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Computed tomography-guided microcoil placement for localizing small pulmonary nodules before uniportal video-assisted thoracoscopic resection.

Refai M, Andolfi M, Barbisan F, Roncon A, Guiducci GM, Xiumè F, Salati M, Tiberi M, Giovagnoni A, Paci E.

Radiol Med. 2019 Sep 17. doi: 10.1007/s11547-019-01077-x. [Epub ahead of print]


Smoking cessation in the ITALUNG lung cancer screening: what does "teachable moment" mean?

Pistelli F, Aquilini F, Falaschi F, Puliti D, Ocello C, Lopes Pegna A, Carozzi FM, Picozzi G, Zappa M, Mascalchi M, Paci E, Carrozzi L; ITALUNG Working Group.

Nicotine Tob Res. 2019 Aug 23. pii: ntz148. doi: 10.1093/ntr/ntz148. [Epub ahead of print]


Activation of PKA via asymmetric allosteric coupling of structurally conserved cyclic nucleotide binding domains.

Hao Y, England JP, Bellucci L, Paci E, Hodges HC, Taylor SS, Maillard RA.

Nat Commun. 2019 Sep 4;10(1):3984. doi: 10.1038/s41467-019-11930-2.


The role of grade of injury in non-operative management of blunt hepatic and splenic trauma: Case series from a multicenter experience.

Ruscelli P, Gemini A, Rimini M, Santella S, Candelari R, Rosati M, Paci E, Marconi V, Renzi C, Commissari R, Cirocchi R, Santoro A, D'Andrea V, Parisi A.

Medicine (Baltimore). 2019 Aug;98(35):e16746. doi: 10.1097/MD.0000000000016746.


A simple cyst is not always simply a cyst: A case of cystic recurrence after nephrectomy for tubulocystic renal cell carcinoma and literature review.

Salvatori F, Macchini M, Misericordia M, Paci E, Giovagnoni A, Candelari R.

Urologia. 2019 Aug 23:391560319870091. doi: 10.1177/0391560319870091. [Epub ahead of print]


Levels of Urinary Biomarkers of Oxidatively Generated Damage to DNA and RNA in Different Groups of Workers Compared to General Population.

Tranfo G, Paci E, Carrieri M, Marchetti E, Sisto R, Gherardi M, Costabile F, Bauleo L, Ancona C, Pigini D.

Int J Environ Res Public Health. 2019 Aug 20;16(16). pii: E2995. doi: 10.3390/ijerph16162995.


RE: Expected Monetary Impact of Oncotype DX Score-Concordant Systemic Breast Cancer Therapy Based on the TAILORx Trial.

Rossi PG, Paci E.

J Natl Cancer Inst. 2019 Jun 19. pii: djz125. doi: 10.1093/jnci/djz125. [Epub ahead of print] No abstract available.


Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin: X-ray crystallography and modelling study.

Lepsik M, Sommer R, Kuhaudomlarp S, Lelimousin M, Paci E, Varrot A, Titz A, Imberty A.

Eur J Med Chem. 2019 Sep 1;177:212-220. doi: 10.1016/j.ejmech.2019.05.049. Epub 2019 May 18.


Computational Modeling of Designed Ankyrin Repeat Protein Complexes with Their Targets.

Radom F, Paci E, Plückthun A.

J Mol Biol. 2019 Jul 12;431(15):2852-2868. doi: 10.1016/j.jmb.2019.05.005. Epub 2019 May 11.


Estimating Constraints for Protection Factors from HDX-MS Data.

Skinner SP, Radou G, Tuma R, Houwing-Duistermaat JJ, Paci E.

Biophys J. 2019 Apr 2;116(7):1194-1203. doi: 10.1016/j.bpj.2019.02.024. Epub 2019 Mar 5.


Directed Assembly of Homopentameric Cholera Toxin B-Subunit Proteins into Higher-Order Structures Using Coiled-Coil Appendages.

Ross JF, Wildsmith GC, Johnson M, Hurdiss DL, Hollingsworth K, Thompson RF, Mosayebi M, Trinh CH, Paci E, Pearson AR, Webb ME, Turnbull WB.

J Am Chem Soc. 2019 Apr 3;141(13):5211-5219. doi: 10.1021/jacs.8b11480. Epub 2019 Mar 21.


Allostery in Its Many Disguises: From Theory to Applications.

Wodak SJ, Paci E, Dokholyan NV, Berezovsky IN, Horovitz A, Li J, Hilser VJ, Bahar I, Karanicolas J, Stock G, Hamm P, Stote RH, Eberhardt J, Chebaro Y, Dejaegere A, Cecchini M, Changeux JP, Bolhuis PG, Vreede J, Faccioli P, Orioli S, Ravasio R, Yan L, Brito C, Wyart M, Gkeka P, Rivalta I, Palermo G, McCammon JA, Panecka-Hofman J, Wade RC, Di Pizio A, Niv MY, Nussinov R, Tsai CJ, Jang H, Padhorny D, Kozakov D, McLeish T.

Structure. 2019 Apr 2;27(4):566-578. doi: 10.1016/j.str.2019.01.003. Epub 2019 Feb 7. Review.


Circulating microRNAs as potential biomarkers of occupational exposure to low dose organic solvents.

Sisto R, Capone P, Cerini L, Sanjust F, Paci E, Pigini D, Gatto MP, Gherardi M, Gordiani A, L'Episcopo N, Tranfo G, Chiarella P.

Toxicol Rep. 2019 Jan 8;6:126-135. doi: 10.1016/j.toxrep.2019.01.001. eCollection 2019.


Effect of Benzene Exposure on the Urinary Biomarkers of Nucleic Acid Oxidation in Two Cohorts of Gasoline Pump Attendants.

Carrieri M, Pigini D, Martinelli A, Paci E, Maratini F, Salamon F, Tranfo G.

Int J Environ Res Public Health. 2019 Jan 5;16(1). pii: E129. doi: 10.3390/ijerph16010129.


Dynamic ion pair behavior stabilizes single α-helices in proteins.

Batchelor M, Wolny M, Baker EG, Paci E, Kalverda AP, Peckham M.

J Biol Chem. 2019 Mar 1;294(9):3219-3234. doi: 10.1074/jbc.RA118.006752. Epub 2018 Dec 28.


Helical Polyampholyte Sequences Have Unique Thermodynamic Properties.

Batchelor M, Paci E.

J Phys Chem B. 2018 Dec 13;122(49):11784-11791. doi: 10.1021/acs.jpcb.8b08344. Epub 2018 Oct 23.


Temporal Trends of Urinary Phthalate Concentrations in Two Populations: Effects of REACH Authorization after Five Years.

Tranfo G, Caporossi L, Pigini D, Capanna S, Papaleo B, Paci E.

Int J Environ Res Public Health. 2018 Sep 6;15(9). pii: E1950. doi: 10.3390/ijerph15091950.


The impact of mammography screening programmes on incidence of advanced breast cancer in Europe: a literature review.

Broeders MJM, Allgood P, Duffy SW, Hofvind S, Nagtegaal ID, Paci E, Moss SM, Bucchi L.

BMC Cancer. 2018 Sep 3;18(1):860. doi: 10.1186/s12885-018-4666-1. Review.


The narrow path to organized LDCT lung cancer screening programs in Europe.

Paci E.

J Thorac Dis. 2018 Jul;10(7):4556-4564. doi: 10.21037/jtd.2018.07.08. Review.


Biomonitoring of Urinary Benzene Metabolite SPMA in the General Population in Central Italy.

Tranfo G, Pigini D, Paci E, Bauleo L, Forastiere F, Ancona C.

Toxics. 2018 Jul 11;6(3). pii: E37. doi: 10.3390/toxics6030037.


Biomarkers of early genotoxicity and oxidative stress for occupational risk assessment of exposure to styrene in the fibreglass reinforced plastic industry.

Cavallo D, Tranfo G, Ursini CL, Fresegna AM, Ciervo A, Maiello R, Paci E, Pigini D, Gherardi M, Gatto MP, Buresti G, Iavicoli S.

Toxicol Lett. 2018 Dec 1;298:53-59. doi: 10.1016/j.toxlet.2018.06.006. Epub 2018 Jun 10.


Assessment of ab initio models of protein complexes by molecular dynamics.

Radom F, Plückthun A, Paci E.

PLoS Comput Biol. 2018 Jun 4;14(6):e1006182. doi: 10.1371/journal.pcbi.1006182. eCollection 2018 Jun. Erratum in: PLoS Comput Biol. 2018 Nov 9;14(11):e1006598.


Urinary Cotinine Concentration and Self-Reported Smoking Status in 1075 Subjects Living in Central Italy.

Paci E, Pigini D, Bauleo L, Ancona C, Forastiere F, Tranfo G.

Int J Environ Res Public Health. 2018 Apr 19;15(4). pii: E804. doi: 10.3390/ijerph15040804.


As you like it: How the same data can support manifold views of overdiagnosis in breast cancer screening.

Njor SH, Paci E, Rebolj M.

Int J Cancer. 2018 Sep 15;143(6):1287-1294. doi: 10.1002/ijc.31420. Epub 2018 Apr 25.


Screen-detected multiple primary lung cancers in the ITALUNG trial.

Mascalchi M, Comin CE, Bertelli E, Sali L, Maddau C, Zuccherelli S, Picozzi G, Carrozzi L, Grazzini M, Fontanini G, Voltolini L, Vella A, Castiglione F, Carozzi F, Paci E, Zompatori M, Lopes Pegna A, Falaschi F; ITALUNG Study Research Group.

J Thorac Dis. 2018 Feb;10(2):1058-1066. doi: 10.21037/jtd.2018.01.95.


Levels of urinary metabolites of four PAHs and cotinine determined in 1016 volunteers living in Central Italy.

Tombolini F, Pigini D, Tranfo G, Paci E, Carosi I, Marini F, Bauleo L, Ancona C, Forastiere F.

Environ Sci Pollut Res Int. 2018 Oct;25(29):28772-28779. doi: 10.1007/s11356-018-1650-x. Epub 2018 Mar 8.


[Decision aid and informed decision on breast cancer screening: the "DonnaInformata-Mammografia" project.]

Roberto A, Colombo C, Candiani G, Giordano L, Mantellini P, Paci E, Satolli R, Valenza M, Mosconi P.

Recenti Prog Med. 2018 Feb;109(2):139-142. doi: 10.1701/2865.28911. Italian.


Impaired glucocorticoid-mediated HPA axis negative feedback induced by juvenile social isolation in male rats.

Boero G, Pisu MG, Biggio F, Muredda L, Carta G, Banni S, Paci E, Follesa P, Concas A, Porcu P, Serra M.

Neuropharmacology. 2018 May 1;133:242-253. doi: 10.1016/j.neuropharm.2018.01.045. Epub 2018 Jan 31.


A mechanism for agonist activation of the glucagon-like peptide-1 (GLP-1) receptor through modelling & molecular dynamics.

Gómez Santiago C, Paci E, Donnelly D.

Biochem Biophys Res Commun. 2018 Mar 29;498(2):359-365. doi: 10.1016/j.bbrc.2018.01.110. Epub 2018 Feb 12.


European position statement on lung cancer screening.

Oudkerk M, Devaraj A, Vliegenthart R, Henzler T, Prosch H, Heussel CP, Bastarrika G, Sverzellati N, Mascalchi M, Delorme S, Baldwin DR, Callister ME, Becker N, Heuvelmans MA, Rzyman W, Infante MV, Pastorino U, Pedersen JH, Paci E, Duffy SW, de Koning H, Field JK.

Lancet Oncol. 2017 Dec;18(12):e754-e766. doi: 10.1016/S1470-2045(17)30861-6. Review.


Modulation of Rat 50-kHz Ultrasonic Vocalizations by Glucocorticoid Signaling: Possible Relevance to Reward and Motivation.

Simola N, Paci E, Serra M, Costa G, Morelli M.

Int J Neuropsychopharmacol. 2018 Jan 1;21(1):73-83. doi: 10.1093/ijnp/pyx106.


[Acting to avoid post-truth].

Paci E.

Epidemiol Prev. 2017 Sep-Dec;41(5-6):225. doi: 10.19191/EP17.5-6.P225.075. Italian. No abstract available.


Nonexponential Kinetics of Loop Formation in Proteins and Peptides: A Signature of Rugged Free Energy Landscapes?

Gowdy J, Batchelor M, Neelov I, Paci E.

J Phys Chem B. 2017 Oct 19;121(41):9518-9525. doi: 10.1021/acs.jpcb.7b07075. Epub 2017 Oct 6.


Corrigendum to "Advanced breast cancer rates in the epoch of service screening: The 400,000 women cohort study from Italy" [Eur J Cancer 75 (April 2017) 109-116].

Puliti D, Bucchi L, Mancini S, Paci E, Baracco S, Campari C, Canuti D, Cirilli C, Collina N, Conti GM, Di Felice E, Falcini F, Michiara M, Negri R, Ravaioli A, Sassoli De' Bianchi P, Serafini M, Zorzi M, Caldarella A, Cataliotti L, Zappa M; IMPACT COHORT Working Group.

Eur J Cancer. 2017 Nov;85:160. doi: 10.1016/j.ejca.2017.08.016. Epub 2017 Sep 2. No abstract available.


Personalised informed choice on evidence and controversy on mammography screening: study protocol for a randomized controlled trial.

Roberto A, Colombo C, Candiani G, Giordano L, Mantellini P, Paci E, Satolli R, Valenza M, Mosconi P.

BMC Cancer. 2017 Jun 19;17(1):429. doi: 10.1186/s12885-017-3428-9.


Gating of TonB-dependent transporters by substrate-specific forced remodelling.

Hickman SJ, Cooper REM, Bellucci L, Paci E, Brockwell DJ.

Nat Commun. 2017 Apr 21;8:14804. doi: 10.1038/ncomms14804.


[Medical globalization and local culture.]

Paci E.

Recenti Prog Med. 2017 Mar;108(3):113-116. doi: 10.1701/2656.27232. Italian.


Multimodal lung cancer screening using the ITALUNG biomarker panel and low dose computed tomography. Results of the ITALUNG biomarker study.

Carozzi FM, Bisanzi S, Carrozzi L, Falaschi F, Lopes Pegna A, Mascalchi M, Picozzi G, Peluso M, Sani C, Greco L, Ocello C, Paci E; ITALUNG Working Group.

Int J Cancer. 2017 Jul 1;141(1):94-101. doi: 10.1002/ijc.30727. Epub 2017 Apr 21.


Mortality, survival and incidence rates in the ITALUNG randomised lung cancer screening trial.

Paci E, Puliti D, Lopes Pegna A, Carrozzi L, Picozzi G, Falaschi F, Pistelli F, Aquilini F, Ocello C, Zappa M, Carozzi FM, Mascalchi M; the ITALUNG Working Group.

Thorax. 2017 Sep;72(9):825-831. doi: 10.1136/thoraxjnl-2016-209825. Epub 2017 Apr 4.


Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability.

Wolny M, Batchelor M, Bartlett GJ, Baker EG, Kurzawa M, Knight PJ, Dougan L, Woolfson DN, Paci E, Peckham M.

Sci Rep. 2017 Mar 13;7:44341. doi: 10.1038/srep44341.


Advanced breast cancer rates in the epoch of service screening: The 400,000 women cohort study from Italy.

Puliti D, Bucchi L, Mancini S, Paci E, Baracco S, Campari C, Canuti D, Cirilli C, Collina N, Conti GM, Di Felice E, Falcini F, Michiara M, Negri R, Ravaioli A, Sassoli De' Bianchi P, Serafini M, Zorzi M, Caldarella A, Cataliotti L, Zappa M; IMPACT COHORT Working Group.

Eur J Cancer. 2017 Apr;75:109-116. doi: 10.1016/j.ejca.2016.12.030. Epub 2017 Feb 20. Erratum in: Eur J Cancer. 2017 Nov;85:160.


Disorder drives cooperative folding in a multidomain protein.

Gruszka DT, Mendonça CA, Paci E, Whelan F, Hawkhead J, Potts JR, Clarke J.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11841-11846. Epub 2016 Oct 3.


Quantification of 1-hydroxypyrene, 1- and 2-hydroxynaphthalene, 3-hydroxybenzo[a]pyrene and 6-hydroxynitropyrene by HPLC-MS/MS in human urine as exposure biomarkers for environmental and occupational surveys.

Raponi F, Bauleo L, Ancona C, Forastiere F, Paci E, Pigini D, Tranfo G.

Biomarkers. 2017 Sep;22(6):575-583. doi: 10.1080/1354750X.2016.1252959. Epub 2016 Nov 8.


Adaptive free energy sampling in multidimensional collective variable space using boxed molecular dynamics.

O'Connor M, Paci E, McIntosh-Smith S, Glowacki DR.

Faraday Discuss. 2016 Dec 22;195:395-419. doi: 10.1039/c6fd00138f.


Effectiveness of HPV vaccination in women reaching screening age in Italy.

Carozzi FM, Ocello C, Burroni E, Faust H, Zappa M, Paci E, Iossa A, Bonanni P, Confortini M, Sani C.

J Clin Virol. 2016 Nov;84:74-81. doi: 10.1016/j.jcv.2016.09.011. Epub 2016 Oct 3.


Differential Effects of Hydrophobic Core Packing Residues for Thermodynamic and Mechanical Stability of a Hyperthermophilic Protein.

Tych KM, Batchelor M, Hoffmann T, Wilson MC, Hughes ML, Paci E, Brockwell DJ, Dougan L.

Langmuir. 2016 Jul 26;32(29):7392-402. doi: 10.1021/acs.langmuir.6b01550. Epub 2016 Jul 13.


[Planning research and surveillance after natural disasters: outcome of the scientific publications about L'Aquila (Central Italy) and other places struck by an earthquake].

Terracini B, Bisanti L, Fabiani L, Valenti M, Paci E.

Epidemiol Prev. 2016 Mar-Apr;40(2 Suppl 1):106-8. doi: 10.19191/EP16.2S1.P106.057. Italian. No abstract available.


[Epidemiologia&Prevenzione for research and public health].

Paci E, Bisanti L, Terracini B.

Epidemiol Prev. 2016 Mar-Apr;40(2 Suppl 1):10-1. doi: 10.19191/EP16.2S1.P010.042. Italian. No abstract available.


Does UKLS strategy increase the yield of screen-detected lung cancers? A comparison with ITALUNG.

Mascalchi M, Lopes Pegna A, Carrozzi L, Carozzi F, Falaschi F, Picozzi G, Paci E.

Thorax. 2016 Oct;71(10):950-1. doi: 10.1136/thoraxjnl-2016-208409. Epub 2016 May 23. No abstract available.


Characterization of the flexibility of the peripheral stalk of prokaryotic rotary A-ATPases by atomistic simulations.

Papachristos K, Muench SP, Paci E.

Proteins. 2016 Sep;84(9):1203-12. doi: 10.1002/prot.25066. Epub 2016 Jun 1.

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