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Items: 1 to 50 of 65

1.

Breast cancer metastasis through the lympho-vascular system.

Nathanson SD, Krag D, Kuerer HM, Newman LA, Brown M, Kerjaschki D, Pereira ER, Padera TP.

Clin Exp Metastasis. 2018 May 23. doi: 10.1007/s10585-018-9902-1. [Epub ahead of print]

PMID:
29796854
2.

Non-invasive detection of severe neutropenia in chemotherapy patients by optical imaging of nailfold microcirculation.

Bourquard A, Pablo-Trinidad A, Butterworth I, Sánchez-Ferro Á, Cerrato C, Humala K, Fabra Urdiola M, Del Rio C, Valles B, Tucker-Schwartz JM, Lee ES, Vakoc BJ, Padera TP, Ledesma-Carbayo MJ, Chen YB, Hochberg EP, Gray ML, Castro-González C.

Sci Rep. 2018 Mar 28;8(1):5301. doi: 10.1038/s41598-018-23591-0.

3.

Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice.

Pereira ER, Kedrin D, Seano G, Gautier O, Meijer EFJ, Jones D, Chin SM, Kitahara S, Bouta EM, Chang J, Beech E, Jeong HS, Carroll MC, Taghian AG, Padera TP.

Science. 2018 Mar 23;359(6382):1403-1407. doi: 10.1126/science.aal3622. Epub 2018 Mar 22.

PMID:
29567713
4.

Growth and Immune Evasion of Lymph Node Metastasis.

Jones D, Pereira ER, Padera TP.

Front Oncol. 2018 Feb 21;8:36. doi: 10.3389/fonc.2018.00036. eCollection 2018. Review.

5.

Lymphatic function measurements influenced by contrast agent volume and body position.

Bouta EM, Blatter C, Ruggieri TA, Meijer EF, Munn LL, Vakoc BJ, Padera TP.

JCI Insight. 2018 Jan 25;3(2). pii: 96591. doi: 10.1172/jci.insight.96591. [Epub ahead of print]

6.

Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction.

Jones D, Meijer EFJ, Blatter C, Liao S, Pereira ER, Bouta EM, Jung K, Chin SM, Huang P, Munn LL, Vakoc BJ, Otto M, Padera TP.

Sci Transl Med. 2018 Jan 17;10(424). pii: eaam7964. doi: 10.1126/scitranslmed.aam7964.

7.

Depolarization signatures map gold nanorods within biological tissue.

Lippok N, Villiger M, Albanese A, Meijer EFJ, Chung K, Padera TP, Bhatia SN, Bouma BE.

Nat Photonics. 2017;11:583-588. doi: 10.1038/nphoton.2017.128. Epub 2017 Jul 31.

8.

Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer.

Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK, Clark JW, Willett CG, Yun SH, Luster AD, Padera TP, Jain RK, Fukumura D.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):10455-10460. doi: 10.1073/pnas.1710754114. Epub 2017 Sep 12.

9.

Simultaneous measurements of lymphatic vessel contraction, flow and valve dynamics in multiple lymphangions using optical coherence tomography.

Blatter C, Meijer EFJ, Padera TP, Vakoc BJ.

J Biophotonics. 2017 Jul 12. doi: 10.1002/jbio.201700017. [Epub ahead of print]

PMID:
28700145
10.

Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.

Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, Fukumura D.

J Clin Invest. 2017 Aug 1;127(8):3039-3051. doi: 10.1172/JCI93182. Epub 2017 Jul 10.

11.

Murine chronic lymph node window for longitudinal intravital lymph node imaging.

Meijer EFJ, Jeong HS, Pereira ER, Ruggieri TA, Blatter C, Vakoc BJ, Padera TP.

Nat Protoc. 2017 Aug;12(8):1513-1520. doi: 10.1038/nprot.2017.045. Epub 2017 Jul 6.

12.

Lymph node effective vascular permeability and chemotherapy uptake.

Meijer EFJ, Blatter C, Chen IX, Bouta E, Jones D, Pereira ER, Jung K, Vakoc BJ, Baish JW, Padera TP.

Microcirculation. 2017 Aug;24(6). doi: 10.1111/micc.12381.

13.

Synchronization and Random Triggering of Lymphatic Vessel Contractions.

Baish JW, Kunert C, Padera TP, Munn LL.

PLoS Comput Biol. 2016 Dec 9;12(12):e1005231. doi: 10.1371/journal.pcbi.1005231. eCollection 2016 Dec.

14.

Measuring Vascular Permeability In Vivo.

Meijer EF, Baish JW, Padera TP, Fukumura D.

Methods Mol Biol. 2016;1458:71-85. doi: 10.1007/978-1-4939-3801-8_6.

15.

In vivo label-free measurement of lymph flow velocity and volumetric flow rates using Doppler optical coherence tomography.

Blatter C, Meijer EF, Nam AS, Jones D, Bouma BE, Padera TP, Vakoc BJ.

Sci Rep. 2016 Jul 5;6:29035. doi: 10.1038/srep29035.

16.

The Lymphatic System in Disease Processes and Cancer Progression.

Padera TP, Meijer EF, Munn LL.

Annu Rev Biomed Eng. 2016 Jul 11;18:125-58. doi: 10.1146/annurev-bioeng-112315-031200. Epub 2016 Feb 5. Review.

17.

Reply to Davis: Nitric oxide regulates lymphatic contractions.

Kunert C, Baish JW, Liao S, Padera TP, Munn LL.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E106. doi: 10.1073/pnas.1522233113. Epub 2015 Dec 30. No abstract available.

18.

Solid stress and elastic energy as measures of tumour mechanopathology.

Nia HT, Liu H, Seano G, Datta M, Jones D, Rahbari N, Incio J, Chauhan VP, Jung K, Martin JD, Askoxylakis V, Padera TP, Fukumura D, Boucher Y, Hornicek FJ, Grodzinsky AJ, Baish JW, Munn LL, Jain RK.

Nat Biomed Eng. 2016;1. pii: 0004. doi: 10.1038/s41551-016-0004. Epub 2016 Nov 28.

19.

Mechanobiological oscillators control lymph flow.

Kunert C, Baish JW, Liao S, Padera TP, Munn LL.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10938-43. doi: 10.1073/pnas.1508330112. Epub 2015 Aug 17.

20.

Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases.

Jeong HS, Jones D, Liao S, Wattson DA, Cui CH, Duda DG, Willett CG, Jain RK, Padera TP.

J Natl Cancer Inst. 2015 Jun 10;107(9). pii: djv155. doi: 10.1093/jnci/djv155. Print 2015 Sep.

21.

Angiopoietin-4 increases permeability of blood vessels and promotes lymphatic dilation.

Kesler CT, Pereira ER, Cui CH, Nelson GM, Masuck DJ, Baish JW, Padera TP.

FASEB J. 2015 Sep;29(9):3668-77. doi: 10.1096/fj.14-268920. Epub 2015 May 14.

22.

Significance of lymph node metastasis in cancer dissemination of head and neck cancer.

Cho JK, Hyun SH, Choi N, Kim MJ, Padera TP, Choi JY, Jeong HS.

Transl Oncol. 2015 Apr;8(2):119-25. doi: 10.1016/j.tranon.2015.03.001.

23.

Editorial: rapid growth in the field of lymphatic biology.

Padera TP.

Semin Cell Dev Biol. 2015 Feb;38:53-4. doi: 10.1016/j.semcdb.2015.03.007. No abstract available.

PMID:
25868083
24.

Local failure in parameningeal rhabdomyosarcoma correlates with poor response to induction chemotherapy.

Ladra MM, Mandeville HC, Niemierko A, Padera TP, Friedmann AM, MacDonald SM, Ebb D, Chen YL, Tarbell NJ, Yock TI.

Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):358-67. doi: 10.1016/j.ijrobp.2015.01.049. Epub 2015 Apr 8.

25.

The lymph node microenvironment and its role in the progression of metastatic cancer.

Pereira ER, Jones D, Jung K, Padera TP.

Semin Cell Dev Biol. 2015 Feb;38:98-105. doi: 10.1016/j.semcdb.2015.01.008. Epub 2015 Jan 22. Review.

26.

Cardiac and inflammatory biomarkers do not correlate with volume of heart or lung receiving radiation.

Kuo AH, Ancukiewicz M, Kozak KR, Yock TI, Padera TP.

Radiat Oncol. 2015 Jan 9;10:5. doi: 10.1186/s13014-014-0324-1.

27.

Method for the quantitative measurement of collecting lymphatic vessel contraction in mice.

Liao S, Jones D, Cheng G, Padera TP.

J Biol Methods. 2014;1(2). pii: e6.

28.

Compression of pancreatic tumor blood vessels by hyaluronan is caused by solid stress and not interstitial fluid pressure.

Chauhan VP, Boucher Y, Ferrone CR, Roberge S, Martin JD, Stylianopoulos T, Bardeesy N, DePinho RA, Padera TP, Munn LL, Jain RK.

Cancer Cell. 2014 Jul 14;26(1):14-5. doi: 10.1016/j.ccr.2014.06.003. No abstract available.

29.

Imaging the lymphatic system.

Munn LL, Padera TP.

Microvasc Res. 2014 Nov;96:55-63. doi: 10.1016/j.mvr.2014.06.006. Epub 2014 Jun 21. Review.

30.

Novel molecular pathways in Gorham disease: implications for treatment.

Hagendoorn J, Yock TI, Borel Rinkes IH, Padera TP, Ebb DH.

Pediatr Blood Cancer. 2014 Mar;61(3):401-6. doi: 10.1002/pbc.24832. Epub 2013 Nov 8. Review.

31.

Vascular endothelial growth factor-C enhances radiosensitivity of lymphatic endothelial cells.

Kesler CT, Kuo AH, Wong HK, Masuck DJ, Shah JL, Kozak KR, Held KD, Padera TP.

Angiogenesis. 2014 Apr;17(2):419-27. doi: 10.1007/s10456-013-9400-7. Epub 2013 Nov 8.

32.

Lymphatic function and immune regulation in health and disease.

Liao S, Padera TP.

Lymphat Res Biol. 2013 Sep;11(3):136-43. doi: 10.1089/lrb.2013.0012. Epub 2013 Sep 11. Review. No abstract available.

33.

Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression.

Goel S, Gupta N, Walcott BP, Snuderl M, Kesler CT, Kirkpatrick ND, Heishi T, Huang Y, Martin JD, Ager E, Samuel R, Wang S, Yazbek J, Vakoc BJ, Peterson RT, Padera TP, Duda DG, Fukumura D, Jain RK.

J Natl Cancer Inst. 2013 Aug 21;105(16):1188-201. doi: 10.1093/jnci/djt164. Epub 2013 Jul 30. Erratum in: J Natl Cancer Inst. 2013 Nov 20;105(22):1762.

34.

Lymphatic vessels in health and disease.

Kesler CT, Liao S, Munn LL, Padera TP.

Wiley Interdiscip Rev Syst Biol Med. 2013 Jan-Feb;5(1):111-24. doi: 10.1002/wsbm.1201. Epub 2012 Dec 3. Review.

35.

Video-rate resonant scanning multiphoton microscopy: An emerging technique for intravital imaging of the tumor microenvironment.

Kirkpatrick ND, Chung E, Cook DC, Han X, Gruionu G, Liao S, Munn LL, Padera TP, Fukumura D, Jain RK.

Intravital. 2012;1(1). doi: 10.4161/intv.21557.

36.

Impaired lymphatic contraction associated with immunosuppression.

Liao S, Cheng G, Conner DA, Huang Y, Kucherlapati RS, Munn LL, Ruddle NH, Jain RK, Fukumura D, Padera TP.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18784-9. doi: 10.1073/pnas.1116152108. Epub 2011 Nov 7. Erratum in: Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5992.

37.

Notch leads lymphatics and links them to blood vessels.

Liao S, Padera TP, Jain RK.

Arterioscler Thromb Vasc Biol. 2010 Sep;30(9):1682-3. doi: 10.1161/ATVBAHA.110.210633. No abstract available.

38.

Lymphotoxin-alpha contributes to lymphangiogenesis.

Mounzer RH, Svendsen OS, Baluk P, Bergman CM, Padera TP, Wiig H, Jain RK, McDonald DM, Ruddle NH.

Blood. 2010 Sep 23;116(12):2173-82. doi: 10.1182/blood-2009-12-256065. Epub 2010 Jun 21.

39.

Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging.

Vakoc BJ, Lanning RM, Tyrrell JA, Padera TP, Bartlett LA, Stylianopoulos T, Munn LL, Tearney GJ, Fukumura D, Jain RK, Bouma BE.

Nat Med. 2009 Oct;15(10):1219-23. doi: 10.1038/nm.1971. Epub 2009 Sep 13.

40.

Hearing improvement after bevacizumab in patients with neurofibromatosis type 2.

Plotkin SR, Stemmer-Rachamimov AO, Barker FG 2nd, Halpin C, Padera TP, Tyrrell A, Sorensen AG, Jain RK, di Tomaso E.

N Engl J Med. 2009 Jul 23;361(4):358-67. doi: 10.1056/NEJMoa0902579. Epub 2009 Jul 8.

41.

Multiscale measurements distinguish cellular and interstitial hindrances to diffusion in vivo.

Chauhan VP, Lanning RM, Diop-Frimpong B, Mok W, Brown EB, Padera TP, Boucher Y, Jain RK.

Biophys J. 2009 Jul 8;97(1):330-6. doi: 10.1016/j.bpj.2009.03.064.

42.

Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis.

Lahdenranta J, Hagendoorn J, Padera TP, Hoshida T, Nelson G, Kashiwagi S, Jain RK, Fukumura D.

Cancer Res. 2009 Apr 1;69(7):2801-8. doi: 10.1158/0008-5472.CAN-08-4051. Epub 2009 Mar 24.

43.

Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.

Luong MX, Tam J, Lin Q, Hagendoorn J, Moore KJ, Padera TP, Seed B, Fukumura D, Kucherlapati R, Jain RK.

J Cell Physiol. 2009 May;219(2):430-7. doi: 10.1002/jcp.21686.

44.

In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts.

Perentes JY, McKee TD, Ley CD, Mathiew H, Dawson M, Padera TP, Munn LL, Jain RK, Boucher Y.

Nat Methods. 2009 Feb;6(2):143-5. doi: 10.1038/nmeth.1295. Epub 2009 Jan 18.

45.

VEGFR3: a new target for antiangiogenesis therapy?

Padera TP, Jain RK.

Dev Cell. 2008 Aug;15(2):178-9. doi: 10.1016/j.devcel.2008.07.014.

46.

Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib.

Padera TP, Kuo AH, Hoshida T, Liao S, Lobo J, Kozak KR, Fukumura D, Jain RK.

Mol Cancer Ther. 2008 Aug;7(8):2272-9. doi: 10.1158/1535-7163.MCT-08-0182. Epub 2008 Aug 6.

47.

Differential gene expression of primary cultured lymphatic and blood vascular endothelial cells.

Nelson GM, Padera TP, Garkavtsev I, Shioda T, Jain RK.

Neoplasia. 2007 Dec;9(12):1038-45.

48.

Anti-VEGFR-3 therapy and lymph node metastasis [corrected].

Padera TP, Ancukiewicz M, Hoshida T, Fukumura D, Jain RK.

Cancer Res. 2007 May 15;67(10):5055; author reply 5056. No abstract available. Erratum in: Cancer Res. 2007 Jul 1;67(13):6528.

49.

Platelet-derived growth factor receptor-beta in Gorham's disease.

Hagendoorn J, Padera TP, Yock TI, Nielsen GP, di Tomaso E, Duda DG, Delaney TF, Gaissert HA, Pearce J, Rosenberg AE, Jain RK, Ebb DH.

Nat Clin Pract Oncol. 2006 Dec;3(12):693-7.

50.

Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications.

Hoshida T, Isaka N, Hagendoorn J, di Tomaso E, Chen YL, Pytowski B, Fukumura D, Padera TP, Jain RK.

Cancer Res. 2006 Aug 15;66(16):8065-75.

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