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Items: 1 to 50 of 67

1.

Human Marfan and Marfan-like Syndrome associated mutations lead to altered trafficking of the Type II TGFβ receptor in Caenorhabditis elegans.

Lin J, Vora M, Kane NS, Gleason RJ, Padgett RW.

PLoS One. 2019 May 9;14(5):e0216628. doi: 10.1371/journal.pone.0216628. eCollection 2019.

2.

Mutagenesis and Imaging Studies of BMP Signaling Mechanisms in C. elegans.

Savage-Dunn C, Gleason RJ, Liu J, Padgett RW.

Methods Mol Biol. 2019;1891:51-73. doi: 10.1007/978-1-4939-8904-1_6.

PMID:
30414126
3.

bantam microRNA is a negative regulator of the Drosophila decapentaplegic pathway.

Kane NS, Vora M, Padgett RW, Li Y.

Fly (Austin). 2018;12(2):105-117. doi: 10.1080/19336934.2018.1499370. Epub 2018 Aug 19.

4.

C. elegans SMA-10 regulates BMP receptor trafficking.

Gleason RJ, Vora M, Li Y, Kane NS, Liao K, Padgett RW.

PLoS One. 2017 Jul 13;12(7):e0180681. doi: 10.1371/journal.pone.0180681. eCollection 2017.

5.

The TGF-β Family in Caenorhabditis elegans.

Savage-Dunn C, Padgett RW.

Cold Spring Harb Perspect Biol. 2017 Jun 1;9(6). pii: a022178. doi: 10.1101/cshperspect.a022178. Review.

6.

Efficient Screening of CRISPR/Cas9-Induced Events in Drosophila Using a Co-CRISPR Strategy.

Kane NS, Vora M, Varre KJ, Padgett RW.

G3 (Bethesda). 2017 Jan 5;7(1):87-93. doi: 10.1534/g3.116.036723.

7.

Matters of context guide future research in TGFβ superfamily signaling.

Akhurst RJ, Padgett RW.

Sci Signal. 2015 Oct 20;8(399):re10. doi: 10.1126/scisignal.aad0416. Review.

PMID:
26486175
8.

BMP signaling requires retromer-dependent recycling of the type I receptor.

Gleason RJ, Akintobi AM, Grant BD, Padgett RW.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2578-83. doi: 10.1073/pnas.1319947111. Epub 2014 Feb 3.

9.

bantam is required for optic lobe development and glial cell proliferation.

Li Y, Padgett RW.

PLoS One. 2012;7(3):e32910. doi: 10.1371/journal.pone.0032910. Epub 2012 Mar 8.

10.

Regulation of genes affecting body size and innate immunity by the DBL-1/BMP-like pathway in Caenorhabditis elegans.

Roberts AF, Gumienny TL, Gleason RJ, Wang H, Padgett RW.

BMC Dev Biol. 2010 Jun 7;10:61. doi: 10.1186/1471-213X-10-61.

11.

Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling.

Gumienny TL, Macneil L, Zimmerman CM, Wang H, Chin L, Wrana JL, Padgett RW.

PLoS Genet. 2010 May 20;6(5):e1000963. doi: 10.1371/journal.pgen.1000963.

12.

Circadian regulation of a limited set of conserved microRNAs in Drosophila.

Yang M, Lee JE, Padgett RW, Edery I.

BMC Genomics. 2008 Feb 19;9:83. doi: 10.1186/1471-2164-9-83.

13.

TGFbeta superfamily signaling: notes from the desert.

Padgett RW, Reiss M.

Development. 2007 Oct;134(20):3565-9. Review.

14.

Glypican LON-2 is a conserved negative regulator of BMP-like signaling in Caenorhabditis elegans.

Gumienny TL, MacNeil LT, Wang H, de Bono M, Wrana JL, Padgett RW.

Curr Biol. 2007 Jan 23;17(2):159-64.

15.

Rational probe optimization and enhanced detection strategy for microRNAs using microarrays.

Goff LA, Yang M, Bowers J, Getts RC, Padgett RW, Hart RP.

RNA Biol. 2005 Jul-Sep;2(3):93-100. Epub 2005 Jul 20.

PMID:
17114923
16.

Modulated microRNA expression during adult lifespan in Caenorhabditis elegans.

Ibáñez-Ventoso C, Yang M, Guo S, Robins H, Padgett RW, Driscoll M.

Aging Cell. 2006 Jun;5(3):235-46.

17.

BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary.

Kirilly D, Spana EP, Perrimon N, Padgett RW, Xie T.

Dev Cell. 2005 Nov;9(5):651-62.

19.

MicroRNAs: Small regulators with a big impact.

Yang M, Li Y, Padgett RW.

Cytokine Growth Factor Rev. 2005 Aug-Oct;16(4-5):387-93. Review.

PMID:
15869899
20.

C. elegans serine-threonine kinase KIN-29 modulates TGFbeta signaling and regulates body size formation.

Maduzia LL, Roberts AF, Wang H, Lin X, Chin LJ, Zimmerman CM, Cohen S, Feng XH, Padgett RW.

BMC Dev Biol. 2005 Apr 19;5:8.

21.

Incorporating structure to predict microRNA targets.

Robins H, Li Y, Padgett RW.

Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4006-9. Epub 2005 Feb 28.

22.

Methylation as a crucial step in plant microRNA biogenesis.

Yu B, Yang Z, Li J, Minakhina S, Yang M, Padgett RW, Steward R, Chen X.

Science. 2005 Feb 11;307(5711):932-5.

23.

Genome-wide microarray analysis of TGFbeta signaling in the Drosophila brain.

Yang M, Nelson D, Funakoshi Y, Padgett RW.

BMC Dev Biol. 2004 Oct 8;4:14.

24.

Genetic screen for small body size mutants in C. elegans reveals many TGFbeta pathway components.

Savage-Dunn C, Maduzia LL, Zimmerman CM, Roberts AF, Cohen S, Tokarz R, Padgett RW.

Genesis. 2003 Apr;35(4):239-47.

PMID:
12717735
25.

Insulin worms its way into the spotlight.

Nelson DW, Padgett RW.

Genes Dev. 2003 Apr 1;17(7):813-8. Review. No abstract available.

26.

A small issue addressed.

Gumienny TL, Padgett RW.

Bioessays. 2003 Apr;25(4):305-8.

PMID:
12655636
27.
28.

The other side of TGF-beta superfamily signal regulation: thinking outside the cell.

Gumienny T, Padgett RW.

Trends Endocrinol Metab. 2002 Sep;13(7):295-9. Review.

PMID:
12163231
29.

lon-1 regulates Caenorhabditis elegans body size downstream of the dbl-1 TGF beta signaling pathway.

Maduzia LL, Gumienny TL, Zimmerman CM, Wang H, Shetgiri P, Krishna S, Roberts AF, Padgett RW.

Dev Biol. 2002 Jun 15;246(2):418-28.

30.

New developments for TGFbeta.

Padgett RW, Patterson GI.

Dev Cell. 2001 Sep;1(3):343-9.

31.

SMA-3 smad has specific and critical functions in DBL-1/SMA-6 TGFbeta-related signaling.

Savage-Dunn C, Tokarz R, Wang H, Cohen S, Giannikas C, Padgett RW.

Dev Biol. 2000 Jul 1;223(1):70-6.

32.

Transforming growth factor beta signaling mediators and modulators.

Zimmerman CM, Padgett RW.

Gene. 2000 May 16;249(1-2):17-30. Review.

PMID:
10831835
33.

TGFbeta signaling pathways and human diseases.

Padgett RW.

Cancer Metastasis Rev. 1999;18(2):247-59. Review.

PMID:
10728987
34.

Genetic approaches to TGFbeta signaling pathways.

Das P, Maduzia LL, Padgett RW.

Cytokine Growth Factor Rev. 1999 Sep-Dec;10(3-4):179-86. Review. No abstract available.

PMID:
10647775
35.

TGF beta-related pathways. Roles in Caenorhabditis elegans development.

Patterson GI, Padgett RW.

Trends Genet. 2000 Jan;16(1):27-33. Review.

PMID:
10637628
36.

Intracellular signaling: Fleshing out the TGFbeta pathway.

Padgett RW.

Curr Biol. 1999 Jun 3;9(11):R408-11. Review.

37.

Drosophila dSmad2 and Atr-I transmit activin/TGFbeta signals.

Das P, Inoue H, Baker JC, Beppu H, Kawabata M, Harland RM, Miyazono K, Padgett RW.

Genes Cells. 1999 Feb;4(2):123-34.

39.

A BMP homolog acts as a dose-dependent regulator of body size and male tail patterning in Caenorhabditis elegans.

Suzuki Y, Yandell MD, Roy PJ, Krishna S, Savage-Dunn C, Ross RM, Padgett RW, Wood WB.

Development. 1999 Jan;126(2):241-50.

40.

Pioneer axon guidance by UNC-129, a C. elegans TGF-beta.

Colavita A, Krishna S, Zheng H, Padgett RW, Culotti JG.

Science. 1998 Jul 31;281(5377):706-9.

41.

TGF-beta signaling, Smads, and tumor suppressors.

Padgett RW, Das P, Krishna S.

Bioessays. 1998 May;20(5):382-90. Review.

PMID:
9670811
42.

The Drosophila gene Medea demonstrates the requirement for different classes of Smads in dpp signaling.

Das P, Maduzia LL, Wang H, Finelli AL, Cho SH, Smith MM, Padgett RW.

Development. 1998 Apr;125(8):1519-28.

43.

Smads are the central component in transforming growth factor-beta signaling.

Padgett RW, Cho SH, Evangelista C.

Pharmacol Ther. 1998 Apr;78(1):47-52. Review.

PMID:
9593329
44.

Drosophila MAD, a member of the Smad family, translocates to the nucleus upon stimulation of the dpp pathway.

Maduzia LL, Padgett RW.

Biochem Biophys Res Commun. 1997 Sep 18;238(2):595-8.

PMID:
9299558
45.

Genetic and biochemical analysis of TGF beta signal transduction.

Padgett RW, Savage C, Das P.

Cytokine Growth Factor Rev. 1997 Mar;8(1):1-9. Review.

PMID:
9174659
46.

Molecular evolution at the decapentaplegic locus in Drosophila.

Newfeld SJ, Padgett RW, Findley SD, Richter BG, Sanicola M, de Cuevas M, Gelbart WM.

Genetics. 1997 Feb;145(2):297-309.

47.

The Drosophila decapentaplegic and short gastrulation genes function antagonistically during adult wing vein development.

Yu K, Sturtevant MA, Biehs B, François V, Padgett RW, Blackman RK, Bier E.

Development. 1996 Dec;122(12):4033-44.

48.

Nomenclature: vertebrate mediators of TGFbeta family signals.

Derynck R, Gelbart WM, Harland RM, Heldin CH, Kern SE, Massagué J, Melton DA, Mlodzik M, Padgett RW, Roberts AB, Smith J, Thomsen GH, Vogelstein B, Wang XF.

Cell. 1996 Oct 18;87(2):173. No abstract available.

49.

Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth.

Yingling JM, Das P, Savage C, Zhang M, Padgett RW, Wang XF.

Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):8940-4.

50.

The TGF-beta signaling pathway is essential for Drosophila oogenesis.

Twombly V, Blackman RK, Jin H, Graff JM, Padgett RW, Gelbart WM.

Development. 1996 May;122(5):1555-65.

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