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Head-to-Head Comparison among Semi-Quantification Tools of Brain FDG-PET to Aid the Diagnosis of Prodromal Alzheimer's Disease.

Brugnolo A, De Carli F, Pagani M, Morbelli S, Jonsson C, Chincarini A, Frisoni GB, Galluzzi S, Perneczky R, Drzezga A, van Berckel BNM, Ossenkoppele R, Didic M, Guedj E, Arnaldi D, Massa F, Grazzini M, Pardini M, Mecocci P, Dottorini ME, Bauckneht M, Sambuceti G, Nobili F.

J Alzheimers Dis. 2019 Feb 13. doi: 10.3233/JAD-181022. [Epub ahead of print]


Left ventricular hypertrophy in world class elite athletes is associated with signs of improved cardiac autonomic regulation.

Oggionni G, Spataro A, Pelliccia A, Malacarne M, Pagani M, Lucini D.

Eur J Prev Cardiol. 2019 Feb 12:2047487319830534. doi: 10.1177/2047487319830534. [Epub ahead of print]


Brain Glucose Metabolism Heterogeneity in Idiopathic REM Sleep Behavior Disorder and in Parkinson's Disease.

Arnaldi D, Meles SK, Giuliani A, Morbelli S, Renken RJ, Janzen A, Mayer G, Jonsson C, Oertel WH, Nobili F, Leenders KL, Pagani M; REMPET Study Group .

J Parkinsons Dis. 2019;9(1):229-239. doi: 10.3233/JPD-181468.


Dorsal Horn Gastrin-Releasing Peptide Expressing Neurons Transmit Spinal Itch But Not Pain Signals.

Albisetti GW, Pagani M, Platonova E, Hösli L, Johannssen HC, Fritschy JM, Wildner H, Zeilhofer HU.

J Neurosci. 2019 Jan 17. pii: 2559-18. doi: 10.1523/JNEUROSCI.2559-18.2019. [Epub ahead of print]


Testing the diagnostic accuracy of [18F]FDG-PET in discriminating spinal- and bulbar-onset amyotrophic lateral sclerosis.

Sala A, Iaccarino L, Fania P, Vanoli EG, Fallanca F, Pagnini C, Cerami C, Calvo A, Canosa A, Pagani M, Chiò A, Cistaro A, Perani D.

Eur J Nucl Med Mol Imaging. 2019 Jan 7. doi: 10.1007/s00259-018-4246-2. [Epub ahead of print]


Plant Frataxin in Metal Metabolism.

Gomez-Casati DF, Busi MV, Pagani MA.

Front Plant Sci. 2018 Nov 21;9:1706. doi: 10.3389/fpls.2018.01706. eCollection 2018.


The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.

Ricciardi S, Manfrini N, Alfieri R, Calamita P, Crosti MC, Gallo S, Müller R, Pagani M, Abrignani S, Biffo S.

Cell Metab. 2018 Dec 4;28(6):961. doi: 10.1016/j.cmet.2018.09.010. No abstract available.


Eomesodermin controls a unique differentiation program in human IL-10 and IFN-γ coproducing regulatory T cells.

Gruarin P, Maglie S, De Simone M, Häringer B, Vasco C, Ranzani V, Bosotti R, Noddings JS, Larghi P, Facciotti F, Sarnicola ML, Martinovic M, Crosti M, Moro M, Rossi RL, Bernardo ME, Caprioli F, Locatelli F, Rossetti G, Abrignani S, Pagani M, Geginat J.

Eur J Immunol. 2019 Jan;49(1):96-111. doi: 10.1002/eji.201847722. Epub 2018 Nov 29.


Accuracy and generalization capability of an automatic method for the detection of typical brain hypometabolism in prodromal Alzheimer disease.

De Carli F, Nobili F, Pagani M, Bauckneht M, Massa F, Grazzini M, Jonsson C, Peira E, Morbelli S, Arnaldi D; Alzheimer’s Disease Neuroimaging Initiative.

Eur J Nucl Med Mol Imaging. 2019 Feb;46(2):334-347. doi: 10.1007/s00259-018-4197-7. Epub 2018 Oct 31.


Effect of processing conditions on water mobility and cooking quality of gluten-free pasta. A Magnetic Resonance Imaging study.

Marti A, Ragg EM, Pagani MA.

Food Chem. 2018 Nov 15;266:17-23. doi: 10.1016/j.foodchem.2018.05.057. Epub 2018 May 22.


Ferrochelatase activity of plant frataxin.

Armas AM, Balparda M, Terenzi A, Busi MV, Pagani MA, Gomez-Casati DF.

Biochimie. 2019 Jan;156:118-122. doi: 10.1016/j.biochi.2018.10.009. Epub 2018 Oct 18.


Role of Skin Tests in the Diagnosis of Immediate Hypersensitivity Reactions to Taxanes: Results of a Multicenter Study.

Pagani M, Bavbek S, Dursun AB, Bonadonna P, Caralli M, Cernadas J, Cortellini G, Costantino MT, Gelincik A, Lucchini G, Castells M.

J Allergy Clin Immunol Pract. 2018 Oct 5. pii: S2213-2198(18)30595-6. doi: 10.1016/j.jaip.2018.09.018. [Epub ahead of print]


Correlation between Apolipoprotein E genotype and brain metabolism in amyotrophic lateral sclerosis.

Canosa A, Pagani M, Brunetti M, Barberis M, Iazzolino B, Ilardi A, Cammarosano S, Manera U, Moglia C, Calvo A, Cistaro A, Chiò A.

Eur J Neurol. 2019 Feb;26(2):306-312. doi: 10.1111/ene.13812. Epub 2018 Oct 24.


The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.

Ricciardi S, Manfrini N, Alfieri R, Calamita P, Crosti MC, Gallo S, Müller R, Pagani M, Abrignani S, Biffo S.

Cell Metab. 2018 Dec 4;28(6):895-906.e5. doi: 10.1016/j.cmet.2018.08.009. Epub 2018 Sep 6. Erratum in: Cell Metab. 2018 Dec 4;28(6):961.


How Does Eye Movement Desensitization and Reprocessing Therapy Work? A Systematic Review on Suggested Mechanisms of Action.

Landin-Romero R, Moreno-Alcazar A, Pagani M, Amann BL.

Front Psychol. 2018 Aug 13;9:1395. doi: 10.3389/fpsyg.2018.01395. eCollection 2018.


Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors.

Ralvenius WT, Neumann E, Pagani M, Acuña MA, Wildner H, Benke D, Fischer N, Rostaher A, Schwager S, Detmar M, Frauenknecht K, Aguzzi A, Hubbs JL, Rudolph U, Favrot C, Zeilhofer HU.

Nat Commun. 2018 Aug 13;9(1):3230. doi: 10.1038/s41467-018-05709-0.


Single Cell T Cell Receptor Sequencing: Techniques and Future Challenges.

De Simone M, Rossetti G, Pagani M.

Front Immunol. 2018 Jul 18;9:1638. doi: 10.3389/fimmu.2018.01638. eCollection 2018. Review.


Benchmarking Heart Rate Variability to Overcome Sex-Related Bias.

Pagani M, Sala R, Malacarne M, Lucini D.

Adv Exp Med Biol. 2018;1065:191-205. doi: 10.1007/978-3-319-77932-4_13.


A high-throughput method to identify trans-activation domains within transcription factor sequences.

Arnold CD, Nemčko F, Woodfin AR, Wienerroither S, Vlasova A, Schleiffer A, Pagani M, Rath M, Stark A.

EMBO J. 2018 Aug 15;37(16). pii: e98896. doi: 10.15252/embj.201798896. Epub 2018 Jul 13.


On the Relevance of Computing a Local Version of Sample Entropy in Cardiovascular Control Analysis.

Porta A, Bari V, De Maria B, Cairo B, Vaini E, Malacarne M, Pagani M, Lucini D.

IEEE Trans Biomed Eng. 2018 Jul 3. doi: 10.1109/TBME.2018.2852713. [Epub ahead of print]


Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth.

Pacella I, Procaccini C, Focaccetti C, Miacci S, Timperi E, Faicchia D, Severa M, Rizzo F, Coccia EM, Bonacina F, Mitro N, Norata GD, Rossetti G, Ranzani V, Pagani M, Giorda E, Wei Y, Matarese G, Barnaba V, Piconese S.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6546-E6555. doi: 10.1073/pnas.1720113115. Epub 2018 Jun 25.


Pharmacological Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice.

Pucilowska J, Vithayathil J, Pagani M, Kelly C, Karlo JC, Robol C, Morella I, Gozzi A, Brambilla R, Landreth GE.

J Neurosci. 2018 Jul 25;38(30):6640-6652. doi: 10.1523/JNEUROSCI.0515-17.2018. Epub 2018 Jun 22.


Peripheral Resistance Baroreflex During Incremental Bicycle Ergometer Exercise: Characterization and Correlation With Cardiac Baroreflex.

Porta A, Bari V, Maria B, Cairo B, Vaini E, Malacarne M, Pagani M, Lucini D.

Front Physiol. 2018 Jun 5;9:688. doi: 10.3389/fphys.2018.00688. eCollection 2018.


Dealing With the Aftermath of Mass Disasters: A Field Study on the Application of EMDR Integrative Group Treatment Protocol With Child Survivors of the 2016 Italy Earthquakes.

Trentini C, Lauriola M, Giuliani A, Maslovaric G, Tambelli R, Fernandez I, Pagani M.

Front Psychol. 2018 Jun 4;9:862. doi: 10.3389/fpsyg.2018.00862. eCollection 2018.


Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity.

Wang D, Quiros J, Mahuron K, Pai CC, Ranzani V, Young A, Silveria S, Harwin T, Abnousian A, Pagani M, Rosenblum MD, Van Gool F, Fong L, Bluestone JA, DuPage M.

Cell Rep. 2018 Jun 12;23(11):3262-3274. doi: 10.1016/j.celrep.2018.05.050.


Multicenter validation of [18F]-FDG PET and support-vector machine discriminant analysis in automatically classifying patients with amyotrophic lateral sclerosis versus controls.

D'hulst L, Van Weehaeghe D, Chiò A, Calvo A, Moglia C, Canosa A, Cistaro A, Willekens SM, De Vocht J, Van Damme P, Pagani M, Van Laere K.

Amyotroph Lateral Scler Frontotemporal Degener. 2018 Jun 4:1-8. doi: 10.1080/21678421.2018.1476548. [Epub ahead of print]


Autonomic Differentiation Map: A Novel Statistical Tool for Interpretation of Heart Rate Variability.

Lucini D, Solaro N, Pagani M.

Front Physiol. 2018 Apr 23;9:401. doi: 10.3389/fphys.2018.00401. eCollection 2018.


Autism-associated 16p11.2 microdeletion impairs prefrontal functional connectivity in mouse and human.

Bertero A, Liska A, Pagani M, Parolisi R, Masferrer ME, Gritti M, Pedrazzoli M, Galbusera A, Sarica A, Cerasa A, Buffelli M, Tonini R, Buffo A, Gross C, Pasqualetti M, Gozzi A.

Brain. 2018 Jul 1;141(7):2055-2065. doi: 10.1093/brain/awy111.


Clinical utility of FDG-PET in amyotrophic lateral sclerosis and Huntington's disease.

Agosta F, Altomare D, Festari C, Orini S, Gandolfo F, Boccardi M, Arbizu J, Bouwman F, Drzezga A, Nestor P, Nobili F, Walker Z, Pagani M; EANM-EAN Task Force for the Prescription of FDG-PET for Dementing Neurodegenerative Disorders.

Eur J Nucl Med Mol Imaging. 2018 Jul;45(9):1546-1556. doi: 10.1007/s00259-018-4033-0. Epub 2018 May 1. Review.


Metabolic and Electrophysiological Changes Associated to Clinical Improvement in Two Severely Traumatized Subjects Treated With EMDR-A Pilot Study.

Pagani M, Castelnuovo G, Daverio A, La Porta P, Monaco L, Ferrentino F, Chiaravalloti A, Fernandez I, Di Lorenzo G.

Front Psychol. 2018 Apr 16;9:475. doi: 10.3389/fpsyg.2018.00475. eCollection 2018.


Altered Neocortical Gene Expression, Brain Overgrowth and Functional Over-Connectivity in Chd8 Haploinsufficient Mice.

Suetterlin P, Hurley S, Mohan C, Riegman KLH, Pagani M, Caruso A, Ellegood J, Galbusera A, Crespo-Enriquez I, Michetti C, Yee Y, Ellingford R, Brock O, Delogu A, Francis-West P, Lerch JP, Scattoni ML, Gozzi A, Fernandes C, Basson MA.

Cereb Cortex. 2018 Jun 1;28(6):2192-2206. doi: 10.1093/cercor/bhy058.


Metabolic correlates of reserve and resilience in MCI due to Alzheimer's Disease (AD).

Bauckneht M, Chincarini A, Piva R, Arnaldi D, Girtler N, Massa F, Pardini M, Grazzini M, Efeturk H, Pagani M, Sambuceti G, Nobili F, Morbelli S.

Alzheimers Res Ther. 2018 Apr 3;10(1):35. doi: 10.1186/s13195-018-0366-y.


Comparison of Eye Movement Desensitization Reprocessing and Cognitive Behavioral Therapy as Adjunctive Treatments for Recurrent Depression: The European Depression EMDR Network (EDEN) Randomized Controlled Trial.

Ostacoli L, Carletto S, Cavallo M, Baldomir-Gago P, Di Lorenzo G, Fernandez I, Hase M, Justo-Alonso A, Lehnung M, Migliaretti G, Oliva F, Pagani M, Recarey-Eiris S, Torta R, Tumani V, Gonzalez-Vazquez AI, Hofmann A.

Front Psychol. 2018 Feb 13;9:74. doi: 10.3389/fpsyg.2018.00074. eCollection 2018.


Quinoa bitterness: causes and solutions for improving product acceptability.

Suárez-Estrella D, Torri L, Pagani MA, Marti A.

J Sci Food Agric. 2018 Aug;98(11):4033-4041. doi: 10.1002/jsfa.8980. Epub 2018 Apr 30. Review.


The Metabolic Pattern of Idiopathic REM Sleep Behavior Disorder Reflects Early-Stage Parkinson Disease.

Meles SK, Renken RJ, Janzen A, Vadasz D, Pagani M, Arnaldi D, Morbelli S, Nobili F, Mayer G, Leenders KL, Oertel WH; REMPET Study Group.

J Nucl Med. 2018 Sep;59(9):1437-1444. doi: 10.2967/jnumed.117.202242. Epub 2018 Feb 23.


Can the use of a single integrated unitary autonomic index provide early clues for eventual eligibility for olympic games?

Lucini D, Sala R, Spataro A, Malacarne M, Benzi M, Tamorri S, Pagani M.

Eur J Appl Physiol. 2018 May;118(5):919-926. doi: 10.1007/s00421-018-3822-2. Epub 2018 Feb 15.


EMDR as Add-On Treatment for Psychiatric and Traumatic Symptoms in Patients with Substance Use Disorder.

Carletto S, Oliva F, Barnato M, Antonelli T, Cardia A, Mazzaferro P, Raho C, Ostacoli L, Fernandez I, Pagani M.

Front Psychol. 2018 Jan 11;8:2333. doi: 10.3389/fpsyg.2017.02333. eCollection 2017.


Intestinal IFN-γ-producing type 1 regulatory T cells coexpress CCR5 and programmed cell death protein 1 and downregulate IL-10 in the inflamed guts of patients with inflammatory bowel disease.

Alfen JS, Larghi P, Facciotti F, Gagliani N, Bosotti R, Paroni M, Maglie S, Gruarin P, Vasco CM, Ranzani V, Frusteri C, Iseppon A, Moro M, Crosti MC, Gatti S, Pagani M, Caprioli F, Abrignani S, Flavell RA, Geginat J.

J Allergy Clin Immunol. 2018 Nov;142(5):1537-1547.e8. doi: 10.1016/j.jaci.2017.12.984. Epub 2018 Jan 31.


Lack of Methyl-CpG Binding Protein 2 (MeCP2) Affects Cell Fate Refinement During Embryonic Cortical Development.

Cobolli Gigli C, Scaramuzza L, De Simone M, Rossi RL, Pozzi D, Pagani M, Landsberger N, Bedogni F.

Cereb Cortex. 2018 May 1;28(5):1846-1856. doi: 10.1093/cercor/bhx360.


Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes.

Conforti P, Besusso D, Bocchi VD, Faedo A, Cesana E, Rossetti G, Ranzani V, Svendsen CN, Thompson LM, Toselli M, Biella G, Pagani M, Cattaneo E.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E762-E771. doi: 10.1073/pnas.1715865115. Epub 2018 Jan 8. Erratum in: Proc Natl Acad Sci U S A. 2018 Feb 20;:.


Observational, multicentre study on the epidemiology of haemoptysis.

Mondoni M, Carlucci P, Job S, Parazzini EM, Cipolla G, Pagani M, Tursi F, Negri L, Fois A, Canu S, Arcadu A, Pirina P, Bonifazi M, Gasparini S, Marani S, Comel AC, Ravenna F, Dore S, Alfano F, Sferrazza Papa GF, Di Marco F, Centanni S, Sotgiu G.

Eur Respir J. 2018 Jan 4;51(1). pii: 1701813. doi: 10.1183/13993003.01813-2017. Print 2018 Jan. No abstract available.


Copper redox chemistry of plant frataxins.

Sánchez M, Palacios Ò, Buchensky C, Sabio L, Gomez-Casati DF, Pagani MA, Capdevila M, Atrian S, Dominguez-Vera JM.

J Inorg Biochem. 2018 Mar;180:135-140. doi: 10.1016/j.jinorgbio.2017.11.020. Epub 2017 Nov 27.


Anaphylactic Reactions After Discontinuation of Hymenoptera Venom Immunotherapy: A Clonal Mast Cell Disorder Should Be Suspected.

Bonadonna P, Zanotti R, Pagani M, Bonifacio M, Scaffidi L, Olivieri E, Franchini M, Reccardini F, Costantino MT, Roncallo C, Mauro M, Boni E, Rizzini FL, Bilò MB, Marcarelli AR, Passalacqua G.

J Allergy Clin Immunol Pract. 2018 Jul - Aug;6(4):1368-1372. doi: 10.1016/j.jaip.2017.11.025. Epub 2017 Dec 16.


Resolving systematic errors in widely used enhancer activity assays in human cells.

Muerdter F, Boryń ŁM, Woodfin AR, Neumayr C, Rath M, Zabidi MA, Pagani M, Haberle V, Kazmar T, Catarino RR, Schernhuber K, Arnold CD, Stark A.

Nat Methods. 2018 Feb;15(2):141-149. doi: 10.1038/nmeth.4534. Epub 2017 Dec 11.


The Role of Slow Wave Sleep in Memory Pathophysiology: Focus on Post-traumatic Stress Disorder and Eye Movement Desensitization and Reprocessing.

Carletto S, Borsato T, Pagani M.

Front Psychol. 2017 Nov 22;8:2050. doi: 10.3389/fpsyg.2017.02050. eCollection 2017. No abstract available.


Understanding the influence of buckwheat bran on wheat dough baking performance: Mechanistic insights from molecular and material science approaches.

Zanoletti M, Marti A, Marengo M, Iametti S, Pagani MA, Renzetti S.

Food Res Int. 2017 Dec;102:728-737. doi: 10.1016/j.foodres.2017.09.052. Epub 2017 Sep 20.


Eye Movement Desensitization and Reprocessing and Slow Wave Sleep: A Putative Mechanism of Action.

Pagani M, Amann BL, Landin-Romero R, Carletto S.

Front Psychol. 2017 Nov 7;8:1935. doi: 10.3389/fpsyg.2017.01935. eCollection 2017.


Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells.

Ripamonti A, Provasi E, Lorenzo M, De Simone M, Ranzani V, Vangelisti S, Curti S, Bonnal RJP, Pignataro L, Torretta S, Geginat J, Rossetti G, Pagani M, Abrignani S.

Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):12797-12802. doi: 10.1073/pnas.1705364114. Epub 2017 Nov 13.


Characterization of Whole Grain Pasta: Integrating Physical, Chemical, Molecular, and Instrumental Sensory Approaches.

Marti A, Cattaneo S, Benedetti S, Buratti S, Abbasi Parizad P, Masotti F, Iametti S, Pagani MA.

J Food Sci. 2017 Nov;82(11):2583-2590. doi: 10.1111/1750-3841.13938.


The detection of interval colorectal cancers following screening by fecal immunochemical test may predict worse outcomes and prompt ethical concerns: a 6-year population-based cohort study in a full district.

Asteria CR, Lucchini G, Guarda L, Ricci P, Pagani M, Boccia L.

Eur J Cancer Prev. 2019 Jan;28(1):17-26. doi: 10.1097/CEJ.0000000000000416.


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