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Items: 1 to 50 of 240

1.

Recommended housing densities for research mice: filling the gap in data-driven alternatives.

Svenson KL, Paigen B.

FASEB J. 2018 Dec 6:fj201801972R. doi: 10.1096/fj.201801972R. [Epub ahead of print]

2.

Physician-diagnosed eczema is an independent risk factor for incident mouse skin test sensitization in adults.

Grant T, Dantzer J, Keet C, Peng R, Paigen BJ, Krevans M, Hagberg K, Curtin-Brosnan J, Shreffler W, Matsui EC.

Allergy Asthma Proc. 2018 Jul 1;39(4):311-315. doi: 10.2500/aap.2018.39.4137.

3.

Atopy as a Modifier of the Relationships Between Endotoxin Exposure and Symptoms Among Laboratory Animal Workers.

Newton AN, Davis M, Koehler K, Shreffler W, Ahluwalia S, Metwali N, Thorne PS, Paigen BJ, Matsui EC.

Ann Work Expo Health. 2017 Oct 1;61(8):1024-1028. doi: 10.1093/annweh/wxx061.

4.

Effects of Varied Housing Density on a Hybrid Mouse Strain Followed for 20 Months.

Paigen B, Currer JM, Svenson KL.

PLoS One. 2016 Feb 22;11(2):e0149647. doi: 10.1371/journal.pone.0149647. eCollection 2016.

5.

Integrative Mouse and Human Studies Implicate ANGPT1 and ZBTB7C as Susceptibility Genes to Ischemic Injury.

Du R, Zhou J, Lorenzano S, Liu W, Charoenvimolphan N, Qian B, Xu J, Wang J, Zhang X, Wang X, Berndt A, Devan WJ, Valant VJ, Wang J, Furie KL, Rosand J, Rost N, Friedlander RM, Paigen B, Weiss ST.

Stroke. 2015 Dec;46(12):3514-22. doi: 10.1161/STROKEAHA.115.010767. Epub 2015 Nov 5.

6.

Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span.

Bogue MA, Peters LL, Paigen B, Korstanje R, Yuan R, Ackert-Bicknell C, Grubb SC, Churchill GA, Chesler EJ.

J Gerontol A Biol Sci Med Sci. 2016 Feb;71(2):170-7. doi: 10.1093/gerona/glu223. Epub 2014 Dec 22.

7.

Genetic Regulation of Female Sexual Maturation and Longevity Through Circulating IGF1.

Yuan R, Gatti DM, Krier R, Malay E, Schultz D, Peters LL, Churchill GA, Harrison DE, Paigen B.

J Gerontol A Biol Sci Med Sci. 2015 Jul;70(7):817-26. doi: 10.1093/gerona/glu114. Epub 2014 Jul 28.

8.

Effects of housing density in five inbred strains of mice.

Morgan JL, Svenson KL, Lake JP, Zhang W, Stearns TM, Marion MA, Peters LL, Paigen B, Donahue LR.

PLoS One. 2014 Mar 21;9(3):e90012. doi: 10.1371/journal.pone.0090012. eCollection 2014.

9.

The effect of culling on health and physiology of mouse litters.

Paigen B, Marion MA, Stearns TM, Harper JM, Svenson KL.

Lab Anim. 2014 Jul;48(3):207-215. Epub 2014 Feb 14.

10.

Modeling hepatic osteodystrophy in Abcb4 deficient mice.

Hochrath K, Ehnert S, Ackert-Bicknell CL, Lau Y, Schmid A, Krawczyk M, Hengstler JG, Dunn J, Hiththetiya K, Rathkolb B, Micklich K, Hans W, Fuchs H, Gailus-Durner V, Wolf E, de Angelis MH, Dooley S, Paigen B, Wildemann B, Lammert F, Nüssler AK.

Bone. 2013 Aug;55(2):501-11. doi: 10.1016/j.bone.2013.03.012. Epub 2013 Mar 29.

11.

Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.

Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST.

PLoS One. 2013;8(2):e56179. doi: 10.1371/journal.pone.0056179. Epub 2013 Feb 14.

12.

Recalculation of 23 mouse HDL QTL datasets improves accuracy and allows for better candidate gene analysis.

Ackert-Bicknell C, Paigen B, Korstanje R.

J Lipid Res. 2013 Apr;54(4):984-94. doi: 10.1194/jlr.M033035. Epub 2013 Feb 7.

13.

Early gene expression differences in inbred mouse strains with susceptibility to pulmonary adenomas.

Stearns TM, Cario CL, Savage HS, Sundberg JP, Paigen B, Berndt A.

Exp Mol Pathol. 2012 Dec;93(3):455-61. doi: 10.1016/j.yexmp.2012.09.015. Epub 2012 Sep 28.

PMID:
23026400
14.

A major X-linked locus affects kidney function in mice.

Leduc MS, Savage HS, Stearns TM, Cario CL, Walsh KA, Paigen B, Berndt A.

Mol Genet Genomics. 2012 Dec;287(11-12):845-54. doi: 10.1007/s00438-012-0720-x. Epub 2012 Sep 26.

15.

Physiological effects of housing density on C57BL/6J mice over a 9-month period.

Paigen B, Svenson KL, Von Smith R, Marion MA, Stearns T, Peters LL, Smith AL.

J Anim Sci. 2012 Dec;90(13):5182-92. doi: 10.2527/jas.2012-5417. Epub 2012 Sep 5.

16.

Genetic analysis of albuminuria in collaborative cross and multiple mouse intercross populations.

Thaisz J, Tsaih SW, Feng M, Philip VM, Zhang Y, Yanas L, Sheehan S, Xu L, Miller DR, Paigen B, Chesler EJ, Churchill GA, Dipetrillo K.

Am J Physiol Renal Physiol. 2012 Oct;303(7):F972-81. doi: 10.1152/ajprenal.00690.2011. Epub 2012 Aug 1.

17.

Differences in health status affect susceptibility and mapping of genetic loci for atherosclerosis (fatty streak) in inbred mice.

Srivastava U, Paigen BJ, Korstanje R.

Arterioscler Thromb Vasc Biol. 2012 Oct;32(10):2380-6. doi: 10.1161/ATVBAHA.112.255703. Epub 2012 Jul 26.

18.

Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains.

Yuan R, Meng Q, Nautiyal J, Flurkey K, Tsaih SW, Krier R, Parker MG, Harrison DE, Paigen B.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8224-9. doi: 10.1073/pnas.1121113109. Epub 2012 May 7.

19.

Using bioinformatics and systems genetics to dissect HDL-cholesterol genetics in an MRL/MpJ x SM/J intercross.

Leduc MS, Blair RH, Verdugo RA, Tsaih SW, Walsh K, Churchill GA, Paigen B.

J Lipid Res. 2012 Jun;53(6):1163-75. doi: 10.1194/jlr.M025833. Epub 2012 Apr 11.

20.

Genetic variation in TRPS1 may regulate hip geometry as well as bone mineral density.

Ackert-Bicknell CL, Demissie S, Tsaih SW, Beamer WG, Cupples LA, Paigen BJ, Hsu YH, Kiel DP, Karasik D.

Bone. 2012 May;50(5):1188-95. doi: 10.1016/j.bone.2012.01.011. Epub 2012 Jan 28.

21.

Genetic analysis of lung function in inbred mice suggests vitamin D receptor as a candidate gene.

Berndt A, Savage HS, Stearns TM, Paigen B.

Mol Genet Genomics. 2011 Oct;286(3-4):237-46. doi: 10.1007/s00438-011-0642-z. Epub 2011 Aug 19.

22.

Identification of fat4 and tsc22d1 as novel candidate genes for spontaneous pulmonary adenomas.

Berndt A, Cario CL, Silva KA, Kennedy VE, Harrison DE, Paigen B, Sundberg JP.

Cancer Res. 2011 Sep 1;71(17):5779-91. doi: 10.1158/0008-5472.CAN-11-1418. Epub 2011 Jul 15.

23.

Both the variability and level of mouse allergen exposure influence the phenotype of the immune response in workers at a mouse facility.

Peng RD, Paigen B, Eggleston PA, Hagberg KA, Krevans M, Curtin-Brosnan J, Benson C, Shreffler WG, Matsui EC.

J Allergy Clin Immunol. 2011 Aug;128(2):390-396.e7. doi: 10.1016/j.jaci.2011.04.050. Epub 2011 Jun 22.

24.

Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice.

Leduc MS, Hageman RS, Verdugo RA, Tsaih SW, Walsh K, Churchill GA, Paigen B.

J Lipid Res. 2011 Sep;52(9):1672-82. doi: 10.1194/jlr.M011130. Epub 2011 May 26.

25.

The mouse QTL map helps interpret human genome-wide association studies for HDL cholesterol.

Leduc MS, Lyons M, Darvishi K, Walsh K, Sheehan S, Amend S, Cox A, Orho-Melander M, Kathiresan S, Paigen B, Korstanje R.

J Lipid Res. 2011 Jun;52(6):1139-49. doi: 10.1194/jlr.M009175. Epub 2011 Mar 28.

26.

Mice as a mammalian model for research on the genetics of aging.

Yuan R, Peters LL, Paigen B.

ILAR J. 2011;52(1):4-15. Review.

27.

A Bayesian framework for inference of the genotype-phenotype map for segregating populations.

Hageman RS, Leduc MS, Korstanje R, Paigen B, Churchill GA.

Genetics. 2011 Apr;187(4):1163-70. doi: 10.1534/genetics.110.123273. Epub 2011 Jan 17.

28.

The mouse as a model for understanding chronic diseases of aging: the histopathologic basis of aging in inbred mice.

Sundberg JP, Berndt A, Sundberg BA, Silva KA, Kennedy V, Bronson R, Yuan R, Paigen B, Harrison D, Schofield PN.

Pathobiol Aging Age Relat Dis. 2011;1. doi: 10.3402/pba.v1i0.7179. Epub 2011 Jun 1.

29.

Occupational mouse allergen exposure among non-mouse handlers.

Curtin-Brosnan J, Paigen B, Hagberg KA, Langley S, O'Neil EA, Krevans M, Eggleston PA, Matsui EC.

J Occup Environ Hyg. 2010 Dec;7(12):726-34. doi: 10.1080/15459624.2010.530906.

30.

Sequence variation at multiple loci influences red cell hemoglobin concentration.

Peters LL, Shavit JA, Lambert AJ, Tsaih SW, Li Q, Su Z, Leduc MS, Paigen B, Churchill GA, Ginsburg D, Brugnara C.

Blood. 2010 Dec 16;116(25):e139-49. doi: 10.1182/blood-2010-05-283879. Epub 2010 Sep 10.

31.

Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice.

Berndt A, Leme AS, Williams LK, Von Smith R, Savage HS, Stearns TM, Tsaih SW, Shapiro SD, Peters LL, Paigen B, Svenson KL.

Physiol Genomics. 2011 Jan 7;43(1):1-11. doi: 10.1152/physiolgenomics.00108.2010. Epub 2010 Sep 7.

32.

Identification of genetic determinants of IGF-1 levels and longevity among mouse inbred strains.

Leduc MS, Hageman RS, Meng Q, Verdugo RA, Tsaih SW, Churchill GA, Paigen B, Yuan R.

Aging Cell. 2010 Oct;9(5):823-36. doi: 10.1111/j.1474-9726.2010.00612.x.

33.

Untangling HDL quantitative trait loci on mouse chromosome 5 and identifying Scarb1 and Acads as the underlying genes.

Su Z, Leduc MS, Korstanje R, Paigen B.

J Lipid Res. 2010 Sep;51(9):2706-13. doi: 10.1194/jlr.M008110. Epub 2010 Jun 19.

34.

Combining QTL data for HDL cholesterol levels from two different species leads to smaller confidence intervals.

Cox A, Sheehan SM, Klöting I, Paigen B, Korstanje R.

Heredity (Edinb). 2010 Nov;105(5):426-32. doi: 10.1038/hdy.2010.75. Epub 2010 Jun 16.

35.

Congenic and bioinformatics analyses resolved a major-effect Fob3b QTL on mouse Chr 15 into two closely linked loci.

Prevorsek Z, Gorjanc G, Paigen B, Horvat S.

Mamm Genome. 2010 Apr;21(3-4):172-85. doi: 10.1007/s00335-010-9252-z. Epub 2010 Mar 5.

PMID:
20204375
36.

Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map.

Ackert-Bicknell CL, Karasik D, Li Q, Smith RV, Hsu YH, Churchill GA, Paigen BJ, Tsaih SW.

J Bone Miner Res. 2010 Aug;25(8):1808-20. doi: 10.1002/jbmr.72.

37.

A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci.

Leme AS, Berndt A, Williams LK, Tsaih SW, Szatkiewicz JP, Verdugo R, Paigen B, Shapiro SD.

Mol Genet Genomics. 2010 Apr;283(4):317-26. doi: 10.1007/s00438-010-0515-x. Epub 2010 Feb 9.

38.

An experimental assessment of in silico haplotype association mapping in laboratory mice.

Burgess-Herbert SL, Tsaih SW, Stylianou IM, Walsh K, Cox AJ, Paigen B.

BMC Genet. 2009 Dec 9;10:81. doi: 10.1186/1471-2156-10-81.

39.

Effects of atherogenic diet on hepatic gene expression across mouse strains.

Shockley KR, Witmer D, Burgess-Herbert SL, Paigen B, Churchill GA.

Physiol Genomics. 2009 Nov 6;39(3):172-82. doi: 10.1152/physiolgenomics.90350.2008. Epub 2009 Aug 11.

40.

A customized and versatile high-density genotyping array for the mouse.

Yang H, Ding Y, Hutchins LN, Szatkiewicz J, Bell TA, Paigen BJ, Graber JH, de Villena FP, Churchill GA.

Nat Methods. 2009 Sep;6(9):663-6. doi: 10.1038/nmeth.1359. Epub 2009 Aug 9.

41.

Novel ENU-induced point mutation in scavenger receptor class B, member 1, results in liver specific loss of SCARB1 protein.

Stylianou IM, Svenson KL, VanOrman SK, Langle Y, Millar JS, Paigen B, Rader DJ.

PLoS One. 2009 Aug 5;4(8):e6521. doi: 10.1371/journal.pone.0006521.

42.

Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels.

Yuan R, Tsaih SW, Petkova SB, Marin de Evsikova C, Xing S, Marion MA, Bogue MA, Mills KD, Peters LL, Bult CJ, Rosen CJ, Sundberg JP, Harrison DE, Churchill GA, Paigen B.

Aging Cell. 2009 Jun;8(3):277-87. doi: 10.1111/j.1474-9726.2009.00478.x. Epub 2009 Apr 9.

43.

A new standard genetic map for the laboratory mouse.

Cox A, Ackert-Bicknell CL, Dumont BL, Ding Y, Bell JT, Brockmann GA, Wergedal JE, Bult C, Paigen B, Flint J, Tsaih SW, Churchill GA, Broman KW.

Genetics. 2009 Aug;182(4):1335-44. doi: 10.1534/genetics.109.105486. Epub 2009 Jun 17.

44.

Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene.

Su Z, Ishimori N, Chen Y, Leiter EH, Churchill GA, Paigen B, Stylianou IM.

J Lipid Res. 2009 Oct;50(10):2083-94. doi: 10.1194/jlr.M900076-JLR200. Epub 2009 May 12.

45.

Genetic influence on electrocardiogram time intervals and heart rate in aging mice.

Xing S, Tsaih SW, Yuan R, Svenson KL, Jorgenson LM, So M, Paigen BJ, Korstanje R.

Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1907-13. doi: 10.1152/ajpheart.00681.2008. Epub 2009 Apr 24.

46.

Farp2 and Stk25 are candidate genes for the HDL cholesterol locus on mouse chromosome 1.

Su Z, Cox A, Shen Y, Stylianou IM, Paigen B.

Arterioscler Thromb Vasc Biol. 2009 Jan;29(1):107-13. doi: 10.1161/ATVBAHA.108.178384. Epub 2008 Nov 6.

47.

Practical applications of the bioinformatics toolbox for narrowing quantitative trait loci.

Burgess-Herbert SL, Cox A, Tsaih SW, Paigen B.

Genetics. 2008 Dec;180(4):2227-35. doi: 10.1534/genetics.108.090175. Epub 2008 Oct 9.

48.

Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects.

Korstanje R, Desai J, Lazar G, King B, Rollins J, Spurr M, Joseph J, Kadambi S, Li Y, Cherry A, Matteson PG, Paigen B, Millonig JH.

Physiol Genomics. 2008 Nov 12;35(3):296-304. doi: 10.1152/physiolgenomics.90260.2008. Epub 2008 Sep 16.

PMID:
18796533
49.

Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: importance of testing candidate genes in targeted mutant mice.

Su Z, Wang X, Tsaih SW, Zhang A, Cox A, Sheehan S, Paigen B.

J Lipid Res. 2009 Jan;50(1):116-25. doi: 10.1194/jlr.M800411-JLR200. Epub 2008 Sep 4.

50.

PPARG by dietary fat interaction influences bone mass in mice and humans.

Ackert-Bicknell CL, Demissie S, Marín de Evsikova C, Hsu YH, DeMambro VE, Karasik D, Cupples LA, Ordovas JM, Tucker KL, Cho K, Canalis E, Paigen B, Churchill GA, Forejt J, Beamer WG, Ferrari S, Bouxsein ML, Kiel DP, Rosen CJ.

J Bone Miner Res. 2008 Sep;23(9):1398-408. doi: 10.1359/jbmr.080419.

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