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Items: 45

1.

Normal inflammation and regeneration of muscle following injury require osteopontin from both muscle and non-muscle cells.

Wasgewatte Wijesinghe DK, Mackie EJ, Pagel CN.

Skelet Muscle. 2019 Feb 26;9(1):6. doi: 10.1186/s13395-019-0190-5.

2.

Keratinocyte-specific ablation of protease-activated receptor 2 prevents gingival inflammation and bone loss in a mouse model of periodontal disease.

Francis N, Ayodele BA, O'Brien-Simpson NM, Birchmeier W, Pike RN, Pagel CN, Mackie EJ.

Cell Microbiol. 2018 Nov;20(11):e12891. doi: 10.1111/cmi.12891. Epub 2018 Jul 31.

PMID:
30009515
3.

The vacuolar H+ ATPase V0 subunit d2 is associated with chondrocyte hypertrophy and supports chondrocyte differentiation.

Ayodele BA, Mirams M, Pagel CN, Mackie EJ.

Bone Rep. 2017 Aug 18;7:98-107. doi: 10.1016/j.bonr.2017.08.002. eCollection 2017 Dec.

4.

A T cell-specific knockout reveals an important role for protease-activated receptor 2 in lymphocyte development.

Francis N, Every AL, Ayodele BA, Pike RN, Mackie EJ, Pagel CN.

Int J Biochem Cell Biol. 2017 Nov;92:95-103. doi: 10.1016/j.biocel.2017.09.015. Epub 2017 Sep 22.

PMID:
28951199
5.

The antiepileptic medications carbamazepine and phenytoin inhibit native sodium currents in murine osteoblasts.

Petty SJ, Milligan CJ, Todaro M, Richards KL, Kularathna PK, Pagel CN, French CR, Hill-Yardin EL, O'Brien TJ, Wark JD, Mackie EJ, Petrou S.

Epilepsia. 2016 Sep;57(9):1398-405. doi: 10.1111/epi.13474. Epub 2016 Jul 21.

6.

Identification of novel osteochondrosis--Associated genes.

Mirams M, Ayodele BA, Tatarczuch L, Henson FM, Pagel CN, Mackie EJ.

J Orthop Res. 2016 Mar;34(3):404-11. doi: 10.1002/jor.23033. Epub 2015 Sep 8.

7.

Evidence of apoptosis induced by viral protein 2 of chicken anaemia virus.

Kaffashi A, Pagel CN, Noormohammadi AH, Browning GF.

Arch Virol. 2015 Oct;160(10):2557-63. doi: 10.1007/s00705-015-2542-8. Epub 2015 Aug 2.

PMID:
26233670
8.

Tumour progression and cancer-induced pain: a role for protease-activated receptor-2?

Kularathna PK, Pagel CN, Mackie EJ.

Int J Biochem Cell Biol. 2014 Dec;57:149-56. doi: 10.1016/j.biocel.2014.10.026. Epub 2014 Oct 30. Review.

PMID:
25448411
9.

Omega-1 knockdown in Schistosoma mansoni eggs by lentivirus transduction reduces granuloma size in vivo.

Hagen J, Young ND, Every AL, Pagel CN, Schnoeller C, Scheerlinck JP, Gasser RB, Kalinna BH.

Nat Commun. 2014 Nov 17;5:5375. doi: 10.1038/ncomms6375.

10.

Contractile properties of slow and fast skeletal muscles from protease activated receptor-1 null mice.

Sitparan PK, Pagel CN, Pinniger GJ, Yoo HJ, Mackie EJ, Bakker AJ.

Muscle Nerve. 2014 Dec;50(6):991-8. doi: 10.1002/mus.24256. Epub 2014 Oct 30.

PMID:
24692104
11.

Osteopontin, inflammation and myogenesis: influencing regeneration, fibrosis and size of skeletal muscle.

Pagel CN, Wasgewatte Wijesinghe DK, Taghavi Esfandouni N, Mackie EJ.

J Cell Commun Signal. 2014 Jun;8(2):95-103. doi: 10.1007/s12079-013-0217-3. Epub 2013 Dec 8.

12.

Thrombin inhibits osteoclast differentiation through a non-proteolytic mechanism.

Sivagurunathan S, Pagel CN, Loh LH, Wijeyewickrema LC, Pike RN, Mackie EJ.

J Mol Endocrinol. 2013 Apr 23;50(3):347-59. doi: 10.1530/JME-12-0177. Print 2013 Jun.

PMID:
23419317
13.

The ovicidal, larvacidal and adulticidal properties of 5,5'-dimethyl-2,2'-bipyridyl against Drosophila melanogaster.

Van Hiel MB, Breugelmans B, Pagel CN, Williams AK, Varan AK, Burke R, Bowles VM, Batterham P.

PLoS One. 2012;7(11):e49961. doi: 10.1371/journal.pone.0049961. Epub 2012 Nov 20.

14.

Osteopontin deficiency delays inflammatory infiltration and the onset of muscle regeneration in a mouse model of muscle injury.

Uaesoontrachoon K, Wasgewatte Wijesinghe DK, Mackie EJ, Pagel CN.

Dis Model Mech. 2013 Jan;6(1):197-205. doi: 10.1242/dmm.009993. Epub 2012 Aug 23.

15.

Evaluation of antibodies directed against human protease-activated receptor-2.

Adams MN, Pagel CN, Mackie EJ, Hooper JD.

Naunyn Schmiedebergs Arch Pharmacol. 2012 Sep;385(9):861-73. doi: 10.1007/s00210-012-0783-6. Epub 2012 Jul 31.

PMID:
22842724
16.

Proteinase-activated receptor-2 is required for normal osteoblast and osteoclast differentiation during skeletal growth and repair.

Georgy SR, Pagel CN, Ghasem-Zadeh A, Zebaze RM, Pike RN, Sims NA, Mackie EJ.

Bone. 2012 Mar;50(3):704-12. doi: 10.1016/j.bone.2011.11.023. Epub 2011 Dec 7.

PMID:
22173052
17.

Identification of light and dark hypertrophic chondrocytes in mouse and rat chondrocyte pellet cultures.

Chen KS, Tatarczuch L, Ahmed Y, Huang HH, Mirams M, Pagel CN, Mackie EJ.

Tissue Cell. 2010 Apr;42(2):121-8. doi: 10.1016/j.tice.2010.02.003. Epub 2010 Mar 19.

PMID:
20303561
18.

Periostin expression distinguishes between light and dark hypertrophic chondrocytes.

Chen KS, Tatarczuch L, Mirams M, Ahmed YA, Pagel CN, Mackie EJ.

Int J Biochem Cell Biol. 2010 Jun;42(6):880-9. doi: 10.1016/j.biocel.2010.01.018. Epub 2010 Jan 18.

PMID:
20083223
19.

Protease-activated receptor 2 has pivotal roles in cellular mechanisms involved in experimental periodontitis.

Wong DM, Tam V, Lam R, Walsh KA, Tatarczuch L, Pagel CN, Reynolds EC, O'Brien-Simpson NM, Mackie EJ, Pike RN.

Infect Immun. 2010 Feb;78(2):629-38. doi: 10.1128/IAI.01019-09. Epub 2009 Nov 23.

20.

Proteinase-activated receptor-2 (PAR2) and mouse osteoblasts: regulation of cell function and lack of specificity of PAR2-activating peptides.

Georgy SR, Pagel CN, Wong DM, Sivagurunathan S, Loh LH, Myers DE, Hollenberg MD, Pike RN, Mackie EJ.

Clin Exp Pharmacol Physiol. 2010 Mar;37(3):328-36. doi: 10.1111/j.1440-1681.2009.05294.x. Epub 2009 Sep 21.

PMID:
19769607
21.

Protease-activated receptor-1 down-regulates the murine inflammatory and humoral response to Helicobacter pylori.

Wee JL, Chionh YT, Ng GZ, Harbour SN, Allison C, Pagel CN, Mackie EJ, Mitchell HM, Ferrero RL, Sutton P.

Gastroenterology. 2010 Feb;138(2):573-82. doi: 10.1053/j.gastro.2009.08.043. Epub 2009 Aug 23.

PMID:
19706295
22.

Thrombin-stimulated growth factor and cytokine expression in osteoblasts is mediated by protease-activated receptor-1 and prostanoids.

Pagel CN, Song SJ, Loh LH, Tudor EM, Murray-Rust TA, Pike RN, Mackie EJ.

Bone. 2009 May;44(5):813-21. doi: 10.1016/j.bone.2008.12.031. Epub 2009 Jan 15.

PMID:
19442625
23.

High molecular weight gingipains from Porphyromonas gingivalis induce cytokine responses from human macrophage-like cells via a nonproteolytic mechanism.

Fitzpatrick RE, Aprico A, Wijeyewickrema LC, Pagel CN, Wong DM, Potempa J, Mackie EJ, Pike RN.

J Innate Immun. 2009;1(2):109-17. doi: 10.1159/000181145. Epub 2008 Dec 2.

24.

Altered gene expression in early osteochondrosis lesions.

Mirams M, Tatarczuch L, Ahmed YA, Pagel CN, Jeffcott LB, Davies HM, Mackie EJ.

J Orthop Res. 2009 Apr;27(4):452-7. doi: 10.1002/jor.20761.

25.

The gingipains from Porphyromonas gingivalis do not directly induce osteoclast differentiation in primary mouse bone marrow cultures.

Fitzpatrick RE, Campbell PD, Sivagurunathan S, Pagel CN, Potempa J, Mackie EJ, Pike RN.

J Periodontal Res. 2009 Aug;44(4):565-7. doi: 10.1111/j.1600-0765.2008.01151.x. Epub 2008 Aug 19.

PMID:
18717779
26.

Osteopontin and skeletal muscle myoblasts: association with muscle regeneration and regulation of myoblast function in vitro.

Uaesoontrachoon K, Yoo HJ, Tudor EM, Pike RN, Mackie EJ, Pagel CN.

Int J Biochem Cell Biol. 2008;40(10):2303-14. doi: 10.1016/j.biocel.2008.03.020. Epub 2008 Apr 6.

PMID:
18490187
27.

Protease-activated receptors in the musculoskeletal system.

Mackie EJ, Loh LH, Sivagurunathan S, Uaesoontrachoon K, Yoo HJ, Wong D, Georgy SR, Pagel CN.

Int J Biochem Cell Biol. 2008;40(6-7):1169-84. doi: 10.1016/j.biocel.2007.12.003. Epub 2007 Dec 23. Review.

PMID:
18243039
28.

Hypertrophy and physiological death of equine chondrocytes in vitro.

Ahmed YA, Tatarczuch L, Pagel CN, Davies HM, Mirams M, Mackie EJ.

Equine Vet J. 2007 Nov;39(6):546-52.

PMID:
18065314
29.

Myoblasts isolated from hypertrophy-responsive callipyge muscles show altered growth rates and increased resistance to serum deprivation-induced apoptosis.

Lavulo LT, Uaesoontrachoon K, Mirams M, White JD, Cockett NE, Mackie EJ, Pagel CN.

Cells Tissues Organs. 2008;187(2):141-51. Epub 2007 Oct 23.

PMID:
17957094
30.

Physiological death of hypertrophic chondrocytes.

Ahmed YA, Tatarczuch L, Pagel CN, Davies HM, Mirams M, Mackie EJ.

Osteoarthritis Cartilage. 2007 May;15(5):575-86. Epub 2006 Dec 13.

31.

Functional responses of bone cells to thrombin.

Pagel CN, Sivagurunathan S, Loh LH, Tudor EM, Pike RN, Mackie EJ.

Biol Chem. 2006 Aug;387(8):1037-41. Review.

PMID:
16895473
32.

Thrombin is a pro-fibrotic factor for rat renal fibroblasts in vitro.

Hewitson TD, Martic M, Kelynack KJ, Pagel CN, Mackie EJ, Becker GJ.

Nephron Exp Nephrol. 2005;101(2):e42-9. Epub 2005 Jun 7.

PMID:
15942256
33.

The role of protease-activated receptor-1 in bone healing.

Song SJ, Pagel CN, Campbell TM, Pike RN, Mackie EJ.

Am J Pathol. 2005 Mar;166(3):857-68.

34.

Studies on the receptors mediating responses of osteoblasts to thrombin.

Song SJ, Pagel CN, Pike RN, Mackie EJ.

Int J Biochem Cell Biol. 2005 Jan;37(1):206-13.

PMID:
15381162
35.

Inhibition of osteoblast apoptosis by thrombin.

Pagel CN, de Niese MR, Abraham LA, Chinni C, Song SJ, Pike RN, Mackie EJ.

Bone. 2003 Oct;33(4):733-43. Erratum in: Bone. 2004 Jul;35(1):343.

PMID:
14555279
36.

Protease-activated receptors: a means of converting extracellular proteolysis into intracellular signals.

Mackie EJ, Pagel CN, Smith R, de Niese MR, Song SJ, Pike RN.

IUBMB Life. 2002 Jun;53(6):277-81. Review.

37.

Myogenic cell proliferation and generation of a reversible tumorigenic phenotype are triggered by preirradiation of the recipient site.

Morgan JE, Gross JG, Pagel CN, Beauchamp JR, Fassati A, Thrasher AJ, Di Santo JP, Fisher IB, Shiwen X, Abraham DJ, Partridge TA.

J Cell Biol. 2002 May 13;157(4):693-702. Epub 2002 May 13.

38.

Thymic myoid cells as a source of cells for myoblast transfer.

Pagel CN, Morgan JE, Gross JG, Partridge TA.

Cell Transplant. 2000 Jul-Aug;9(4):531-8.

PMID:
11038069
39.

Covert persistence of mdx mouse myopathy is revealed by acute and chronic effects of irradiation.

Pagel CN, Partridge TA.

J Neurol Sci. 1999 Apr 1;164(2):103-16.

PMID:
10402020
40.
41.

A dual-marker system for quantitative studies of myoblast transplantation in the mouse.

Beauchamp JR, Pagel CN, Partridge TA.

Transplantation. 1997 Jun 27;63(12):1794-7.

PMID:
9210506
42.

Myoblast transfer and gene therapy in muscular dystrophies.

Pagel CN, Morgan JE.

Microsc Res Tech. 1995 Apr 15;30(6):469-79. Review.

PMID:
7599358
43.

Myogenic cell lines derived from transgenic mice carrying a thermolabile T antigen: a model system for the derivation of tissue-specific and mutation-specific cell lines.

Morgan JE, Beauchamp JR, Pagel CN, Peckham M, Ataliotis P, Jat PS, Noble MD, Farmer K, Partridge TA.

Dev Biol. 1994 Apr;162(2):486-98.

PMID:
8150209
44.

Long-term persistence and migration of myogenic cells injected into pre-irradiated muscles of mdx mice.

Morgan JE, Pagel CN, Sherratt T, Partridge TA.

J Neurol Sci. 1993 Apr;115(2):191-200.

PMID:
7683332
45.

Localization of donor nuclei in skeletal muscle grafts by in situ hybridization to a cDNA probe.

Coulton GR, Skynner MJ, Smith T, Pagel CN, Partridge TA.

Histochem J. 1991 Jul;23(7):323-7.

PMID:
1783568

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