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Items: 16


Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: studies in mice and FH children.

Tolani S, Pagler TA, Murphy AJ, Bochem AE, Abramowicz S, Welch C, Nagareddy PR, Holleran S, Hovingh GK, Kuivenhoven JA, Tall AR.

Atherosclerosis. 2013 Jul;229(1):79-85. doi: 10.1016/j.atherosclerosis.2013.03.031. Epub 2013 Apr 19.


Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.

Westerterp M, Murphy AJ, Wang M, Pagler TA, Vengrenyuk Y, Kappus MS, Gorman DJ, Nagareddy PR, Zhu X, Abramowicz S, Parks JS, Welch C, Fisher EA, Wang N, Yvan-Charvet L, Tall AR.

Circ Res. 2013 May 24;112(11):1456-65. doi: 10.1161/CIRCRESAHA.113.301086. Epub 2013 Apr 9.


ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice.

Murphy AJ, Akhtari M, Tolani S, Pagler T, Bijl N, Kuo CL, Wang M, Sanson M, Abramowicz S, Welch C, Bochem AE, Kuivenhoven JA, Yvan-Charvet L, Tall AR.

J Clin Invest. 2011 Oct;121(10):4138-49. doi: 10.1172/JCI57559.


Deletion of ABCA1 and ABCG1 impairs macrophage migration because of increased Rac1 signaling.

Pagler TA, Wang M, Mondal M, Murphy AJ, Westerterp M, Moore KJ, Maxfield FR, Tall AR.

Circ Res. 2011 Jan 21;108(2):194-200. doi: 10.1161/CIRCRESAHA.110.228619. Epub 2010 Dec 9.


ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation.

Yvan-Charvet L, Pagler T, Gautier EL, Avagyan S, Siry RL, Han S, Welch CL, Wang N, Randolph GJ, Snoeck HW, Tall AR.

Science. 2010 Jun 25;328(5986):1689-93. doi: 10.1126/science.1189731. Epub 2010 May 20.


Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib.

Yvan-Charvet L, Kling J, Pagler T, Li H, Hubbard B, Fisher T, Sparrow CP, Taggart AK, Tall AR.

Arterioscler Thromb Vasc Biol. 2010 Jul;30(7):1430-8. doi: 10.1161/ATVBAHA.110.207142. Epub 2010 May 6.


ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis.

Yvan-Charvet L, Pagler TA, Seimon TA, Thorp E, Welch CL, Witztum JL, Tabas I, Tall AR.

Circ Res. 2010 Jun 25;106(12):1861-9. doi: 10.1161/CIRCRESAHA.110.217281. Epub 2010 Apr 29.


Characterization of endocytic compartments after holo-high density lipoprotein particle uptake in HepG2 cells.

Röhrl C, Pagler TA, Strobl W, Ellinger A, Neumüller J, Pavelka M, Stangl H, Meisslitzer-Ruppitsch C.

Histochem Cell Biol. 2010 Mar;133(3):261-72. doi: 10.1007/s00418-009-0672-3. Epub 2009 Dec 29.


ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet.

Terasaka N, Yu S, Yvan-Charvet L, Wang N, Mzhavia N, Langlois R, Pagler T, Li R, Welch CL, Goldberg IJ, Tall AR.

J Clin Invest. 2008 Nov;118(11):3701-13. doi: 10.1172/JCI35470. Epub 2008 Oct 16.


Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions.

Yvan-Charvet L, Welch C, Pagler TA, Ranalletta M, Lamkanfi M, Han S, Ishibashi M, Li R, Wang N, Tall AR.

Circulation. 2008 Oct 28;118(18):1837-47. doi: 10.1161/CIRCULATIONAHA.108.793869. Epub 2008 Oct 13.


HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis.

Tall AR, Yvan-Charvet L, Terasaka N, Pagler T, Wang N.

Cell Metab. 2008 May;7(5):365-75. doi: 10.1016/j.cmet.2008.03.001. Review.


SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL.

Yvan-Charvet L, Pagler TA, Wang N, Senokuchi T, Brundert M, Li H, Rinninger F, Tall AR.

J Lipid Res. 2008 Jan;49(1):107-14. Epub 2007 Oct 24.


Cholesterol efflux via HDL resecretion occurs when cholesterol transport out of the lysosome is impaired.

Pagler TA, Neuhofer A, Laggner H, Strobl W, Stangl H.

J Lipid Res. 2007 Oct;48(10):2141-50. Epub 2007 Jul 9.


A Chinese hamster ovarian cell line imports cholesterol by high density lipoprotein degradation.

Pagler TA, Golsabahi S, Doringer M, Rhode S, Schütz GJ, Pavelka M, Wadsack C, Gauster M, Lohninger A, Laggner H, Strobl W, Stangl H.

J Biol Chem. 2006 Dec 15;281(50):38159-71. Epub 2006 Oct 12.


SR-BI-mediated high density lipoprotein (HDL) endocytosis leads to HDL resecretion facilitating cholesterol efflux.

Pagler TA, Rhode S, Neuhofer A, Laggner H, Strobl W, Hinterndorfer C, Volf I, Pavelka M, Eckhardt ER, van der Westhuyzen DR, Schütz GJ, Stangl H.

J Biol Chem. 2006 Apr 21;281(16):11193-204. Epub 2006 Feb 16.


Visualization of the uptake of individual HDL particles in living cells via the scavenger receptor class B type I.

Rhode S, Breuer A, Hesse J, Sonnleitner M, Pagler TA, Doringer M, Schütz GJ, Stangl H.

Cell Biochem Biophys. 2004;41(3):343-56.


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