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Items: 1 to 50 of 147

1.

A New Era of CMGH.

Kaestner KH, Pack M.

Cell Mol Gastroenterol Hepatol. 2019;8(3):527. doi: 10.1016/j.jcmgh.2019.08.012. Epub 2019 Sep 10. No abstract available.

2.

The effect of particle wettability on the stick-slip motion of the contact line.

Kim DO, Pack M, Rokoni A, Kaneelil P, Sun Y.

Soft Matter. 2018 Dec 5;14(47):9599-9608. doi: 10.1039/c8sm02129e.

PMID:
30457136
3.

Contact Line Instability Caused by Air Rim Formation under Nonsplashing Droplets.

Pack M, Kaneelil P, Kim H, Sun Y.

Langmuir. 2018 May 1;34(17):4962-4969. doi: 10.1021/acs.langmuir.8b01082. Epub 2018 Apr 19.

PMID:
29620373
4.

Synthesis and Structure-Activity Relationship Study of Biliatresone, a Plant Isoflavonoid That Causes Biliary Atresia.

Estrada MA, Zhao X, Lorent K, Kriegermeier A, Nagao SA, Berritt S, Wells RG, Pack M, Winkler JD.

ACS Med Chem Lett. 2017 Dec 14;9(1):61-64. doi: 10.1021/acsmedchemlett.7b00479. eCollection 2018 Jan 11.

5.

Protective Efficacy of Broadly Neutralizing Antibodies with Incomplete Neutralization Activity against Simian-Human Immunodeficiency Virus in Rhesus Monkeys.

Julg B, Sok D, Schmidt SD, Abbink P, Newman RM, Broge T, Linde C, Nkolola J, Le K, Su D, Torabi J, Pack M, Pegu A, Allen TM, Mascola JR, Burton DR, Barouch DH.

J Virol. 2017 Sep 27;91(20). pii: e01187-17. doi: 10.1128/JVI.01187-17. Print 2017 Oct 15.

6.

Dengue Virus Evades AAV-Mediated Neutralizing Antibody Prophylaxis in Rhesus Monkeys.

Magnani DM, Ricciardi MJ, Bailey VK, Gutman MJ, Pedreño-Lopez N, Silveira CGT, Maxwell HS, Domingues A, Gonzalez-Nieto L, Su Q, Newman RM, Pack M, Martins MA, Martinez-Navio JM, Fuchs SP, Rakasz EG, Allen TM, Whitehead SS, Burton DR, Gao G, Desrosiers RC, Kallas EG, Watkins DI.

Mol Ther. 2017 Oct 4;25(10):2323-2331. doi: 10.1016/j.ymthe.2017.06.020. Epub 2017 Jul 24.

7.

Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease.

Ko YA, Yi H, Qiu C, Huang S, Park J, Ledo N, Köttgen A, Li H, Rader DJ, Pack MA, Brown CD, Susztak K.

Am J Hum Genet. 2017 Jun 1;100(6):940-953. doi: 10.1016/j.ajhg.2017.05.004.

8.

Failure mechanisms of air entrainment in drop impact on lubricated surfaces.

Pack M, Hu H, Kim D, Zheng Z, Stone HA, Sun Y.

Soft Matter. 2017 Mar 22;13(12):2402-2409. doi: 10.1039/c7sm00117g.

PMID:
28287231
9.

Modeling intestinal disorders using zebrafish.

Zhao X, Pack M.

Methods Cell Biol. 2017;138:241-270. doi: 10.1016/bs.mcb.2016.11.006. Epub 2017 Jan 7. Review.

PMID:
28129846
10.

The RNA polymerase III subunit Polr3b is required for the maintenance of small intestinal crypts in mice.

Kieckhaefer J, Lukovac S, Ye DZ, Lee D, Beetler DJ, Pack M, Kaestner KH.

Cell Mol Gastroenterol Hepatol. 2016 Nov;2(6):783-795. doi: 10.1016/j.jcmgh.2016.08.003.

11.

Deposition of Colloidal Drops Containing Ellipsoidal Particles: Competition between Capillary and Hydrodynamic Forces.

Kim DO, Pack M, Hu H, Kim H, Sun Y.

Langmuir. 2016 Nov 15;32(45):11899-11906. Epub 2016 Nov 4.

PMID:
27788012
12.

Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish.

Zhao X, Lorent K, Wilkins BJ, Marchione DM, Gillespie K, Waisbourd-Zinman O, So J, Koo KA, Shin D, Porter JR, Wells RG, Blair I, Pack M.

Hepatology. 2016 Sep;64(3):894-907. doi: 10.1002/hep.28603. Epub 2016 Jun 11.

13.

The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17.

Waisbourd-Zinman O, Koh H, Tsai S, Lavrut PM, Dang C, Zhao X, Pack M, Cave J, Hawes M, Koo KA, Porter JR, Wells RG.

Hepatology. 2016 Sep;64(3):880-93. doi: 10.1002/hep.28599. Epub 2016 May 20.

14.

Graded effects of unregulated smooth muscle myosin on intestinal architecture, intestinal motility and vascular function in zebrafish.

Abrams J, Einhorn Z, Seiler C, Zong AB, Sweeney HL, Pack M.

Dis Model Mech. 2016 May 1;9(5):529-40. doi: 10.1242/dmm.023309. Epub 2016 Feb 18.

15.

Reactivity of Biliatresone, a Natural Biliary Toxin, with Glutathione, Histamine, and Amino Acids.

Koo KA, Waisbourd-Zinman O, Wells RG, Pack M, Porter JR.

Chem Res Toxicol. 2016 Feb 15;29(2):142-9. doi: 10.1021/acs.chemrestox.5b00308. Epub 2016 Jan 13.

16.

Biliatresone, a Reactive Natural Toxin from Dysphania glomulifera and D. littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone.

Koo KA, Lorent K, Gong W, Windsor P, Whittaker SJ, Pack M, Wells RG, Porter JR.

Chem Res Toxicol. 2015 Aug 17;28(8):1519-21. doi: 10.1021/acs.chemrestox.5b00227. Epub 2015 Jul 20.

17.

Colloidal Drop Deposition on Porous Substrates: Competition among Particle Motion, Evaporation, and Infiltration.

Pack M, Hu H, Kim DO, Yang X, Sun Y.

Langmuir. 2015 Jul 28;31(29):7953-61. doi: 10.1021/acs.langmuir.5b01846. Epub 2015 Jul 14.

PMID:
26132211
18.

Identification of a plant isoflavonoid that causes biliary atresia.

Lorent K, Gong W, Koo KA, Waisbourd-Zinman O, Karjoo S, Zhao X, Sealy I, Kettleborough RN, Stemple DL, Windsor PA, Whittaker SJ, Porter JR, Wells RG, Pack M.

Sci Transl Med. 2015 May 6;7(286):286ra67. doi: 10.1126/scitranslmed.aaa1652.

19.

IBD. Fishing for missing heritability in IBD.

Pack M.

Nat Rev Gastroenterol Hepatol. 2015 Jun;12(6):318-20. doi: 10.1038/nrgastro.2015.72. Epub 2015 May 5.

PMID:
25942704
20.

Efficacy and safety of CDX-301, recombinant human Flt3L, at expanding dendritic cells and hematopoietic stem cells in healthy human volunteers.

Anandasabapathy N, Breton G, Hurley A, Caskey M, Trumpfheller C, Sarma P, Pring J, Pack M, Buckley N, Matei I, Lyden D, Green J, Hawthorne T, Marsh HC, Yellin M, Davis T, Keler T, Schlesinger SJ.

Bone Marrow Transplant. 2015 Jul;50(7):924-30. doi: 10.1038/bmt.2015.74. Epub 2015 Apr 27.

21.
22.

p53-mediated biliary defects caused by knockdown of cirh1a, the zebrafish homolog of the gene responsible for North American Indian Childhood Cirrhosis.

Wilkins BJ, Lorent K, Matthews RP, Pack M.

PLoS One. 2013 Oct 11;8(10):e77670. doi: 10.1371/journal.pone.0077670. eCollection 2013.

23.

Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish.

Valvezan AJ, Huang J, Lengner CJ, Pack M, Klein PS.

Dis Model Mech. 2014 Jan;7(1):63-71. doi: 10.1242/dmm.012625. Epub 2013 Oct 2.

24.

Visualizing change over time using dynamic hierarchies: TreeVersity2 and the StemView.

Guerra-Gómez J, Pack ML, Plaisant C, Shneiderman B.

IEEE Trans Vis Comput Graph. 2013 Dec;19(12):2566-75. doi: 10.1109/TVCG.2013.231.

PMID:
24051823
25.

Zebrafish models of human liver development and disease.

Wilkins BJ, Pack M.

Compr Physiol. 2013 Jul;3(3):1213-30. doi: 10.1002/cphy.c120021. Review.

26.

The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development.

Rawnsley DR, Xiao J, Lee JS, Liu X, Mericko-Ishizuka P, Kumar V, He J, Basu A, Lu M, Lynn FC, Pack M, Gasa R, Kahn ML.

J Biol Chem. 2013 Aug 23;288(34):24429-40. doi: 10.1074/jbc.M113.463083. Epub 2013 Jul 8.

27.

CD141+ dendritic cells produce prominent amounts of IFN-α after dsRNA recognition and can be targeted via DEC-205 in humanized mice.

Meixlsperger S, Leung CS, Rämer PC, Pack M, Vanoaica LD, Breton G, Pascolo S, Salazar AM, Dzionek A, Schmitz J, Steinman RM, Münz C.

Blood. 2013 Jun 20;121(25):5034-44. doi: 10.1182/blood-2012-12-473413. Epub 2013 Mar 12.

28.

SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors.

Forsyth T, Kearney PC, Kim BG, Johnson HW, Aay N, Arcalas A, Brown DS, Chan V, Chen J, Du H, Epshteyn S, Galan AA, Huynh TP, Ibrahim MA, Kane B, Koltun ES, Mann G, Meyr LE, Lee MS, Lewis GL, Noguchi RT, Pack M, Ridgway BH, Shi X, Takeuchi CS, Zu P, Leahy JW, Nuss JM, Aoyama R, Engst S, Gendreau SB, Kassees R, Li J, Lin SH, Martini JF, Stout T, Tong P, Woolfrey J, Zhang W, Yu P.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7653-8. doi: 10.1016/j.bmcl.2012.10.007. Epub 2012 Oct 16.

PMID:
23127890
29.

Smooth muscle tension induces invasive remodeling of the zebrafish intestine.

Seiler C, Davuluri G, Abrams J, Byfield FJ, Janmey PA, Pack M.

PLoS Biol. 2012;10(9):e1001386. doi: 10.1371/journal.pbio.1001386. Epub 2012 Sep 4.

30.

Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90.

Bussenius J, Blazey CM, Aay N, Anand NK, Arcalas A, Baik T, Bowles OJ, Buhr CA, Costanzo S, Curtis JK, DeFina SC, Dubenko L, Heuer TS, Huang P, Jaeger C, Joshi A, Kennedy AR, Kim AI, Lara K, Lee J, Li J, Lougheed JC, Ma S, Malek S, Manalo JC, Martini JF, McGrath G, Nicoll M, Nuss JM, Pack M, Peto CJ, Tsang TH, Wang L, Womble SW, Yakes M, Zhang W, Rice KD.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5396-404. doi: 10.1016/j.bmcl.2012.07.052. Epub 2012 Jul 21.

PMID:
22877636
31.

Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid.

Walters JW, Anderson JL, Bittman R, Pack M, Farber SA.

Chem Biol. 2012 Jul 27;19(7):913-25. doi: 10.1016/j.chembiol.2012.05.018. Epub 2012 Jun 28. Erratum in: Chem Biol. 2012 Aug 24;19(8):1073. Dosage error in article text. Retraction in: Chem Biol. 2015 Sep 17;22(9):1283.

32.

The design, synthesis, and biological evaluation of PIM kinase inhibitors.

Tsuhako AL, Brown DS, Koltun ES, Aay N, Arcalas A, Chan V, Du H, Engst S, Franzini M, Galan A, Huang P, Johnston S, Kane B, Kim MH, Laird AD, Lin R, Mock L, Ngan I, Pack M, Stott G, Stout TJ, Yu P, Zaharia C, Zhang W, Zhou P, Nuss JM, Kearney PC, Xu W.

Bioorg Med Chem Lett. 2012 Jun 1;22(11):3732-8. doi: 10.1016/j.bmcl.2012.04.025. Epub 2012 Apr 11.

PMID:
22542012
33.

Smooth muscle caldesmon modulates peristalsis in the wild type and non-innervated zebrafish intestine.

Abrams J, Davuluri G, Seiler C, Pack M.

Neurogastroenterol Motil. 2012 Mar;24(3):288-99. doi: 10.1111/j.1365-2982.2011.01844.x.

34.

Generation of anti-human DEC205/CD205 monoclonal antibodies that recognize epitopes conserved in different mammals.

Park CG, Rodriguez A, Ueta H, Lee H, Pack M, Matsuno K, Steinman RM.

J Immunol Methods. 2012 Mar 30;377(1-2):15-22. doi: 10.1016/j.jim.2011.12.009. Epub 2012 Jan 16.

35.

Review article: People who present on multiple occasions to emergency departments.

Nelson K, Connor M, Wensley C, Moss C, Pack M, Hussey T.

Emerg Med Australas. 2011 Oct;23(5):532-40. doi: 10.1111/j.1742-6723.2011.01449.x. Epub 2011 Jun 27. Review.

PMID:
21995467
36.

DNA hypomethylation causes bile duct defects in zebrafish and is a distinguishing feature of infantile biliary atresia.

Matthews RP, Eauclaire SF, Mugnier M, Lorent K, Cui S, Ross MM, Zhang Z, Russo P, Pack M.

Hepatology. 2011 Mar;53(3):905-14. doi: 10.1002/hep.24106. Epub 2011 Feb 11.

37.

The nuclear pore complex protein Elys is required for genome stability in mouse intestinal epithelial progenitor cells.

Gao N, Davuluri G, Gong W, Seiler C, Lorent K, Furth EE, Kaestner KH, Pack M.

Gastroenterology. 2011 May;140(5):1547-55.e10. doi: 10.1053/j.gastro.2011.01.048. Epub 2011 Mar 21.

38.

Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas.

Cheong C, Matos I, Choi JH, Dandamudi DB, Shrestha E, Longhi MP, Jeffrey KL, Anthony RM, Kluger C, Nchinda G, Koh H, Rodriguez A, Idoyaga J, Pack M, Velinzon K, Park CG, Steinman RM.

Cell. 2010 Oct 29;143(3):416-29. doi: 10.1016/j.cell.2010.09.039.

39.

Transgenic labeling of the zebrafish pronephric duct and tubules using a promoter from the enpep gene.

Seiler C, Pack M.

Gene Expr Patterns. 2011 Jan-Feb;11(1-2):118-21. doi: 10.1016/j.gep.2010.10.002. Epub 2010 Oct 20.

40.

Characterization of zebrafish intestinal smooth muscle development using a novel sm22α-b promoter.

Seiler C, Abrams J, Pack M.

Dev Dyn. 2010 Nov;239(11):2806-12. doi: 10.1002/dvdy.22420.

41.

The methane cycle in ferruginous Lake Matano.

Crowe SA, Katsev S, Leslie K, Sturm A, Magen C, Nomosatryo S, Pack MA, Kessler JD, Reeburgh WS, Roberts JA, González L, Douglas Haffner G, Mucci A, Sundby B, Fowle DA.

Geobiology. 2011 Jan;9(1):61-78. doi: 10.1111/j.1472-4669.2010.00257.x. Epub 2010 Sep 20.

42.

Identification of novel inhibitors of dietary lipid absorption using zebrafish.

Clifton JD, Lucumi E, Myers MC, Napper A, Hama K, Farber SA, Smith AB 3rd, Huryn DM, Diamond SL, Pack M.

PLoS One. 2010 Aug 25;5(8):e12386. doi: 10.1371/journal.pone.0012386.

43.

Improved cellular and humoral immune responses in vivo following targeting of HIV Gag to dendritic cells within human anti-human DEC205 monoclonal antibody.

Cheong C, Choi JH, Vitale L, He LZ, Trumpfheller C, Bozzacco L, Do Y, Nchinda G, Park SH, Dandamudi DB, Shrestha E, Pack M, Lee HW, Keler T, Steinman RM, Park CG.

Blood. 2010 Nov 11;116(19):3828-38. doi: 10.1182/blood-2010-06-288068. Epub 2010 Jul 28.

44.

Visualization in transportation: challenges and opportunities for everyone.

Pack ML.

IEEE Comput Graph Appl. 2010 Jul-Aug;30(4):90-6. doi: 10.1109/MCG.2010.79.

PMID:
20650731
45.

CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations.

Zheng X, Xu C, Di Lorenzo A, Kleaveland B, Zou Z, Seiler C, Chen M, Cheng L, Xiao J, He J, Pack MA, Sessa WC, Kahn ML.

J Clin Invest. 2010 Aug;120(8):2795-804. doi: 10.1172/JCI39679. Epub 2010 Jul 1.

46.

Differential effects of thin and thick filament disruption on zebrafish smooth muscle regulatory proteins.

Davuluri G, Seiler C, Abrams J, Soriano AJ, Pack M.

Neurogastroenterol Motil. 2010 Oct;22(10):1100-e285. doi: 10.1111/j.1365-2982.2010.01545.x. Epub 2010 Jun 28.

47.

Validation of egg yolk antibody based C-ELISA for avian influenza surveillance in breeder duck.

Jeong OM, Kim MC, Kang HM, Ha GW, Oh JS, Yoo JE, Park CH, Kwon JS, Pack MR, Kim HR, Kim YJ, Kwon JH, Lee YJ.

Vet Microbiol. 2010 Aug 26;144(3-4):287-92. doi: 10.1016/j.vetmic.2010.01.022. Epub 2010 Feb 1.

PMID:
20227200
48.

Reiterative use of the notch signal during zebrafish intrahepatic biliary development.

Lorent K, Moore JC, Siekmann AF, Lawson N, Pack M.

Dev Dyn. 2010 Mar;239(3):855-64. doi: 10.1002/dvdy.22220.

49.

Glycerol monolaurate inhibits Candida and Gardnerella vaginalis in vitro and in vivo but not Lactobacillus.

Strandberg KL, Peterson ML, Lin YC, Pack MC, Chase DJ, Schlievert PM.

Antimicrob Agents Chemother. 2010 Feb;54(2):597-601. doi: 10.1128/AAC.01151-09. Epub 2009 Dec 14.

50.

Reduction in Staphylococcus aureus growth and exotoxin production and in vaginal interleukin 8 levels due to glycerol monolaurate in tampons.

Strandberg KL, Peterson ML, Schaefers MM, Case LC, Pack MC, Chase DJ, Schlievert PM.

Clin Infect Dis. 2009 Dec 1;49(11):1711-7. doi: 10.1086/644614.

PMID:
19863450

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