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Items: 1 to 50 of 113

1.

The influence of patient sex on clinical approaches to malignant glioma.

Matteoni S, Abbruzzese C, Villani V, Malorni W, Pace A, Matarrese P, Paggi MG.

Cancer Lett. 2020 Jan 1;468:41-47. doi: 10.1016/j.canlet.2019.10.012. Epub 2019 Oct 9.

PMID:
31605777
2.

The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells.

Matteoni S, Abbruzzese C, Matarrese P, De Luca G, Mileo AM, Miccadei S, Schenone S, Musumeci F, Haas TL, Sette G, Carapella CM, Amato R, Perrotti N, Signore M, Paggi MG.

J Exp Clin Cancer Res. 2019 May 17;38(1):202. doi: 10.1186/s13046-019-1212-1.

3.

The small molecule SI113 hinders epithelial-to-mesenchymal transition and subverts cytoskeletal organization in human cancer cells.

Abbruzzese C, Matteoni S, Persico M, Ascione B, Schenone S, Musumeci F, Amato R, Perrotti N, Matarrese P, Paggi MG.

J Cell Physiol. 2019 Dec;234(12):22529-22542. doi: 10.1002/jcp.28816. Epub 2019 May 16.

PMID:
31099037
4.

The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme.

Abbruzzese C, Catalogna G, Gallo E, di Martino S, Mileo AM, Carosi M, Dattilo V, Schenone S, Musumeci F, Lavia P, Perrotti N, Amato R, Paggi MG.

Oncotarget. 2017 Nov 18;8(67):110743-110755. doi: 10.18632/oncotarget.22500. eCollection 2017 Dec 19.

5.

Drug repurposing for the treatment of glioblastoma multiforme.

Abbruzzese C, Matteoni S, Signore M, Cardone L, Nath K, Glickson JD, Paggi MG.

J Exp Clin Cancer Res. 2017 Nov 28;36(1):169. doi: 10.1186/s13046-017-0642-x. Review.

6.

Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness.

Matarrese P, Abbruzzese C, Mileo AM, Vona R, Ascione B, Visca P, Rollo F, Benevolo M, Malorni W, Paggi MG.

Oncotarget. 2016 Aug 9;7(32):50972-50985. doi: 10.18632/oncotarget.8646.

7.

SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells.

Talarico C, Dattilo V, D'Antona L, Barone A, Amodio N, Belviso S, Musumeci F, Abbruzzese C, Bianco C, Trapasso F, Schenone S, Alcaro S, Ortuso F, Florio T, Paggi MG, Perrotti N, Amato R.

Oncotarget. 2016 Mar 29;7(13):15868-84. doi: 10.18632/oncotarget.7520.

8.

Hepatitis C virus core protein modulates pRb2/p130 expression in human hepatocellular carcinoma cell lines through promoter methylation.

Mileo AM, Mattarocci S, Matarrese P, Anticoli S, Abbruzzese C, Catone S, Sacco R, Paggi MG, Ruggieri A.

J Exp Clin Cancer Res. 2015 Nov 14;34:140. doi: 10.1186/s13046-015-0255-1.

9.

Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy.

Talarico C, D'Antona L, Scumaci D, Barone A, Gigliotti F, Fiumara CV, Dattilo V, Gallo E, Visca P, Ortuso F, Abbruzzese C, Botta L, Schenone S, Cuda G, Alcaro S, Bianco C, Lavia P, Paggi MG, Perrotti N, Amato R.

Oncotarget. 2015 Nov 10;6(35):37511-25. doi: 10.18632/oncotarget.5527.

10.

SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation.

D'Antona L, Amato R, Talarico C, Ortuso F, Menniti M, Dattilo V, Iuliano R, Gigliotti F, Artese A, Costa G, Schenone S, Musumeci F, Abbruzzese C, Botta L, Trapasso F, Alcaro S, Paggi MG, Perrotti N.

Cell Physiol Biochem. 2015;35(5):2006-18. doi: 10.1159/000374008. Epub 2015 Mar 27.

11.

Detection of phosphorylated insulin receptor in colorectal adenoma and adenocarcinoma: implications for prognosis and clinical outcome.

Abbruzzese C, Diodoro MG, Sperduti I, Mileo AM, Pattaro G, De Salvo L, Cosimelli M, Perrotti N, Paggi MG.

J Cell Physiol. 2015 Mar;230(3):562-7. doi: 10.1002/jcp.24733.

PMID:
25102778
12.

Identification of pivotal cellular factors involved in HPV-induced dysplastic and neoplastic cervical pathologies.

Mattarocci S, Abbruzzese C, Mileo AM, Carosi M, Pescarmona E, Vico C, Federico A, Vizza E, Corrado G, Arisi I, Felsani A, Paggi MG.

J Cell Physiol. 2014 Apr;229(4):463-70. doi: 10.1002/jcp.24465.

PMID:
24105779
13.

The human papillomavirus-16 E7 oncoprotein exerts antiapoptotic effects via its physical interaction with the actin-binding protein gelsolin.

Mileo AM, Abbruzzese C, Vico C, Bellacchio E, Matarrese P, Ascione B, Federico A, Della Bianca S, Mattarocci S, Malorni W, Paggi MG.

Carcinogenesis. 2013 Oct;34(10):2424-33. doi: 10.1093/carcin/bgt192. Epub 2013 Jun 1.

PMID:
23729654
14.

Sgk1 enhances RANBP1 transcript levels and decreases taxol sensitivity in RKO colon carcinoma cells.

Amato R, Scumaci D, D'Antona L, Iuliano R, Menniti M, Di Sanzo M, Faniello MC, Colao E, Malatesta P, Zingone A, Agosti V, Costanzo FS, Mileo AM, Paggi MG, Lang F, Cuda G, Lavia P, Perrotti N.

Oncogene. 2013 Sep 19;32(38):4572-8. doi: 10.1038/onc.2012.470. Epub 2012 Oct 29.

PMID:
23108393
15.

Androgen receptor serine 81 mediates Pin1 interaction and activity.

La Montagna R, Caligiuri I, Maranta P, Lucchetti C, Esposito L, Paggi MG, Toffoli G, Rizzolio F, Giordano A.

Cell Cycle. 2012 Sep 15;11(18):3415-20. doi: 10.4161/cc.21730. Epub 2012 Aug 16.

16.

Understanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinery.

Bellacchio E, Paggi MG.

J Cell Physiol. 2013 Feb;228(2):285-91. doi: 10.1002/jcp.24137. Review.

PMID:
22718244
17.

Effects of assessing the productivity of faculty in academic medical centres: a systematic review.

Akl EA, Meerpohl JJ, Raad D, Piaggio G, Mattioni M, Paggi MG, Gurtner A, Mattarocci S, Tahir R, Muti P, Schünemann HJ.

CMAJ. 2012 Aug 7;184(11):E602-12. doi: 10.1503/cmaj.111123. Epub 2012 May 28. Review.

18.

Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas.

Abbruzzese C, Mattarocci S, Pizzuti L, Mileo AM, Visca P, Antoniani B, Alessandrini G, Facciolo F, Amato R, D'Antona L, Rinaldi M, Felsani A, Perrotti N, Paggi MG.

J Exp Clin Cancer Res. 2012 Jan 12;31:4. doi: 10.1186/1756-9966-31-4.

19.

New insights in endometrial carcinogenesis.

D'Andrilli G, Bovicelli A, Paggi MG, Giordano A.

J Cell Physiol. 2012 Jul;227(7):2842-6. doi: 10.1002/jcp.24016. Review.

PMID:
22105917
20.

Wasting lives: the effects of toxic waste exposure on health. The case of Campania, Southern Italy.

Barba M, Mazza A, Guerriero C, Di Maio M, Romeo F, Maranta P, Marino IR, Paggi MG, Giordano A.

Cancer Biol Ther. 2011 Jul 15;12(2):106-11. Epub 2011 Jul 15. Review.

21.

Reducing the risk of overdiagnosis in lung cancer: a support from molecular biology.

Barba M, Felsani A, Rinaldi M, Giunta S, Malorni W, Paggi MG.

J Cell Physiol. 2011 Sep;226(9):2213-4. doi: 10.1002/jcp.22558.

PMID:
21660943
22.

Identification of protein-protein interactions of human HtrA1.

Campioni M, Severino A, Manente L, De Luca A, La Porta R, Vitiello A, Fiore P, Toldo S, Spugnini EP, Paggi MG, Baldi A.

Front Biosci (Elite Ed). 2011 Jun 1;3:1493-9.

PMID:
21622153
23.

Retinoblastoma-independent antiproliferative activity of novel intracellular antibodies against the E7 oncoprotein in HPV 16-positive cells.

Accardi L, Donà MG, Mileo AM, Paggi MG, Federico A, Torreri P, Petrucci TC, Accardi R, Pim D, Tommasino M, Banks L, Chirullo B, Giorgi C.

BMC Cancer. 2011 Jan 17;11:17. doi: 10.1186/1471-2407-11-17.

24.

Gender-related disparities in non-small cell lung cancer.

Paggi MG, Vona R, Abbruzzese C, Malorni W.

Cancer Lett. 2010 Dec 1;298(1):1-8. doi: 10.1016/j.canlet.2010.08.009. Epub 2010 Sep 9. Review.

PMID:
20826048
25.

Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study.

Matarrese P, Ascione B, Ciarlo L, Vona R, Leonetti C, Scarsella M, Mileo AM, Catricalà C, Paggi MG, Malorni W.

Mol Cancer. 2010 Aug 4;9:207. doi: 10.1186/1476-4598-9-207.

26.

The bad and the good of mesenchymal stem cells in cancer: Boosters of tumor growth and vehicles for targeted delivery of anticancer agents.

Galderisi U, Giordano A, Paggi MG.

World J Stem Cells. 2010 Feb 26;2(1):5-12. doi: 10.4252/wjsc.v2.i1.5.

27.

Human papillomavirus-16 E7 interacts with glutathione S-transferase P1 and enhances its role in cell survival.

Mileo AM, Abbruzzese C, Mattarocci S, Bellacchio E, Pisano P, Federico A, Maresca V, Picardo M, Giorgi A, Maras B, Schininà ME, Paggi MG.

PLoS One. 2009 Oct 13;4(10):e7254. doi: 10.1371/journal.pone.0007254.

28.

Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.

Amato R, D'Antona L, Porciatti G, Agosti V, Menniti M, Rinaldo C, Costa N, Bellacchio E, Mattarocci S, Fuiano G, Soddu S, Paggi MG, Lang F, Perrotti N.

J Mol Med (Berl). 2009 Dec;87(12):1221-39. doi: 10.1007/s00109-009-0525-5. Epub 2009 Sep 11.

PMID:
19756449
29.

Intracellular presence of insulin and its phosphorylated receptor in non-small cell lung cancer.

Mattarocci S, Abbruzzese C, Mileo AM, Visca P, Antoniani B, Alessandrini G, Facciolo F, Felsani A, Radulescu RT, Paggi MG.

J Cell Physiol. 2009 Dec;221(3):766-70. doi: 10.1002/jcp.21916.

PMID:
19688775
30.

Correlation between melanogenic and catalase activity in in vitro human melanocytes: a synergic strategy against oxidative stress.

Maresca V, Flori E, Briganti S, Mastrofrancesco A, Fabbri C, Mileo AM, Paggi MG, Picardo M.

Pigment Cell Melanoma Res. 2008 Apr;21(2):200-5. doi: 10.1111/j.1755-148X.2007.00432.x.

PMID:
18426413
31.
32.

Interaction between the Cdk2/cyclin A complex and a small molecule derived from the pRb2/p130 spacer domain: a theoretical model.

Giordano A, Bellacchio E, Bagella L, Paggi MG.

Cell Cycle. 2007 Nov 1;6(21):2591-3. Epub 2007 Aug 13.

PMID:
17726381
33.

New technologies used in the study of human melanoma.

Felsani A, Mileo AM, Maresca V, Picardo M, Paggi MG.

Int Rev Cytol. 2007;261:247-86. Review.

PMID:
17560284
34.

Human papillomavirus-16 E7 interacts with Siva-1 and modulates apoptosis in HaCaT human immortalized keratinocytes.

Severino A, Abbruzzese C, Manente L, Valderas AA, Mattarocci S, Federico A, Starace G, Chersi A, Mileo AM, Paggi MG.

J Cell Physiol. 2007 Jul;212(1):118-25.

PMID:
17348035
35.

Unravelling the complexity of T cell abnormalities in common variable immunodeficiency.

Giovannetti A, Pierdominici M, Mazzetta F, Marziali M, Renzi C, Mileo AM, De Felice M, Mora B, Esposito A, Carello R, Pizzuti A, Paggi MG, Paganelli R, Malorni W, Aiuti F.

J Immunol. 2007 Mar 15;178(6):3932-43.

36.

Multiple interference of the human papillomavirus-16 E7 oncoprotein with the functional role of the metastasis suppressor Nm23-H1 protein.

Mileo AM, Piombino E, Severino A, Tritarelli A, Paggi MG, Lombardi D.

J Bioenerg Biomembr. 2006 Aug;38(3-4):215-25.

PMID:
17103045
37.

A small molecule based on the pRb2/p130 spacer domain leads to inhibition of cdk2 activity, cell cycle arrest and tumor growth reduction in vivo.

Bagella L, Sun A, Tonini T, Abbadessa G, Cottone G, Paggi MG, De Luca A, Claudio PP, Giordano A.

Oncogene. 2007 Mar 22;26(13):1829-39. Epub 2006 Oct 16.

PMID:
17043661
38.

Retinoblastoma family proteins as key targets of the small DNA virus oncoproteins.

Felsani A, Mileo AM, Paggi MG.

Oncogene. 2006 Aug 28;25(38):5277-85. Review.

PMID:
16936748
39.

Pkn is a novel partner of cyclin T2a in muscle differentiation.

Cottone G, Baldi A, Palescandolo E, Manente L, Penta R, Paggi MG, De Luca A.

J Cell Physiol. 2006 Apr;207(1):232-7.

PMID:
16331689
40.

Ferritin light chain down-modulation generates depigmentation in human metastatic melanoma cells by influencing tyrosinase maturation.

Maresca V, Flori E, Cardinali G, Briganti S, Lombardi D, Mileo AM, Paggi MG, Picardo M.

J Cell Physiol. 2006 Mar;206(3):843-8.

PMID:
16252260
41.

Ferritin contributes to melanoma progression by modulating cell growth and sensitivity to oxidative stress.

Baldi A, Lombardi D, Russo P, Palescandolo E, De Luca A, Santini D, Baldi F, Rossiello L, Dell'Anna ML, Mastrofrancesco A, Maresca V, Flori E, Natali PG, Picardo M, Paggi MG.

Clin Cancer Res. 2005 May 1;11(9):3175-83.

42.

Pattern of expression of HtrA1 during mouse development.

De Luca A, De Falco M, De Luca L, Penta R, Shridhar V, Baldi F, Campioni M, Paggi MG, Baldi A.

J Histochem Cytochem. 2004 Dec;52(12):1609-17.

PMID:
15557215
43.

In vitro and in vivo tumor growth inhibition by a p16-mimicking peptide in p16INK4A-defective, pRb-positive human melanoma cells.

Noonan DM, Severino A, Morini M, Tritarelli A, Manente L, D'Agnano I, Starace G, Baldi A, Lombardi D, Albini A, Felsani A, Paggi MG.

J Cell Physiol. 2005 Mar;202(3):922-8.

PMID:
15389561
44.

The serine protease HtrA1 is upregulated in the human placenta during pregnancy.

De Luca A, De Falco M, Fedele V, Cobellis L, Mastrogiacomo A, Laforgia V, Tuduce IL, Campioni M, Giraldi D, Paggi MG, Baldi A.

J Histochem Cytochem. 2004 Jul;52(7):885-92.

PMID:
15208355
45.

Characterization of tissue specific expression of Notch-1 in human tissues.

Baldi A, De Falco M, De Luca L, Cottone G, Paggi MG, Nickoloff BJ, Miele L, De Luca A.

Biol Cell. 2004 May;96(4):303-11.

PMID:
15145534
46.

Analysis of APAF-1 expression in human cutaneous melanoma progression.

Baldi A, Santini D, Russo P, Catricalà C, Amantea A, Picardo M, Tatangelo F, Botti G, Dragonetti E, Murace R, Tonini G, Natali PG, Baldi F, Paggi MG.

Exp Dermatol. 2004 Feb;13(2):93-7.

PMID:
15009102
47.

RACK1 is a functional target of the E1A oncoprotein.

Severino A, Baldi A, Cottone G, Han M, Sang N, Giordano A, Mileo AM, Paggi MG, De Luca A.

J Cell Physiol. 2004 Apr;199(1):134-9.

PMID:
14978742
48.

Coexpression of Helicobacter pylori's proteins CagA and HspB induces cell proliferation in AGS gastric epithelial cells, independently from the bacterial infection.

De Luca A, Baldi A, Russo P, Todisco A, Altucci L, Giardullo N, Pasquale L, Iaquinto S, D'Onofrio V, Parodi MC, Paggi MG, Iaquinto G.

Cancer Res. 2003 Oct 1;63(19):6350-6.

49.

Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability.

Lavia P, Mileo AM, Giordano A, Paggi MG.

Oncogene. 2003 Sep 29;22(42):6508-16. Review.

PMID:
14528275
50.

Genetic and epigenetic alterations as hallmarks of the intricate road to cancer.

Macaluso M, Paggi MG, Giordano A.

Oncogene. 2003 Sep 29;22(42):6472-8. Review.

PMID:
14528270

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