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Items: 1 to 50 of 128

1.

Disruption of a -35 kb Enhancer Impairs CTCF Binding and MLH1 Expression in Colorectal Cells.

Liu Q, Thoms JAI, Nunez AC, Huang Y, Knezevic K, Packham D, Poulos RC, Williams R, Beck D, Hawkins NJ, Ward RL, Wong JWH, Hesson LB, Sloane MA, Pimanda JE.

Clin Cancer Res. 2018 Sep 15;24(18):4602-4611. doi: 10.1158/1078-0432.CCR-17-3678. Epub 2018 Jun 13.

PMID:
29898989
2.

Pathogenic germline MCM9 variants are rare in Australian Lynch-like syndrome patients.

Liu Q, Hesson LB, Nunez AC, Packham D, Hawkins NJ, Ward RL, Sloane MA.

Cancer Genet. 2016 Nov;209(11):497-500. doi: 10.1016/j.cancergen.2016.10.001. Epub 2016 Oct 11.

PMID:
27886675
3.

Allogeneic Mesenchymal Precursor Cells (MPC) in Diabetic Nephropathy: A Randomized, Placebo-controlled, Dose Escalation Study.

Packham DK, Fraser IR, Kerr PG, Segal KR.

EBioMedicine. 2016 Oct;12:263-269. doi: 10.1016/j.ebiom.2016.09.011. Epub 2016 Sep 17.

4.

Integrated Genetic, Epigenetic, and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumors.

Hesson LB, Ng B, Zarzour P, Srivastava S, Kwok CT, Packham D, Nunez AC, Beck D, Ryan R, Dower A, Ford CE, Pimanda JE, Sloane MA, Hawkins NJ, Bourke MJ, Wong JW, Ward RL.

Mol Cancer Res. 2016 Dec;14(12):1217-1228. Epub 2016 Sep 26.

5.

Successful treatment of cutaneous protothecosis with liposomal amphotericin and oral itraconazole.

McMullan B, Pollett S, Biswas C, Packham D.

Med Mycol Case Rep. 2016 Aug 3;12:21-3. doi: 10.1016/j.mmcr.2016.08.001. eCollection 2016 Jun.

6.

Pharmacodynamics and pharmacokinetics of sodium zirconium cyclosilicate [ZS-9] in the treatment of hyperkalemia.

Packham DK, Kosiborod M.

Expert Opin Drug Metab Toxicol. 2016 May;12(5):567-73. doi: 10.1517/17425255.2016.1164691. Epub 2016 Apr 5. Review.

PMID:
26998854
7.

Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr.

Thoms JA, Knezevic K, Liu JJ, Glaros EN, Thai T, Qiao Q, Campbell H, Packham D, Huang Y, Papathanasiou P, Tunningley R, Whittle B, Yeung AW, Chandrakanthan V, Hesson L, Chen V, Wong JW, Purton LE, Ward RL, Thomas SR, Pimanda JE.

Mol Cell Biol. 2016 Mar 31;36(8):1222-36. doi: 10.1128/MCB.01035-15. Print 2016 Apr.

8.

Individual long-term albuminuria exposure during angiotensin receptor blocker therapy is the optimal predictor for renal outcome.

Felix Kröpelin T, de Zeeuw D, Holtkamp FA, Packham DK, L Heerspink HJ.

Nephrol Dial Transplant. 2016 Sep;31(9):1471-7. doi: 10.1093/ndt/gfv429. Epub 2016 Jan 19.

PMID:
26790449
9.

A cryptic paracentric inversion of MSH2 exons 2-6 causes Lynch syndrome.

Liu Q, Hesson LB, Nunez AC, Packham D, Williams R, Ward RL, Sloane MA.

Carcinogenesis. 2016 Jan;37(1):10-17. doi: 10.1093/carcin/bgv154. Epub 2015 Oct 24.

PMID:
26498247
10.

Mosaic Epigenetic Inheritance as a Cause of Early-Onset Colorectal Cancer.

Sloane MA, Nunez AC, Packham D, Kwok CT, Suthers G, Hesson LB, Ward RL.

JAMA Oncol. 2015 Oct;1(7):953-7. doi: 10.1001/jamaoncol.2015.1484.

PMID:
26181641
11.

Potential New Agents for the Management of Hyperkalemia.

Packham DK, Kosiborod M.

Am J Cardiovasc Drugs. 2016 Feb;16(1):19-31. doi: 10.1007/s40256-015-0130-7. Review.

PMID:
26156040
12.

Modern technology and infectious diseases activity data: how can we use this for service planning?

Keighley C, Hamor P, Chen S, Watts MR, Douglas MW, Kok J, O'Sullivan M, Mitchell DH, Packham D, Sorrell TC, Iredell JR.

Intern Med J. 2015 Jun;45(6):688. doi: 10.1111/imj.12772. No abstract available.

PMID:
26059888
13.

New agents for hyperkalemia.

Packham DK, Rasmussen HS, Singh B.

N Engl J Med. 2015 Apr 16;372(16):1571-2. doi: 10.1056/NEJMc1501933. No abstract available.

PMID:
25884064
14.

Sodium zirconium cyclosilicate for urgent therapy of severe hyperkalemia.

Kosiborod M, Peacock WF, Packham DK.

N Engl J Med. 2015 Apr 16;372(16):1577-8. doi: 10.1056/NEJMc1500353. No abstract available.

15.

Delusional infestation: an Australian multicentre study of 23 consecutive cases.

Tran MM, Iredell JR, Packham DR, O'Sullivan MV, Hudson BJ.

Intern Med J. 2015 Apr;45(4):454-6. doi: 10.1111/imj.12719.

PMID:
25827513
16.

Lynch syndrome associated with two MLH1 promoter variants and allelic imbalance of MLH1 expression.

Hesson LB, Packham D, Kwok CT, Nunez AC, Ng B, Schmidt C, Fields M, Wong JW, Sloane MA, Ward RL.

Hum Mutat. 2015 Jun;36(6):622-30. doi: 10.1002/humu.22785. Epub 2015 Apr 17.

17.

Pyridoxamine dihydrochloride in diabetic nephropathy (PIONEER-CSG-17): lessons learned from a pilot study.

Dwyer JP, Greco BA, Umanath K, Packham D, Fox JW, Peterson R, Broome BR, Greene LE, Sika M, Lewis JB.

Nephron. 2015;129(1):22-8. doi: 10.1159/000369310. Epub 2014 Dec 16.

18.

Sodium zirconium cyclosilicate in hyperkalemia.

Packham DK, Rasmussen HS, Lavin PT, El-Shahawy MA, Roger SD, Block G, Qunibi W, Pergola P, Singh B.

N Engl J Med. 2015 Jan 15;372(3):222-31. doi: 10.1056/NEJMoa1411487. Epub 2014 Nov 21.

19.

Effect of sodium zirconium cyclosilicate on potassium lowering for 28 days among outpatients with hyperkalemia: the HARMONIZE randomized clinical trial.

Kosiborod M, Rasmussen HS, Lavin P, Qunibi WY, Spinowitz B, Packham D, Roger SD, Yang A, Lerma E, Singh B.

JAMA. 2014 Dec 3;312(21):2223-33. doi: 10.1001/jama.2014.15688. Erratum in: JAMA. 2015 Feb 3;313(5):526. Dosage error in text.

PMID:
25402495
20.

An exploratory study of the effectiveness of memory AIDS for older people living in supported accommodation.

Collerton D, Forster E, Packham D.

J Appl Gerontol. 2014 Dec;33(8):963-81. doi: 10.1177/0733464812456904. Epub 2012 Sep 17.

PMID:
25332304
21.

Ertapenem-associated psychosis and encephalopathy.

Oo Y, Packham D, Yau W, Munckhof WJ.

Intern Med J. 2014 Aug;44(8):817-9. doi: 10.1111/imj.12504. Review. No abstract available.

PMID:
25081048
22.

Mechanisms contributing to adverse cardiovascular events in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl.

Chin MP, Reisman SA, Bakris GL, O'Grady M, Linde PG, McCullough PA, Packham D, Vaziri ND, Ward KW, Warnock DG, Meyer CJ.

Am J Nephrol. 2014;39(6):499-508. doi: 10.1159/000362906. Epub 2014 Jun 3.

23.

Thermomyces lanuginosus infective endocarditis: Case report and a review of endocarditis due to uncommon moulds.

Sivagnanam S, Chen SC, Halliday C, Packham D.

Med Mycol Case Rep. 2013 Sep 18;2:152-5. doi: 10.1016/j.mmcr.2013.09.001. eCollection 2013 Sep 18.

24.

Residual proteinuria and eGFR predict progression of renal impairment within 2 years in type 2 diabetic patients with nephropathy who are receiving optimal treatment with angiotensin receptor blockers.

Ivory SE, Packham DK, Reutens AT, Wolfe R, Rohde RD, Lewis J, Atkins RC; Collaborative Study Group.

Nephrology (Carlton). 2013 Jul;18(7):516-24. doi: 10.1111/nep.12053.

PMID:
23506627
25.

Vitamin D reduces left atrial volume in patients with left ventricular hypertrophy and chronic kidney disease.

Tamez H, Zoccali C, Packham D, Wenger J, Bhan I, Appelbaum E, Pritchett Y, Chang Y, Agarwal R, Wanner C, Lloyd-Jones D, Cannata J, Thompson BT, Andress D, Zhang W, Singh B, Zehnder D, Pachika A, Manning WJ, Shah A, Solomon SD, Thadhani R.

Am Heart J. 2012 Dec;164(6):902-9.e2. doi: 10.1016/j.ahj.2012.09.018. Epub 2012 Oct 29.

PMID:
23194491
26.

Education and Imaging: gastrointestinal: outbreak; proctocolitis mimicking inflammatory bowel disease.

Nguyen V, Lee EY, Couldwell D, Packham D.

J Gastroenterol Hepatol. 2012 Nov;27(11):1760. doi: 10.1111/j.1440-1746.2012.07253.x. No abstract available.

PMID:
23106370
27.

Industry-university research contracts are damaging.

Packham D.

BMJ. 2012 Sep 18;345:e5978. doi: 10.1136/bmj.e5978. No abstract available.

PMID:
22990996
28.

A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines.

Hesson LB, Packham D, Pontzer E, Funchain P, Eng C, Ward RL.

Biol Proced Online. 2012 Apr 10;14(1):5. doi: 10.1186/1480-9222-14-5.

29.

Alopecia areata in two black Angus cows.

Valentine BA, Bildfell RJ, Packham D, Scott DW, Miller WH.

J Vet Diagn Invest. 2012 Mar;24(2):405-7. doi: 10.1177/1040638711435808. Epub 2012 Feb 7.

PMID:
22362539
30.

Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trial.

Thadhani R, Appelbaum E, Pritchett Y, Chang Y, Wenger J, Tamez H, Bhan I, Agarwal R, Zoccali C, Wanner C, Lloyd-Jones D, Cannata J, Thompson BT, Andress D, Zhang W, Packham D, Singh B, Zehnder D, Shah A, Pachika A, Manning WJ, Solomon SD.

JAMA. 2012 Feb 15;307(7):674-84. doi: 10.1001/jama.2012.120.

PMID:
22337679
31.

Relative incidence of ESRD versus cardiovascular mortality in proteinuric type 2 diabetes and nephropathy: results from the DIAMETRIC (Diabetes Mellitus Treatment for Renal Insufficiency Consortium) database.

Packham DK, Alves TP, Dwyer JP, Atkins R, de Zeeuw D, Cooper M, Shahinfar S, Lewis JB, Lambers Heerspink HJ.

Am J Kidney Dis. 2012 Jan;59(1):75-83. doi: 10.1053/j.ajkd.2011.09.017. Epub 2011 Nov 3.

PMID:
22051245
32.

Pyridorin in type 2 diabetic nephropathy.

Lewis EJ, Greene T, Spitalewiz S, Blumenthal S, Berl T, Hunsicker LG, Pohl MA, Rohde RD, Raz I, Yerushalmy Y, Yagil Y, Herskovits T, Atkins RC, Reutens AT, Packham DK, Lewis JB; Collaborative Study Group.

J Am Soc Nephrol. 2012 Jan;23(1):131-6. doi: 10.1681/ASN.2011030272. Epub 2011 Oct 27.

33.

Sulodexide fails to demonstrate renoprotection in overt type 2 diabetic nephropathy.

Packham DK, Wolfe R, Reutens AT, Berl T, Heerspink HL, Rohde R, Ivory S, Lewis J, Raz I, Wiegmann TB, Chan JC, de Zeeuw D, Lewis EJ, Atkins RC; Collaborative Study Group.

J Am Soc Nephrol. 2012 Jan;23(1):123-30. doi: 10.1681/ASN.2011040378. Epub 2011 Oct 27.

34.

Sulodexide for kidney protection in type 2 diabetes patients with microalbuminuria: a randomized controlled trial.

Lewis EJ, Lewis JB, Greene T, Hunsicker LG, Berl T, Pohl MA, de Zeeuw D, Heerspink HL, Rohde RD, Atkins RC, Reutens AT, Packham DK, Raz I; Collaborative Study Group.

Am J Kidney Dis. 2011 Nov;58(5):729-36. doi: 10.1053/j.ajkd.2011.06.020. Epub 2011 Aug 26. Erratum in: Am J Kidney Dis. 2012 Feb;59(2):318.

PMID:
21872376
35.

Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials.

Holtkamp FA, de Zeeuw D, de Graeff PA, Laverman GD, Berl T, Remuzzi G, Packham D, Lewis JB, Parving HH, Lambers Heerspink HJ.

Eur Heart J. 2011 Jun;32(12):1493-9. doi: 10.1093/eurheartj/ehr017. Epub 2011 Mar 18.

PMID:
21421598
36.

Proteinuria in type 2 diabetic patients with renal impairment: the changing face of diabetic nephropathy.

Packham DK, Ivory SE, Reutens AT, Wolfe R, Rohde R, Lambers Heerspink H, Dwyer JP, Atkins RC, Lewis J; Collaborative Study Group.

Nephron Clin Pract. 2011;118(4):c331-8. doi: 10.1159/000323139. Epub 2011 Feb 3.

PMID:
21293156
37.

Vitamin D receptor activation and left ventricular hypertrophy in advanced kidney disease.

Thadhani R, Appelbaum E, Chang Y, Pritchett Y, Bhan I, Agarwal R, Zoccali C, Wanner C, Lloyd-Jones D, Cannata J, Thompson T, Audhya P, Andress D, Zhang W, Ye J, Packham D, Singh B, Zehnder D, Manning WJ, Pachika A, Solomon SD.

Am J Nephrol. 2011;33(2):139-49. doi: 10.1159/000323551. Epub 2011 Jan 18.

PMID:
21242674
38.

De novo constitutional MLH1 epimutations confer early-onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one.

Goel A, Nguyen TP, Leung HC, Nagasaka T, Rhees J, Hotchkiss E, Arnold M, Banerji P, Koi M, Kwok CT, Packham D, Lipton L, Boland CR, Ward RL, Hitchins MP.

Int J Cancer. 2011 Feb 15;128(4):869-78. doi: 10.1002/ijc.25422.

39.

Progressive meningoencephalitis in a Sudanese immigrant.

Liu AP, Chou S, Gomes L, Ng T, Salisbury EL, Walker GL, Packham DR.

Med J Aust. 2010 Apr 5;192(7):413-6. No abstract available.

PMID:
20367592
40.

Effect of pravastatin on kidney function and urinary protein excretion in autosomal dominant polycystic kidney disease.

Fassett RG, Coombes JS, Packham D, Fairley KF, Kincaid-Smith P.

Scand J Urol Nephrol. 2010 Feb;44(1):56-61. doi: 10.3109/00365590903359908.

PMID:
20034362
41.

Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers.

Packham D, Ward RL, Ap Lin V, Hawkins NJ, Hitchins MP.

Diagn Mol Pathol. 2009 Jun;18(2):62-71. doi: 10.1097/PDM.0b013e318182af52.

PMID:
19430299
42.

Rationale for and study design of the sulodexide trials in Type 2 diabetic, hypertensive patients with microalbuminuria or overt nephropathy.

Lambers Heerspink HJ, Fowler MJ, Volgi J, Reutens AT, Klein I, Herskovits TA, Packham DK, Fraser IR, Schwartz SL, Abaterusso C, Lewis J; Collaborative Study Group.

Diabet Med. 2007 Nov;24(11):1290-5.

PMID:
17956455
43.

Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer.

Hitchins MP, Lin VA, Buckle A, Cheong K, Halani N, Ku S, Kwok CT, Packham D, Suter CM, Meagher A, Stirzaker C, Clark S, Hawkins NJ, Ward RL.

Cancer Res. 2007 Oct 1;67(19):9107-16.

44.
45.

Clinical images: Bazin's disease (erythema induratum).

Al-Mashaleh M, Packham D, Manolios N.

J Rheumatol. 2006 Jul;33(7):1415. No abstract available.

PMID:
16821277
46.

MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer.

Hitchins M, Williams R, Cheong K, Halani N, Lin VA, Packham D, Ku S, Buckle A, Hawkins N, Burn J, Gallinger S, Goldblatt J, Kirk J, Tomlinson I, Scott R, Spigelman A, Suter C, Martin D, Suthers G, Ward R.

Gastroenterology. 2005 Nov;129(5):1392-9.

PMID:
16285940
47.

Routine testing for mismatch repair deficiency in sporadic colorectal cancer is justified.

Ward RL, Turner J, Williams R, Pekarsky B, Packham D, Velickovic M, Meagher A, O'Connor T, Hawkins NJ.

J Pathol. 2005 Dec;207(4):377-84.

PMID:
16175654
48.

Systemic and vascular inflammation is elevated in early IgA and type 1 diabetic nephropathies and relates to vascular disease risk factors and renal function.

Nelson CL, Karschimkus CS, Dragicevic G, Packham DK, Wilson AM, O'Neal D, Becker GJ, Best JD, Jenkins AJ.

Nephrol Dial Transplant. 2005 Nov;20(11):2420-6. Epub 2005 Aug 22.

PMID:
16115854
49.

Thin basement membrane nephropathy in pregnancy.

Packham D.

Semin Nephrol. 2005 May;25(3):180-3.

PMID:
15880330
50.

Hematuria in thin basement membrane nephropathy.

Packham DK, Perkovic V, Savige J, Broome MR.

Semin Nephrol. 2005 May;25(3):146-8.

PMID:
15880324

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