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Items: 1 to 50 of 144

1.

c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells.

Shikatani EA, Besla R, Ensan S, Upadhye A, Khyzha N, Li A, Emoto T, Chiu F, Degousee N, Moreau JM, Perry HM, Thayaparan D, Cheng HS, Pacheco S, Smyth D, Noyan H, Zavitz CCJ, Bauer CMT, Hilgendorf I, Libby P, Swirski FK, Gommerman JL, Fish JE, Stampfli MR, Cybulsky MI, Rubin BB, Paige CJ, Bender TP, McNamara CA, Husain M, Robbins CS.

Cell Rep. 2019 May 21;27(8):2304-2312.e6. doi: 10.1016/j.celrep.2019.04.090.

2.

Differential regulation of IgA+ B cells in vitro by stromal cells from distinctive anatomical compartments.

Cen SY, Moreau JM, Furlonger C, Berger A, Paige CJ.

J Leukoc Biol. 2019 Mar;105(3):507-518. doi: 10.1002/JLB.1A0517-172RR. Epub 2018 Dec 21.

PMID:
30576006
3.

Functional Consequences of the Postnatal Switch From Neonatal to Mutant Adult Glycine Receptor α1 Subunits in the Shaky Mouse Model of Startle Disease.

Schaefer N, Zheng F, van Brederode J, Berger A, Leacock S, Hirata H, Paige CJ, Harvey RJ, Alzheimer C, Villmann C.

Front Mol Neurosci. 2018 May 24;11:167. doi: 10.3389/fnmol.2018.00167. eCollection 2018.

4.

Cytokines and depression in cancer patients and caregivers.

Li M, Kouzmina E, McCusker M, Rodin D, Boutros PC, Paige CJ, Rodin G.

Neuropsychiatr Dis Treat. 2017 Nov 28;13:2903-2911. doi: 10.2147/NDT.S144774. eCollection 2017.

5.

Bone marrow basophils provide survival signals to immature B cells in vitro but are dispensable in vivo.

Moreau JM, Cen S, Berger A, Furlonger C, Paige CJ.

PLoS One. 2017 Sep 28;12(9):e0185509. doi: 10.1371/journal.pone.0185509. eCollection 2017.

6.

Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease.

Schaefer N, Berger A, van Brederode J, Zheng F, Zhang Y, Leacock S, Littau L, Jablonka S, Malhotra S, Topf M, Winter F, Davydova D, Lynch JW, Paige CJ, Alzheimer C, Harvey RJ, Villmann C.

J Neurosci. 2017 Aug 16;37(33):7948-7961. doi: 10.1523/JNEUROSCI.0009-17.2017. Epub 2017 Jul 19.

7.

Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML.

Huang J, Liu Y, Au BC, Barber DL, Arruda A, Schambach A, Rothe M, Minden MD, Paige CJ, Medin JA.

Mol Ther Methods Clin Dev. 2016 Dec 7;3:16074. eCollection 2016.

8.

Pro- and anti-inflammatory cytokine associations with major depression in cancer patients.

Li M, Kouzmina E, McCusker M, Rodin D, Boutros PC, Paige CJ, Rodin G.

Psychooncology. 2017 Dec;26(12):2149-2156. doi: 10.1002/pon.4316. Epub 2016 Dec 6.

PMID:
27862626
9.

Hemokinin-1 mediates anxiolytic and anti-depressant-like actions in mice.

Borbély É, Hajna Z, Nabi L, Scheich B, Tékus V, László K, Ollmann T, Kormos V, Gaszner B, Karádi Z, Lénárd L, Paige CJ, Quinn JP, Szolcsányi J, Pintér E, Keeble J, Berger A, Helyes Z.

Brain Behav Immun. 2017 Jan;59:219-232. doi: 10.1016/j.bbi.2016.09.004. Epub 2016 Sep 9.

PMID:
27621226
10.

Tumor-secreted products repress B-cell lymphopoiesis in a murine model of breast cancer.

Moreau JM, Mielnik M, Berger A, Furlonger C, Paige CJ.

Eur J Immunol. 2016 Dec;46(12):2835-2841. doi: 10.1002/eji.201646552. Epub 2016 Oct 4.

11.

Inflammation rapidly reorganizes mouse bone marrow B cells and their environment in conjunction with early IgM responses.

Moreau JM, Berger A, Nelles ME, Mielnik M, Furlonger C, Cen SY, Besla R, Robbins CS, Paige CJ.

Blood. 2015 Sep 3;126(10):1184-92. doi: 10.1182/blood-2015-03-635805. Epub 2015 Jul 13.

PMID:
26170030
12.

CD4+ T cell plasticity engenders robust immunity in response to cytokine therapy.

Nelles ME, Paige CJ.

Oncoimmunology. 2015 Jan 22;4(3):e994370. eCollection 2015 Mar.

13.

Markedly perturbed hematopoiesis in acid ceramidase deficient mice.

Dworski S, Berger A, Furlonger C, Moreau JM, Yoshimitsu M, Trentadue J, Au BC, Paige CJ, Medin JA.

Haematologica. 2015 May;100(5):e162-5. doi: 10.3324/haematol.2014.108530. Epub 2015 Feb 14. No abstract available.

14.

Hemokinin-1 is an important mediator of endotoxin-induced acute airway inflammation in the mouse.

Hajna Z, Borbély É, Kemény Á, Botz B, Kereskai L, Szolcsányi J, Pintér E, Paige CJ, Berger A, Helyes Z.

Peptides. 2015 Feb;64:1-7. doi: 10.1016/j.peptides.2014.12.002. Epub 2014 Dec 22.

PMID:
25541043
15.

Murine splenic CD4⁺ T cells, induced by innate immune cell interactions and secreted factors, develop antileukemia cytotoxicity.

Nelles ME, Moreau JM, Furlonger CL, Berger A, Medin JA, Paige CJ.

Cancer Immunol Res. 2014 Nov;2(11):1113-24. doi: 10.1158/2326-6066.CIR-13-0208. Epub 2014 Aug 25.

16.

Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex.

Wang L, Opland D, Tsai S, Luk CT, Schroer SA, Allison MB, Elia AJ, Furlonger C, Suzuki A, Paige CJ, Mak TW, Winer DA, Myers MG Jr, Woo M.

Nat Med. 2014 May;20(5):484-92. doi: 10.1038/nm.3527. Epub 2014 Apr 20.

PMID:
24747746
17.

Developing and implementing a fluoride varnish programme for young children in Bradford, UK.

Paige CJ, Shahid SK.

Community Dent Health. 2014 Mar;31(1):5-8. No abstract available.

PMID:
24741886
18.

Role of neurokinin 1 receptors in dextran sulfate-induced colitis: studies with gene-deleted mice and the selective receptor antagonist netupitant.

Szitter I, Pintér E, Perkecz A, Kemény A, Kun J, Kereskai L, Pietra C, Quinn JP, Zimmer A, Berger A, Paige CJ, Helyes Z.

Inflamm Res. 2014 May;63(5):399-409. doi: 10.1007/s00011-014-0712-x. Epub 2014 Jan 28.

PMID:
24468892
19.

Localized interleukin-12 delivery for immunotherapy of solid tumours.

Wei LZ, Xu Y, Nelles EM, Furlonger C, Wang JC, Di Grappa MA, Khokha R, Medin JA, Paige CJ.

J Cell Mol Med. 2013 Nov;17(11):1465-74. doi: 10.1111/jcmm.12121. Epub 2013 Nov 19.

20.

GATA-3 regulates the self-renewal of long-term hematopoietic stem cells.

Frelin C, Herrington R, Janmohamed S, Barbara M, Tran G, Paige CJ, Benveniste P, Zuñiga-Pflücker JC, Souabni A, Busslinger M, Iscove NN.

Nat Immunol. 2013 Oct;14(10):1037-44. doi: 10.1038/ni.2692. Epub 2013 Aug 25.

21.

Neurokinin-1 receptor signalling impacts bone marrow repopulation efficiency.

Berger A, Frelin C, Shah DK, Benveniste P, Herrington R, Gerard NP, Zúñiga-Pflücker JC, Iscove NN, Paige CJ.

PLoS One. 2013;8(3):e58787. doi: 10.1371/journal.pone.0058787. Epub 2013 Mar 14.

22.

Homeodomain-interacting protein kinase (HIPK)-1 is required for splenic B cell homeostasis and optimal T-independent type 2 humoral response.

Guerra FM, Gommerman JL, Corfe SA, Paige CJ, Rottapel R.

PLoS One. 2012;7(4):e35533. doi: 10.1371/journal.pone.0035533. Epub 2012 Apr 24.

23.

Diminished pheromone-induced sexual behavior in neurokinin-1 receptor deficient (TACR1(-/-)) mice.

Berger A, Tran AH, Dida J, Minkin S, Gerard NP, Yeomans J, Paige CJ.

Genes Brain Behav. 2012 Jul;11(5):568-76. doi: 10.1111/j.1601-183X.2012.00787.x. Epub 2012 Apr 26.

24.

The many roles of IL-7 in B cell development; mediator of survival, proliferation and differentiation.

Corfe SA, Paige CJ.

Semin Immunol. 2012 Jun;24(3):198-208. doi: 10.1016/j.smim.2012.02.001. Epub 2012 Mar 14. Review.

PMID:
22421572
25.

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut.

Fritz JH, Rojas OL, Simard N, McCarthy DD, Hapfelmeier S, Rubino S, Robertson SJ, Larijani M, Gosselin J, Ivanov II, Martin A, Casellas R, Philpott DJ, Girardin SE, McCoy KD, Macpherson AJ, Paige CJ, Gommerman JL.

Nature. 2011 Dec 11;481(7380):199-203. doi: 10.1038/nature10698.

26.

Seasonal H1N1 influenza virus infection induces cross-protective pandemic H1N1 virus immunity through a CD8-independent, B cell-dependent mechanism.

Fang Y, Banner D, Kelvin AA, Huang SS, Paige CJ, Corfe SA, Kane KP, Bleackley RC, Rowe T, Leon AJ, Kelvin DJ.

J Virol. 2012 Feb;86(4):2229-38. doi: 10.1128/JVI.05540-11. Epub 2011 Nov 30.

27.

Modulation of IL-7 thresholds by SOCS proteins in developing B lineage cells.

Corfe SA, Rottapel R, Paige CJ.

J Immunol. 2011 Oct 1;187(7):3499-510. doi: 10.4049/jimmunol.1100424. Epub 2011 Aug 26.

28.

Analysis of the role of IL-21 in development of murine B cell progenitors in the bone marrow.

Simard N, Konforte D, Tran AH, Esufali J, Leonard WJ, Paige CJ.

J Immunol. 2011 May 1;186(9):5244-53. doi: 10.4049/jimmunol.1004040. Epub 2011 Mar 23.

29.

Novel interactions of fluorinated nucleotide derivatives targeting orotidine 5'-monophosphate decarboxylase.

Lewis M, Meza-Avina ME, Wei L, Crandall IE, Bello AM, Poduch E, Liu Y, Paige CJ, Kain KC, Pai EF, Kotra LP.

J Med Chem. 2011 Apr 28;54(8):2891-901. doi: 10.1021/jm101642g. Epub 2011 Mar 21.

30.

Early B-cell factor regulates the expression of Hemokinin-1 in the olfactory epithelium and differentiating B lymphocytes.

Tran AH, Berger A, Wu GE, Kee BL, Paige CJ.

J Neuroimmunol. 2011 Mar;232(1-2):41-50. doi: 10.1016/j.jneuroim.2010.09.027. Epub 2010 Oct 20.

PMID:
20965576
31.

Targeted deletion of the tachykinin 4 gene (TAC4-/-) influences the early stages of B lymphocyte development.

Berger A, Benveniste P, Corfe SA, Tran AH, Barbara M, Wakeham A, Mak TW, Iscove NN, Paige CJ.

Blood. 2010 Nov 11;116(19):3792-801. doi: 10.1182/blood-2010-06-291062. Epub 2010 Jul 26.

PMID:
20660792
32.

Antimicrobial properties of hemokinin-1 against strains of Pseudomonas aeruginosa.

Berger A, Tran AH, Dedier H, Gardam MA, Paige CJ.

Life Sci. 2009 Nov 4;85(19-20):700-3. doi: 10.1016/j.lfs.2009.09.011. Epub 2009 Oct 2.

PMID:
19800893
33.

Interleukin-21 regulates expression of the immediate-early lytic cycle genes and proteins in Epstein-Barr Virus infected B cells.

Konforte D, Paige CJ.

Virus Res. 2009 Sep;144(1-2):339-43. doi: 10.1016/j.virusres.2009.05.003. Epub 2009 May 15.

PMID:
19447148
34.

Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents.

Bello AM, Konforte D, Poduch E, Furlonger C, Wei L, Liu Y, Lewis M, Pai EF, Paige CJ, Kotra LP.

J Med Chem. 2009 Mar 26;52(6):1648-58. doi: 10.1021/jm801224t.

PMID:
19260677
35.

IL-21: an executor of B cell fate.

Konforte D, Simard N, Paige CJ.

J Immunol. 2009 Feb 15;182(4):1781-7. doi: 10.4049/jimmunol.0803009. Review.

36.

Regulatory mechanisms in the differential expression of Hemokinin-1.

Tran AH, Berger A, Wu GE, Paige CJ.

Neuropeptides. 2009 Feb;43(1):1-12. doi: 10.1016/j.npep.2008.10.002. Epub 2008 Dec 9.

PMID:
19081134
37.

IL-12 immunotherapy of murine leukaemia: comparison of systemic versus gene modified cell therapy.

Labbe A, Nelles M, Walia J, Jia L, Furlonger C, Nonaka T, Medin JA, Paige CJ.

J Cell Mol Med. 2009 Aug;13(8B):1962-76. doi: 10.1111/j.1582-4934.2008.00412.x.

38.

Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3.

Janzen V, Fleming HE, Riedt T, Karlsson G, Riese MJ, Lo Celso C, Reynolds G, Milne CD, Paige CJ, Karlsson S, Woo M, Scadden DT.

Cell Stem Cell. 2008 Jun 5;2(6):584-94. doi: 10.1016/j.stem.2008.03.012.

39.
40.

Interleukin-21 regulates expression of key Epstein-Barr virus oncoproteins, EBNA2 and LMP1, in infected human B cells.

Konforte D, Simard N, Paige CJ.

Virology. 2008 Apr 25;374(1):100-13. doi: 10.1016/j.virol.2007.12.027. Epub 2008 Jan 28.

41.

The future of health research is hanging in the balance.

Paige CJ.

CMAJ. 2007 Oct 23;177(9):1057-8. No abstract available.

42.

Generation and characterization of stromal cell independent IL-7 dependent B cell lines.

Corfe SA, Gray AP, Paige CJ.

J Immunol Methods. 2007 Aug 31;325(1-2):9-19. Epub 2007 Jun 12.

PMID:
17599344
43.
44.
45.

Tachykinins in the immune system.

Zhang Y, Berger A, Milne CD, Paige CJ.

Curr Drug Targets. 2006 Aug;7(8):1011-20. Review.

PMID:
16918329
46.

Murine model of immune-mediated rejection of the acute lymphoblastic leukemia 70Z/3.

Labbe A, Tran AH, Paige CJ.

J Immunol. 2006 May 1;176(9):5354-61.

47.

IL-7: a key regulator of B lymphopoiesis.

Milne CD, Paige CJ.

Semin Immunol. 2006 Feb;18(1):20-30. Epub 2005 Nov 21. Review.

PMID:
16303314
48.

Stromal cells attract B-cell progenitors to promote B-cell-B-cell contact and maturation.

Milne CD, Zhang Y, Paige CJ.

Scand J Immunol. 2005 Jul;62 Suppl 1:67-72.

49.
50.

IL-7 does not prevent pro-B/pre-B cell maturation to the immature/sIgM(+) stage.

Milne CD, Fleming HE, Paige CJ.

Eur J Immunol. 2004 Oct;34(10):2647-55.

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