Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 60


Cannabinoid Attenuation of Intestinal Inflammation in Chronic SIV-Infected Rhesus Macaques Involves T Cell Modulation and Differential Expression of Micro-RNAs and Pro-inflammatory Genes.

Kumar V, Torben W, Mansfield J, Alvarez X, Vande Stouwe C, Li J, Byrareddy SN, Didier PJ, Pahar B, Molina PE, Mohan M.

Front Immunol. 2019 Apr 30;10:914. doi: 10.3389/fimmu.2019.00914. eCollection 2019.


Immunological Responses to the Relapsing Fever Spirochete Borrelia turicatae in Infected Rhesus Macaques: Implications for Pathogenesis and Diagnosis.

Embers ME, Krishnavajhala A, Armstrong BA, Curtis MW, Pahar B, Wilder HK, Allen MS, Beare PA, Hasenkampf NR, Lopez JE.

Infect Immun. 2019 Mar 25;87(4). pii: e00900-18. doi: 10.1128/IAI.00900-18. Print 2019 Apr.


Lack of T-cell-mediated IL-2 and TNFα production is linked to decreased CD58 expression in intestinal tissue during acute simian immunodeficiency virus infection.

Pan D, Das A, Srivastav SK, Traina-Dorge V, Didier PJ, Pahar B.

J Gen Virol. 2019 Jan;100(1):26-34. doi: 10.1099/jgv.0.001181. Epub 2018 Nov 29.


The Role of Defensins in HIV Pathogenesis.

Pace BT, Lackner AA, Porter E, Pahar B.

Mediators Inflamm. 2017;2017:5186904. doi: 10.1155/2017/5186904. Epub 2017 Aug 3. Review.


A significant productive in vivo infection of resting cells with simian immunodeficiency virus in a macaque with AIDS.

Pahar B, Lala W, Kuebler D, Liu D.

J Med Primatol. 2017 Apr;46(2):59-62. doi: 10.1111/jmp.12252. Epub 2017 Feb 1.


An HSV-2 Trivalent Vaccine Is Immunogenic in Rhesus Macaques and Highly Efficacious in Guinea Pigs.

Awasthi S, Hook LM, Shaw CE, Pahar B, Stagray JA, Liu D, Veazey RS, Friedman HM.

PLoS Pathog. 2017 Jan 19;13(1):e1006141. doi: 10.1371/journal.ppat.1006141. eCollection 2017 Jan.


Vaccination of rhesus macaques with the live-attenuated HSV-1 vaccine VC2 stimulates the proliferation of mucosal T cells and germinal center responses resulting in sustained production of highly neutralizing antibodies.

Stanfield BA, Pahar B, Chouljenko VN, Veazey R, Kousoulas KG.

Vaccine. 2017 Jan 23;35(4):536-543. doi: 10.1016/j.vaccine.2016.12.018. Epub 2016 Dec 22.


Breadth and magnitude of antigen-specific antibody responses in the control of plasma viremia in simian immunodeficiency virus infected macaques.

Pahar B, Kenway-Lynch CS, Marx P, Srivastav SK, LaBranche C, Montefiori DC, Das A.

Virol J. 2016 Dec 1;13(1):200.


Septicemia in an Indian Rhesus Macaque (Macaca mulatta) associated with Providencia stuartii.

Liu DX, Didier PJ, Plauche G, Pahar B.

J Med Primatol. 2016 Dec;45(6):330-332. doi: 10.1111/jmp.12230. Epub 2016 Jul 28.


Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif.

Breed MW, Elser SE, Torben W, Jordan AP, Aye PP, Midkiff C, Schiro F, Sugimoto C, Alvarez-Hernandez X, Blair RV, Somasunderam A, Utay NS, Kuroda MJ, Pahar B, Wiseman RW, O'Connor DH, LaBranche CC, Montefiori DC, Marsh M, Li Y, Piatak M Jr, Lifson JD, Keele BF, Fultz PN, Lackner AA, Hoxie JA.

J Virol. 2015 Oct;89(20):10156-75. doi: 10.1128/JVI.01134-15. Epub 2015 Jul 29.


Chronic Binge Alcohol Administration Increases Intestinal T-Cell Proliferation and Turnover in Rhesus Macaques.

Veazey RS, Amedee A, Wang X, Bernice Kaack M, Porretta C, Dufour J, Welsh D, Happel K, Pahar B, Molina PE, Nelson S, Bagby GJ.

Alcohol Clin Exp Res. 2015 Aug;39(8):1373-9. doi: 10.1111/acer.12784. Epub 2015 Jul 4.


Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge.

Kutzler MA, Wise MC, Hutnick NA, Moldoveanu Z, Hunter M, Reuter M, Yuan S, Yan J, Ginsberg A, Sylvester A, Pahar B, Carnathan D, Kathuria N, Khan AS, Montefiori D, Sardesai NY, Betts MR, Mestecky J, Marx P, Weiner DB.

Mucosal Immunol. 2016 Jan;9(1):13-23. doi: 10.1038/mi.2015.31. Epub 2015 May 6.


Transforming growth factor-β1 regulated phosphorylated AKT and interferon gamma expressions are associated with epithelial cell survival in rhesus macaque colon explants.

Pahar B, Pan D, Lala W, Kenway-Lynch CS, Das A.

Clin Immunol. 2015 May;158(1):8-18. doi: 10.1016/j.clim.2015.03.001. Epub 2015 Mar 10.


Profound loss of intestinal Tregs in acutely SIV-infected neonatal macaques.

Wang X, Xu H, Shen C, Alvarez X, Liu D, Pahar B, Ratterree MS, Doyle-Meyers LA, Lackner AA, Veazey RS.

J Leukoc Biol. 2015 Feb;97(2):391-400. doi: 10.1189/jlb.4A0514-266RR. Epub 2014 Dec 9.


A single amino acid mutation in the envelope cytoplasmic tail restores the ability of an attenuated simian immunodeficiency virus mutant to deplete mucosal CD4+ T cells.

Breed MW, Jordan AP, Aye PP, Sugimoto C, Alvarez X, Kuroda MJ, Pahar B, Keele BF, Hoxie JA, Lackner AA.

J Virol. 2013 Dec;87(23):13048-52. doi: 10.1128/JVI.02126-13. Epub 2013 Sep 11.


Dynamics of cytokine/chemokine responses in intestinal CD4+ and CD8+ T Cells during Acute Simian Immunodeficiency Virus Infection.

Kenway-Lynch CS, Das A, Pan D, Lackner AA, Pahar B.

J Virol. 2013 Nov;87(21):11916-23. doi: 10.1128/JVI.01750-13. Epub 2013 Aug 21.


Interleukin-10 prevents epithelial cell apoptosis by regulating IFNγ and TNFα expression in rhesus macaque colon explants.

Pan D, Das A, Lala W, Kenway-Lynch CS, Liu DX, Veazey RS, Pahar B.

Cytokine. 2013 Oct;64(1):30-4. doi: 10.1016/j.cyto.2013.06.312. Epub 2013 Jul 15.


Effects of alcohol consumption on antigen-specific cellular and humoral immune responses to SIV in rhesus macaques.

Pahar B, Amedee AM, Thomas J, Dufour JP, Zhang P, Nelson S, Veazey RS, Bagby GJ.

J Acquir Immune Defic Syndr. 2013 Dec 1;64(4):332-41. doi: 10.1097/QAI.0b013e31829f6dca.


Divergent kinetics of proliferating T cell subsets in simian immunodeficiency virus (SIV) infection: SIV eliminates the "first responder" CD4+ T cells in primary infection.

Wang X, Xu H, Pahar B, Lackner AA, Veazey RS.

J Virol. 2013 Jun;87(12):7032-8. doi: 10.1128/JVI.00027-13. Epub 2013 Apr 17.


Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression.

Breed MW, Jordan AP, Aye PP, Lichtveld CF, Midkiff CC, Schiro FR, Haggarty BS, Sugimoto C, Alvarez X, Sandler NG, Douek DC, Kuroda MJ, Pahar B, Piatak M Jr, Lifson JD, Keele BF, Hoxie JA, Lackner AA.

J Virol. 2013 Feb;87(3):1528-43. doi: 10.1128/JVI.01928-12. Epub 2012 Nov 14.


Experimental inoculation of juvenile rhesus macaques with primate enteric caliciviruses.

Sestak K, Feely S, Fey B, Dufour J, Hargitt E, Alvarez X, Pahar B, Gregoricus N, Vinjé J, Farkas T.

PLoS One. 2012;7(5):e37973. doi: 10.1371/journal.pone.0037973. Epub 2012 May 30.


Locally infiltrative ameloblastic fibroma in a rhesus macaque (Macaca mulatta) with characterizations of its proliferating activity and biological behavior.

Liu DX, Doyle LA, Bouljihad MT, Didier PJ, Gilbert MH, Wang X, Pahar B, Bohm RP, Veazey RS, Lackner AA.

J Vet Diagn Invest. 2012 May;24(3):630-5. doi: 10.1177/1040638712443359.


A possible role for inflammation in mediating apoptosis of oligodendrocytes as induced by the Lyme disease spirochete Borrelia burgdorferi.

Ramesh G, Benge S, Pahar B, Philipp MT.

J Neuroinflammation. 2012 Apr 23;9:72. doi: 10.1186/1742-2094-9-72.


Rapid down-regulation of γc on T cells in early SIV infection correlates with impairment of T-cell function.

Xu H, Wang X, Pahar B, Alvarez X, Rasmussen KK, Lackner AA, Veazey RS.

FASEB J. 2012 Jun;26(6):2294-305. doi: 10.1096/fj.11-195180. Epub 2012 Feb 28.


Isolation and characterization of intestinal epithelial cells from normal and SIV-infected rhesus macaques.

Pan D, Das A, Liu D, Veazey RS, Pahar B.

PLoS One. 2012;7(1):e30247. doi: 10.1371/journal.pone.0030247. Epub 2012 Jan 26.


The stress-response factor SigH modulates the interaction between Mycobacterium tuberculosis and host phagocytes.

Dutta NK, Mehra S, Martinez AN, Alvarez X, Renner NA, Morici LA, Pahar B, Maclean AG, Lackner AA, Kaushal D.

PLoS One. 2012;7(1):e28958. doi: 10.1371/journal.pone.0028958. Epub 2012 Jan 3.


Distinct expression patterns of CD69 in mucosal and systemic lymphoid tissues in primary SIV infection of rhesus macaques.

Wang X, Xu H, Alvarez X, Pahar B, Moroney-Rasmussen T, Lackner AA, Veazey RS.

PLoS One. 2011;6(11):e27207. doi: 10.1371/journal.pone.0027207. Epub 2011 Nov 9.


Simian immunodeficiency virus infection in rhesus macaques induces selective tissue specific B cell defects in double positive CD21+CD27+ memory B cells.

Das A, Veazey RS, Wang X, Lackner AA, Xu H, Pahar B.

Clin Immunol. 2011 Sep;140(3):223-8. doi: 10.1016/j.clim.2011.04.018. Epub 2011 May 12.


Early divergent host responses in SHIVsf162P3 and SIVmac251 infected macaques correlate with control of viremia.

Xu H, Wang X, Morici LA, Pahar B, Veazey RS.

PLoS One. 2011 Mar 25;6(3):e17965. doi: 10.1371/journal.pone.0017965.


Double-positive CD21+CD27+ B cells are highly proliferating memory cells and their distribution differs in mucosal and peripheral tissues.

Das A, Xu H, Wang X, Yau CL, Veazey RS, Pahar B.

PLoS One. 2011 Jan 27;6(1):e16524. doi: 10.1371/journal.pone.0016524.


Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression.

Xu H, Wang X, Pahar B, Moroney-Rasmussen T, Alvarez X, Lackner AA, Veazey RS.

J Immunol. 2010 Dec 15;185(12):7340-8. doi: 10.4049/jimmunol.1001642. Epub 2010 Nov 8.


Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas.

Mehra S, Pahar B, Dutta NK, Conerly CN, Philippi-Falkenstein K, Alvarez X, Kaushal D.

PLoS One. 2010 Aug 31;5(8):e12266. doi: 10.1371/journal.pone.0012266.


Simian immunodeficiency virus selectively infects proliferating CD4+ T cells in neonatal rhesus macaques.

Wang X, Xu H, Pahar B, Alvarez X, Green LC, Dufour J, Moroney-Rasmussen T, Lackner AA, Veazey RS.

Blood. 2010 Nov 18;116(20):4168-74. doi: 10.1182/blood-2010-03-273482. Epub 2010 Aug 17.


Recombinant varicella vaccines induce neutralizing antibodies and cellular immune responses to SIV and reduce viral loads in immunized rhesus macaques.

Traina-Dorge V, Pahar B, Marx P, Kissinger P, Montefiori D, Ou Y, Gray WL.

Vaccine. 2010 Sep 7;28(39):6483-90. doi: 10.1016/j.vaccine.2010.07.018. Epub 2010 Jul 21.


Rabies virus-based vaccines elicit neutralizing antibodies, poly-functional CD8+ T cell, and protect rhesus macaques from AIDS-like disease after SIV(mac251) challenge.

Faul EJ, Aye PP, Papaneri AB, Pahar B, McGettigan JP, Schiro F, Chervoneva I, Montefiori DC, Lackner AA, Schnell MJ.

Vaccine. 2009 Dec 11;28(2):299-308. doi: 10.1016/j.vaccine.2009.10.051. Epub 2009 Oct 29.


Monitoring alpha4beta7 integrin expression on circulating CD4+ T cells as a surrogate marker for tracking intestinal CD4+ T-cell loss in SIV infection.

Wang X, Xu H, Gill AF, Pahar B, Kempf D, Rasmussen T, Lackner AA, Veazey RS.

Mucosal Immunol. 2009 Nov;2(6):518-26. doi: 10.1038/mi.2009.104. Epub 2009 Aug 26.


Control of viremia and maintenance of intestinal CD4(+) memory T cells in SHIV(162P3) infected macaques after pathogenic SIV(MAC251) challenge.

Pahar B, Lackner AA, Piatak M Jr, Lifson JD, Wang X, Das A, Ling B, Montefiori DC, Veazey RS.

Virology. 2009 May 10;387(2):273-84. doi: 10.1016/j.virol.2009.02.014. Epub 2009 Mar 18.


Live Borrelia burgdorferi spirochetes elicit inflammatory mediators from human monocytes via the Toll-like receptor signaling pathway.

Dennis VA, Dixit S, O'Brien SM, Alvarez X, Pahar B, Philipp MT.

Infect Immun. 2009 Mar;77(3):1238-45. doi: 10.1128/IAI.01078-08. Epub 2009 Jan 12.


Recombinant vesicular stomatitis virus-based west Nile vaccine elicits strong humoral and cellular immune responses and protects mice against lethal challenge with the virulent west Nile virus strain LSU-AR01.

Iyer AV, Pahar B, Boudreaux MJ, Wakamatsu N, Roy AF, Chouljenko VN, Baghian A, Apetrei C, Marx PA, Kousoulas KG.

Vaccine. 2009 Feb 5;27(6):893-903. doi: 10.1016/j.vaccine.2008.11.087. Epub 2008 Dec 12.


Intestinal double-positive CD4+CD8+ T cells of neonatal rhesus macaques are proliferating, activated memory cells and primary targets for SIVMAC251 infection.

Wang X, Das A, Lackner AA, Veazey RS, Pahar B.

Blood. 2008 Dec 15;112(13):4981-90. doi: 10.1182/blood-2008-05-160077. Epub 2008 Sep 26.


Differential cross-reactivity of monoclonal antibody OPD4 (anti-CD45RO) in macaques.

Wang X, Pahar B, Rasmussen T, Alvarez X, Dufour J, Rasmussen K, Lackner AA, Veazey RS.

Dev Comp Immunol. 2008;32(7):859-68. doi: 10.1016/j.dci.2007.12.009. Epub 2008 Jan 28.


Early restoration of mucosal CD4 memory CCR5 T cells in the gut of SIV-infected rhesus predicts long term non-progression.

Ling B, Veazey RS, Hart M, Lackner AA, Kuroda M, Pahar B, Marx PA.

AIDS. 2007 Nov 30;21(18):2377-85.


A decline in CCL3-5 chemokine gene expression during primary simian-human immunodeficiency virus infection.

Zhao W, Pahar B, Borda JT, Alvarez X, Sestak K.

PLoS One. 2007 Aug 8;2(8):e726.


Virus-specific T cell responses in macaques acutely infected with SHIV(sf162p3).

Pahar B, Wang X, Dufour J, Lackner AA, Veazey RS.

Virology. 2007 Jun 20;363(1):36-47. Epub 2007 Feb 16.


Single epitope mucosal vaccine delivered via immuno-stimulating complexes induces low level of immunity against simian-HIV.

Pahar B, Cantu MA, Zhao W, Kuroda MJ, Veazey RS, Montefiori DC, Clements JD, Aye PP, Lackner AA, Lovgren-Bengtsson K, Sestak K.

Vaccine. 2006 Nov 17;24(47-48):6839-49. Epub 2006 Jul 5.


Supplemental Content

Support Center