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Items: 16

1.

T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4Ig but is successfully treated by interleukin-17 neutralization.

Koenders MI, Marijnissen RJ, Joosten LA, Abdollahi-Roodsaz S, Di Padova FE, van de Loo FA, Dulos J, van den Berg WB, Boots AM.

Arthritis Rheum. 2012 Jun;64(6):1762-70. doi: 10.1002/art.34352. Epub 2011 Dec 27.

2.

Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice.

Koenders MI, Devesa I, Marijnissen RJ, Abdollahi-Roodsaz S, Boots AM, Walgreen B, di Padova FE, Nicklin MJ, Joosten LA, van den Berg WB.

Arthritis Rheum. 2008 Nov;58(11):3461-70. doi: 10.1002/art.23957.

3.

Interleukin-17 acts independently of TNF-alpha under arthritic conditions.

Koenders MI, Lubberts E, van de Loo FA, Oppers-Walgreen B, van den Bersselaar L, Helsen MM, Kolls JK, Di Padova FE, Joosten LA, van den Berg WB.

J Immunol. 2006 May 15;176(10):6262-9.

4.

Pyrazoloheteroaryls: novel p38alpha MAP kinase inhibiting scaffolds with oral activity.

Revesz L, Blum E, Di Padova FE, Buhl T, Feifel R, Gram H, Hiestand P, Manning U, Neumann U, Rucklin G.

Bioorg Med Chem Lett. 2006 Jan 15;16(2):262-6. Epub 2005 Oct 24.

PMID:
16249085
5.

Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1.

Koenders MI, Lubberts E, Oppers-Walgreen B, van den Bersselaar L, Helsen MM, Di Padova FE, Boots AM, Gram H, Joosten LA, van den Berg WB.

Am J Pathol. 2005 Jul;167(1):141-9.

6.

SAR of benzoylpyridines and benzophenones as p38alpha MAP kinase inhibitors with oral activity.

Revesz L, Blum E, Di Padova FE, Buhl T, Feifel R, Gram H, Hiestand P, Manning U, Rucklin G.

Bioorg Med Chem Lett. 2004 Jul 5;14(13):3601-5.

PMID:
15177483
7.

Novel p38 inhibitors with potent oral efficacy in several models of rheumatoid arthritis.

Revesz L, Blum E, Di Padova FE, Buhl T, Feifel R, Gram H, Hiestand P, Manning U, Rucklin G.

Bioorg Med Chem Lett. 2004 Jul 5;14(13):3595-9.

PMID:
15177482
8.

Identification of a cross-reactive epitope widely present in lipopolysaccharide from enterobacteria and recognized by the cross-protective monoclonal antibody WN1 222-5.

Muller-Loennies S, Brade L, MacKenzie CR, Di Padova FE, Brade H.

J Biol Chem. 2003 Jul 11;278(28):25618-27. Epub 2003 Apr 25.

9.

SAR of 2,6-diamino-3,5-difluoropyridinyl substituted heterocycles as novel p38MAP kinase inhibitors.

Revesz L, Di Padova FE, Buhl T, Feifel R, Gram H, Hiestand P, Manning U, Wolf R, Zimmerlin AG.

Bioorg Med Chem Lett. 2002 Aug 19;12(16):2109-12.

PMID:
12127515
10.

SAR of 4-hydroxypiperidine and hydroxyalkyl substituted heterocycles as novel p38 map kinase inhibitors.

Revesz L, Di Padova FE, Buhl T, Feifel R, Gram H, Hiestand P, Manning U, Zimmerlin AG.

Bioorg Med Chem Lett. 2000 Jun 5;10(11):1261-4.

PMID:
10866395
11.

Monoclonal antibody to endotoxin attenuates hemorrhage-induced lung injury and mortality in rats.

Bahrami S, Yao YM, Leichtfried G, Redl H, Schlag G, Di Padova FE.

Crit Care Med. 1997 Jun;25(6):1030-6.

PMID:
9201057
12.

Role of repetitive antigen patterns for induction of antibodies against antibodies.

Fehr T, Bachmann MF, Bucher E, Kalinke U, Di Padova FE, Lang AB, Hengartner H, Zinkernagel RM.

J Exp Med. 1997 May 19;185(10):1785-92.

13.

Anti-lipopolysaccharide core antibodies.

Di Padova FE, Mikol V, Barclay GR, Poxton IR, Brade H, Rietschel ET.

Prog Clin Biol Res. 1994;388:85-94. No abstract available.

PMID:
7831378
14.

A broadly cross-protective monoclonal antibody binding to Escherichia coli and Salmonella lipopolysaccharides.

Di Padova FE, Brade H, Barclay GR, Poxton IR, Liehl E, Schuetze E, Kocher HP, Ramsay G, Schreier MH, McClelland DB, et al.

Infect Immun. 1993 Sep;61(9):3863-72.

15.

Pharmacology of cyclosporine (sandimmune). V. Pharmacological effects on immune function: in vitro studies.

Di Padova FE.

Pharmacol Rev. 1990 Sep;41(3):373-405. Review. No abstract available.

PMID:
2185491
16.

Interleukin-6 is produced by bone and modulated by parathyroid hormone.

Feyen JH, Elford P, Di Padova FE, Trechsel U.

J Bone Miner Res. 1989 Aug;4(4):633-8.

PMID:
2816508

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