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Items: 32

1.

Approaches and Recent Developments for the Commercial Production of Semi-synthetic Artemisinin.

Kung SH, Lund S, Murarka A, McPhee D, Paddon CJ.

Front Plant Sci. 2018 Jan 31;9:87. doi: 10.3389/fpls.2018.00087. eCollection 2018. Review.

2.

Developing fermentative terpenoid production for commercial usage.

Leavell MD, McPhee DJ, Paddon CJ.

Curr Opin Biotechnol. 2016 Feb;37:114-119. doi: 10.1016/j.copbio.2015.10.007. Epub 2015 Dec 23. Review.

PMID:
26723008
3.

Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development.

Paddon CJ, Keasling JD.

Nat Rev Microbiol. 2014 May;12(5):355-67. doi: 10.1038/nrmicro3240. Epub 2014 Apr 1. Review.

PMID:
24686413
4.

High-level semi-synthetic production of the potent antimalarial artemisinin.

Paddon CJ, Westfall PJ, Pitera DJ, Benjamin K, Fisher K, McPhee D, Leavell MD, Tai A, Main A, Eng D, Polichuk DR, Teoh KH, Reed DW, Treynor T, Lenihan J, Fleck M, Bajad S, Dang G, Dengrove D, Diola D, Dorin G, Ellens KW, Fickes S, Galazzo J, Gaucher SP, Geistlinger T, Henry R, Hepp M, Horning T, Iqbal T, Jiang H, Kizer L, Lieu B, Melis D, Moss N, Regentin R, Secrest S, Tsuruta H, Vazquez R, Westblade LF, Xu L, Yu M, Zhang Y, Zhao L, Lievense J, Covello PS, Keasling JD, Reiling KK, Renninger NS, Newman JD.

Nature. 2013 Apr 25;496(7446):528-32. doi: 10.1038/nature12051. Epub 2013 Apr 10.

PMID:
23575629
5.

De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology.

Nijkamp JF, van den Broek M, Datema E, de Kok S, Bosman L, Luttik MA, Daran-Lapujade P, Vongsangnak W, Nielsen J, Heijne WH, Klaassen P, Paddon CJ, Platt D, K├Âtter P, van Ham RC, Reinders MJ, Pronk JT, de Ridder D, Daran JM.

Microb Cell Fact. 2012 Mar 26;11:36. doi: 10.1186/1475-2859-11-36.

6.

Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin.

Westfall PJ, Pitera DJ, Lenihan JR, Eng D, Woolard FX, Regentin R, Horning T, Tsuruta H, Melis DJ, Owens A, Fickes S, Diola D, Benjamin KR, Keasling JD, Leavell MD, McPhee DJ, Renninger NS, Newman JD, Paddon CJ.

Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):E111-8. doi: 10.1073/pnas.1110740109. Epub 2012 Jan 12.

7.

Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: contributory role in hyaluronan accumulation in thyroid dysfunction.

Zhang L, Bowen T, Grennan-Jones F, Paddon C, Giles P, Webber J, Steadman R, Ludgate M.

J Biol Chem. 2009 Sep 25;284(39):26447-55. doi: 10.1074/jbc.M109.003616. Epub 2009 Jul 24.

8.

Gsalpha signalling suppresses PPARgamma2 generation and inhibits 3T3L1 adipogenesis.

Zhang L, Paddon C, Lewis MD, Grennan-Jones F, Ludgate M.

J Endocrinol. 2009 Aug;202(2):207-15. doi: 10.1677/JOE-09-0099. Epub 2009 May 21.

9.

High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli.

Tsuruta H, Paddon CJ, Eng D, Lenihan JR, Horning T, Anthony LC, Regentin R, Keasling JD, Renninger NS, Newman JD.

PLoS One. 2009;4(2):e4489. doi: 10.1371/journal.pone.0004489. Epub 2009 Feb 16.

10.

Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid.

Ro DK, Ouellet M, Paradise EM, Burd H, Eng D, Paddon CJ, Newman JD, Keasling JD.

BMC Biotechnol. 2008 Nov 4;8:83. doi: 10.1186/1472-6750-8-83.

11.

General theory of cathodic and anodic stripping voltammetry at solid electrodes: mathematical modeling and numerical simulations.

Ward Jones SE, Chevallier FG, Paddon CA, Compton RG.

Anal Chem. 2007 Jun 1;79(11):4110-9. Epub 2007 May 1.

PMID:
17469796
12.

Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli.

Pitera DJ, Paddon CJ, Newman JD, Keasling JD.

Metab Eng. 2007 Mar;9(2):193-207. Epub 2006 Nov 23.

PMID:
17239639
13.
14.

Biological effects of thyrotropin receptor activation on human orbital preadipocytes.

Zhang L, Baker G, Janus D, Paddon CA, Fuhrer D, Ludgate M.

Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5197-203.

15.
16.

Oxidation of anthracene on platinum macro- and micro-electrodes: Sonoelectrochemical, cryoelectrochemical and sonocryoelectrochemical studies.

Paddon CA, Banks CE, Davies IG, Compton RG.

Ultrason Sonochem. 2006 Feb;13(2):126-32. Epub 2005 Mar 17.

PMID:
16293520
17.

Hydrophobic silica sol-gel films for biphasic electrodes and porotrodes.

McKenzie KJ, Niedziolka J, Paddon CA, Marken F, Rozniecka E, Opallo M.

Analyst. 2004 Dec;129(12):1181-5. Epub 2004 Sep 30.

PMID:
15565215
18.

The global transcriptional response of Bacillus subtilis to peroxide stress is coordinated by three transcription factors.

Helmann JD, Wu MF, Gaballa A, Kobel PA, Morshedi MM, Fawcett P, Paddon C.

J Bacteriol. 2003 Jan;185(1):243-53.

20.

Global transcriptional response of Bacillus subtilis to heat shock.

Helmann JD, Wu MF, Kobel PA, Gamo FJ, Wilson M, Morshedi MM, Navre M, Paddon C.

J Bacteriol. 2001 Dec;183(24):7318-28.

21.

Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein alpha-subunit chimeras.

Brown AJ, Dyos SL, Whiteway MS, White JH, Watson MA, Marzioch M, Clare JJ, Cousens DJ, Paddon C, Plumpton C, Romanos MA, Dowell SJ.

Yeast. 2000 Jan 15;16(1):11-22.

22.

Mutations in the Saccharomyces cerevisiae gene SAC1 cause multiple drug sensitivity.

Hughes WE, Pocklington MJ, Orr E, Paddon CJ.

Yeast. 1999 Aug;15(11):1111-24.

23.

Recombination-mediated PCR-directed plasmid construction in vivo in yeast.

Oldenburg KR, Vo KT, Michaelis S, Paddon C.

Nucleic Acids Res. 1997 Jan 15;25(2):451-2.

24.

Analysis of the localization of STE6/CFTR chimeras in a Saccharomyces cerevisiae model for the cystic fibrosis defect CFTR delta F508.

Paddon C, Loayza D, Vangelista L, Solari R, Michaelis S.

Mol Microbiol. 1996 Mar;19(5):1007-17.

PMID:
8830258
26.
29.

Translation and processing of Bacillus amyloliquefaciens extracellular RNase.

Paddon CJ, Vasantha N, Hartley RW.

J Bacteriol. 1989 Feb;171(2):1185-7.

31.

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