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Items: 12


A Fluorescence-Activated Single-Droplet Dispenser for High Accuracy Single-Droplet and Single-Cell Sorting and Dispensing.

Qin Y, Wu L, Wang J, Han R, Shen J, Wang J, Xu S, Paguirigan AL, Smith JL, Radich JP, Chiu DT.

Anal Chem. 2019 May 21;91(10):6815-6819. doi: 10.1021/acs.analchem.9b01017. Epub 2019 May 9.


A Self-Digitization Dielectrophoretic (SD-DEP) Chip for High-Efficiency Single-Cell Capture, On-Demand Compartmentalization, and Downstream Nucleic Acid Analysis.

Qin Y, Wu L, Schneider T, Yen GS, Wang J, Xu S, Li M, Paguirigan AL, Smith JL, Radich JP, Anand RK, Chiu DT.

Angew Chem Int Ed Engl. 2018 Aug 27;57(35):11378-11383. doi: 10.1002/anie.201807314. Epub 2018 Jul 27.


Self-digitization chip for single-cell genotyping of cancer-related mutations.

Thompson AM, Smith JL, Monroe LD, Kreutz JE, Schneider T, Fujimoto BS, Chiu DT, Radich JP, Paguirigan AL.

PLoS One. 2018 May 2;13(5):e0196801. doi: 10.1371/journal.pone.0196801. eCollection 2018.


Optical painting and fluorescence activated sorting of single adherent cells labelled with photoswitchable Pdots.

Kuo CT, Thompson AM, Gallina ME, Ye F, Johnson ES, Sun W, Zhao M, Yu J, Wu IC, Fujimoto B, DuFort CC, Carlson MA, Hingorani SR, Paguirigan AL, Radich JP, Chiu DT.

Nat Commun. 2016 Apr 27;7:11468. doi: 10.1038/ncomms11468.


Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia.

Paguirigan AL, Smith J, Meshinchi S, Carroll M, Maley C, Radich JP.

Sci Transl Med. 2015 Apr 1;7(281):281re2. doi: 10.1126/scitranslmed.aaa0763.


Self-digitization microfluidic chip for absolute quantification of mRNA in single cells.

Thompson AM, Gansen A, Paguirigan AL, Kreutz JE, Radich JP, Chiu DT.

Anal Chem. 2014 Dec 16;86(24):12308-14. doi: 10.1021/ac5035924. Epub 2014 Nov 25.


Microfluidics for single-cell genetic analysis.

Thompson AM, Paguirigan AL, Kreutz JE, Radich JP, Chiu DT.

Lab Chip. 2014 Sep 7;14(17):3135-42. doi: 10.1039/c4lc00175c.


Expanding the available assays: adapting and validating In-Cell Westerns in microfluidic devices for cell-based assays.

Paguirigan AL, Puccinelli JP, Su X, Beebe DJ.

Assay Drug Dev Technol. 2010 Oct;8(5):591-601. doi: 10.1089/adt.2010.0274. Epub 2010 Jul 26.


From the cellular perspective: exploring differences in the cellular baseline in macroscale and microfluidic cultures.

Paguirigan AL, Beebe DJ.

Integr Biol (Camb). 2009 Feb;1(2):182-95. doi: 10.1039/b814565b. Epub 2009 Jan 8. Review.


An adaptable hydrogel array format for 3-dimensional cell culture and analysis.

Jongpaiboonkit L, King WJ, Lyons GE, Paguirigan AL, Warrick JW, Beebe DJ, Murphy WL.

Biomaterials. 2008 Aug;29(23):3346-56. doi: 10.1016/j.biomaterials.2008.04.040. Epub 2008 May 16.


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