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Items: 43

1.

CHL1 gene acts as a tumor suppressor in human neuroblastoma.

Ognibene M, Pagnan G, Marimpietri D, Cangelosi D, Cilli M, Benedetti MC, Boldrini R, Garaventa A, Frassoni F, Eva A, Varesio L, Pistoia V, Pezzolo A.

Oncotarget. 2018 May 25;9(40):25903-25921. doi: 10.18632/oncotarget.25403. eCollection 2018 May 25.

2.

Tumor vascular targeted liposomal-bortezomib minimizes side effects and increases therapeutic activity in human neuroblastoma.

Zuccari G, Milelli A, Pastorino F, Loi M, Petretto A, Parise A, Marchetti C, Minarini A, Cilli M, Emionite L, Di Paolo D, Brignole C, Piaggio F, Perri P, Tumiatti V, Pistoia V, Pagnan G, Ponzoni M.

J Control Release. 2015 Aug 10;211:44-52. doi: 10.1016/j.jconrel.2015.05.286. Epub 2015 May 29.

PMID:
26031842
3.

The interleukin (IL)-31/IL-31R axis contributes to tumor growth in human follicular lymphoma.

Ferretti E, Tripodo C, Pagnan G, Guarnotta C, Marimpietri D, Corrias MV, Ribatti D, Zupo S, Fraternali-Orcioni G, Ravetti JL, Pistoia V, Corcione A.

Leukemia. 2015 Apr;29(4):958-67. doi: 10.1038/leu.2014.291. Epub 2014 Oct 6.

PMID:
25283844
4.

Nanocarrier-mediated targeting of tumor and tumor vascular cells improves uptake and penetration of drugs into neuroblastoma.

Pastorino F, Brignole C, Loi M, Di Paolo D, Di Fiore A, Perri P, Pagnan G, Ponzoni M.

Front Oncol. 2013 Aug 5;3:190. doi: 10.3389/fonc.2013.00190. eCollection 2013.

5.

Enhanced anti-tumor and anti-angiogenic efficacy of a novel liposomal fenretinide on human neuroblastoma.

Di Paolo D, Pastorino F, Zuccari G, Caffa I, Loi M, Marimpietri D, Brignole C, Perri P, Cilli M, Nico B, Ribatti D, Pistoia V, Ponzoni M, Pagnan G.

J Control Release. 2013 Sep 28;170(3):445-51. doi: 10.1016/j.jconrel.2013.06.015. Epub 2013 Jun 19.

PMID:
23792118
6.

The use of the orthotopic model to validate antivascular therapies for cancer.

Loi M, Di Paolo D, Becherini P, Zorzoli A, Perri P, Carosio R, Cilli M, Ribatti D, Brignole C, Pagnan G, Ponzoni M, Pastorino F.

Int J Dev Biol. 2011;55(4-5):547-55. doi: 10.1387/ijdb.103230ml. Review.

7.

Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma.

Di Paolo D, Ambrogio C, Pastorino F, Brignole C, Martinengo C, Carosio R, Loi M, Pagnan G, Emionite L, Cilli M, Ribatti D, Allen TM, Chiarle R, Ponzoni M, Perri P.

Mol Ther. 2011 Dec;19(12):2201-12. doi: 10.1038/mt.2011.142. Epub 2011 Aug 9.

8.

Neuroblastoma-targeted nanoparticles entrapping siRNA specifically knockdown ALK.

Di Paolo D, Brignole C, Pastorino F, Carosio R, Zorzoli A, Rossi M, Loi M, Pagnan G, Emionite L, Cilli M, Bruno S, Chiarle R, Allen TM, Ponzoni M, Perri P.

Mol Ther. 2011 Jun;19(6):1131-40. doi: 10.1038/mt.2011.54. Epub 2011 Apr 12.

9.

Therapeutic targeting of TLR9 inhibits cell growth and induces apoptosis in neuroblastoma.

Brignole C, Marimpietri D, Di Paolo D, Perri P, Morandi F, Pastorino F, Zorzoli A, Pagnan G, Loi M, Caffa I, Erminio G, Haupt R, Gambini C, Pistoia V, Ponzoni M.

Cancer Res. 2010 Dec 1;70(23):9816-26. doi: 10.1158/0008-5472.CAN-10-1251. Epub 2010 Oct 8.

10.

Enhanced anti-tumor activity of a new curcumin-related compound against melanoma and neuroblastoma cells.

Pisano M, Pagnan G, Dettori MA, Cossu S, Caffa I, Sassu I, Emionite L, Fabbri D, Cilli M, Pastorino F, Palmieri G, Delogu G, Ponzoni M, Rozzo C.

Mol Cancer. 2010 Jun 3;9:137. doi: 10.1186/1476-4598-9-137.

11.

Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma.

Loi M, MarchiĆ² S, Becherini P, Di Paolo D, Soster M, Curnis F, Brignole C, Pagnan G, Perri P, Caffa I, Longhi R, Nico B, Bussolino F, Gambini C, Ribatti D, Cilli M, Arap W, Pasqualini R, Allen TM, Corti A, Ponzoni M, Pastorino F.

J Control Release. 2010 Jul 1;145(1):66-73. doi: 10.1016/j.jconrel.2010.03.015. Epub 2010 Mar 24.

PMID:
20346382
12.

Liposome-mediated therapy of neuroblastoma.

Di Paolo D, Loi M, Pastorino F, Brignole C, Marimpietri D, Becherini P, Caffa I, Zorzoli A, Longhi R, Gagliani C, Tacchetti C, Corti A, Allen TM, Ponzoni M, Pagnan G.

Methods Enzymol. 2009;465:225-49. doi: 10.1016/S0076-6879(09)65012-6.

PMID:
19913170
13.

Recent advances in targeted anti-vasculature therapy: the neuroblastoma model.

Pastorino F, Di Paolo D, Loi M, Becherini P, Caffa I, Zorzoli A, Marimpietri D, Carosio R, Perri P, Montaldo PG, Brignole C, Pagnan G, Ribatti D, Allen TM, Ponzoni M.

Curr Drug Targets. 2009 Oct;10(10):1021-7. Review.

PMID:
19663770
14.

Anti-IL-10R antibody improves the therapeutic efficacy of targeted liposomal oligonucleotides.

Brignole C, Marimpietri D, Pastorino F, Di Paolo D, Pagnan G, Loi M, Piccardi F, Cilli M, Tradori-Cappai A, Arrigoni G, Pistoia V, Ponzoni M.

J Control Release. 2009 Sep 1;138(2):122-7. doi: 10.1016/j.jconrel.2009.05.006. Epub 2009 May 7.

PMID:
19427884
15.

The combined therapeutic effects of bortezomib and fenretinide on neuroblastoma cells involve endoplasmic reticulum stress response.

Pagnan G, Di Paolo D, Carosio R, Pastorino F, Marimpietri D, Brignole C, Pezzolo A, Loi M, Galietta LJ, Piccardi F, Cilli M, Nico B, Ribatti D, Pistoia V, Ponzoni M.

Clin Cancer Res. 2009 Feb 15;15(4):1199-209. doi: 10.1158/1078-0432.CCR-08-2477.

16.

Enhanced antitumor efficacy of clinical-grade vasculature-targeted liposomal doxorubicin.

Pastorino F, Di Paolo D, Piccardi F, Nico B, Ribatti D, Daga A, Baio G, Neumaier CE, Brignole C, Loi M, Marimpietri D, Pagnan G, Cilli M, Lepekhin EA, Garde SV, Longhi R, Corti A, Allen TM, Wu JJ, Ponzoni M.

Clin Cancer Res. 2008 Nov 15;14(22):7320-9. doi: 10.1158/1078-0432.CCR-08-0804.

17.

Drug delivery systems: application of liposomal anti-tumor agents to neuroectodermal cancer treatment.

Di Paolo D, Pastorino F, Brignole C, Marimpietri D, Loi M, Ponzoni M, Pagnan G.

Tumori. 2008 Mar-Apr;94(2):246-53.

PMID:
18564613
18.

Ligand-targeted liposomal therapies of neuroblastoma.

Pastorino F, Marimpietri D, Brignole C, Di Paolo D, Pagnan G, Daga A, Piccardi F, Cilli M, Allen TM, Ponzoni M.

Curr Med Chem. 2007;14(29):3070-8. Review.

PMID:
18220743
19.

Combined therapeutic effects of vinblastine and rapamycin on human neuroblastoma growth, apoptosis, and angiogenesis.

Marimpietri D, Brignole C, Nico B, Pastorino F, Pezzolo A, Piccardi F, Cilli M, Di Paolo D, Pagnan G, Longo L, Perri P, Ribatti D, Ponzoni M.

Clin Cancer Res. 2007 Jul 1;13(13):3977-88.

20.

Antiproliferative and pro-apoptotic activity of eugenol-related biphenyls on malignant melanoma cells.

Pisano M, Pagnan G, Loi M, Mura ME, Tilocca MG, Palmieri G, Fabbri D, Dettori MA, Delogu G, Ponzoni M, Rozzo C.

Mol Cancer. 2007 Jan 18;6:8.

21.

Targeting liposomal chemotherapy via both tumor cell-specific and tumor vasculature-specific ligands potentiates therapeutic efficacy.

Pastorino F, Brignole C, Di Paolo D, Nico B, Pezzolo A, Marimpietri D, Pagnan G, Piccardi F, Cilli M, Longhi R, Ribatti D, Corti A, Allen TM, Ponzoni M.

Cancer Res. 2006 Oct 15;66(20):10073-82.

22.

An interferon-sensitive response element is involved in constitutive caspase-8 gene expression in neuroblastoma cells.

De Ambrosis A, Casciano I, Croce M, Pagnan G, Radic L, Banelli B, Di Vinci A, Allemanni G, Tonini GP, Ponzoni M, Romani M, Ferrini S.

Int J Cancer. 2007 Jan 1;120(1):39-47.

23.

Effect of bortezomib on human neuroblastoma cell growth, apoptosis, and angiogenesis.

Brignole C, Marimpietri D, Pastorino F, Nico B, Di Paolo D, Cioni M, Piccardi F, Cilli M, Pezzolo A, Corrias MV, Pistoia V, Ribatti D, Pagnan G, Ponzoni M.

J Natl Cancer Inst. 2006 Aug 16;98(16):1142-57.

PMID:
16912267
24.

Neuroblastoma targeting by c-myb-selective antisense oligonucleotides entrapped in anti-GD2 immunoliposome: immune cell-mediated anti-tumor activities.

Brignole C, Marimpietri D, Pagnan G, Di Paolo D, Zancolli M, Pistoia V, Ponzoni M, Pastorino F.

Cancer Lett. 2005 Oct 18;228(1-2):181-6. Review.

PMID:
15936140
25.

Caspase-8 gene expression in neuroblastoma.

Casciano I, Banelli B, Croce M, De Ambrosis A, di Vinci A, Gelvi I, Pagnan G, Brignole C, Allemanni G, Ferrini S, Ponzoni M, Romani M.

Ann N Y Acad Sci. 2004 Dec;1028:157-67.

PMID:
15650242
26.

Targeted delivery of oncogene-selective antisense oligonucleotides in neuroectodermal tumors: therapeutic implications.

Pastorino F, Brignole C, Marimpietri D, Di Paolo D, Zancolli M, Pagnan G, Ponzoni M.

Ann N Y Acad Sci. 2004 Dec;1028:90-103.

PMID:
15650235
27.

Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-{kappa}B and Mat1A genes in the early stages of rat liver carcinogenesis.

Simile MM, Pagnan G, Pastorino F, Brignole C, De Miglio MR, Muroni MR, Asara G, Frau M, Seddaiu MA, Calvisi DF, Feo F, Ponzoni M, Pascale RM.

Carcinogenesis. 2005 Feb;26(2):417-27. Epub 2004 Oct 21.

PMID:
15498786
28.

Immune cell-mediated antitumor activities of GD2-targeted liposomal c-myb antisense oligonucleotides containing CpG motifs.

Brignole C, Pastorino F, Marimpietri D, Pagnan G, Pistorio A, Allen TM, Pistoia V, Ponzoni M.

J Natl Cancer Inst. 2004 Aug 4;96(15):1171-80.

PMID:
15292389
29.

Expression of the caspase-8 gene in neuroblastoma cells is regulated through an essential interferon-sensitive response element (ISRE).

Casciano I, De Ambrosis A, Croce M, Pagnan G, Di Vinci A, Allemanni G, Banelli B, Ponzoni M, Romani M, Ferrini S.

Cell Death Differ. 2004 Jan;11(1):131-4. No abstract available.

30.

Targeted liposomal c-myc antisense oligodeoxynucleotides induce apoptosis and inhibit tumor growth and metastases in human melanoma models.

Pastorino F, Brignole C, Marimpietri D, Pagnan G, Morando A, Ribatti D, Semple SC, Gambini C, Allen TM, Ponzoni M.

Clin Cancer Res. 2003 Oct 1;9(12):4595-605.

31.

Targeted delivery system for antisense oligonucleotides: a novel experimental strategy for neuroblastoma treatment.

Brignole C, Pagnan G, Marimpietri D, Cosimo E, Allen TM, Ponzoni M, Pastorino F.

Cancer Lett. 2003 Jul 18;197(1-2):231-5. Review.

PMID:
12880987
32.

Anti-GD2 monoclonal antibody immunotherapy: a promising strategy in the prevention of neuroblastoma relapse.

Raffaghello L, Marimpietri D, Pagnan G, Pastorino F, Cosimo E, Brignole C, Ponzoni M, Montaldo PG.

Cancer Lett. 2003 Jul 18;197(1-2):205-9. Review.

PMID:
12880983
33.

Immunoliposomal fenretinide: a novel antitumoral drug for human neuroblastoma.

Raffaghello L, Pagnan G, Pastorino F, Cosimo E, Brignole C, Marimpietri D, Bogenmann E, Ponzoni M, Montaldo PG.

Cancer Lett. 2003 Jul 18;197(1-2):151-5. Review.

PMID:
12880975
34.

Biological and clinical role of p73 in neuroblastoma.

Romani M, Tonini GP, Banelli B, Allemanni G, Mazzocco K, Scaruffi P, Boni L, Ponzoni M, Pagnan G, Raffaghello L, Ferrini S, Croce M, Casciano I.

Cancer Lett. 2003 Jul 18;197(1-2):111-7. Review.

PMID:
12880969
35.

In vitro and in vivo antitumor activity of liposomal Fenretinide targeted to human neuroblastoma.

Raffaghello L, Pagnan G, Pastorino F, Cosimo E, Brignole C, Marimpietri D, Montaldo PG, Gambini C, Allen TM, Bogenmann E, Ponzoni M.

Int J Cancer. 2003 May 1;104(5):559-67.

36.
37.

Expression and methylation of CASP8 in neuroblastoma: identification of a promoter region.

Banelli B, Casciano I, Croce M, Di Vinci A, Gelvi I, Pagnan G, Brignole C, Allemanni G, Ferrini S, Ponzoni M, Romani M.

Nat Med. 2002 Dec;8(12):1333-5; author reply 1335. No abstract available.

PMID:
12457155
38.

Expression of DeltaNp73 is a molecular marker for adverse outcome in neuroblastoma patients.

Casciano I, Mazzocco K, Boni L, Pagnan G, Banelli B, Allemanni G, Ponzoni M, Tonini GP, Romani M.

Cell Death Differ. 2002 Mar;9(3):246-51.

39.

Delivery of c-myb antisense oligodeoxynucleotides to human neuroblastoma cells via disialoganglioside GD(2)-targeted immunoliposomes: antitumor effects.

Pagnan G, Stuart DD, Pastorino F, Raffaghello L, Montaldo PG, Allen TM, Calabretta B, Ponzoni M.

J Natl Cancer Inst. 2000 Feb 2;92(3):253-61.

PMID:
10655443
40.

GD2-mediated melanoma cell targeting and cytotoxicity of liposome-entrapped fenretinide.

Pagnan G, Montaldo PG, Pastorino F, Raffaghello L, Kirchmeier M, Allen TM, Ponzoni M.

Int J Cancer. 1999 Apr 12;81(2):268-74.

41.

N-(4-hydroxyphenyl) retinamide is cytotoxic to melanoma cells in vitro through induction of programmed cell death.

Montaldo PG, Pagnan G, Pastorino F, Chiesa V, Raffaghello L, Kirchmeier M, Allen TM, Ponzoni M.

Int J Cancer. 1999 Apr 12;81(2):262-7.

42.

Induction of apoptosis in human neuroblastoma cells by abrogation of integrin-mediated cell adhesion.

Rozzo C, Chiesa V, Caridi G, Pagnan G, Ponzoni M.

Int J Cancer. 1997 Mar 17;70(6):688-98.

43.

Potentiation of topoisomerase I and II inhibitors cell killing by tumor necrosis factor: relationship to DNA strand breakage formation.

Orengo G, Noviello E, Cimoli G, Pagnan G, Parodi S, Venturini M, Conte P, Schenone F, Conzi G, Russo P.

Jpn J Cancer Res. 1992 Nov;83(11):1132-6.

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