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Fusion tags to enhance heterologous protein expression.

Ki MR, Pack SP.

Appl Microbiol Biotechnol. 2020 Jan 28. doi: 10.1007/s00253-020-10402-8. [Epub ahead of print] Review.


Stabilized and Immobilized Carbonic Anhydrase on Electrospun Nanofibers for Enzymatic CO2 Conversion and Utilization in Expedited Microalgal Growth.

Jun SH, Yang J, Jeon H, Kim HS, Pack SP, Jin E, Kim J.

Environ Sci Technol. 2020 Jan 21;54(2):1223-1231. doi: 10.1021/acs.est.9b05284. Epub 2020 Jan 3.


Anaplastic Lymphoma Kinase Gene Rearrangement in Children and Young Adults With Mesothelioma.

Mian I, Abdullaev Z, Morrow B, Kaplan RN, Gao S, Miettinen M, Schrump DS, Zgonc V, Wei JS, Khan J, Pack S, Hassan R.

J Thorac Oncol. 2019 Nov 26. pii: S1556-0864(19)33665-2. doi: 10.1016/j.jtho.2019.11.011. [Epub ahead of print]


Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups.

Egan C, Nicolae A, Lack J, Chung HJ, Skarshaug S, Pham TA, Navarro W, Abdullaev Z, Aguilera NS, Xi L, Pack S, Pittaluga S, Jaffe ES, Raffeld M.

Haematologica. 2019 Aug 22. pii: haematol.2019.230375. doi: 10.3324/haematol.2019.230375. [Epub ahead of print]


ALK-positive histiocytosis with KIF5B-ALK fusion in an adult female.

Gupta GK, Xi L, Pack SD, Jones JB, Pittaluga S, Raffeld M, Jaffe ES.

Haematologica. 2019 Nov;104(11):e534-e536. doi: 10.3324/haematol.2019.230094. Epub 2019 Aug 1. No abstract available.


Nonvascularized Bone Grafts for Reconstruction of Segmental Mandibular Defects: Is Length of Graft a Factor of Success?

Marechek A, AlShare A, Pack S, Demko C, Quereshy FA, Baur D.

J Oral Maxillofac Surg. 2019 Dec;77(12):2557-2566. doi: 10.1016/j.joms.2019.05.008. Epub 2019 May 25.


The uncertain future of protected lands and waters.

Golden Kroner RE, Qin S, Cook CN, Krithivasan R, Pack SM, Bonilla OD, Cort-Kansinally KA, Coutinho B, Feng M, Martínez Garcia MI, He Y, Kennedy CJ, Lebreton C, Ledezma JC, Lovejoy TE, Luther DA, Parmanand Y, Ruíz-Agudelo CA, Yerena E, Morón Zambrano V, Mascia MB.

Science. 2019 May 31;364(6443):881-886. doi: 10.1126/science.aau5525.


Direct immobilization and recovery of recombinant proteins from cell lysates by using EctP1-peptide as a short fusion tag for silica and titania supports.

Kim JK, Abdelhamid MAA, Pack SP.

Int J Biol Macromol. 2019 Aug 15;135:969-977. doi: 10.1016/j.ijbiomac.2019.05.105. Epub 2019 May 24.


CD30+ large B cell lymphoma with anaplastic features and complete loss of B cell marker expression arising from follicular lymphoma.

Raess PW, Wang HW, Pack SD, Jaffe ES.

Histopathology. 2019 Oct;75(4):602-605. doi: 10.1111/his.13919. Epub 2019 Aug 22. No abstract available.


Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3.

Abd El-Hafeez AA, Khalifa HO, Mahdy EAM, Sharma V, Hosoi T, Ghosh P, Ozawa K, Montano MM, Fujimura T, Ibrahim ARN, Abdelhamid MAA, Pack SP, Shouman SA, Kawamoto S.

Pharmacol Rep. 2019 Apr;71(2):289-298. doi: 10.1016/j.pharep.2019.01.001. Epub 2019 Jan 7.


Melanoma With Loss of BAP1 Expression in Patients With No Family History of BAP1-Associated Cancer Susceptibility Syndrome: A Case Series.

Aung PP, Nagarajan P, Tetzlaff MT, Curry JL, Tang G, Abdullaev Z, Pack SD, Ivan D, Prieto VG, Torres-Cabala CA.

Am J Dermatopathol. 2019 Mar;41(3):167-179. doi: 10.1097/DAD.0000000000001217.


The NT11, a novel fusion tag for enhancing protein expression in Escherichia coli.

Nguyen TKM, Ki MR, Son RG, Pack SP.

Appl Microbiol Biotechnol. 2019 Mar;103(5):2205-2216. doi: 10.1007/s00253-018-09595-w. Epub 2019 Jan 4.


Self-encapsulation and controlled release of recombinant proteins using novel silica-forming peptides as fusion linkers.

Abdelhamid MAA, Yeo KB, Ki MR, Pack SP.

Int J Biol Macromol. 2019 Mar 15;125:1175-1183. doi: 10.1016/j.ijbiomac.2018.12.160. Epub 2018 Dec 18.


Decreased Expression of Sphingosine-1-Phosphate Receptor 1 in the Blood Leukocyte of Rheumatoid Arthritis Patients.

Choi HS, Kim KH, Jin S, Kim J, Yoo I, Pack SP, Ha UH, Park TW, Choi SA, Yuk SH, Kang SW, Jung YW.

Immune Netw. 2018 Oct 26;18(5):e39. doi: 10.4110/in.2018.18.e39. eCollection 2018 Oct.


Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System.

Vizcardo R, Klemen ND, Islam SMR, Gurusamy D, Tamaoki N, Yamada D, Koseki H, Kidder BL, Yu Z, Jia L, Henning AN, Good ML, Bosch-Marce M, Maeda T, Liu C, Abdullaev Z, Pack S, Palmer DC, Stroncek DF, Ito F, Flomerfelt FA, Kruhlak MJ, Restifo NP.

Cell Rep. 2018 Mar 20;22(12):3175-3190. doi: 10.1016/j.celrep.2018.02.087.


A novel splicing site IRP1 somatic mutation in a patient with pheochromocytoma and JAK2V617F positive polycythemia vera: a case report.

Pang Y, Gupta G, Yang C, Wang H, Huynh TT, Abdullaev Z, Pack SD, Percy MJ, Lappin TRJ, Zhuang Z, Pacak K.

BMC Cancer. 2018 Mar 13;18(1):286. doi: 10.1186/s12885-018-4127-x.


Melanoma in patients with GATA2 deficiency.

Nguyen J, Alexander T, Jiang H, Hill N, Abdullaev Z, Pack SD, Hsu AP, Holland SM, Hickstein DD, Engels EA, Brownell I.

Pigment Cell Melanoma Res. 2018 Mar;31(2):337-340. doi: 10.1111/pcmr.12671. Epub 2017 Dec 10.


Respiratory Therapist-Managed Arterial Catheter Insertion and Maintenance Program: Experience in a Non-Teaching Community Hospital.

Pack S, Hahn PY, Stoller JK, Mummadi SR.

Respir Care. 2017 Dec;62(12):1520-1524. doi: 10.4187/respcare.05486. Epub 2017 Oct 3.


Correlation between ERG Fusion Protein and Androgen Receptor Expression by Immunohistochemistry in Prostate, Possible Role in Diagnosis and Therapy.

Navaei AH, Walter BA, Moreno V, Pack SD, Pinto P, Merino MJ.

J Cancer. 2017 Aug 5;8(13):2604-2613. doi: 10.7150/jca.16751. eCollection 2017.


PD-1 Blockade in Mediastinal Gray-Zone Lymphoma.

Melani C, Major A, Schowinsky J, Roschewski M, Pittaluga S, Jaffe ES, Pack SD, Abdullaev Z, Ahlman MA, Kwak JJ, Morgan R, Rabinovitch R, Pan Z, Haverkos BM, Gutman JA, Pollyea DA, Smith CA, Wilson WH, Kamdar M.

N Engl J Med. 2017 Jul 6;377(1):89-91. doi: 10.1056/NEJMc1704767. No abstract available.


MYC gene rearrangement in diffuse large B-cell lymphoma does not confer a worse prognosis following dose-adjusted EPOCH-R.

Lai C, Roschewski M, Melani C, Pittaluga S, Shovlin M, Steinberg SM, Dunleavy K, Pack S, Jaffe ES, Wilson WH.

Leuk Lymphoma. 2018 Feb;59(2):505-508. doi: 10.1080/10428194.2017.1339882. Epub 2017 Jun 22. No abstract available.


In-depth compositional analysis of water-soluble and -insoluble organic substances in fine (PM2.5) airborne particles using ultra-high-resolution 15T FT-ICR MS and GC×GC-TOFMS.

Choi JH, Ryu J, Jeon S, Seo J, Yang YH, Pack SP, Choung S, Jang KS.

Environ Pollut. 2017 Jun;225:329-337. doi: 10.1016/j.envpol.2017.02.058. Epub 2017 Mar 6.


Gas Diffusion Barriers Prepared by Spatial Atmospheric Pressure Plasma Enhanced ALD.

Hoffmann L, Theirich D, Pack S, Kocak F, Schlamm D, Hasselmann T, Fahl H, Räupke A, Gargouri H, Riedl T.

ACS Appl Mater Interfaces. 2017 Feb 1;9(4):4171-4176. doi: 10.1021/acsami.6b13380. Epub 2017 Jan 23.


Increased incorporation of gaseous CO2 into succinate by Escherichia coli overexpressing carbonic anhydrase and phosphoenolpyruvate carboxylase genes.

Park S, Lee JU, Cho S, Kim H, Oh HB, Pack SP, Lee J.

J Biotechnol. 2017 Jan 10;241:101-107. doi: 10.1016/j.jbiotec.2016.11.027. Epub 2016 Nov 28.


Genomic profiling of multiple sequentially acquired tumor metastatic sites from an "exceptional responder" lung adenocarcinoma patient reveals extensive genomic heterogeneity and novel somatic variants driving treatment response.

Biswas R, Gao S, Cultraro CM, Maity TK, Venugopalan A, Abdullaev Z, Shaytan AK, Carter CA, Thomas A, Rajan A, Song Y, Pitts S, Chen K, Bass S, Boland J, Hanada KI, Chen J, Meltzer PS, Panchenko AR, Yang JC, Pack S, Giaccone G, Schrump DS, Khan J, Guha U.

Cold Spring Harb Mol Case Stud. 2016 Nov;2(6):a001263.


Expression and characterization of a codon-optimized alkaline-stable carbonic anhydrase from Aliivibrio salmonicida for CO2 sequestration applications.

Jun SY, Kim SH, Kanth BK, Lee J, Pack SP.

Bioprocess Biosyst Eng. 2017 Mar;40(3):413-421. doi: 10.1007/s00449-016-1709-3. Epub 2016 Nov 28.


Osteosarcoma of the Mandible Arising in Fibrous Dysplasia-A Case Report.

Pack SE, Al Share AA, Quereshy FA, Baur DA.

J Oral Maxillofac Surg. 2016 Nov;74(11):2229.e1-2229.e4. doi: 10.1016/j.joms.2016.06.174. Epub 2016 Jun 21.


"I think I became a swimmer rather than just someone with a disability swimming up and down:" paralympic athletes perceptions of self and identity development.

Pack S, Kelly S, Arvinen-Barrow M.

Disabil Rehabil. 2017 Oct;39(20):2063-2070. doi: 10.1080/09638288.2016.1217074. Epub 2016 Sep 27.


Transconjunctival Lower Blepharoplasty.

Pack S, Quereshy FA, Altay MA, Baur DA.

Atlas Oral Maxillofac Surg Clin North Am. 2016 Sep;24(2):147-51. doi: 10.1016/j.cxom.2016.05.011. Epub 2016 Jun 23. Review.


A cold-adapted tyrosinase with an abnormally high monophenolase/diphenolase activity ratio originating from the marine archaeon Candidatus Nitrosopumilus koreensis.

Kim H, Yeon YJ, Choi YR, Song W, Pack SP, Choi YS.

Biotechnol Lett. 2016 Sep;38(9):1535-42. doi: 10.1007/s10529-016-2125-0. Epub 2016 May 19.


Recombinant production of a shell matrix protein in Escherichia coli and its application to the biomimetic synthesis of spherulitic calcite crystals.

Song W, Bahn SY, Cha HJ, Pack SP, Choi YS.

Biotechnol Lett. 2016 May;38(5):809-16. doi: 10.1007/s10529-016-2039-x. Epub 2016 Jan 13.


Highly effective detection of inflamed cells using a modified bradykinin ligand labeled with FITC fluorescence.

Yeo KB, Kim HB, Choi YS, Pack SP.

Enzyme Microb Technol. 2016 Jan;82:191-196. doi: 10.1016/j.enzmictec.2015.10.008. Epub 2015 Nov 1.


High expression and biosilica encapsulation of alkaline-active carbonic anhydrase for CO2 sequestration system development.

Min KH, Son RG, Ki MR, Choi YS, Pack SP.

Chemosphere. 2016 Jan;143:128-34. doi: 10.1016/j.chemosphere.2015.07.020. Epub 2015 Jul 21.


Highly-efficient T4 DNA ligase-based SNP analysis using a ligation fragment containing a modified nucleobase at the end.

Jang EK, Yang M, Pack SP.

Chem Commun (Camb). 2015 Aug 25;51(66):13090-3. doi: 10.1039/c5cc03761a.


Characterization of Phosphoenolpyruvate Carboxylase from Oceanimonas smirnovii in Escherichia coli.

Park S, Lee W, Kim H, Pack SP, Lee J.

Appl Biochem Biotechnol. 2015 Sep;177(1):217-25. doi: 10.1007/s12010-015-1739-3. Epub 2015 Jul 5.


High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis.

Thomas A, Chen Y, Steinberg SM, Luo J, Pack S, Raffeld M, Abdullaev Z, Alewine C, Rajan A, Giaccone G, Pastan I, Miettinen M, Hassan R.

Oncotarget. 2015 May 10;6(13):11694-703.


Changes of gene expression of Gal3, Hsp27, Lcn2, and Timp1 in rat substantia nigra following medial forebrain bundle transection using a candidate gene microarray.

Choy YJ, Hong SY, Pack SJ, Woo RS, Baik TK, Song DY.

J Chem Neuroanat. 2015 Jul-Sep;66-67:10-8. doi: 10.1016/j.jchemneu.2015.03.003. Epub 2015 Apr 6.


CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma.

Olanich ME, Sun W, Hewitt SM, Abdullaev Z, Pack SD, Barr FG.

Clin Cancer Res. 2015 Nov 1;21(21):4947-59. doi: 10.1158/1078-0432.CCR-14-2955. Epub 2015 Mar 25.


Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial.

Lopez-Chavez A, Thomas A, Rajan A, Raffeld M, Morrow B, Kelly R, Carter CA, Guha U, Killian K, Lau CC, Abdullaev Z, Xi L, Pack S, Meltzer PS, Corless CL, Sandler A, Beadling C, Warrick A, Liewehr DJ, Steinberg SM, Berman A, Doyle A, Szabo E, Wang Y, Giaccone G.

J Clin Oncol. 2015 Mar 20;33(9):1000-7. doi: 10.1200/JCO.2014.58.2007. Epub 2015 Feb 9.


An exploration of sports rehabilitators' and athletic rehabilitation therapists' views on fear of reinjury after anterior cruciate ligament reconstruction.

McVeigh F, Pack SM.

J Sport Rehabil. 2015 May;24(2):140-50. doi: 10-1123/jsr.2014-0127. Epub 2015 Jan 5.


Enhanced free fatty acid production by codon-optimized Lactococcus lactis acyl-ACP thioesterase gene expression in Escherichia coli using crude glycerol.

Lee S, Park S, Park C, Pack SP, Lee J.

Enzyme Microb Technol. 2014 Dec;67:8-16. doi: 10.1016/j.enzmictec.2014.08.004. Epub 2014 Aug 23.


Multifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy.

Yang AI, Khawaja AM, Ballester-Fuentes L, Pack SD, Abdullaev Z, Patronas NJ, Inati SK, Theodore WH, Quezado MM, Zaghloul KA.

Epileptic Disord. 2014 Sep;16(3):328-32. doi: 10.1684/epd.2014.0680.


Malignant round cell tumor of bone with EWSR1-NFATC2 gene fusion.

Sadri N, Barroeta J, Pack SD, Abdullaev Z, Chatterjee B, Puthiyaveettil R, Brooks JS, Barr FG, Zhang PJ.

Virchows Arch. 2014 Aug;465(2):233-9. doi: 10.1007/s00428-014-1613-7. Epub 2014 Jul 4.


Frequent STAT5B mutations in γδ hepatosplenic T-cell lymphomas.

Nicolae A, Xi L, Pittaluga S, Abdullaev Z, Pack SD, Chen J, Waldmann TA, Jaffe ES, Raffeld M.

Leukemia. 2014 Nov;28(11):2244-8. doi: 10.1038/leu.2014.200. Epub 2014 Jun 20. No abstract available.


Von hippel-lindau disease associated pulmonary carcinoid with cranial metastasis.

Zhang C, Yang AI, Vasconcelos L, Moon S, Yang C, Nesvick CL, Saidkhodjaeva L, Abdullaev Z, Pack SD, Ghosh A, Chittiboina P, Heiss JD, Zhuang Z, Quezado MM, Zaghloul KA.

J Clin Endocrinol Metab. 2014 Aug;99(8):2633-6. doi: 10.1210/jc.2014-1732. Epub 2014 May 30.


Characterization of fibroblast growth factor receptor 1 in small-cell lung cancer.

Thomas A, Lee JH, Abdullaev Z, Park KS, Pineda M, Saidkhodjaeva L, Miettinen M, Wang Y, Pack SD, Giaccone G.

J Thorac Oncol. 2014 Apr;9(4):567-71. doi: 10.1097/JTO.0000000000000089.


Primary subcutaneous spindle cell Ewing sarcoma with strong S100 expression and EWSR1-FLI1 fusion: a case report.

Arnold MA, Ballester LY, Pack SD, Abdullaev Z, Merchant M, Tsokos MG.

Pediatr Dev Pathol. 2014 Jul-Aug;17(4):302-7. doi: 10.2350/14-03-1454-CR.1. Epub 2014 Apr 15.


Two Cases of Spinal, Extraosseous, Intradural Ewing's sarcoma/Peripheral Neuroectodermal Tumor: Radiologic, Pathologic, and Molecular Analysis.

Mardekian SK, Gandhe A, Miettinen M, Pack S, Curtis MT, Abdullaev Z.

J Clin Imaging Sci. 2014 Jan 30;4:6. doi: 10.4103/2156-7514.126050. eCollection 2014.


Tumor derived vasculogenesis in von Hippel-Lindau disease-associated tumors.

Zhuang Z, Frerich JM, Huntoon K, Yang C, Merrill MJ, Abdullaev Z, Pack SD, Shively SB, Stamp G, Lonser RR.

Sci Rep. 2014 Feb 17;4:4102. doi: 10.1038/srep04102.

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