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Items: 11


Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform.

Herzig E, Kim KC, Packard TA, Vardi N, Schwarzer R, Gramatica A, Deeks SG, Williams SR, Landgraf K, Killeen N, Martin DW, Weinberger LS, Greene WC.

Cell. 2019 Oct 31;179(4):880-894.e10. doi: 10.1016/j.cell.2019.10.002. Epub 2019 Oct 24.


Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes.

Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE.

Cytokine. 2018 Nov;111:373-381. doi: 10.1016/j.cyto.2018.10.001. Epub 2018 Oct 6.


Silencing of high-affinity insulin-reactive B lymphocytes by anergy and impact of the NOD genetic background in mice.

Smith MJ, Hinman RM, Getahun A, Kim S, Packard TA, Cambier JC.

Diabetologia. 2018 Dec;61(12):2621-2632. doi: 10.1007/s00125-018-4730-z. Epub 2018 Sep 25.


Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice.

Neudecker V, Brodsky KS, Clambey ET, Schmidt EP, Packard TA, Davenport B, Standiford TJ, Weng T, Fletcher AA, Barthel L, Masterson JC, Furuta GT, Cai C, Blackburn MR, Ginde AA, Graner MW, Janssen WJ, Zemans RL, Evans CM, Burnham EL, Homann D, Moss M, Kreth S, Zacharowski K, Henson PM, Eltzschig HK.

Sci Transl Med. 2017 Sep 20;9(408). pii: eaah5360. doi: 10.1126/scitranslmed.aah5360.


Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function.

Smith MJ, Packard TA, O'Neill SK, Hinman RM, Rihanek M, Gottlieb PA, Cambier JC.

J Vis Exp. 2017 Feb 16;(120). doi: 10.3791/55382.


B Cell Receptor Affinity for Insulin Dictates Autoantigen Acquisition and B Cell Functionality in Autoimmune Diabetes.

Packard TA, Smith MJ, Conrad FJ, Johnson SA, Getahun A, Lindsay RS, Hinman RM, Friedman RS, Thomas JW, Cambier JC.

J Clin Med. 2016 Nov 8;5(11). pii: E98.


Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients.

Smith MJ, Packard TA, O'Neill SK, Henry Dunand CJ, Huang M, Fitzgerald-Miller L, Stowell D, Hinman RM, Wilson PC, Gottlieb PA, Cambier JC.

Diabetes. 2015 May;64(5):1703-12. doi: 10.2337/db13-1798. Epub 2014 Dec 18.


B lymphocyte antigen receptor signaling: initiation, amplification, and regulation.

Packard TA, Cambier JC.

F1000Prime Rep. 2013 Oct 1;5:40. doi: 10.12703/P5-40. Review.


STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration.

Jin L, Getahun A, Knowles HM, Mogan J, Akerlund LJ, Packard TA, Perraud AL, Cambier JC.

J Immunol. 2013 Mar 15;190(6):2835-43. doi: 10.4049/jimmunol.1201788. Epub 2013 Feb 1.


COPD is associated with production of autoantibodies to a broad spectrum of self-antigens, correlative with disease phenotype.

Packard TA, Li QZ, Cosgrove GP, Bowler RP, Cambier JC.

Immunol Res. 2013 Mar;55(1-3):48-57. doi: 10.1007/s12026-012-8347-x.


B cell depletion therapy exacerbates murine primary biliary cirrhosis.

Dhirapong A, Lleo A, Yang GX, Tsuneyama K, Dunn R, Kehry M, Packard TA, Cambier JC, Liu FT, Lindor K, Coppel RL, Ansari AA, Gershwin ME.

Hepatology. 2011 Feb;53(2):527-35. doi: 10.1002/hep.24044. Epub 2010 Dec 28.

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