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Items: 11


New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors.

Byrne DP, Li Y, Ramakrishnan K, Barsukov IL, Yates EA, Eyers CE, Papy-Garcia D, Chantepie S, Pagadala V, Liu J, Wells C, Drewry DH, Zuercher WJ, Berry NG, Fernig DG, Eyers PA.

Biochem J. 2018 Aug 14;475(15):2417-2433. doi: 10.1042/BCJ20180265.


Chemoenzymatic synthesis of heparan sulfate and heparin oligosaccharides and NMR analysis: paving the way to a diverse library for glycobiologists.

Zhang X, Pagadala V, Jester HM, Lim AM, Pham TQ, Goulas AMP, Liu J, Linhardt RJ.

Chem Sci. 2017 Dec 1;8(12):7932-7940. doi: 10.1039/c7sc03541a. Epub 2017 Sep 21.


Synthetic oligosaccharides can replace animal-sourced low-molecular weight heparins.

Xu Y, Chandarajoti K, Zhang X, Pagadala V, Dou W, Hoppensteadt DM, Sparkenbaugh EM, Cooley B, Daily S, Key NS, Severynse-Stevens D, Fareed J, Linhardt RJ, Pawlinski R, Liu J.

Sci Transl Med. 2017 Sep 6;9(406). pii: eaan5954. doi: 10.1126/scitranslmed.aan5954.


The TRPM1 channel in ON-bipolar cells is gated by both the α and the βγ subunits of the G-protein Go.

Xu Y, Orlandi C, Cao Y, Yang S, Choi CI, Pagadala V, Birnbaumer L, Martemyanov KA, Vardi N.

Sci Rep. 2016 Feb 17;6:20940. doi: 10.1038/srep20940.


Role of Deacetylase Activity of N-Deacetylase/N-Sulfotransferase 1 in Forming N-Sulfated Domain in Heparan Sulfate.

Dou W, Xu Y, Pagadala V, Pedersen LC, Liu J.

J Biol Chem. 2015 Aug 14;290(33):20427-37. doi: 10.1074/jbc.M115.664409. Epub 2015 Jun 24.


Understanding structure, function, and mutations in the mitochondrial ATP synthase.

Xu T, Pagadala V, Mueller DM.

Microb Cell. 2015 Apr 1;2(4):105-125.


Comparison between single-molecule and X-ray crystallography data on yeast F1-ATPase.

Steel BC, Nord AL, Wang Y, Pagadala V, Mueller DM, Berry RM.

Sci Rep. 2015 Mar 10;5:8773. doi: 10.1038/srep08773.


A minimal set of tissue-specific hypomethylated CpGs constitute epigenetic signatures of developmental programming.

Colaneri A, Wang T, Pagadala V, Kittur J, Staffa NG Jr, Peddada SD, Isganaitis E, Patti ME, Birnbaumer L.

PLoS One. 2013 Sep 12;8(9):e72670. doi: 10.1371/journal.pone.0072670. eCollection 2013.


Structure of the c(10) ring of the yeast mitochondrial ATP synthase in the open conformation.

Symersky J, Pagadala V, Osowski D, Krah A, Meier T, Faraldo-Gómez JD, Mueller DM.

Nat Struct Mol Biol. 2012 Apr 15;19(5):485-91, S1. doi: 10.1038/nsmb.2284.


Characterization of the mitochondrial ATP synthase from yeast Saccharomyces cerevisae.

Pagadala V, Vistain L, Symersky J, Mueller DM.

J Bioenerg Biomembr. 2011 Aug;43(4):333-47. doi: 10.1007/s10863-011-9364-5. Epub 2011 Jul 12.


Crystal structures of mutant forms of the yeast F1 ATPase reveal two modes of uncoupling.

Arsenieva D, Symersky J, Wang Y, Pagadala V, Mueller DM.

J Biol Chem. 2010 Nov 19;285(47):36561-9. doi: 10.1074/jbc.M110.174383. Epub 2010 Sep 14.

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