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Items: 21


High-dimensional mass cytometry analysis revealed microenvironment complexity in chronic lymphocytic leukemia.

Wierz M, Janji B, Berchem G, Moussay E, Paggetti J.

Oncoimmunology. 2018 May 24;7(8):e1465167. doi: 10.1080/2162402X.2018.1465167. eCollection 2018.


Driving Natural Killer cells toward the melanoma tumor battlefield: Autophagy as a valuable therapeutic target.

Noman MZ, Paggetti J, Moussay E, Berchem G, Janji B.

Oncoimmunology. 2018 Apr 25;7(8):e1452583. doi: 10.1080/2162402X.2018.1452583. eCollection 2018.


Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia.

Wierz M, Pierson S, Guyonnet L, Viry E, Lequeux A, Oudin A, Niclou SP, Ollert M, Berchem G, Janji B, Guérin C, Paggetti J, Moussay E.

Blood. 2018 Apr 5;131(14):1617-1621. doi: 10.1182/blood-2017-06-792267. Epub 2018 Feb 13. No abstract available.


The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model.

Wierz M, Pierson S, Chouha N, Désaubry L, François JH, Berchem G, Paggetti J, Moussay E.

Haematologica. 2018 Apr;103(4):e154-e157. doi: 10.3324/haematol.2017.175349. Epub 2018 Jan 5. No abstract available.


Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner.

Mgrditchian T, Arakelian T, Paggetti J, Noman MZ, Viry E, Moussay E, Van Moer K, Kreis S, Guerin C, Buart S, Robert C, Borg C, Vielh P, Chouaib S, Berchem G, Janji B.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9271-E9279. doi: 10.1073/pnas.1703921114. Epub 2017 Oct 16.


Tumor-derived exosomes modulate PD-L1 expression in monocytes.

Haderk F, Schulz R, Iskar M, Cid LL, Worst T, Willmund KV, Schulz A, Warnken U, Seiler J, Benner A, Nessling M, Zenz T, Göbel M, Dürig J, Diederichs S, Paggetti J, Moussay E, Stilgenbauer S, Zapatka M, Lichter P, Seiffert M.

Sci Immunol. 2017 Jul 28;2(13). pii: eaah5509. doi: 10.1126/sciimmunol.aah5509.


Hijacker of the Antitumor Immune Response: Autophagy Is Showing Its Worst Facet.

Viry E, Noman MZ, Arakelian T, Lequeux A, Chouaib S, Berchem G, Moussay E, Paggetti J, Janji B.

Front Oncol. 2016 Nov 18;6:246. eCollection 2016. Review.


Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer.

Berchem G, Noman MZ, Bosseler M, Paggetti J, Baconnais S, Le Cam E, Nanbakhsh A, Moussay E, Mami-Chouaib F, Janji B, Chouaib S.

Oncoimmunology. 2015 Jun 24;5(4):e1062968. eCollection 2016 Apr.


The multifaceted role of autophagy in tumor evasion from immune surveillance.

Janji B, Viry E, Moussay E, Paggetti J, Arakelian T, Mgrditchian T, Messai Y, Noman MZ, Van Moer K, Hasmim M, Mami-Chouaib F, Berchem G, Chouaib S.

Oncotarget. 2016 Apr 5;7(14):17591-607. doi: 10.18632/oncotarget.7540. Review.


BCR engagement in CLL: when translation goes wrong.

Paggetti J, Moussay E.

Blood. 2016 Jan 28;127(4):378-80. doi: 10.1182/blood-2015-11-678623.


Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts.

Paggetti J, Haderk F, Seiffert M, Janji B, Distler U, Ammerlaan W, Kim YJ, Adam J, Lichter P, Solary E, Berchem G, Moussay E.

Blood. 2015 Aug 27;126(9):1106-17. doi: 10.1182/blood-2014-12-618025. Epub 2015 Jun 22.


Autophagy: an adaptive metabolic response to stress shaping the antitumor immunity.

Viry E, Paggetti J, Baginska J, Mgrditchian T, Berchem G, Moussay E, Janji B.

Biochem Pharmacol. 2014 Nov 1;92(1):31-42. doi: 10.1016/j.bcp.2014.07.006. Epub 2014 Jul 17. Review.


The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity.

Baginska J, Viry E, Paggetti J, Medves S, Berchem G, Moussay E, Janji B.

Front Immunol. 2013 Dec 25;4:490. doi: 10.3389/fimmu.2013.00490. Review.


Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells.

Largeot A, Paggetti J, Broséus J, Aucagne R, Lagrange B, Martin RZ, Berthelet J, Quéré R, Lucchi G, Ducoroy P, Bastie JN, Delva L.

Biochim Biophys Acta. 2013 Dec;1833(12):3054-3063. doi: 10.1016/j.bbamcr.2013.08.013. Epub 2013 Aug 27.


A role for miR-142-3p in colony-stimulating factor 1-induced monocyte differentiation into macrophages.

Lagrange B, Martin RZ, Droin N, Aucagne R, Paggetti J, Largeot A, Itzykson R, Solary E, Delva L, Bastie JN.

Biochim Biophys Acta. 2013 Aug;1833(8):1936-46. doi: 10.1016/j.bbamcr.2013.04.007. Epub 2013 Apr 17.


Stromal cell-induced miRNA alteration in chronic lymphocytic leukemia: how a minute and unavoidable cell contamination impairs miRNA profiling.

Paggetti J, Berchem G, Moussay E.

Leukemia. 2013 Aug;27(8):1773-6. doi: 10.1038/leu.2013.43. Epub 2013 Feb 14. No abstract available.


Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia.

Aucagne R, Droin N, Paggetti J, Lagrange B, Largeot A, Hammann A, Bataille A, Martin L, Yan KP, Fenaux P, Losson R, Solary E, Bastie JN, Delva L.

J Clin Invest. 2011 Jun;121(6):2361-70. doi: 10.1172/JCI45213. Epub 2011 May 2.


MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia.

Moussay E, Wang K, Cho JH, van Moer K, Pierson S, Paggetti J, Nazarov PV, Palissot V, Hood LE, Berchem G, Galas DJ.

Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6573-8. doi: 10.1073/pnas.1019557108. Epub 2011 Apr 1.


Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34+ cells.

Paggetti J, Largeot A, Aucagne R, Jacquel A, Lagrange B, Yang XJ, Solary E, Bastie JN, Delva L.

Oncogene. 2010 Sep 9;29(36):5019-31. doi: 10.1038/onc.2010.254. Epub 2010 Jun 28.


Colony-stimulating factor-1-induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages.

Jacquel A, Benikhlef N, Paggetti J, Lalaoui N, Guery L, Dufour EK, Ciudad M, Racoeur C, Micheau O, Delva L, Droin N, Solary E.

Blood. 2009 Oct 22;114(17):3633-41. doi: 10.1182/blood-2009-03-208843. Epub 2009 Aug 31.


MOZ/TIF2-induced acute myeloid leukaemia in transgenic fish.

Zhuravleva J, Paggetti J, Martin L, Hammann A, Solary E, Bastie JN, Delva L.

Br J Haematol. 2008 Nov;143(3):378-82. doi: 10.1111/j.1365-2141.2008.07362.x. Epub 2008 Aug 20.


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