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Items: 16

1.

Structures of two ArsR As(III)-responsive transcriptional repressors: Implications for the mechanism of derepression.

Prabaharan C, Kandavelu P, Packianathan C, Rosen BP, Thiyagarajan S.

J Struct Biol. 2019 May 25. pii: S1047-8477(19)30113-3. doi: 10.1016/j.jsb.2019.05.009. [Epub ahead of print]

PMID:
31136796
2.

The Structure of an As(III) S-Adenosylmethionine Methyltransferase with 3-Coordinately Bound As(III) Depicts the First Step in Catalysis.

Packianathan C, Kandavelu P, Rosen BP.

Biochemistry. 2018 Jul 17;57(28):4083-4092. doi: 10.1021/acs.biochem.8b00457. Epub 2018 Jun 26.

PMID:
29894638
3.

Reorientation of the Methyl Group in MAs(III) is the Rate-Limiting Step in the ArsM As(III) S-Adenosylmethionine Methyltransferase Reaction.

Packianathan C, Li J, Kandavelu P, Sankaran B, Rosen BP.

ACS Omega. 2018 Mar;3(3):3104-3112. doi: 10.1021/acsomega.8b00197. Epub 2018 Mar 14.

4.

Arsenic methylation by a novel ArsM As(III) S-adenosylmethionine methyltransferase that requires only two conserved cysteine residues.

Huang K, Xu Y, Packianathan C, Gao F, Chen C, Zhang J, Shen Q, Rosen BP, Zhao FJ.

Mol Microbiol. 2018 Jan;107(2):265-276. doi: 10.1111/mmi.13882. Epub 2017 Nov 23.

5.

Nonsynonymous Polymorphisms in the Human AS3MT Arsenic Methylation Gene: Implications for Arsenic Toxicity.

Li J, Packianathan C, Rossman TG, Rosen BP.

Chem Res Toxicol. 2017 Jul 17;30(7):1481-1491. doi: 10.1021/acs.chemrestox.7b00113. Epub 2017 Jun 19.

6.

Chikungunya and bilateral sacroiliitis-is there a link?

Nisar MK, Packianathan C.

Eur J Rheumatol. 2017 Mar;4(1):81-82. doi: 10.5152/eurjrheum.2015.0071. Epub 2016 Feb 1. No abstract available.

7.

High-throughput screening-compatible assays of As(III) S-adenosylmethionine methyltransferase activity.

Dong H, Xu W, Pillai JK, Packianathan C, Rosen BP.

Anal Biochem. 2015 Jul 1;480:67-73. doi: 10.1016/j.ab.2015.04.011. Epub 2015 Apr 10.

8.

A disulfide-bond cascade mechanism for arsenic(III) S-adenosylmethionine methyltransferase.

Marapakala K, Packianathan C, Ajees AA, Dheeman DS, Sankaran B, Kandavelu P, Rosen BP.

Acta Crystallogr D Biol Crystallogr. 2015 Mar;71(Pt 3):505-15. doi: 10.1107/S1399004714027552. Epub 2015 Feb 26.

9.

Pathway of human AS3MT arsenic methylation.

Dheeman DS, Packianathan C, Pillai JK, Rosen BP.

Chem Res Toxicol. 2014 Nov 17;27(11):1979-89. doi: 10.1021/tx500313k. Epub 2014 Oct 30.

10.

Crystallization and preliminary X-ray crystallographic studies of CrArsM, an arsenic(III) S-adenosylmethionine methyltransferase from Chlamydomonas reinhardtii.

Packianathan C, Pillai JK, Riaz A, Kandavelu P, Sankaran B, Rosen BP.

Acta Crystallogr F Struct Biol Commun. 2014 Oct;70(Pt 10):1385-8. doi: 10.1107/S2053230X14018469. Epub 2014 Sep 25.

11.

Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities.

Lopez SM, Hodgson MC, Packianathan C, Bingol-Ozakpinar O, Uras F, Rosen BP, Agoulnik IU.

Biochem Biophys Res Commun. 2013 Oct 18;440(2):277-82. doi: 10.1016/j.bbrc.2013.09.077. Epub 2013 Sep 23.

12.

Structure of an As(III) S-adenosylmethionine methyltransferase: insights into the mechanism of arsenic biotransformation.

Ajees AA, Marapakala K, Packianathan C, Sankaran B, Rosen BP.

Biochemistry. 2012 Jul 10;51(27):5476-85. Epub 2012 Jun 29.

13.

Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in Danio rerio.

Hamdi M, Yoshinaga M, Packianathan C, Qin J, Hallauer J, McDermott JR, Yang HC, Tsai KJ, Liu Z.

Toxicol Appl Pharmacol. 2012 Jul 15;262(2):185-93. doi: 10.1016/j.taap.2012.04.035. Epub 2012 May 7.

14.

Conformational changes in the hepatitis B virus core protein are consistent with a role for allostery in virus assembly.

Packianathan C, Katen SP, Dann CE 3rd, Zlotnick A.

J Virol. 2010 Feb;84(3):1607-15. doi: 10.1128/JVI.02033-09. Epub 2009 Nov 25.

15.

A mutant hepatitis B virus core protein mimics inhibitors of icosahedral capsid self-assembly.

Bourne CR, Katen SP, Fulz MR, Packianathan C, Zlotnick A.

Biochemistry. 2009 Mar 3;48(8):1736-42. doi: 10.1021/bi801814y.

16.

Moderate exercise and fibrinolytic potential in obese sedentary men with metabolic syndrome.

Morris PJ, Packianathan CI, Van Blerk CJ, Finer N.

Obes Res. 2003 Nov;11(11):1333-8.

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