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Items: 17

1.

Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II.

Schneider T, Kruse T, Wimmer R, Wiedemann I, Sass V, Pag U, Jansen A, Nielsen AK, Mygind PH, Raventós DS, Neve S, Ravn B, Bonvin AM, De Maria L, Andersen AS, Gammelgaard LK, Sahl HG, Kristensen HH.

Science. 2010 May 28;328(5982):1168-72. doi: 10.1126/science.1185723.

2.

Artificial beta-defensin based on a minimal defensin template.

Antcheva N, Morgera F, Creatti L, Vaccari L, Pag U, Pacor S, Shai Y, Sahl HG, Tossi A.

Biochem J. 2009 Jul 15;421(3):435-47. doi: 10.1042/BJ20082242.

PMID:
19453294
3.

Mode of action of human beta-defensin 3 against Staphylococcus aureus and transcriptional analysis of responses to defensin challenge.

Sass V, Pag U, Tossi A, Bierbaum G, Sahl HG.

Int J Med Microbiol. 2008 Oct;298(7-8):619-33. doi: 10.1016/j.ijmm.2008.01.011. Epub 2008 May 1.

PMID:
18455476
4.

Analysis of in vitro activities and modes of action of synthetic antimicrobial peptides derived from an alpha-helical 'sequence template'.

Pag U, Oedenkoven M, Sass V, Shai Y, Shamova O, Antcheva N, Tossi A, Sahl HG.

J Antimicrob Chemother. 2008 Feb;61(2):341-52. doi: 10.1093/jac/dkm479. Epub 2008 Jan 3.

PMID:
18174202
5.

Tuning the biological properties of amphipathic alpha-helical antimicrobial peptides: rational use of minimal amino acid substitutions.

Zelezetsky I, Pag U, Sahl HG, Tossi A.

Peptides. 2005 Dec;26(12):2368-76. Epub 2005 Jun 6.

PMID:
15939509
6.
7.

Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin.

Zelezetsky I, Pag U, Antcheva N, Sahl HG, Tossi A.

Arch Biochem Biophys. 2005 Feb 15;434(2):358-64.

PMID:
15639237
8.

Mammalian defensins: structures and mechanism of antibiotic activity.

Sahl HG, Pag U, Bonness S, Wagner S, Antcheva N, Tossi A.

J Leukoc Biol. 2005 Apr;77(4):466-75. Epub 2004 Dec 6. Review.

PMID:
15582982
9.

Mersacidin eradicates methicillin-resistant Staphylococcus aureus (MRSA) in a mouse rhinitis model.

Kruszewska D, Sahl HG, Bierbaum G, Pag U, Hynes SO, Ljungh A.

J Antimicrob Chemother. 2004 Sep;54(3):648-53. Epub 2004 Jul 28.

PMID:
15282239
10.

Localization and functional analysis of PepI, the immunity peptide of Pep5-producing Staphylococcus epidermidis strain 5.

Hoffmann A, Schneider T, Pag U, Sahl HG.

Appl Environ Microbiol. 2004 Jun;70(6):3263-71.

11.

In vitro activity and mode of action of diastereomeric antimicrobial peptides against bacterial clinical isolates.

Pag U, Oedenkoven M, Papo N, Oren Z, Shai Y, Sahl HG.

J Antimicrob Chemother. 2004 Feb;53(2):230-9. Epub 2004 Jan 16.

PMID:
14729742
12.

Combination of antibiotic mechanisms in lantibiotics.

Hoffmann A, Pag U, Wiedemann I, Sahl HG.

Farmaco. 2002 Aug;57(8):685-91. Review.

PMID:
12361237
13.

The consequence of sequence alteration of an amphipathic alpha-helical antimicrobial peptide and its diastereomers.

Papo N, Oren Z, Pag U, Sahl HG, Shai Y.

J Biol Chem. 2002 Sep 13;277(37):33913-21. Epub 2002 Jul 10.

14.

Multiple activities in lantibiotics--models for the design of novel antibiotics?

Pag U, Sahl HG.

Curr Pharm Des. 2002;8(9):815-33.

PMID:
11945173
15.

Molecular analysis of expression of the lantibiotic pep5 immunity phenotype.

Pag U, Heidrich C, Bierbaum G, Sahl HG.

Appl Environ Microbiol. 1999 Feb;65(2):591-8.

16.

Isolation, characterization, and heterologous expression of the novel lantibiotic epicidin 280 and analysis of its biosynthetic gene cluster.

Heidrich C, Pag U, Josten M, Metzger J, Jack RW, Bierbaum G, Jung G, Sahl HG.

Appl Environ Microbiol. 1998 Sep;64(9):3140-6.

17.

Effect of leader peptide mutations on biosynthesis of the lantibiotic Pep5.

Neis S, Bierbaum G, Josten M, Pag U, Kempter C, Jung G, Sahl HG.

FEMS Microbiol Lett. 1997 Apr 15;149(2):249-55.

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