is Dependent on the Design of the Syringe-Needle and Dead Space Volume.

Binka M, Paintsil E, Patel A, Lindenbach BD, Heimer R.

PLoS One. 2015 Dec 23;10(12):e0146088. doi: 10.1371/journal.pone.0146088. eCollection 2015. No abstract available.


Sankofa pediatric HIV disclosure intervention cyber data management: building capacity in a resource-limited setting and ensuring data quality.

Catlin AC, Fernando S, Gamage R, Renner L, Antwi S, Tettey JK, Amisah KA, Kyriakides T, Cong X, Reynolds NR, Paintsil E.

AIDS Care. 2015;27 Suppl 1:99-107. doi: 10.1080/09540121.2015.1023246.


HIV knowledge, stigma, and illness beliefs among pediatric caregivers in Ghana who have not disclosed their child's HIV status.

Paintsil E, Renner L, Antwi S, Dame J, Enimil A, Ofori-Atta A, Alhassan A, Ofori IP, Cong X, Kyriakides T, Reynolds NR.

AIDS Care. 2015;27 Suppl 1:18-27. doi: 10.1080/09540121.2015.1007116.


Infectious Diseases of Poverty in Children: A Tale of Two Worlds.

Hansen C, Paintsil E.

Pediatr Clin North Am. 2016 Feb;63(1):37-66. doi: 10.1016/j.pcl.2015.08.002. Review.


Survival of Hepatitis C Virus in Syringes Is Dependent on the Design of the Syringe-Needle and Dead Space Volume.

Binka M, Paintsil E, Patel A, Lindenbach BD, Heimer R.

PLoS One. 2015 Nov 4;10(11):e0139737. doi: 10.1371/journal.pone.0139737. eCollection 2015. Erratum in: PLoS One. 2015;10(12):e0146088.


SANKOFA: a multisite collaboration on paediatric HIV disclosure in Ghana.

Reynolds NR, Ofori-Atta A, Lartey M, Renner L, Antwi S, Enimil A, Catlin AC, Fernando S, Kyriakides TC, Paintsil E.

AIDS. 2015 Jun;29 Suppl 1:S35-45. doi: 10.1097/QAD.0000000000000725.


Disinfection of syringes contaminated with hepatitis C virus by rinsing with household products.

Binka M, Paintsil E, Patel A, Lindenbach BD, Heimer R.

Open Forum Infect Dis. 2015 Feb 23;2(1):ofv017. doi: 10.1093/ofid/ofv017. eCollection 2015 Jan.


Antiretroviral therapy-induced toxicity is associated with increased mRNA expression of telomerase.

Li M, Foli Y, Amakye NY, Klein T, Selvaraj S, Lu L, Paintsil E.

J Clin Pharmacol. 2015 Oct;55(10):1119-24. doi: 10.1002/jcph.520. Epub 2015 May 28. No abstract available.


Cost effectiveness of option B plus for prevention of mother-to-child transmission of HIV in resource-limited countries: evidence from Kumasi, Ghana.

VanDeusen A, Paintsil E, Agyarko-Poku T, Long EF.

BMC Infect Dis. 2015 Mar 18;15:130. doi: 10.1186/s12879-015-0859-2.


Association of circulating cytochrome c with clinical manifestations of antiretroviral-induced toxicity.

Langs-Barlow A, Selvaraj S, Ogbuagu O, Shabanova V, Shapiro ED, Paintsil E.

Mitochondrion. 2015 Jan;20:71-4. doi: 10.1016/j.mito.2014.11.004. Epub 2014 Nov 28.


Two Independent HIV Epidemics in Saint Petersburg, Russia Revealed by Molecular Epidemiology.

Dukhovlinova E, Masharsky A, Toussova O, Verevochkin S, Solovyeva T, Meringof M, Paintsil E, White E, Barbour R, Heimer R, Kozlov A.

AIDS Res Hum Retroviruses. 2015 Jun;31(6):608-14. doi: 10.1089/AID.2014.0150. Epub 2015 Jan 5.


Impact of human immunodeficiency virus type-1 sequence diversity on antiretroviral therapy outcomes.

Langs-Barlow A, Paintsil E.

Viruses. 2014 Oct 20;6(10):3855-72. doi: 10.3390/v6103855. Review.


Antiretroviral therapy-induced mitochondrial toxicity: potential mechanisms beyond polymerase-γ inhibition.

Selvaraj S, Ghebremichael M, Li M, Foli Y, Langs-Barlow A, Ogbuagu A, Barakat L, Tubridy E, Edifor R, Lam W, Cheng YC, Paintsil E.

Clin Pharmacol Ther. 2014 Jul;96(1):110-20. doi: 10.1038/clpt.2014.64. Epub 2014 Mar 17.


Randomized, placebo-controlled single-ascending-dose study to evaluate the safety, tolerability and pharmacokinetics of the HIV nucleoside reverse transcriptase inhibitor, BMS-986001, in healthy subjects.

Urata Y, Paintsil E, Cheng YC, Matsuda T, Sevinsky H, Hawthorne D, Bertz R, Hanna GJ, Grasela D, Hwang C.

J Clin Pharmacol. 2014 Jun;54(6):657-64. doi: 10.1002/jcph.252. Epub 2014 Jan 17.


Hepatitis C virus maintains infectivity for weeks after drying on inanimate surfaces at room temperature: implications for risks of transmission.

Paintsil E, Binka M, Patel A, Lindenbach BD, Heimer R.

J Infect Dis. 2014 Apr 15;209(8):1205-11. doi: 10.1093/infdis/jit648. Epub 2013 Nov 23.


Effectiveness of first-line antiretroviral therapy and correlates of longitudinal changes in CD4 and viral load among HIV-infected children in Ghana.

Barry O, Powell J, Renner L, Bonney EY, Prin M, Ampofo W, Kusah J, Goka B, Sagoe KW, Shabanova V, Paintsil E.

BMC Infect Dis. 2013 Oct 13;13:476. doi: 10.1186/1471-2334-13-476.


Performance of Clinical Criteria for Screening of Possible Antiretroviral Related Mitochondrial Toxicity in HIV-Infected Children in Accra.

Langs-Barlow A, Renner L, Katz K, Northrup V, Paintsil E.

AIDS Res Treat. 2013;2013:249171. doi: 10.1155/2013/249171. Epub 2013 Mar 7.


Virologic and host risk factors for mother-to-child transmission of HIV.

Selvaraj S, Paintsil E.

Curr HIV Res. 2013 Mar;11(2):93-101. Review.


Update on recent guidelines for the management of urinary tract infections in children: the shifting paradigm.

Paintsil E.

Curr Opin Pediatr. 2013 Feb;25(1):88-94. doi: 10.1097/MOP.0b013e32835c14cc. Review.


From the chemistry of epoxy-sugar nucleosides to the discovery of anti-HIV agent 4'-ethynylstavudine-Festinavir.

Haraguchi K, Takeda S, Kubota Y, Kumamoto H, Tanaka H, Hamasaki T, Baba M, Paintsil E, Cheng YC.

Curr Pharm Des. 2013;19(10):1880-97. Review.


Comparison of Disk Diffusion and Etest Methods to Determine the Susceptibility of Staphylococcus aureus Circulating in Riyadh, Saudi Arabia to Fusidic Acid.

Somily AM, Peaper DR, Paintsil E, Murray TS.

Int J Microbiol. 2012;2012:391251. doi: 10.1155/2012/391251. Epub 2012 Jul 24.


Risk Factors and Seroprevalence of Hepatitis C among Patients Hospitalized at Mulago Hospital, Uganda.

O'Reilly JI, Ocama P, Opio CK, Alfred A, Paintsil E, Seremba E, Sofair AN.

J Trop Med. 2011;2011:598341. doi: 10.1155/2011/598341. Epub 2011 Aug 9.


Time to and Predictors of CD4+ T-Lymphocytes Recovery in HIV-Infected Children Initiating Highly Active Antiretroviral Therapy in Ghana.

Renner L, Prin M, Li FY, Goka B, Northrup V, Paintsil E.

AIDS Res Treat. 2011;2011:896040. doi: 10.1155/2011/896040. Epub 2011 May 11.


Analysis of deoxyribonucleotide pools in human cancer cell lines using a liquid chromatography coupled with tandem mass spectrometry technique.

Zhang W, Tan S, Paintsil E, Dutschman GE, Gullen EA, Chu E, Cheng YC.

Biochem Pharmacol. 2011 Aug 15;82(4):411-7. doi: 10.1016/j.bcp.2011.05.009. Epub 2011 May 18.


Monitoring Antiretroviral Therapy in HIV-Infected Children in Resource-Limited Countries: A Tale of Two Epidemics.

Paintsil E.

AIDS Res Treat. 2011;2011:280901. doi: 10.1155/2011/280901. Epub 2010 Dec 2.


Resistance, resistance, go away: persistence of nevirapine-resistant HIV mutations in HIV-infected infants.

Paintsil E.

AIDS. 2011 Apr 24;25(7):997-9. doi: 10.1097/QAD.0b013e3283463d44. No abstract available.


Determinants of individual variation in intracellular accumulation of anti-HIV nucleoside analog metabolites.

Paintsil E, Dutschman GE, Hu R, Grill SP, Wang CJ, Lam W, Li FY, Ghebremichael M, Northrup V, Cheng YC.

Antimicrob Agents Chemother. 2011 Feb;55(2):895-903. doi: 10.1128/AAC.01303-10. Epub 2010 Nov 15.


Survival of hepatitis C virus in syringes: implication for transmission among injection drug users.

Paintsil E, He H, Peters C, Lindenbach BD, Heimer R.

J Infect Dis. 2010 Oct 1;202(7):984-90. doi: 10.1086/656212.


Prevalence and pattern of disclosure of HIV status in HIV-infected children in Ghana.

Kallem S, Renner L, Ghebremichael M, Paintsil E.

AIDS Behav. 2011 Aug;15(6):1121-7. doi: 10.1007/s10461-010-9741-9.


Longitudinal association of alcohol use with HIV disease progression and psychological health of women with HIV.

Ghebremichael M, Paintsil E, Ickovics JR, Vlahov D, Schuman P, Boland R, Schoenbaum E, Moore J, Zhang H.

AIDS Care. 2009 Jul;21(7):834-41. doi: 10.1080/09540120802537864.


Hepatitis C virus infection among drug injectors in St Petersburg, Russia: social and molecular epidemiology of an endemic infection.

Paintsil E, Verevochkin SV, Dukhovlinova E, Niccolai L, Barbour R, White E, Toussova OV, Alexander L, Kozlov AP, Heimer R.

Addiction. 2009 Nov;104(11):1881-90. doi: 10.1111/j.1360-0443.2009.02687.x. Epub 2009 Aug 27.


Association of age at first sex with HIV-1, HSV-2, and other sexual transmitted infections among women in northern Tanzania.

Ghebremichael M, Larsen U, Paintsil E.

Sex Transm Dis. 2009 Sep;36(9):570-6. doi: 10.1097/OLQ.0b013e3181a866b8.


Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile.

Yang G, Paintsil E, Dutschman GE, Grill SP, Wang CJ, Wang J, Tanaka H, Hamasaki T, Baba M, Cheng YC.

Antimicrob Agents Chemother. 2009 Nov;53(11):4640-6. doi: 10.1128/AAC.00686-09. Epub 2009 Aug 24.


High risk behaviors and sexually transmitted infections among men in Tanzania.

Ghebremichael M, Paintsil E.

AIDS Behav. 2011 Jul;15(5):1026-32. doi: 10.1007/s10461-009-9594-2. Epub 2009 Jul 28.

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